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The map label for this gene is yeeO [C]

Identifier: 78223708

GI number: 78223708

Start: 2847872

End: 2849263

Strand: Direct

Name: yeeO [C]

Synonym: Gmet_2508

Alternate gene names: 78223708

Gene position: 2847872-2849263 (Clockwise)

Preceding gene: 78223705

Following gene: 78223709

Centisome position: 71.24

GC content: 64.94

Gene sequence:

>1392_bases
ATGACCTCTCCCGACCTCATCAACGACCCCATCCCGAAGCTCCTCACCCGACTCGCCGTGCCGGTGGGGACCGGCTTTTT
CTTCAACACCATGTTCAATGTGGTGGATACCTTCTACGGAGGGCTCATCTCCACCAGGGCGCTGGCGGCACTCTCCCTCT
CCTTTCCCCTCTTTTTCATCGTCCTGGCTATCGGTGCCGGCACCTCCATGGGAGCCACGGCCCTCATCGGCCACGCATTG
GGGAGCGACCAACGGGAGGAGGCGGAGCTCTTTGCGGCCCAGGCCATCTCCTTCGGCGTCATTCATGCCCTCTTCATGAC
CGTGGGAGGAGTCGCGGCGGCGCCGGCCCTCTTCAGGCTCATGGGGGCATCGGGCGATTACCTGGACCTGGCCCTGGCCT
ACATGGATGTCATCATCGCCGGTACCGTTTTCTTCGTCGGCAACTATGTCCTCAACGCCATGCTCAACGCCTCGGGGGAT
ACGAAGAGTTTCCGCAACTTCCTGGTGGCGGGATGCTTCCTGAACATGGCTCTGGACCCCTGGTTCATGTACGGAGGGGT
GGGCGTGCCGGCCCTGGGGATACGGGGCATTGCCCTGGCCACGGTGGTGGTCCAGGCCGCGGGGAACGTCTACCTCCTGG
GTCGGGTGCGGCGGACGGGTCTTTTGTCGGGGCGCTCGTGGCAACTCCTCATGCCGCGGCGGGAGCCGTTTCGCCGCCTC
TTCGGCCAGGGGATTCCGGCAAGCATGAACATGCTGACGGTGTCGCTGGGCATGTTCGTCATCACCTGGTTCGCGGGGCG
GTTCGGCAAGGAGGTGGTGGCTGCCTACGGCATCGGCACCCGCATCGAACAGATCGTGCTCCTGCCGGCCTTTGGGCTGA
ATGTGGCGGTCCTCTCCCTCGTGGCCCAGAACTTCGGCGCAGGAAAGCTTCGCCGGATACGGGAGACCCTGACGAGGGCG
CTGCGGGCGGGGCTCCTCATGATGGCAGGGGGGACGACGCTGGTCTTTGCGGCGGCCGAGCCCCTGATGAAGCTTTTCAC
CGCCGATCCGCTGGTGGTTGCCCACGGGGTCACTTTTCTCCGGGTGGAGTCGTTGCTGCTGGGGGCCTATGTGATTCTCT
ACATGAACAATTCGGCACTCCAGGGGCTGCAGCGGCCGGCCTTCGCCCTCTGGATCGGGCTCTTCCGCCAGATCATTGTG
CCGGTGCCAATCTTCTGGCTCCTGGCCTTGGTGCTCGGCTGGGGCCCCCCCGGCATCTGGTGGGGATTCTTTCTCGTCAC
CTGGAGCGCGGCGATGGTGTCGGTCCTCTACACCCGCCGGGTGCTGCGGCTGGCAACCGAAGAGGCCGATGCGGCGCTCA
TGCGGAACGGCAACAACGGCCCGCCCCCTTGA

Upstream 100 bases:

>100_bases
GTACAATCAAAGTTTACCGGACAGTAGTACGGGCGACTAATAAATAACCAGCACCGGCTTTGAACGCACAGAGGTGCAAT
TGAATGCTACTATTGCATCC

Downstream 100 bases:

>100_bases
CTCCGGGCCGCTTCCCGCTACCCTTTACCCATGCCCGAATCGATCCTCGCCACTTTCACTGTCAAGCGCCTGGAGATCAT
CGCCCCGGACGGGACCGCCG

Product: multi anti extrusion protein MatE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MTSPDLINDPIPKLLTRLAVPVGTGFFFNTMFNVVDTFYGGLISTRALAALSLSFPLFFIVLAIGAGTSMGATALIGHAL
GSDQREEAELFAAQAISFGVIHALFMTVGGVAAAPALFRLMGASGDYLDLALAYMDVIIAGTVFFVGNYVLNAMLNASGD
TKSFRNFLVAGCFLNMALDPWFMYGGVGVPALGIRGIALATVVVQAAGNVYLLGRVRRTGLLSGRSWQLLMPRREPFRRL
FGQGIPASMNMLTVSLGMFVITWFAGRFGKEVVAAYGIGTRIEQIVLLPAFGLNVAVLSLVAQNFGAGKLRRIRETLTRA
LRAGLLMMAGGTTLVFAAAEPLMKLFTADPLVVAHGVTFLRVESLLLGAYVILYMNNSALQGLQRPAFALWIGLFRQIIV
PVPIFWLLALVLGWGPPGIWWGFFLVTWSAAMVSVLYTRRVLRLATEEADAALMRNGNNGPPP

Sequences:

>Translated_463_residues
MTSPDLINDPIPKLLTRLAVPVGTGFFFNTMFNVVDTFYGGLISTRALAALSLSFPLFFIVLAIGAGTSMGATALIGHAL
GSDQREEAELFAAQAISFGVIHALFMTVGGVAAAPALFRLMGASGDYLDLALAYMDVIIAGTVFFVGNYVLNAMLNASGD
TKSFRNFLVAGCFLNMALDPWFMYGGVGVPALGIRGIALATVVVQAAGNVYLLGRVRRTGLLSGRSWQLLMPRREPFRRL
FGQGIPASMNMLTVSLGMFVITWFAGRFGKEVVAAYGIGTRIEQIVLLPAFGLNVAVLSLVAQNFGAGKLRRIRETLTRA
LRAGLLMMAGGTTLVFAAAEPLMKLFTADPLVVAHGVTFLRVESLLLGAYVILYMNNSALQGLQRPAFALWIGLFRQIIV
PVPIFWLLALVLGWGPPGIWWGFFLVTWSAAMVSVLYTRRVLRLATEEADAALMRNGNNGPPP
>Mature_462_residues
TSPDLINDPIPKLLTRLAVPVGTGFFFNTMFNVVDTFYGGLISTRALAALSLSFPLFFIVLAIGAGTSMGATALIGHALG
SDQREEAELFAAQAISFGVIHALFMTVGGVAAAPALFRLMGASGDYLDLALAYMDVIIAGTVFFVGNYVLNAMLNASGDT
KSFRNFLVAGCFLNMALDPWFMYGGVGVPALGIRGIALATVVVQAAGNVYLLGRVRRTGLLSGRSWQLLMPRREPFRRLF
GQGIPASMNMLTVSLGMFVITWFAGRFGKEVVAAYGIGTRIEQIVLLPAFGLNVAVLSLVAQNFGAGKLRRIRETLTRAL
RAGLLMMAGGTTLVFAAAEPLMKLFTADPLVVAHGVTFLRVESLLLGAYVILYMNNSALQGLQRPAFALWIGLFRQIIVP
VPIFWLLALVLGWGPPGIWWGFFLVTWSAAMVSVLYTRRVLRLATEEADAALMRNGNNGPPP

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=428, Percent_Identity=21.7289719626168, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49768; Mature: 49637

Theoretical pI: Translated: 10.49; Mature: 10.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPDLINDPIPKLLTRLAVPVGTGFFFNTMFNVVDTFYGGLISTRALAALSLSFPLFFI
CCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAIGAGTSMGATALIGHALGSDQREEAELFAAQAISFGVIHALFMTVGGVAAAPALFRL
HHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
MGASGDYLDLALAYMDVIIAGTVFFVGNYVLNAMLNASGDTKSFRNFLVAGCFLNMALDP
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCH
WFMYGGVGVPALGIRGIALATVVVQAAGNVYLLGRVRRTGLLSGRSWQLLMPRREPFRRL
HHHCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEHHHHHCCCCCCCEEECCCHHHHHHH
FGQGIPASMNMLTVSLGMFVITWFAGRFGKEVVAAYGIGTRIEQIVLLPAFGLNVAVLSL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEECCCCHHHHHHHH
VAQNFGAGKLRRIRETLTRALRAGLLMMAGGTTLVFAAAEPLMKLFTADPLVVAHGVTFL
HHHCCCCHHHHHHHHHHHHHHHHCEEEEECCCEEEEHHHHHHHHHHCCCCHHHHHCHHHH
RVESLLLGAYVILYMNNSALQGLQRPAFALWIGLFRQIIVPVPIFWLLALVLGWGPPGIW
HHHHHHHHHHHHEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
WGFFLVTWSAAMVSVLYTRRVLRLATEEADAALMRNGNNGPPP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TSPDLINDPIPKLLTRLAVPVGTGFFFNTMFNVVDTFYGGLISTRALAALSLSFPLFFI
CCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAIGAGTSMGATALIGHALGSDQREEAELFAAQAISFGVIHALFMTVGGVAAAPALFRL
HHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
MGASGDYLDLALAYMDVIIAGTVFFVGNYVLNAMLNASGDTKSFRNFLVAGCFLNMALDP
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCH
WFMYGGVGVPALGIRGIALATVVVQAAGNVYLLGRVRRTGLLSGRSWQLLMPRREPFRRL
HHHCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEHHHHHCCCCCCCEEECCCHHHHHHH
FGQGIPASMNMLTVSLGMFVITWFAGRFGKEVVAAYGIGTRIEQIVLLPAFGLNVAVLSL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEECCCCHHHHHHHH
VAQNFGAGKLRRIRETLTRALRAGLLMMAGGTTLVFAAAEPLMKLFTADPLVVAHGVTFL
HHHCCCCHHHHHHHHHHHHHHHHCEEEEECCCEEEEHHHHHHHHHHCCCCHHHHHCHHHH
RVESLLLGAYVILYMNNSALQGLQRPAFALWIGLFRQIIVPVPIFWLLALVLGWGPPGIW
HHHHHHHHHHHHEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
WGFFLVTWSAAMVSVLYTRRVLRLATEEADAALMRNGNNGPPP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]