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The map label for this gene is trxA [H]

Identifier: 78223848

GI number: 78223848

Start: 2999607

End: 3000647

Strand: Reverse

Name: trxA [H]

Synonym: Gmet_2652

Alternate gene names: 78223848

Gene position: 3000647-2999607 (Counterclockwise)

Preceding gene: 78223849

Following gene: 78223847

Centisome position: 75.06

GC content: 62.06

Gene sequence:

>1041_bases
ATGAAAAAAACCCTGCCACAGCTCGTCATTATGTCGGTTCTCTGCCTGCTGGCCGCTTTGCCGGCCTTGGCCCAGGAGGA
GATTCCCGCCGCGGCCAAGGAGCGCTTTAAAGCGGGGCTGGCCCTGATCGAGAAGGCGGACAAATCGGCTGATTTCCTGG
CCGCCCTGGCCGAGTTCGAGGCGGCCGCCGCCCTGGCCCCCACGTGGCCCGACAGCCACTACAACCTGGCGCAGCTGGCC
GCCGAGTCGGACAAACCGGCCAAGGCCATCAAGGAGTATCGCGCCTATCTGGCCCTGAAACCGGACGCGGCCGACCGGGG
CGCGGTCGAGGCGGAAATGGCGCGGATGAAGGAGCTGATCGCCCTGAAGCGGAAGGTGGGGCTGCCGGGGGTCACCTTTG
CCGCCATGGCCGACGGCATCTGGGTGCTCCAGGTCCTGCCGGGGGCCGGCATCGAAAAAACCGGACTGAGGAAGGGACAC
CAAATAGTTGGCGTTGGCGGCAAGCCGCTTGCGGGCAACAAACTGGAAGATCTTTTCAAGGCCATCGAAGCCAACAACAT
TACCGACACAATGTCCAGAGGGTCCTCTGAGCGCATGTACAGCCGGATGACCCGCGACACCAAGACGCAGGGGCCGGTAG
TCGTGCTCAATGTGAAGCAGTCCCGACAGCAGGAGAAGCCTTTTCTGATCCTCTGCAAGAAAGAGATGTTCCGCTCTAAA
ATCATCGAGATCGAAGAGGACGAGTTCGAGGATGAAGTGCTCAAGGCGCCCCTGCCGGTGGCGGTCACCTTCTGGGGCGA
TTCGTGCGAGCCGTGCAAGGAATTCGTCCCCGTTCTGGAGGCGGAAAGCGCCAAGTACGCCGGCAAGGTGAAATTCGTGA
ACATCAACGTGGACGGGAACAGGAAGCTGGCTGACCAACTGGCGGTCAAGGAAGTCCCGGCCCTGATGGTGTACAAGGGG
GGGAGTGCTGTAGCGACCGCGACCGGCAAGCTTCCAAGGGAGAAGGTTGCTGAGATGCTGCAGGACGCTGCCGGCAGGTA
G

Upstream 100 bases:

>100_bases
CCGTACTTTGTCGTTACCCCGCTGCAGATGCACAAAAATGACGGTAACAGCGATTGAAACCGGAGATGTCCCGCCCACTG
GGCCGCGAAAGGATCAAACC

Downstream 100 bases:

>100_bases
TTGAGAGAGAAAGAGAAGCGATGAACCCCGAATGGCTGGTGCCGTATCTGCTGGTCGCCCTGCTGGTTTTCCTGATGCCA
AAAATATTCGGGATGCTGGG

Product: thioredoxin-related protein

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKKTLPQLVIMSVLCLLAALPALAQEEIPAAAKERFKAGLALIEKADKSADFLAALAEFEAAAALAPTWPDSHYNLAQLA
AESDKPAKAIKEYRAYLALKPDAADRGAVEAEMARMKELIALKRKVGLPGVTFAAMADGIWVLQVLPGAGIEKTGLRKGH
QIVGVGGKPLAGNKLEDLFKAIEANNITDTMSRGSSERMYSRMTRDTKTQGPVVVLNVKQSRQQEKPFLILCKKEMFRSK
IIEIEEDEFEDEVLKAPLPVAVTFWGDSCEPCKEFVPVLEAESAKYAGKVKFVNINVDGNRKLADQLAVKEVPALMVYKG
GSAVATATGKLPREKVAEMLQDAAGR

Sequences:

>Translated_346_residues
MKKTLPQLVIMSVLCLLAALPALAQEEIPAAAKERFKAGLALIEKADKSADFLAALAEFEAAAALAPTWPDSHYNLAQLA
AESDKPAKAIKEYRAYLALKPDAADRGAVEAEMARMKELIALKRKVGLPGVTFAAMADGIWVLQVLPGAGIEKTGLRKGH
QIVGVGGKPLAGNKLEDLFKAIEANNITDTMSRGSSERMYSRMTRDTKTQGPVVVLNVKQSRQQEKPFLILCKKEMFRSK
IIEIEEDEFEDEVLKAPLPVAVTFWGDSCEPCKEFVPVLEAESAKYAGKVKFVNINVDGNRKLADQLAVKEVPALMVYKG
GSAVATATGKLPREKVAEMLQDAAGR
>Mature_346_residues
MKKTLPQLVIMSVLCLLAALPALAQEEIPAAAKERFKAGLALIEKADKSADFLAALAEFEAAAALAPTWPDSHYNLAQLA
AESDKPAKAIKEYRAYLALKPDAADRGAVEAEMARMKELIALKRKVGLPGVTFAAMADGIWVLQVLPGAGIEKTGLRKGH
QIVGVGGKPLAGNKLEDLFKAIEANNITDTMSRGSSERMYSRMTRDTKTQGPVVVLNVKQSRQQEKPFLILCKKEMFRSK
IIEIEEDEFEDEVLKAPLPVAVTFWGDSCEPCKEFVPVLEAESAKYAGKVKFVNINVDGNRKLADQLAVKEVPALMVYKG
GSAVATATGKLPREKVAEMLQDAAGR

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788936, Length=112, Percent_Identity=30.3571428571429, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87082331, Length=103, Percent_Identity=33.9805825242718, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 37507; Mature: 37507

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: PS50106 PDZ ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTLPQLVIMSVLCLLAALPALAQEEIPAAAKERFKAGLALIEKADKSADFLAALAEFE
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AAAALAPTWPDSHYNLAQLAAESDKPAKAIKEYRAYLALKPDAADRGAVEAEMARMKELI
HHHHCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHH
ALKRKVGLPGVTFAAMADGIWVLQVLPGAGIEKTGLRKGHQIVGVGGKPLAGNKLEDLFK
HHHHHCCCCCCHHHHHHCCEEEEEECCCCCCCHHHCCCCCEEEECCCCCCCCCHHHHHHH
AIEANNITDTMSRGSSERMYSRMTRDTKTQGPVVVLNVKQSRQQEKPFLILCKKEMFRSK
HHHCCCCHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEHHHHHHCCCEEEEECHHHHHHH
IIEIEEDEFEDEVLKAPLPVAVTFWGDSCEPCKEFVPVLEAESAKYAGKVKFVNINVDGN
CCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCEEEEEEEEECCC
RKLADQLAVKEVPALMVYKGGSAVATATGKLPREKVAEMLQDAAGR
HHHHHHHHHHHCCEEEEEECCCEEEECCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKTLPQLVIMSVLCLLAALPALAQEEIPAAAKERFKAGLALIEKADKSADFLAALAEFE
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AAAALAPTWPDSHYNLAQLAAESDKPAKAIKEYRAYLALKPDAADRGAVEAEMARMKELI
HHHHCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHH
ALKRKVGLPGVTFAAMADGIWVLQVLPGAGIEKTGLRKGHQIVGVGGKPLAGNKLEDLFK
HHHHHCCCCCCHHHHHHCCEEEEEECCCCCCCHHHCCCCCEEEECCCCCCCCCHHHHHHH
AIEANNITDTMSRGSSERMYSRMTRDTKTQGPVVVLNVKQSRQQEKPFLILCKKEMFRSK
HHHCCCCHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEHHHHHHCCCEEEEECHHHHHHH
IIEIEEDEFEDEVLKAPLPVAVTFWGDSCEPCKEFVPVLEAESAKYAGKVKFVNINVDGN
CCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCEEEEEEEEECCC
RKLADQLAVKEVPALMVYKGGSAVATATGKLPREKVAEMLQDAAGR
HHHHHHHHHHHCCEEEEEECCCEEEECCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]