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The map label for this gene is tldD [H]

Identifier: 78223916

GI number: 78223916

Start: 3072156

End: 3073538

Strand: Direct

Name: tldD [H]

Synonym: Gmet_2720

Alternate gene names: 78223916

Gene position: 3072156-3073538 (Clockwise)

Preceding gene: 78223915

Following gene: 78223917

Centisome position: 76.85

GC content: 64.86

Gene sequence:

>1383_bases
ATGCTTGACGGAATGAACCTGAGTGTCATCCTGCGCCGCGCCCTTGCGGGAGGCGGTGAATTCGCGGACATATACTACGA
GGAGGGCTCAAGCACCTCCATTATCTGCGAAGACGGAAAGATTGAGAAAGTCCTCGCCGGCACCGATCGGGGGGTGGGGA
TCAGGGTCATCTCGGACCTGCGCACCGCCTACGCCTACACCAACGAGGTGACCGAAACGGCCCTCCTGGCGCTGGCTGAG
ACCGTGAGCAGGGCGGTAAAGGGAGAGCAGTTCGGCCGCGCCATCGACATGCGGACGAAGCTCGTTGGACCGGGCTTCCC
CATCGAGATTCCGCCAGATAACGTACCACTTCAGGACAAAGTTGCGCTCGTGAACCGGGGCGACGCGGCGGCGCGCGGTT
TCGACAAAAGAATACGCCAAGTTACGGCCGTCTACCGCGACGGCGCCGTCAAAACTCAGATCGCCAATTCGCTTGGTGAT
TTCACGGAGGCTCTCCGGACCGGCACCCTCTTCCTGACGCAAGTAGTGGCGGCGGACGGAGATGTAATCCAGACCGGGTA
CGAGCCCGTGGGTCGATTCATGGGTCACGAGATCTTCCGGGAGCGGAGCCCCGAGGAGGTTGCCCTGGCGGCTGCCCGGA
GAGCCGTGATGATGCTCGGCGCCCGCAAGGCCCCCGGCGGGCTGATGCCGGTGGTCCTCTCTTCCGAGGCGGGGGGAACC
ATGGTCCACGAGGCCATCGGACACGGCCTCGAAGCGGACCTGGCCGGCAGCGGCATGTCGGTCTACACCGGCAAGGTGGG
GGAGCAGGTGGCCTCGCCCCTGGTGACGGTCATCGACGACGCCACGATCCCCAACGCCCGGGGCTCCTTCTCCTTCGACG
ACGAGGGGACGCCGGCCCAGCGGACCGTGCTCGTGGAAAACGGCATCCTCAAGGGATACCTCTACGACCGTCTCTCCGCC
ATGAAGGACGGGTGCGCCTCCACCGGCAACGGCCGGCGGGAGGGATACCACGCAAAGCCCATCGTCCGGATGACCAACAC
CCTGATCGCGCCGGGGGAAAGCTCGCCGGAGGAGATCGTCCGAGGGGTCGAAAAGGGGCTCTTCGTCCGCAAGATGGGTG
GCGGGCAGGTGAACACGGTTAACGGGGATTTCGTCTTCGAGGTTTCCGAGGGATACCTCATCGAAAACGGGGTGGTGACC
GAACCGGTCCGGGGTGCGACCCTCACCGGCAACGGCCCCGACGTGCTGAAAAAGATCGTGAAGGTGGGAAGCGACCTGGG
CTTCGGCATCGGCACCTGCGGCAAAGACGGCCAGGGGGTGCCGGTGTCCGATGCCCAGCCGACGCTGCTCATCGAGGAAA
TAACCGTGGGCGGAGCCGCCTGA

Upstream 100 bases:

>100_bases
ACGTATAATAGTTATTTCGCGGGAACATTAGACGCCCTCCTCAAATCGCTCGGCACCGAAATTGCTATCAAAGAGGTGTC
AGCCACGGAGTTTTCCAGCC

Downstream 100 bases:

>100_bases
CCTTTGGAAGAAACGGGACAACTATCGTGCACCATGCTGAACTGACTACAATCCAGCCGGTGGAGCTGCTTGAGGTACTC
AAATCGTACCCCTTCCTCGC

Product: microcin-processing peptidase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MLDGMNLSVILRRALAGGGEFADIYYEEGSSTSIICEDGKIEKVLAGTDRGVGIRVISDLRTAYAYTNEVTETALLALAE
TVSRAVKGEQFGRAIDMRTKLVGPGFPIEIPPDNVPLQDKVALVNRGDAAARGFDKRIRQVTAVYRDGAVKTQIANSLGD
FTEALRTGTLFLTQVVAADGDVIQTGYEPVGRFMGHEIFRERSPEEVALAAARRAVMMLGARKAPGGLMPVVLSSEAGGT
MVHEAIGHGLEADLAGSGMSVYTGKVGEQVASPLVTVIDDATIPNARGSFSFDDEGTPAQRTVLVENGILKGYLYDRLSA
MKDGCASTGNGRREGYHAKPIVRMTNTLIAPGESSPEEIVRGVEKGLFVRKMGGGQVNTVNGDFVFEVSEGYLIENGVVT
EPVRGATLTGNGPDVLKKIVKVGSDLGFGIGTCGKDGQGVPVSDAQPTLLIEEITVGGAA

Sequences:

>Translated_460_residues
MLDGMNLSVILRRALAGGGEFADIYYEEGSSTSIICEDGKIEKVLAGTDRGVGIRVISDLRTAYAYTNEVTETALLALAE
TVSRAVKGEQFGRAIDMRTKLVGPGFPIEIPPDNVPLQDKVALVNRGDAAARGFDKRIRQVTAVYRDGAVKTQIANSLGD
FTEALRTGTLFLTQVVAADGDVIQTGYEPVGRFMGHEIFRERSPEEVALAAARRAVMMLGARKAPGGLMPVVLSSEAGGT
MVHEAIGHGLEADLAGSGMSVYTGKVGEQVASPLVTVIDDATIPNARGSFSFDDEGTPAQRTVLVENGILKGYLYDRLSA
MKDGCASTGNGRREGYHAKPIVRMTNTLIAPGESSPEEIVRGVEKGLFVRKMGGGQVNTVNGDFVFEVSEGYLIENGVVT
EPVRGATLTGNGPDVLKKIVKVGSDLGFGIGTCGKDGQGVPVSDAQPTLLIEEITVGGAA
>Mature_460_residues
MLDGMNLSVILRRALAGGGEFADIYYEEGSSTSIICEDGKIEKVLAGTDRGVGIRVISDLRTAYAYTNEVTETALLALAE
TVSRAVKGEQFGRAIDMRTKLVGPGFPIEIPPDNVPLQDKVALVNRGDAAARGFDKRIRQVTAVYRDGAVKTQIANSLGD
FTEALRTGTLFLTQVVAADGDVIQTGYEPVGRFMGHEIFRERSPEEVALAAARRAVMMLGARKAPGGLMPVVLSSEAGGT
MVHEAIGHGLEADLAGSGMSVYTGKVGEQVASPLVTVIDDATIPNARGSFSFDDEGTPAQRTVLVENGILKGYLYDRLSA
MKDGCASTGNGRREGYHAKPIVRMTNTLIAPGESSPEEIVRGVEKGLFVRKMGGGQVNTVNGDFVFEVSEGYLIENGVVT
EPVRGATLTGNGPDVLKKIVKVGSDLGFGIGTCGKDGQGVPVSDAQPTLLIEEITVGGAA

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=455, Percent_Identity=40.4395604395604, Blast_Score=310, Evalue=1e-85,
Organism=Escherichia coli, GI1790682, Length=430, Percent_Identity=25.5813953488372, Blast_Score=93, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 48411; Mature: 48411

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDGMNLSVILRRALAGGGEFADIYYEEGSSTSIICEDGKIEKVLAGTDRGVGIRVISDL
CCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCEEEECCCCEEEEECCCCCCCEEEHHHHH
RTAYAYTNEVTETALLALAETVSRAVKGEQFGRAIDMRTKLVGPGFPIEIPPDNVPLQDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEECCCCCCCCCCC
VALVNRGDAAARGFDKRIRQVTAVYRDGAVKTQIANSLGDFTEALRTGTLFLTQVVAADG
EEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DVIQTGYEPVGRFMGHEIFRERSPEEVALAAARRAVMMLGARKAPGGLMPVVLSSEAGGT
CEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCH
MVHEAIGHGLEADLAGSGMSVYTGKVGEQVASPLVTVIDDATIPNARGSFSFDDEGTPAQ
HHHHHHCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
RTVLVENGILKGYLYDRLSAMKDGCASTGNGRREGYHAKPIVRMTNTLIAPGESSPEEIV
EEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCEEECCCCCCHHHHH
RGVEKGLFVRKMGGGQVNTVNGDFVFEVSEGYLIENGVVTEPVRGATLTGNGPDVLKKIV
HHHHHCEEEEECCCCEEEEECCCEEEEECCCEEEECCCCCCCCCCCEECCCCHHHHHHHH
KVGSDLGFGIGTCGKDGQGVPVSDAQPTLLIEEITVGGAA
HHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCC
>Mature Secondary Structure
MLDGMNLSVILRRALAGGGEFADIYYEEGSSTSIICEDGKIEKVLAGTDRGVGIRVISDL
CCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCEEEECCCCEEEEECCCCCCCEEEHHHHH
RTAYAYTNEVTETALLALAETVSRAVKGEQFGRAIDMRTKLVGPGFPIEIPPDNVPLQDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEECCCCCCCCCCC
VALVNRGDAAARGFDKRIRQVTAVYRDGAVKTQIANSLGDFTEALRTGTLFLTQVVAADG
EEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DVIQTGYEPVGRFMGHEIFRERSPEEVALAAARRAVMMLGARKAPGGLMPVVLSSEAGGT
CEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCH
MVHEAIGHGLEADLAGSGMSVYTGKVGEQVASPLVTVIDDATIPNARGSFSFDDEGTPAQ
HHHHHHCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
RTVLVENGILKGYLYDRLSAMKDGCASTGNGRREGYHAKPIVRMTNTLIAPGESSPEEIV
EEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCEEECCCCCCHHHHH
RGVEKGLFVRKMGGGQVNTVNGDFVFEVSEGYLIENGVVTEPVRGATLTGNGPDVLKKIV
HHHHHCEEEEECCCCEEEEECCCEEEEECCCEEEECCCCCCCCCCCEECCCCHHHHHHHH
KVGSDLGFGIGTCGKDGQGVPVSDAQPTLLIEEITVGGAA
HHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]