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The map label for this gene is gacS [H]

Identifier: 78223839

GI number: 78223839

Start: 2989635

End: 2993285

Strand: Reverse

Name: gacS [H]

Synonym: Gmet_2642

Alternate gene names: 78223839

Gene position: 2993285-2989635 (Counterclockwise)

Preceding gene: 78223840

Following gene: 78223838

Centisome position: 74.88

GC content: 61.08

Gene sequence:

>3651_bases
ATGGGGTGGTATGCAGATCTGAAGATCAGGAACAAGCTGCTTCTCGGCTACGGAACGGTCATCGCCTTCAGTTCCCTGAT
CGGTTATTTCGGTGTCACCGGTTTGACAGAAATGAAGTCACATCTGGATGCCATGCATGACCACCTGATTCCGGGCATAG
AGACGGCGGCAATGATCGACCGCCATCACCAGCAGCATCGCCGAACGTTTTTGAACTACCTGGAGGAGAATCGCCTGCAC
CGCAAAGAGCTGGAGTTGAAACTCCACCATGAAGCGATAGACATACAGGAGTCCTTGAAACGTTACGCCAAGCTTTCGAT
TTATCCTGCGGAGAGACGACTTCTGGATGATGTCATCACTGCCTCGAAGGAATACATGGATGAGACGGCAAGACTCAAGT
CAGCGGCCGATTCAGGCGCTGACTACGAAACGCTGACTGTCGACAATGCGCACCTGAGGACTCTTTTCGGCGATGTTGAA
AACCGAGCGAAGCTGCTCACACAGTACAGCCTGAAAGAAGGGGACGAGCATCTCGACCAGAGCACCGCCGGCTACTTCAA
TATCCGCTCGTGGCTGATATCGCTCCTTCTCGGCGCTATCGCCATTGCACTGGCCATGGCGTTCTTCATCACGCGGAGCG
TGGCCGACCCCATCCGAGTGGTCCTCGATGCCGTGCGCCGGATGGAAGAGTCGGGGACGGAAAAGGCCCGGCTGGCGGAG
GCCATTGCAGCCGGCGACCTGACCCAGGACGTGGCCGTGTCGGAGCGGCTCCGGATTGATCCTGAAACCGTTGCCAGGGA
CGAGGGCGGAATGATGCTCCGGGCGGTGGCCGGCATGAGCGGCATCCAGGCATCCCTCGACGCTGCATTTTCACGGATGA
CGGACTCGCTGCGCCGGAACCGGCAGGAGGAGCAGGCACGGGACTGGCTGAAAAGTGGCGCCAATGAACTCGGCGCCATT
CTTCGGGGGGACCGGCGGCTGGAGGAAATGGTTGAAAAGAGCCTCTCTTTCCTCTGCGAATACCTGGGGGCCGGCGTCGG
TGTCCTCTATCTGTACAACGACAGGACCCGTGATCTGGAGATTGCCGCCACCTACGCCCTTGCCCGCCGGGAGGATATGA
AGAAGCGGTTTGCCCTCGGGGAGGGCTTGGTGGGGGAGGCGGCCAAGGAGAGGAGGATTATCCGCCTCGCCGATGTCCCT
CCCGGCTATCTCCCCATAAGTTCGGCCATTGGCGAGGCGAAGCCCCTCAACATCGCCGCGGTGCCGCTGCTCCATGACAA
TCTTCTCGTGGGGGTTGTGGAAATAGGCTCCTTCAGGGAATTCACGGCGCGGGAACTGGAGTTCCTCAGCCGGGCCCAGG
AGGGGCTATCCATCGGGATCAACGTCAACCGTTCGCGGAAGCTCGTGGACGAGCTGCTTGAACAGACCCAGGCCCAGACC
GAGGAGCTGCGGGTCCAGCAGGAAGAGCTCCAGCAGACCAACGAGGAGCTTGAGGAGCGGGCCCAGATGCTGGAGCAGCA
GCGGGAGCAGATCCGCGCCAAGAACCGCGAGGTGGAGGAGACGAGCCGGGCGCTGAAGCTGAAGGCCGACGAACTGGAGC
GGATCAGCACCTACAAGTCCGAATTCCTGGCCAACATGTCCCACGAACTGAGGACCCCCCTCAATAGCCTGCTGATCCTC
TCCTCTCTGCTGAAGGAAAACCGGGAGCACAACCTGACCGACAAACAGGTGGAGTACGCAGCCACCATCAACAGCTCCGG
CAACGACCTCCTTACCCTCATCAACGATATCCTCGATCTCTCGAAGATCGAGTCGGGAAGGCTGGAGTTCAATTACGAGC
AGATTCCGCTCCGCGCCCTCTTCGACCAGCTCCGCACGATGTTCTCCCCCCTCGCGGAGCAGAAGGGGCTGGACTTTGAT
GCGATCATCGAGGAGGGGGTCCCGGAAGAGATAACCACCGACGGCCAGCGGACCCAGCAGATCCTGAAGAACCTCGTTTC
CAACGCCTGCAAGTTCACCCGGGAGGGGAGGGTGGCCGTCAGGGCGCATCTGCCCAATTCAGAGGAAAATCCCCTGCCGG
CCCCGGCCATTGCCATTCAGGTTTCCGACACGGGAATCGGGATTTCTCCCGACAAGCATGACCTTGTGTTCCAGGCGTTC
CAGCAGGCGGACGGCACGACGAGCCGGAAGTTCGGCGGCACCGGGCTGGGGCTTTCCATTTCGCGGCAACTGGCGCGGGG
GCTCCATGGCGACGTCCTTCTCGAAAGCGAAGAGGGGAAAGGGAGCTCCTTCACCCTCTATCTCCCGCTGGACCACGCTG
CCCATGGGGAGGAGAGTCAAACGGCCGTGCCGCCGCCGGCGCCCCGGCTGCCTCCCGTCACGGTGCCGCGGGGGAAGGAA
GTCTCCGGAAGGGAGGCGGATGTTCAGCTCCCGACGCCGGTTCTGGCGGACGACCGCGAGAAGCTTCGTCCCGGCGAGAG
GAGCATCCTGATCATCGAGGACGATCTCTCCTTCGCCGCCATCCTGATGGATATGGTCCGTGATCGTGGCTTCCCGGCAA
TGGTTGCCGGGGACGGTGAAAGCGGCATTGCCCTTGCCGACCATTACCTGCCGAGCGCCATTGTGCTGGACGTGATGCTC
CCCCATATCGACGGCTGGGGGGTCATGAAGTGCCTCAAGGACAGCCTGAGGACCCGGCATATCCCGGTGCACTTCCTCAC
CTGCCTGGAAGACCGCCAGAAGGCACTGACCATGGGCGCCATAGGATTTGTGACCAAGCCCGTGAACAGTGCTCAGCTTG
ACGAGGTGTTCAGTACCATCGAGCACTCCCTGGCCAAAAGCGTCAGGAAGCTCCTGATCGTCGAAGACGACAGGAACGAG
GCAAAGAGCATGGAGGCGCTGCTCGGAGTGCGCGATGTGGCCATCACGGTCACCGCGACCGGAAGCGAGGCCATGGGGCT
TTTGGCCGTCGAACCCTTCGACTGCATCGTGCTTGACCTGGGCCTTTCCGACATGTCCGGCTTCGAGGTGCTGGAGAAGA
TCCAGTCCCTTGACGAAAGCCGGCGGATTCCGGTGATAATCCATTCGGGCCGGGACCTTTCCCGGGAGGACGAGCAGCGG
CTCCGCAACTATGCCGAGAGCATCATCATCAAGGGGGCCAAGAGCCCCGAGCGGCTTCTGAACGAGGTCTCGCTCTTTCT
GCACCTGGTGGAGAGCGGCATGGGACCCGAGAAGAAGAGGATGATCCGCGCGGCTCTCGACGACGAGGCGCTGCTCGAGG
GGAAAAAGGTTCTGATCGTGGATGACGACATGCGCAACATCTTCTCCCTCTCCAGCGTTCTCGCGGAGAAAAAGATGATC
GTGCTTGAGGCGGAAAACGGCAGGGAGGCCCTGGAGCGTCTCAATGGAGAGCCCGGCATCGATGTGGTGCTCATGGATAT
CATGATGCCCGAGATGGACGGTTTTGCGGCTACCCGCGCCATCAGGAAAGACCCGCGATTCGCCCGGCTCCCCATCATCG
CCCTCACGGCCAAGGCCATGAAGGGTGACCGGGACGAGTGCCTCAAGGCAGGGGCCAGCGATTACATCCAGAAGCCGGTG
GATGCGGACAAGCTCCTTTCGCTGCTGCGGGTATGGCTGTACGGTAGCTGA

Upstream 100 bases:

>100_bases
AATGCGATGTATATTGTGTGACTTGTTCATTAAGTAATATGTGCTAAGGTTAACAATTGTTGTTCCATGGACAGAACGTG
AGTGAGCGGGGGAGAGATTT

Downstream 100 bases:

>100_bases
CCATGGAACCGGATGAACTCTTCGACATCGAGATGCGTCTGCTCCTCCACGGTGTCCGTCAGGTGTACGGCCATGACTTC
ACCGACTACTCCGAGGCATC

Product: GAF sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1216; Mature: 1215

Protein sequence:

>1216_residues
MGWYADLKIRNKLLLGYGTVIAFSSLIGYFGVTGLTEMKSHLDAMHDHLIPGIETAAMIDRHHQQHRRTFLNYLEENRLH
RKELELKLHHEAIDIQESLKRYAKLSIYPAERRLLDDVITASKEYMDETARLKSAADSGADYETLTVDNAHLRTLFGDVE
NRAKLLTQYSLKEGDEHLDQSTAGYFNIRSWLISLLLGAIAIALAMAFFITRSVADPIRVVLDAVRRMEESGTEKARLAE
AIAAGDLTQDVAVSERLRIDPETVARDEGGMMLRAVAGMSGIQASLDAAFSRMTDSLRRNRQEEQARDWLKSGANELGAI
LRGDRRLEEMVEKSLSFLCEYLGAGVGVLYLYNDRTRDLEIAATYALARREDMKKRFALGEGLVGEAAKERRIIRLADVP
PGYLPISSAIGEAKPLNIAAVPLLHDNLLVGVVEIGSFREFTARELEFLSRAQEGLSIGINVNRSRKLVDELLEQTQAQT
EELRVQQEELQQTNEELEERAQMLEQQREQIRAKNREVEETSRALKLKADELERISTYKSEFLANMSHELRTPLNSLLIL
SSLLKENREHNLTDKQVEYAATINSSGNDLLTLINDILDLSKIESGRLEFNYEQIPLRALFDQLRTMFSPLAEQKGLDFD
AIIEEGVPEEITTDGQRTQQILKNLVSNACKFTREGRVAVRAHLPNSEENPLPAPAIAIQVSDTGIGISPDKHDLVFQAF
QQADGTTSRKFGGTGLGLSISRQLARGLHGDVLLESEEGKGSSFTLYLPLDHAAHGEESQTAVPPPAPRLPPVTVPRGKE
VSGREADVQLPTPVLADDREKLRPGERSILIIEDDLSFAAILMDMVRDRGFPAMVAGDGESGIALADHYLPSAIVLDVML
PHIDGWGVMKCLKDSLRTRHIPVHFLTCLEDRQKALTMGAIGFVTKPVNSAQLDEVFSTIEHSLAKSVRKLLIVEDDRNE
AKSMEALLGVRDVAITVTATGSEAMGLLAVEPFDCIVLDLGLSDMSGFEVLEKIQSLDESRRIPVIIHSGRDLSREDEQR
LRNYAESIIIKGAKSPERLLNEVSLFLHLVESGMGPEKKRMIRAALDDEALLEGKKVLIVDDDMRNIFSLSSVLAEKKMI
VLEAENGREALERLNGEPGIDVVLMDIMMPEMDGFAATRAIRKDPRFARLPIIALTAKAMKGDRDECLKAGASDYIQKPV
DADKLLSLLRVWLYGS

Sequences:

>Translated_1216_residues
MGWYADLKIRNKLLLGYGTVIAFSSLIGYFGVTGLTEMKSHLDAMHDHLIPGIETAAMIDRHHQQHRRTFLNYLEENRLH
RKELELKLHHEAIDIQESLKRYAKLSIYPAERRLLDDVITASKEYMDETARLKSAADSGADYETLTVDNAHLRTLFGDVE
NRAKLLTQYSLKEGDEHLDQSTAGYFNIRSWLISLLLGAIAIALAMAFFITRSVADPIRVVLDAVRRMEESGTEKARLAE
AIAAGDLTQDVAVSERLRIDPETVARDEGGMMLRAVAGMSGIQASLDAAFSRMTDSLRRNRQEEQARDWLKSGANELGAI
LRGDRRLEEMVEKSLSFLCEYLGAGVGVLYLYNDRTRDLEIAATYALARREDMKKRFALGEGLVGEAAKERRIIRLADVP
PGYLPISSAIGEAKPLNIAAVPLLHDNLLVGVVEIGSFREFTARELEFLSRAQEGLSIGINVNRSRKLVDELLEQTQAQT
EELRVQQEELQQTNEELEERAQMLEQQREQIRAKNREVEETSRALKLKADELERISTYKSEFLANMSHELRTPLNSLLIL
SSLLKENREHNLTDKQVEYAATINSSGNDLLTLINDILDLSKIESGRLEFNYEQIPLRALFDQLRTMFSPLAEQKGLDFD
AIIEEGVPEEITTDGQRTQQILKNLVSNACKFTREGRVAVRAHLPNSEENPLPAPAIAIQVSDTGIGISPDKHDLVFQAF
QQADGTTSRKFGGTGLGLSISRQLARGLHGDVLLESEEGKGSSFTLYLPLDHAAHGEESQTAVPPPAPRLPPVTVPRGKE
VSGREADVQLPTPVLADDREKLRPGERSILIIEDDLSFAAILMDMVRDRGFPAMVAGDGESGIALADHYLPSAIVLDVML
PHIDGWGVMKCLKDSLRTRHIPVHFLTCLEDRQKALTMGAIGFVTKPVNSAQLDEVFSTIEHSLAKSVRKLLIVEDDRNE
AKSMEALLGVRDVAITVTATGSEAMGLLAVEPFDCIVLDLGLSDMSGFEVLEKIQSLDESRRIPVIIHSGRDLSREDEQR
LRNYAESIIIKGAKSPERLLNEVSLFLHLVESGMGPEKKRMIRAALDDEALLEGKKVLIVDDDMRNIFSLSSVLAEKKMI
VLEAENGREALERLNGEPGIDVVLMDIMMPEMDGFAATRAIRKDPRFARLPIIALTAKAMKGDRDECLKAGASDYIQKPV
DADKLLSLLRVWLYGS
>Mature_1215_residues
GWYADLKIRNKLLLGYGTVIAFSSLIGYFGVTGLTEMKSHLDAMHDHLIPGIETAAMIDRHHQQHRRTFLNYLEENRLHR
KELELKLHHEAIDIQESLKRYAKLSIYPAERRLLDDVITASKEYMDETARLKSAADSGADYETLTVDNAHLRTLFGDVEN
RAKLLTQYSLKEGDEHLDQSTAGYFNIRSWLISLLLGAIAIALAMAFFITRSVADPIRVVLDAVRRMEESGTEKARLAEA
IAAGDLTQDVAVSERLRIDPETVARDEGGMMLRAVAGMSGIQASLDAAFSRMTDSLRRNRQEEQARDWLKSGANELGAIL
RGDRRLEEMVEKSLSFLCEYLGAGVGVLYLYNDRTRDLEIAATYALARREDMKKRFALGEGLVGEAAKERRIIRLADVPP
GYLPISSAIGEAKPLNIAAVPLLHDNLLVGVVEIGSFREFTARELEFLSRAQEGLSIGINVNRSRKLVDELLEQTQAQTE
ELRVQQEELQQTNEELEERAQMLEQQREQIRAKNREVEETSRALKLKADELERISTYKSEFLANMSHELRTPLNSLLILS
SLLKENREHNLTDKQVEYAATINSSGNDLLTLINDILDLSKIESGRLEFNYEQIPLRALFDQLRTMFSPLAEQKGLDFDA
IIEEGVPEEITTDGQRTQQILKNLVSNACKFTREGRVAVRAHLPNSEENPLPAPAIAIQVSDTGIGISPDKHDLVFQAFQ
QADGTTSRKFGGTGLGLSISRQLARGLHGDVLLESEEGKGSSFTLYLPLDHAAHGEESQTAVPPPAPRLPPVTVPRGKEV
SGREADVQLPTPVLADDREKLRPGERSILIIEDDLSFAAILMDMVRDRGFPAMVAGDGESGIALADHYLPSAIVLDVMLP
HIDGWGVMKCLKDSLRTRHIPVHFLTCLEDRQKALTMGAIGFVTKPVNSAQLDEVFSTIEHSLAKSVRKLLIVEDDRNEA
KSMEALLGVRDVAITVTATGSEAMGLLAVEPFDCIVLDLGLSDMSGFEVLEKIQSLDESRRIPVIIHSGRDLSREDEQRL
RNYAESIIIKGAKSPERLLNEVSLFLHLVESGMGPEKKRMIRAALDDEALLEGKKVLIVDDDMRNIFSLSSVLAEKKMIV
LEAENGREALERLNGEPGIDVVLMDIMMPEMDGFAATRAIRKDPRFARLPIIALTAKAMKGDRDECLKAGASDYIQKPVD
ADKLLSLLRVWLYGS

Specific function: Forms part of a two-component regulatory system gacA/gacS(lemA). May be involved in lesion formation, swarming and in the production of extracellular protease, syringomycin and N- acyl-L-homoserine lactone (acyl-HSL). Required for pathogenicity on bean [H

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=306, Percent_Identity=36.9281045751634, Blast_Score=183, Evalue=7e-47,
Organism=Escherichia coli, GI48994928, Length=431, Percent_Identity=30.1624129930394, Blast_Score=169, Evalue=1e-42,
Organism=Escherichia coli, GI87081816, Length=384, Percent_Identity=30.9895833333333, Blast_Score=144, Evalue=5e-35,
Organism=Escherichia coli, GI145693157, Length=257, Percent_Identity=36.1867704280156, Blast_Score=140, Evalue=4e-34,
Organism=Escherichia coli, GI1788713, Length=420, Percent_Identity=28.5714285714286, Blast_Score=138, Evalue=2e-33,
Organism=Escherichia coli, GI87082128, Length=242, Percent_Identity=26.8595041322314, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1790346, Length=273, Percent_Identity=27.1062271062271, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1786600, Length=246, Percent_Identity=28.4552845528455, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1790436, Length=257, Percent_Identity=26.8482490272374, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1788393, Length=246, Percent_Identity=26.0162601626016, Blast_Score=77, Evalue=9e-15,
Organism=Escherichia coli, GI1786912, Length=261, Percent_Identity=28.735632183908, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1788549, Length=254, Percent_Identity=23.6220472440945, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1786783, Length=258, Percent_Identity=24.031007751938, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1788550, Length=111, Percent_Identity=42.3423423423423, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1789809, Length=123, Percent_Identity=36.5853658536585, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=37.719298245614, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=140, Percent_Identity=40, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 135372; Mature: 135240

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGWYADLKIRNKLLLGYGTVIAFSSLIGYFGVTGLTEMKSHLDAMHDHLIPGIETAAMID
CCCEECEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
RHHQQHRRTFLNYLEENRLHRKELELKLHHEAIDIQESLKRYAKLSIYPAERRLLDDVIT
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHH
ASKEYMDETARLKSAADSGADYETLTVDNAHLRTLFGDVENRAKLLTQYSLKEGDEHLDQ
HHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
STAGYFNIRSWLISLLLGAIAIALAMAFFITRSVADPIRVVLDAVRRMEESGTEKARLAE
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
AIAAGDLTQDVAVSERLRIDPETVARDEGGMMLRAVAGMSGIQASLDAAFSRMTDSLRRN
HHHHCCCHHHHHHHHHHCCCHHHHCCCCCCEEHHHHHCCHHHHHHHHHHHHHHHHHHHHC
RQEEQARDWLKSGANELGAILRGDRRLEEMVEKSLSFLCEYLGAGVGVLYLYNDRTRDLE
CHHHHHHHHHHHCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCH
IAATYALARREDMKKRFALGEGLVGEAAKERRIIRLADVPPGYLPISSAIGEAKPLNIAA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEECCCCCCEEHHHHCCCCCCCCEEE
VPLLHDNLLVGVVEIGSFREFTARELEFLSRAQEGLSIGINVNRSRKLVDELLEQTQAQT
ECEECCCHHEEHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHH
EELRVQQEELQQTNEELEERAQMLEQQREQIRAKNREVEETSRALKLKADELERISTYKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHH
EFLANMSHELRTPLNSLLILSSLLKENREHNLTDKQVEYAATINSSGNDLLTLINDILDL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEEEEECCCCCHHHHHHHHHHHH
SKIESGRLEFNYEQIPLRALFDQLRTMFSPLAEQKGLDFDAIIEEGVPEEITTDGQRTQQ
HHCCCCCEEECHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHCCCCHHHHH
ILKNLVSNACKFTREGRVAVRAHLPNSEENPLPAPAIAIQVSDTGIGISPDKHDLVFQAF
HHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHH
QQADGTTSRKFGGTGLGLSISRQLARGLHGDVLLESEEGKGSSFTLYLPLDHAAHGEESQ
HHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCEEEEEEECCCCCCCCCCC
TAVPPPAPRLPPVTVPRGKEVSGREADVQLPTPVLADDREKLRPGERSILIIEDDLSFAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCEEEEEECCCHHHH
ILMDMVRDRGFPAMVAGDGESGIALADHYLPSAIVLDVMLPHIDGWGVMKCLKDSLRTRH
HHHHHHHCCCCCEEEECCCCCCCEEHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
IPVHFLTCLEDRQKALTMGAIGFVTKPVNSAQLDEVFSTIEHSLAKSVRKLLIVEDDRNE
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCHH
AKSMEALLGVRDVAITVTATGSEAMGLLAVEPFDCIVLDLGLSDMSGFEVLEKIQSLDES
HHHHHHHHHHEEEEEEEEECCCCCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHC
RRIPVIIHSGRDLSREDEQRLRNYAESIIIKGAKSPERLLNEVSLFLHLVESGMGPEKKR
CCCCEEEECCCCCCHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHH
MIRAALDDEALLEGKKVLIVDDDMRNIFSLSSVLAEKKMIVLEAENGREALERLNGEPGI
HHHHHCCCHHHHCCCEEEEEECCHHHHHHHHHHHHHCCEEEEECCCCHHHHHHCCCCCCC
DVVLMDIMMPEMDGFAATRAIRKDPRFARLPIIALTAKAMKGDRDECLKAGASDYIQKPV
CEEEHHHHHCCCCCHHHHHHHHCCCCHHHCCHHHHHHHHHCCCHHHHHHCCCHHHHHCCC
DADKLLSLLRVWLYGS
CHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GWYADLKIRNKLLLGYGTVIAFSSLIGYFGVTGLTEMKSHLDAMHDHLIPGIETAAMID
CCEECEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
RHHQQHRRTFLNYLEENRLHRKELELKLHHEAIDIQESLKRYAKLSIYPAERRLLDDVIT
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHH
ASKEYMDETARLKSAADSGADYETLTVDNAHLRTLFGDVENRAKLLTQYSLKEGDEHLDQ
HHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
STAGYFNIRSWLISLLLGAIAIALAMAFFITRSVADPIRVVLDAVRRMEESGTEKARLAE
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
AIAAGDLTQDVAVSERLRIDPETVARDEGGMMLRAVAGMSGIQASLDAAFSRMTDSLRRN
HHHHCCCHHHHHHHHHHCCCHHHHCCCCCCEEHHHHHCCHHHHHHHHHHHHHHHHHHHHC
RQEEQARDWLKSGANELGAILRGDRRLEEMVEKSLSFLCEYLGAGVGVLYLYNDRTRDLE
CHHHHHHHHHHHCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCH
IAATYALARREDMKKRFALGEGLVGEAAKERRIIRLADVPPGYLPISSAIGEAKPLNIAA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEECCCCCCEEHHHHCCCCCCCCEEE
VPLLHDNLLVGVVEIGSFREFTARELEFLSRAQEGLSIGINVNRSRKLVDELLEQTQAQT
ECEECCCHHEEHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHH
EELRVQQEELQQTNEELEERAQMLEQQREQIRAKNREVEETSRALKLKADELERISTYKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHH
EFLANMSHELRTPLNSLLILSSLLKENREHNLTDKQVEYAATINSSGNDLLTLINDILDL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEEEEECCCCCHHHHHHHHHHHH
SKIESGRLEFNYEQIPLRALFDQLRTMFSPLAEQKGLDFDAIIEEGVPEEITTDGQRTQQ
HHCCCCCEEECHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHCCCCHHHHH
ILKNLVSNACKFTREGRVAVRAHLPNSEENPLPAPAIAIQVSDTGIGISPDKHDLVFQAF
HHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHH
QQADGTTSRKFGGTGLGLSISRQLARGLHGDVLLESEEGKGSSFTLYLPLDHAAHGEESQ
HHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCEEEEEEECCCCCCCCCCC
TAVPPPAPRLPPVTVPRGKEVSGREADVQLPTPVLADDREKLRPGERSILIIEDDLSFAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCEEEEEECCCHHHH
ILMDMVRDRGFPAMVAGDGESGIALADHYLPSAIVLDVMLPHIDGWGVMKCLKDSLRTRH
HHHHHHHCCCCCEEEECCCCCCCEEHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
IPVHFLTCLEDRQKALTMGAIGFVTKPVNSAQLDEVFSTIEHSLAKSVRKLLIVEDDRNE
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCHH
AKSMEALLGVRDVAITVTATGSEAMGLLAVEPFDCIVLDLGLSDMSGFEVLEKIQSLDES
HHHHHHHHHHEEEEEEEEECCCCCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHC
RRIPVIIHSGRDLSREDEQRLRNYAESIIIKGAKSPERLLNEVSLFLHLVESGMGPEKKR
CCCCEEEECCCCCCHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHH
MIRAALDDEALLEGKKVLIVDDDMRNIFSLSSVLAEKKMIVLEAENGREALERLNGEPGI
HHHHHCCCHHHHCCCEEEEEECCHHHHHHHHHHHHHCCEEEEECCCCHHHHHHCCCCCCC
DVVLMDIMMPEMDGFAATRAIRKDPRFARLPIIALTAKAMKGDRDECLKAGASDYIQKPV
CEEEHHHHHCCCCCHHHHHHHHCCCCHHHCCHHHHHHHHHCCCHHHHHHCCCHHHHHCCC
DADKLLSLLRVWLYGS
CHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1314807 [H]