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The map label for this gene is cph1 [H]

Identifier: 78223836

GI number: 78223836

Start: 2986940

End: 2988130

Strand: Reverse

Name: cph1 [H]

Synonym: Gmet_2639

Alternate gene names: 78223836

Gene position: 2988130-2986940 (Counterclockwise)

Preceding gene: 78223837

Following gene: 78223831

Centisome position: 74.75

GC content: 60.03

Gene sequence:

>1191_bases
ATGGACGGACAGTTCATTTCAATGAAACCGCAGATTCTGCTTGTGGATGACCGGCCGGGAAACCTTTCGGCCCTTGAAGG
GCTTCTGGACGAGCTGGACCTGGTGTTCGTCAGAGCACTGTCGGGCAACGAAGCGCTCAGGCTGACGCTGAAGCAGGATT
TCGCGCTGGTCCTCATGGATGTGCAGATGCCCGAGATGGACGGGTTCGAGACTGCCGAGCTGATGCGCTCCAACCCCAAG
ACCAGACATCTGCCGATCATCTTCGTGACGGCGGGGATGAAGGATCTGAAGTTCCAGTTCAAGGGGTATGACGCCGGCGC
GGTCGATTACCTGGCCAAGCCCATCGAGCCGGCCATCCTCCGGAGCAAGGTACGGGTCTTCCGGGATCTCTACCTGCAGC
GCATGGAGCTGGAATTGCATCGCAGGAACCTGCAGGAGCTCGTGGACCAGAGAACCATCCAGCTCCGTCTTGCCGCCCAG
GAGCTTGAGCAGCGGGTCATCGAGCGGACCGAGGAGCTCCAGCAGGTGAACCGCCAGTTGGAATCATTCGCCTATTCGGT
CTCCCACGACCTCCGGGCGCCCCTCCGGCATATCGACGCTTTCAGCCATATCCTCATGGACGACTATTCCCAGGCCCTTG
ACGAGGAGGCCCGCAATTTGCTCCACCGCATCGTGGCGGGGTGCGACAACATGGGAAAGCTCATCGATGCCATCCTCGCC
CTCTCGCGGACCGTGCGCCAGCCCCTCAACAAAATGCCCGTGTCGATGGAACGGCTGGCGCGGGAAACGTTTGCACAGTA
TCGGGAGCAGTATGAAGGGAAAGAGATTTCGTTTACGGTTGCCGAGCTTCCCGAATCCCAGGCCGACCCAGTTCTGCTGC
GGCAGGTCTATGCGAACCTGATCGGCAATGCCCTGAAATACAGCAGCAGGCGTGAGGTGCCCAGGATCGAGGTGGGGGCG
TTTCCGGACAACGGGGAGACGGTCTACTTTGTCCGGGACAACGGCGTAGGCTTTGACATGCGGTATGCCGACAAGCTCTT
TGCGGTCTTCCAGCGACTGCACAACGGAAGCGAGTATGAAGGGACAGGGGTCGGCCTTGCCATCGCCCAGAACATCATCC
AGCGCCACGGCGGAAAGATCTGGGCGGAAGCCGAACCGGACAAGGGGGCGACGTTCTTTTTTACCCTCTGA

Upstream 100 bases:

>100_bases
TGACGGAGCCTCAGGAATGAATTCGGGCATGGAGGCCGGCTGACGCGGGCCGTCAGCGTAATCCAAGGGGCGAGCCTGTC
TCGCGGGTAATGGAGGGGAG

Downstream 100 bases:

>100_bases
CAGTCACAGCGCTCGTTCATGCAGAAAACCAAAGGCCCGCCGGAAAATTCCGACGGGCCTTTGTGTGTAACAGGAGACTG
GGCGTTACTCGTTCCACCCT

Product: response regulator receiver sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MDGQFISMKPQILLVDDRPGNLSALEGLLDELDLVFVRALSGNEALRLTLKQDFALVLMDVQMPEMDGFETAELMRSNPK
TRHLPIIFVTAGMKDLKFQFKGYDAGAVDYLAKPIEPAILRSKVRVFRDLYLQRMELELHRRNLQELVDQRTIQLRLAAQ
ELEQRVIERTEELQQVNRQLESFAYSVSHDLRAPLRHIDAFSHILMDDYSQALDEEARNLLHRIVAGCDNMGKLIDAILA
LSRTVRQPLNKMPVSMERLARETFAQYREQYEGKEISFTVAELPESQADPVLLRQVYANLIGNALKYSSRREVPRIEVGA
FPDNGETVYFVRDNGVGFDMRYADKLFAVFQRLHNGSEYEGTGVGLAIAQNIIQRHGGKIWAEAEPDKGATFFFTL

Sequences:

>Translated_396_residues
MDGQFISMKPQILLVDDRPGNLSALEGLLDELDLVFVRALSGNEALRLTLKQDFALVLMDVQMPEMDGFETAELMRSNPK
TRHLPIIFVTAGMKDLKFQFKGYDAGAVDYLAKPIEPAILRSKVRVFRDLYLQRMELELHRRNLQELVDQRTIQLRLAAQ
ELEQRVIERTEELQQVNRQLESFAYSVSHDLRAPLRHIDAFSHILMDDYSQALDEEARNLLHRIVAGCDNMGKLIDAILA
LSRTVRQPLNKMPVSMERLARETFAQYREQYEGKEISFTVAELPESQADPVLLRQVYANLIGNALKYSSRREVPRIEVGA
FPDNGETVYFVRDNGVGFDMRYADKLFAVFQRLHNGSEYEGTGVGLAIAQNIIQRHGGKIWAEAEPDKGATFFFTL
>Mature_396_residues
MDGQFISMKPQILLVDDRPGNLSALEGLLDELDLVFVRALSGNEALRLTLKQDFALVLMDVQMPEMDGFETAELMRSNPK
TRHLPIIFVTAGMKDLKFQFKGYDAGAVDYLAKPIEPAILRSKVRVFRDLYLQRMELELHRRNLQELVDQRTIQLRLAAQ
ELEQRVIERTEELQQVNRQLESFAYSVSHDLRAPLRHIDAFSHILMDDYSQALDEEARNLLHRIVAGCDNMGKLIDAILA
LSRTVRQPLNKMPVSMERLARETFAQYREQYEGKEISFTVAELPESQADPVLLRQVYANLIGNALKYSSRREVPRIEVGA
FPDNGETVYFVRDNGVGFDMRYADKLFAVFQRLHNGSEYEGTGVGLAIAQNIIQRHGGKIWAEAEPDKGATFFFTL

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=234, Percent_Identity=29.4871794871795, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1789149, Length=273, Percent_Identity=25.6410256410256, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788549, Length=254, Percent_Identity=29.1338582677165, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1790436, Length=243, Percent_Identity=29.6296296296296, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI145693157, Length=244, Percent_Identity=27.0491803278689, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1786912, Length=247, Percent_Identity=28.3400809716599, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87081816, Length=272, Percent_Identity=26.4705882352941, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788713, Length=223, Percent_Identity=25.5605381165919, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790346, Length=216, Percent_Identity=26.8518518518519, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788279, Length=206, Percent_Identity=28.6407766990291, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082012, Length=115, Percent_Identity=33.0434782608696, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786783, Length=265, Percent_Identity=25.6603773584906, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 45237; Mature: 45237

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGQFISMKPQILLVDDRPGNLSALEGLLDELDLVFVRALSGNEALRLTLKQDFALVLMD
CCCCEEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEE
VQMPEMDGFETAELMRSNPKTRHLPIIFVTAGMKDLKFQFKGYDAGAVDYLAKPIEPAIL
CCCCCCCCCHHHHHHHCCCCCCCCCEEEEECCCHHHEEEECCCCCCHHHHHHCCCCHHHH
RSKVRVFRDLYLQRMELELHRRNLQELVDQRTIQLRLAAQELEQRVIERTEELQQVNRQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESFAYSVSHDLRAPLRHIDAFSHILMDDYSQALDEEARNLLHRIVAGCDNMGKLIDAILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LSRTVRQPLNKMPVSMERLARETFAQYREQYEGKEISFTVAELPESQADPVLLRQVYANL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEHHHCCCCCCCHHHHHHHHHHH
IGNALKYSSRREVPRIEVGAFPDNGETVYFVRDNGVGFDMRYADKLFAVFQRLHNGSEYE
HHHHHHHCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCC
GTGVGLAIAQNIIQRHGGKIWAEAEPDKGATFFFTL
CCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEC
>Mature Secondary Structure
MDGQFISMKPQILLVDDRPGNLSALEGLLDELDLVFVRALSGNEALRLTLKQDFALVLMD
CCCCEEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEE
VQMPEMDGFETAELMRSNPKTRHLPIIFVTAGMKDLKFQFKGYDAGAVDYLAKPIEPAIL
CCCCCCCCCHHHHHHHCCCCCCCCCEEEEECCCHHHEEEECCCCCCHHHHHHCCCCHHHH
RSKVRVFRDLYLQRMELELHRRNLQELVDQRTIQLRLAAQELEQRVIERTEELQQVNRQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESFAYSVSHDLRAPLRHIDAFSHILMDDYSQALDEEARNLLHRIVAGCDNMGKLIDAILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LSRTVRQPLNKMPVSMERLARETFAQYREQYEGKEISFTVAELPESQADPVLLRQVYANL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEHHHCCCCCCCHHHHHHHHHHH
IGNALKYSSRREVPRIEVGAFPDNGETVYFVRDNGVGFDMRYADKLFAVFQRLHNGSEYE
HHHHHHHCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCC
GTGVGLAIAQNIIQRHGGKIWAEAEPDKGATFFFTL
CCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]