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The map label for this gene is yaeR [C]

Identifier: 78223845

GI number: 78223845

Start: 2997490

End: 2997870

Strand: Direct

Name: yaeR [C]

Synonym: Gmet_2649

Alternate gene names: 78223845

Gene position: 2997490-2997870 (Clockwise)

Preceding gene: 78223844

Following gene: 78223846

Centisome position: 74.99

GC content: 56.69

Gene sequence:

>381_bases
ATGTTCAAACGGATTGACCATGTGGAAATCATCCCCCGCGATTTCGAAAGAGCTATCGGCTTCTACACGGAGGTATTGGG
ATTCAAGGTCAGGCAACGGCTGAAGGTGGAAGCCCCTCCCCTCGAAGGAATCGCCTATCTTGAGCTTGGCGACACGGTCA
TTGAGCTGATGCAGGTCAGGGATGCCACACCGGCAGTGGTAAATCCATGGCAGACCGGCTATCGGATGATGGCCCTGGAG
GTGGAAGATATGGACCGGGCTGTGGCCTATCTTGCCGGCAAAGGGGTGGCGATCACCTGGGGACCGGTGACCTTGGGGAC
ATCCAAGAGGGCCGAGATACAGGACGCCGATGGATTCTCCATCGAATTGAGGCAGTGGTGA

Upstream 100 bases:

>100_bases
GAGATTTATGTCGCTTCATTCCTGGTGCCGGTTGTTAAGTGAATAGGATGGCGGAACATAACCATTTGCGCGGGTAAACT
AGAGATATCAGGAGTTAACC

Downstream 100 bases:

>100_bases
AAACACAAGAAAACGGAGGCACGATAATGATTCCAGAGAAAATGCTGCAAGTACTGAAACACGAGGGGGTTGTGGCCATA
GCCACACAGGGTGACGGTGG

Product: glyoxalase/bleomycin resistance protein/dioxygenase

Products: glutathione; methylglyoxal

Alternate protein names: Lactoylglutathione Lyase

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MFKRIDHVEIIPRDFERAIGFYTEVLGFKVRQRLKVEAPPLEGIAYLELGDTVIELMQVRDATPAVVNPWQTGYRMMALE
VEDMDRAVAYLAGKGVAITWGPVTLGTSKRAEIQDADGFSIELRQW

Sequences:

>Translated_126_residues
MFKRIDHVEIIPRDFERAIGFYTEVLGFKVRQRLKVEAPPLEGIAYLELGDTVIELMQVRDATPAVVNPWQTGYRMMALE
VEDMDRAVAYLAGKGVAITWGPVTLGTSKRAEIQDADGFSIELRQW
>Mature_126_residues
MFKRIDHVEIIPRDFERAIGFYTEVLGFKVRQRLKVEAPPLEGIAYLELGDTVIELMQVRDATPAVVNPWQTGYRMMALE
VEDMDRAVAYLAGKGVAITWGPVTLGTSKRAEIQDADGFSIELRQW

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.4.1.5

Molecular weight: Translated: 14285; Mature: 14285

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKRIDHVEIIPRDFERAIGFYTEVLGFKVRQRLKVEAPPLEGIAYLELGDTVIELMQVR
CCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEEEEHHHHHHHHHHHC
DATPAVVNPWQTGYRMMALEVEDMDRAVAYLAGKGVAITWGPVTLGTSKRAEIQDADGFS
CCCCCEECCCCCCEEEEEEEHHHHHHHHHHHCCCCEEEEECCEEECCCCCCCCCCCCCCE
IELRQW
EEEECC
>Mature Secondary Structure
MFKRIDHVEIIPRDFERAIGFYTEVLGFKVRQRLKVEAPPLEGIAYLELGDTVIELMQVR
CCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEEEEHHHHHHHHHHHC
DATPAVVNPWQTGYRMMALEVEDMDRAVAYLAGKGVAITWGPVTLGTSKRAEIQDADGFS
CCCCCEECCCCCCEEEEEEEHHHHHHHHHHHCCCCEEEEECCEEECCCCCCCCCCCCCCE
IELRQW
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA