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The map label for this gene is selU [H]

Identifier: 78223587

GI number: 78223587

Start: 2694617

End: 2695654

Strand: Direct

Name: selU [H]

Synonym: Gmet_2384

Alternate gene names: 78223587

Gene position: 2694617-2695654 (Clockwise)

Preceding gene: 78223583

Following gene: 78223589

Centisome position: 67.41

GC content: 60.89

Gene sequence:

>1038_bases
GTGACCAGAACCATTTCATTCCATGAATCACTCCTCGACACCCATCTGGTGGTCGATGCTCGGACCCCCCTCGAATTCGA
GGAGGATCACATCCCCGGCGCCATCAACGTGCCGCTTCTCACCGACGAAGAGCGGGTGGAAATTGGCACCCTCTACAAGC
AGACCGGCCCCCTGGAGGCCAGACGCCGCGGGCTGGAGCTGACCGCGCACCGCTTCCCGGCCATGGTGGAGAAAATCGCC
GCGGCCGCCGCGGGACGTCCCATCCTCGTCTACTGCTGGCGCGGTGGGCTGAGGAGCAAGACCATTACCGCAATCCTCGA
CCTCACCGGCTTCGACGCCGTCCAACTCGTGGGAGGCTACAAGGCGTTCCGCGCCATGGTGACGGAGTATTTCGAGTCCT
TCCACCCACCTGCCCCCCTTGTGGTTCTCCACGGCATGACAGGCGTCGGCAAGACCACCTTTCTCCTCCAACTGGCCGAG
GCGGGCCACTCCGTTATCGACCTGGAAGGACTTGCCTGCCACCGGGGCTCGGCCTTCGGCTCCCTGGGGCTCTCCCAGAA
CCTCTCCCAGAAACGGTTTGAGACGCTTCTCTGGGATGCCTTCCGGAAACTCCCGACCGACAGACCGATCCTCCTGGAGG
GAGAAAGCAAGCGGATCGGCAGGATCAATCTGCCGGGCAACCTCTACGATGTCATGCGGGAGAGTGTGAAGGTCTGGTGC
AATGCATCGGTAGAGACACGGGTGGAGCGCCTCATCGGGGAATATGGACTCCCCGAATATCGCCAGGGGATGTCTGAGGC
ACTGGAACGCATCCGCAAGAAACTGGGGGGAGAAAAGTTCGAAGAGATTTCGGGGTATCTGGAACGGTGGGAGTTGGATC
CCTTCATGGAAGGGCTCATCCGGAACTACTATGACAAGCTCTACTACAAGACGCGGGAATGGACCGAGGACGCAATCGTG
TCACTGGAAGACTTCACCGCCGGACGCCGGGAACTGGAGGAGTTTCTCGATGCCCGGCAGTGGCGGTTAGTGAATTGA

Upstream 100 bases:

>100_bases
CCGGGGGCGTACCGCCCCATCTTCCGTACTACGGGCACTCCGCCCCTTGCCAAAGCTCCGCCTTCCCCCGTATAATAACC
CGCTTTACAAGGAGATTTCC

Downstream 100 bases:

>100_bases
CAGAAGACAGCTACGGGGGTAAGGAACACGCGCGGTTCAGTGCAAAGATCTCCCCGCAAACGTGATAAAGGCCGAAAGGA
GCCCCAGAGCCAGCGCTACG

Product: tRNA 2-selenouridine synthase

Products: NA

Alternate protein names: Selenophosphate-dependent tRNA 2-selenouridine synthase [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MTRTISFHESLLDTHLVVDARTPLEFEEDHIPGAINVPLLTDEERVEIGTLYKQTGPLEARRRGLELTAHRFPAMVEKIA
AAAAGRPILVYCWRGGLRSKTITAILDLTGFDAVQLVGGYKAFRAMVTEYFESFHPPAPLVVLHGMTGVGKTTFLLQLAE
AGHSVIDLEGLACHRGSAFGSLGLSQNLSQKRFETLLWDAFRKLPTDRPILLEGESKRIGRINLPGNLYDVMRESVKVWC
NASVETRVERLIGEYGLPEYRQGMSEALERIRKKLGGEKFEEISGYLERWELDPFMEGLIRNYYDKLYYKTREWTEDAIV
SLEDFTAGRRELEEFLDARQWRLVN

Sequences:

>Translated_345_residues
MTRTISFHESLLDTHLVVDARTPLEFEEDHIPGAINVPLLTDEERVEIGTLYKQTGPLEARRRGLELTAHRFPAMVEKIA
AAAAGRPILVYCWRGGLRSKTITAILDLTGFDAVQLVGGYKAFRAMVTEYFESFHPPAPLVVLHGMTGVGKTTFLLQLAE
AGHSVIDLEGLACHRGSAFGSLGLSQNLSQKRFETLLWDAFRKLPTDRPILLEGESKRIGRINLPGNLYDVMRESVKVWC
NASVETRVERLIGEYGLPEYRQGMSEALERIRKKLGGEKFEEISGYLERWELDPFMEGLIRNYYDKLYYKTREWTEDAIV
SLEDFTAGRRELEEFLDARQWRLVN
>Mature_344_residues
TRTISFHESLLDTHLVVDARTPLEFEEDHIPGAINVPLLTDEERVEIGTLYKQTGPLEARRRGLELTAHRFPAMVEKIAA
AAAGRPILVYCWRGGLRSKTITAILDLTGFDAVQLVGGYKAFRAMVTEYFESFHPPAPLVVLHGMTGVGKTTFLLQLAEA
GHSVIDLEGLACHRGSAFGSLGLSQNLSQKRFETLLWDAFRKLPTDRPILLEGESKRIGRINLPGNLYDVMRESVKVWCN
ASVETRVERLIGEYGLPEYRQGMSEALERIRKKLGGEKFEEISGYLERWELDPFMEGLIRNYYDKLYYKTREWTEDAIVS
LEDFTAGRRELEEFLDARQWRLVN

Specific function: Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA [H]

COG id: COG2603

COG function: function code R; Predicted ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Escherichia coli, GI1786712, Length=357, Percent_Identity=32.7731092436975, Blast_Score=141, Evalue=6e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001763
- InterPro:   IPR017582 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 39283; Mature: 39151

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00380 RHODANESE_1 ; PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTISFHESLLDTHLVVDARTPLEFEEDHIPGAINVPLLTDEERVEIGTLYKQTGPLEA
CCCEEHHHHHHHHHHEEEECCCCCCCCCCCCCCEEECCEECCCCHHHHHHHHHCCCCHHH
RRRGLELTAHRFPAMVEKIAAAAAGRPILVYCWRGGLRSKTITAILDLTGFDAVQLVGGY
HHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHCCCCCHHHHHHHHH
KAFRAMVTEYFESFHPPAPLVVLHGMTGVGKTTFLLQLAEAGHSVIDLEGLACHRGSAFG
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCEECCCCCCC
SLGLSQNLSQKRFETLLWDAFRKLPTDRPILLEGESKRIGRINLPGNLYDVMRESVKVWC
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEECCCHHHHHHHHHHHHHC
NASVETRVERLIGEYGLPEYRQGMSEALERIRKKLGGEKFEEISGYLERWELDPFMEGLI
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHH
RNYYDKLYYKTREWTEDAIVSLEDFTAGRRELEEFLDARQWRLVN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TRTISFHESLLDTHLVVDARTPLEFEEDHIPGAINVPLLTDEERVEIGTLYKQTGPLEA
CCEEHHHHHHHHHHEEEECCCCCCCCCCCCCCEEECCEECCCCHHHHHHHHHCCCCHHH
RRRGLELTAHRFPAMVEKIAAAAAGRPILVYCWRGGLRSKTITAILDLTGFDAVQLVGGY
HHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHCCCCCHHHHHHHHH
KAFRAMVTEYFESFHPPAPLVVLHGMTGVGKTTFLLQLAEAGHSVIDLEGLACHRGSAFG
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCEECCCCCCC
SLGLSQNLSQKRFETLLWDAFRKLPTDRPILLEGESKRIGRINLPGNLYDVMRESVKVWC
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEECCCHHHHHHHHHHHHHC
NASVETRVERLIGEYGLPEYRQGMSEALERIRKKLGGEKFEEISGYLERWELDPFMEGLI
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHH
RNYYDKLYYKTREWTEDAIVSLEDFTAGRRELEEFLDARQWRLVN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA