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The map label for this gene is dnaC [H]

Identifier: 78223765

GI number: 78223765

Start: 2915682

End: 2917052

Strand: Reverse

Name: dnaC [H]

Synonym: Gmet_2568

Alternate gene names: 78223765

Gene position: 2917052-2915682 (Counterclockwise)

Preceding gene: 78223766

Following gene: 78223764

Centisome position: 72.97

GC content: 62.51

Gene sequence:

>1371_bases
ATGTCCGCAGTAGACCTGAGAAAAGTTCCTCCCCAGAGCATTGAGGCCGAGATGTCGATCCTCGGCGGGATTCTCCTCGA
AAACGAGGCGATCAACCGCGCCCTGGAGATCATCGAGGCCGACGACCTCTACCGGGAGACCCACCGGAAGATTTTTCGGG
CCATGGTGGACCTCTCCACCCGCAACGAACCCTGCGACCTCATTACACTCACCGACGTGCTCAAACGCTTCGGGGAGCTG
GAGGAAGTGGGAGGGGCCGCGTACCTGGCCACCCTGGTCGATTACGTCCCCACTGCCGCCAACATCGCCTACTACTGCCG
GATGGTGAAGGAGAAGTCCATCACCCGCCGTCTCATCACCGCGGCCACCGACATCGTCACCAAGGGGTACGACGTGGAGA
CCGGGGTGGAGGAGCTTCTCGACACGGCCCAGAAGAACATCTTCGAAATTGCCGACAACAAGCTTCGCCCCGCGTTCACG
CTGGTCGGCACCATCCTCAAGGATACCTTCAAGCACATAGAGACCCTCTACGAGAAGAAGGAGCATGTCACCGGCGTCCC
CACCGGTTTCTACGACCTGGACGAGATGACTGCAGGCTTCCAGCGGGGGGACCTCATCATCATCGCCGGTCGCCCCTCCA
TGGGGAAGACCGCCTTTGCCCTCAACATCGCTCAGCATGCCGCGGCCCACGCCAGCACGCCGGCGCCGGCGGCCATCTTC
TCCCTGGAGATGAGCAAGGAGCAGCTGGTGATGCGGCTTCTCTGCTCCGAGTCCCGAGTCGACGCGAGCCGCCTGCGGAC
CGGCCATCTGGTGGATACCGACTGGCACAAGCTGACCAGCGGGGCCGACAAGCTGGCCAAGGCGAAGATGTTCATCGATG
ATACTCCGGCCATCCCGGTGCTGGAGATGCGGGCCAAGTGCCGGCGTCTCAAGGCGGAGCACGGTCTGGGGCTCATCGTG
GTCGACTATCTGCAGCTCATGCGGGGGTCGAGCACCGAGTCGCGCCAGCAGGAGATCTCGGAGATATCCCGCTCCCTCAA
GGCCCTGGCCAAGGAACTGGACGTGCCGGTGGTGGCCCTGTCGCAGCTGAACCGCTCCCTGGAGAGCCGCACCGACAAGC
GCCCCATCATGAGCGACCTGCGGGAATCGGGCGCCATCGAGCAGGACGCCGACGTGATCATGTTCGTCTACCGGGACGCC
GTCTACTGCGACGACTGCAAGAAGCGGGACGGCTCCTGCACCAAGGAGCACGACAAGGACGCCGAGATCATCATCGGCAA
GCAGCGTAACGGCCCCATCGGAACGGTAAAGCTCCTGTTCAACGGCCAGTACACCAAGTTCGAAAACCTGGAGAAACGTC
ATGACTACTAG

Upstream 100 bases:

>100_bases
AGGCGGGTCAAAATCGTTGACCGGGTAGGCGGCGCGAGTTATAGTACCCCCTTCCCCCACTTGCTTCCGGCATTCGTTTT
AAACATTCCCAAGGCAGGCC

Downstream 100 bases:

>100_bases
CATCCATCCTTCAGCACAGATAAGCCCCTCCGCCACCATCGCCGACGGCGTTGAGATCGGCGCCAACGTCATCGTGGGGG
ACCATTCCTCCATCGGCGCC

Product: primary replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MSAVDLRKVPPQSIEAEMSILGGILLENEAINRALEIIEADDLYRETHRKIFRAMVDLSTRNEPCDLITLTDVLKRFGEL
EEVGGAAYLATLVDYVPTAANIAYYCRMVKEKSITRRLITAATDIVTKGYDVETGVEELLDTAQKNIFEIADNKLRPAFT
LVGTILKDTFKHIETLYEKKEHVTGVPTGFYDLDEMTAGFQRGDLIIIAGRPSMGKTAFALNIAQHAAAHASTPAPAAIF
SLEMSKEQLVMRLLCSESRVDASRLRTGHLVDTDWHKLTSGADKLAKAKMFIDDTPAIPVLEMRAKCRRLKAEHGLGLIV
VDYLQLMRGSSTESRQQEISEISRSLKALAKELDVPVVALSQLNRSLESRTDKRPIMSDLRESGAIEQDADVIMFVYRDA
VYCDDCKKRDGSCTKEHDKDAEIIIGKQRNGPIGTVKLLFNGQYTKFENLEKRHDY

Sequences:

>Translated_456_residues
MSAVDLRKVPPQSIEAEMSILGGILLENEAINRALEIIEADDLYRETHRKIFRAMVDLSTRNEPCDLITLTDVLKRFGEL
EEVGGAAYLATLVDYVPTAANIAYYCRMVKEKSITRRLITAATDIVTKGYDVETGVEELLDTAQKNIFEIADNKLRPAFT
LVGTILKDTFKHIETLYEKKEHVTGVPTGFYDLDEMTAGFQRGDLIIIAGRPSMGKTAFALNIAQHAAAHASTPAPAAIF
SLEMSKEQLVMRLLCSESRVDASRLRTGHLVDTDWHKLTSGADKLAKAKMFIDDTPAIPVLEMRAKCRRLKAEHGLGLIV
VDYLQLMRGSSTESRQQEISEISRSLKALAKELDVPVVALSQLNRSLESRTDKRPIMSDLRESGAIEQDADVIMFVYRDA
VYCDDCKKRDGSCTKEHDKDAEIIIGKQRNGPIGTVKLLFNGQYTKFENLEKRHDY
>Mature_455_residues
SAVDLRKVPPQSIEAEMSILGGILLENEAINRALEIIEADDLYRETHRKIFRAMVDLSTRNEPCDLITLTDVLKRFGELE
EVGGAAYLATLVDYVPTAANIAYYCRMVKEKSITRRLITAATDIVTKGYDVETGVEELLDTAQKNIFEIADNKLRPAFTL
VGTILKDTFKHIETLYEKKEHVTGVPTGFYDLDEMTAGFQRGDLIIIAGRPSMGKTAFALNIAQHAAAHASTPAPAAIFS
LEMSKEQLVMRLLCSESRVDASRLRTGHLVDTDWHKLTSGADKLAKAKMFIDDTPAIPVLEMRAKCRRLKAEHGLGLIVV
DYLQLMRGSSTESRQQEISEISRSLKALAKELDVPVVALSQLNRSLESRTDKRPIMSDLRESGAIEQDADVIMFVYRDAV
YCDDCKKRDGSCTKEHDKDAEIIIGKQRNGPIGTVKLLFNGQYTKFENLEKRHDY

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=449, Percent_Identity=50.3340757238307, Blast_Score=425, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 50989; Mature: 50858

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVDLRKVPPQSIEAEMSILGGILLENEAINRALEIIEADDLYRETHRKIFRAMVDLST
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RNEPCDLITLTDVLKRFGELEEVGGAAYLATLVDYVPTAANIAYYCRMVKEKSITRRLIT
CCCCCCEEEHHHHHHHHCCHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
AATDIVTKGYDVETGVEELLDTAQKNIFEIADNKLRPAFTLVGTILKDTFKHIETLYEKK
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EHVTGVPTGFYDLDEMTAGFQRGDLIIIAGRPSMGKTAFALNIAQHAAAHASTPAPAAIF
HHCCCCCCCCCCHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHE
SLEMSKEQLVMRLLCSESRVDASRLRTGHLVDTDWHKLTSGADKLAKAKMFIDDTPAIPV
EECCCHHHHHHHHHHCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCHH
LEMRAKCRRLKAEHGLGLIVVDYLQLMRGSSTESRQQEISEISRSLKALAKELDVPVVAL
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
SQLNRSLESRTDKRPIMSDLRESGAIEQDADVIMFVYRDAVYCDDCKKRDGSCTKEHDKD
HHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEEEEHHCCHHHCHHHCCCCCCCCCCCCC
AEIIIGKQRNGPIGTVKLLFNGQYTKFENLEKRHDY
CEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHCCC
>Mature Secondary Structure 
SAVDLRKVPPQSIEAEMSILGGILLENEAINRALEIIEADDLYRETHRKIFRAMVDLST
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RNEPCDLITLTDVLKRFGELEEVGGAAYLATLVDYVPTAANIAYYCRMVKEKSITRRLIT
CCCCCCEEEHHHHHHHHCCHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
AATDIVTKGYDVETGVEELLDTAQKNIFEIADNKLRPAFTLVGTILKDTFKHIETLYEKK
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EHVTGVPTGFYDLDEMTAGFQRGDLIIIAGRPSMGKTAFALNIAQHAAAHASTPAPAAIF
HHCCCCCCCCCCHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHE
SLEMSKEQLVMRLLCSESRVDASRLRTGHLVDTDWHKLTSGADKLAKAKMFIDDTPAIPV
EECCCHHHHHHHHHHCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCHH
LEMRAKCRRLKAEHGLGLIVVDYLQLMRGSSTESRQQEISEISRSLKALAKELDVPVVAL
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
SQLNRSLESRTDKRPIMSDLRESGAIEQDADVIMFVYRDAVYCDDCKKRDGSCTKEHDKD
HHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEEEEHHCCHHHCHHHCCCCCCCCCCCCC
AEIIIGKQRNGPIGTVKLLFNGQYTKFENLEKRHDY
CEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]