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The map label for this gene is kdpE [H]

Identifier: 78223640

GI number: 78223640

Start: 2760947

End: 2761648

Strand: Direct

Name: kdpE [H]

Synonym: Gmet_2437

Alternate gene names: 78223640

Gene position: 2760947-2761648 (Clockwise)

Preceding gene: 78223639

Following gene: 78223659

Centisome position: 69.07

GC content: 64.67

Gene sequence:

>702_bases
ATGCCGAAGGAAAACCGTCTACCGCGGATACTCATAGTCGATGACGAACTGGCGATACGGCGCTTCCTCTGCACCGCCCT
CGATACCGGGGAGTTTTCCCTCCACCAGGCGGAAAACGGCCATACAGCGCTGGCGGCAGCGGTTGCGACGATGCCGGACG
TGATCCTCCTCGACCTGGGGCTTCCGGATATGGACGGGGTTGAAGTCATCCGACGGATACGGGAGTGGTCCCAGGTGCCG
ATCATCGTCCTTTCCGTGCGGGAGCGTGAGGACGACAAGGTGGCTGCGCTGGATGCCGGGGCGGACGACTACCTGACCAA
GCCATTCGGCGTCGCAGAGCTTGTGGCCCGGATTCGCGCGGCACTGCGGCGCGCCTTGCAACAGGTGCCGGAACCCATCT
TCCGTTCCGGAGACCTGGAGGTGGACCTGGCGCGCCGGCGGGTAACGGTCGACGGCAGCGAGTCCCAGCTCACCCCCACC
GAGTACGAACTGCTGCGCCTCCTGGTGGTCCATGCGGGAAAGGTCCTCACCCACAGCCAGATTCTCCGGCAGATATGGGG
GGTCTCCCACCTCGAGCAACCCCACGTGCTGCGGGTGAACATCAGCAACCTGCGCCGCAAAATAGAAATGGACCCCTCCC
GTCCGCGCCACATCCTCACCGAACCCGGAGTCGGCTACCGGCTCCGGAGCGACGGCAGTTGA

Upstream 100 bases:

>100_bases
GGGATTGTCGAGGCTCACGGCGGCGCCATCCGGGCCGAAAACCGGGCACGTGGCGGATTGAGAGTAATCGTCACGTTAAC
GATCAAATAGGGGAGAAGAA

Downstream 100 bases:

>100_bases
TTTTTCCCCGCCCCCTCCGTGCGTCTGCTATTTTTTCGCCGGCGCCTTCGACTTCTGATGGGCCAGGTCGAACTGGAGCA
TCAGGTAGCCGTAATGGATG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MPKENRLPRILIVDDELAIRRFLCTALDTGEFSLHQAENGHTALAAAVATMPDVILLDLGLPDMDGVEVIRRIREWSQVP
IIVLSVREREDDKVAALDAGADDYLTKPFGVAELVARIRAALRRALQQVPEPIFRSGDLEVDLARRRVTVDGSESQLTPT
EYELLRLLVVHAGKVLTHSQILRQIWGVSHLEQPHVLRVNISNLRRKIEMDPSRPRHILTEPGVGYRLRSDGS

Sequences:

>Translated_233_residues
MPKENRLPRILIVDDELAIRRFLCTALDTGEFSLHQAENGHTALAAAVATMPDVILLDLGLPDMDGVEVIRRIREWSQVP
IIVLSVREREDDKVAALDAGADDYLTKPFGVAELVARIRAALRRALQQVPEPIFRSGDLEVDLARRRVTVDGSESQLTPT
EYELLRLLVVHAGKVLTHSQILRQIWGVSHLEQPHVLRVNISNLRRKIEMDPSRPRHILTEPGVGYRLRSDGS
>Mature_232_residues
PKENRLPRILIVDDELAIRRFLCTALDTGEFSLHQAENGHTALAAAVATMPDVILLDLGLPDMDGVEVIRRIREWSQVPI
IVLSVREREDDKVAALDAGADDYLTKPFGVAELVARIRAALRRALQQVPEPIFRSGDLEVDLARRRVTVDGSESQLTPTE
YELLRLLVVHAGKVLTHSQILRQIWGVSHLEQPHVLRVNISNLRRKIEMDPSRPRHILTEPGVGYRLRSDGS

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=52.4663677130045, Blast_Score=233, Evalue=6e-63,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=37.5565610859729, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=34.2222222222222, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1788394, Length=237, Percent_Identity=33.7552742616034, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=35.2678571428571, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=33.6206896551724, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=37.0535714285714, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=34.2342342342342, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=33.9366515837104, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=31.390134529148, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=28.3261802575107, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI2367329, Length=209, Percent_Identity=34.4497607655502, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=30.4347826086957, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788550, Length=128, Percent_Identity=39.0625, Blast_Score=87, Evalue=6e-19,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=29.2576419213974, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790299, Length=130, Percent_Identity=34.6153846153846, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=29.1666666666667, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26189; Mature: 26057

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKENRLPRILIVDDELAIRRFLCTALDTGEFSLHQAENGHTALAAAVATMPDVILLDLG
CCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHCCCEEEEECC
LPDMDGVEVIRRIREWSQVPIIVLSVREREDDKVAALDAGADDYLTKPFGVAELVARIRA
CCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEECCCCCHHCCCCCCHHHHHHHHHH
ALRRALQQVPEPIFRSGDLEVDLARRRVTVDGSESQLTPTEYELLRLLVVHAGKVLTHSQ
HHHHHHHHCCHHHHHCCCCEEEEEHEEEEECCCCCCCCCHHHHHHHHHHHHHCHHHHHHH
ILRQIWGVSHLEQPHVLRVNISNLRRKIEMDPSRPRHILTEPGVGYRLRSDGS
HHHHHHCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCEEECCCCCCEEECCCCC
>Mature Secondary Structure 
PKENRLPRILIVDDELAIRRFLCTALDTGEFSLHQAENGHTALAAAVATMPDVILLDLG
CCCCCCCEEEEECCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHCCCEEEEECC
LPDMDGVEVIRRIREWSQVPIIVLSVREREDDKVAALDAGADDYLTKPFGVAELVARIRA
CCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEECCCCCHHCCCCCCHHHHHHHHHH
ALRRALQQVPEPIFRSGDLEVDLARRRVTVDGSESQLTPTEYELLRLLVVHAGKVLTHSQ
HHHHHHHHCCHHHHHCCCCEEEEEHEEEEECCCCCCCCCHHHHHHHHHHHHHCHHHHHHH
ILRQIWGVSHLEQPHVLRVNISNLRRKIEMDPSRPRHILTEPGVGYRLRSDGS
HHHHHHCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCEEECCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]