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The map label for this gene is fba [H]

Identifier: 78223586

GI number: 78223586

Start: 2693036

End: 2694319

Strand: Reverse

Name: fba [H]

Synonym: Gmet_2383

Alternate gene names: 78223586

Gene position: 2694319-2693036 (Counterclockwise)

Preceding gene: 78223588

Following gene: 78223585

Centisome position: 67.4

GC content: 61.06

Gene sequence:

>1284_bases
ATGGCACCGTACTCCGCAGCTTTCGAGAAGGCCCTCCAGGTGGGCCGCCCACCCAACATCCAGAAGCTTTTCCCCAACTC
CAAGGCACTCATCGTGAGCGGCAAGGTGGTGGACCGGGCCATGCTCGTCAAGGGAAAGGCCATAGCCATGGCCGCCAACG
GCCGCAACTACTTCGTGATCCGCGGCGCCCTCATGGCGGCCCAGCGGGCCAACTGCCCCATCATCATCGAAATCGCCAAG
TCGGAAGGTGGCCAGAAGGCATACTGCGCGGTCAACTACTGGAATATGGCCCGCATCGTGGATGCCCTCTGCAACGAACT
CGGCATCACCGTGCCGGTCGCCATTCATGCCGACCACTACGGCATCAAGAACGACAAGGATCTGGCCGCCGCCAAGGTGG
AGATTCCGACCATGTTCGAGGCGGGGATCACCTCCATCGCCATTGATGCCTCCCATCTCCCCGACGACCAGAACCTCCTG
GCCAACCTTGACATCAATCCCTTCATCCCGGCGTGGGCAGGTCTCGAGACCGAGGTGGGGGAGATCAAGGGGAACCAGGG
TCTTTCCACGGTGGACGAGGCGAAGTTCCTGATCCAGGGGCTTAACGCCCATGGAATCCATCCCGACTGGATCGCCCTCA
ACAACGGCACCACCCACGGCCTCGAGGCATCCGCCGCCGGTATCCAGGTGGAGCTCACCGCAGGGATCCACAAGGCTCTG
GAGCCCTACAAGGTGAACGGCGCCCAGCACGGCACCTCTGGCAACAGCTCCGAGCGGCTCCGCGAGATCGCCAATCAGAC
CGCCACCACCAAGGCAAACGTGGCCACCGCCCTGCAGATGATCTCCTGGGGCCTGGAAGTGAACGACTACGGCAATGCCC
AGCTTGACGCCGACGGGAACTTCATCAAGGTAAAGGGTGAGGGGATGACCGAGGAACTCTGGGCCGAGATCGTGGCCTAC
GCTGATTCGAAGGGGTGGAAGAAGGGTGATTACAAGAACCTGAACCTCCCCTTCGAGAACAAGCTCCTGGCCCAGCCGAA
GGATATCCGCGACCGGATGGCCAAGCGGGTCGAGGATTTCGCCTACAAGATGATGACCGAGGTCTTCAACGGGAAAGACA
CCGCACCCCTTGCCATCGAGGCGATCCTCAAGGCTGGTACTTACGATGTCGGGTCGAAGGGTAGCCTCATCGAGGACAAG
TCCCGATGGACCAAGGAGCAGATCGTGGAGCGGGCCAAAACGATTGTGAGCGACAAGGGCCCCGAAGGGAACTTCGAAGA
TTAG

Upstream 100 bases:

>100_bases
GGAAACGTTGATTATTCCTTGCCTTAGTCCCGGTTAACATGCTATAAAATGCCGTTTTTGTCTGCCGAAAAAATTTCACT
AAAACTGAAGGAGGATATGA

Downstream 100 bases:

>100_bases
GCAGTTGTTGACAGGTTGGTGGAGGGGGGGGCGAAGGCCCCCTTTTCCGTATCCGGCGATCGCATGGACGCGAGCCATCG
TCTTGTTGATATCGCAACCA

Product: fructose-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MAPYSAAFEKALQVGRPPNIQKLFPNSKALIVSGKVVDRAMLVKGKAIAMAANGRNYFVIRGALMAAQRANCPIIIEIAK
SEGGQKAYCAVNYWNMARIVDALCNELGITVPVAIHADHYGIKNDKDLAAAKVEIPTMFEAGITSIAIDASHLPDDQNLL
ANLDINPFIPAWAGLETEVGEIKGNQGLSTVDEAKFLIQGLNAHGIHPDWIALNNGTTHGLEASAAGIQVELTAGIHKAL
EPYKVNGAQHGTSGNSSERLREIANQTATTKANVATALQMISWGLEVNDYGNAQLDADGNFIKVKGEGMTEELWAEIVAY
ADSKGWKKGDYKNLNLPFENKLLAQPKDIRDRMAKRVEDFAYKMMTEVFNGKDTAPLAIEAILKAGTYDVGSKGSLIEDK
SRWTKEQIVERAKTIVSDKGPEGNFED

Sequences:

>Translated_427_residues
MAPYSAAFEKALQVGRPPNIQKLFPNSKALIVSGKVVDRAMLVKGKAIAMAANGRNYFVIRGALMAAQRANCPIIIEIAK
SEGGQKAYCAVNYWNMARIVDALCNELGITVPVAIHADHYGIKNDKDLAAAKVEIPTMFEAGITSIAIDASHLPDDQNLL
ANLDINPFIPAWAGLETEVGEIKGNQGLSTVDEAKFLIQGLNAHGIHPDWIALNNGTTHGLEASAAGIQVELTAGIHKAL
EPYKVNGAQHGTSGNSSERLREIANQTATTKANVATALQMISWGLEVNDYGNAQLDADGNFIKVKGEGMTEELWAEIVAY
ADSKGWKKGDYKNLNLPFENKLLAQPKDIRDRMAKRVEDFAYKMMTEVFNGKDTAPLAIEAILKAGTYDVGSKGSLIEDK
SRWTKEQIVERAKTIVSDKGPEGNFED
>Mature_426_residues
APYSAAFEKALQVGRPPNIQKLFPNSKALIVSGKVVDRAMLVKGKAIAMAANGRNYFVIRGALMAAQRANCPIIIEIAKS
EGGQKAYCAVNYWNMARIVDALCNELGITVPVAIHADHYGIKNDKDLAAAKVEIPTMFEAGITSIAIDASHLPDDQNLLA
NLDINPFIPAWAGLETEVGEIKGNQGLSTVDEAKFLIQGLNAHGIHPDWIALNNGTTHGLEASAAGIQVELTAGIHKALE
PYKVNGAQHGTSGNSSERLREIANQTATTKANVATALQMISWGLEVNDYGNAQLDADGNFIKVKGEGMTEELWAEIVAYA
DSKGWKKGDYKNLNLPFENKLLAQPKDIRDRMAKRVEDFAYKMMTEVFNGKDTAPLAIEAILKAGTYDVGSKGSLIEDKS
RWTKEQIVERAKTIVSDKGPEGNFED

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011289
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 46249; Mature: 46118

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPYSAAFEKALQVGRPPNIQKLFPNSKALIVSGKVVDRAMLVKGKAIAMAANGRNYFVI
CCCHHHHHHHHHHCCCCCCHHHHCCCCCEEEEECHHHHHHHEECCCEEEEEECCCEEEEE
RGALMAAQRANCPIIIEIAKSEGGQKAYCAVNYWNMARIVDALCNELGITVPVAIHADHY
EHHHHHHHCCCCCEEEEEECCCCCCEEEEEEEHHHHHHHHHHHHHHCCCEEEEEEECCCC
GIKNDKDLAAAKVEIPTMFEAGITSIAIDASHLPDDQNLLANLDINPFIPAWAGLETEVG
CCCCCCCCEEEEEECCCHHHCCCCEEEEEHHCCCCCCCEEEECCCCCCCCCCCCCCCCHH
EIKGNQGLSTVDEAKFLIQGLNAHGIHPDWIALNNGTTHGLEASAAGIQVELTAGIHKAL
HCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEECCHHHCC
EPYKVNGAQHGTSGNSSERLREIANQTATTKANVATALQMISWGLEVNDYGNAQLDADGN
CCEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEECCCCCEEECCCCC
FIKVKGEGMTEELWAEIVAYADSKGWKKGDYKNLNLPFENKLLAQPKDIRDRMAKRVEDF
EEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AYKMMTEVFNGKDTAPLAIEAILKAGTYDVGSKGSLIEDKSRWTKEQIVERAKTIVSDKG
HHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHCCCC
PEGNFED
CCCCCCC
>Mature Secondary Structure 
APYSAAFEKALQVGRPPNIQKLFPNSKALIVSGKVVDRAMLVKGKAIAMAANGRNYFVI
CCHHHHHHHHHHCCCCCCHHHHCCCCCEEEEECHHHHHHHEECCCEEEEEECCCEEEEE
RGALMAAQRANCPIIIEIAKSEGGQKAYCAVNYWNMARIVDALCNELGITVPVAIHADHY
EHHHHHHHCCCCCEEEEEECCCCCCEEEEEEEHHHHHHHHHHHHHHCCCEEEEEEECCCC
GIKNDKDLAAAKVEIPTMFEAGITSIAIDASHLPDDQNLLANLDINPFIPAWAGLETEVG
CCCCCCCCEEEEEECCCHHHCCCCEEEEEHHCCCCCCCEEEECCCCCCCCCCCCCCCCHH
EIKGNQGLSTVDEAKFLIQGLNAHGIHPDWIALNNGTTHGLEASAAGIQVELTAGIHKAL
HCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEECCHHHCC
EPYKVNGAQHGTSGNSSERLREIANQTATTKANVATALQMISWGLEVNDYGNAQLDADGN
CCEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEECCCCCEEECCCCC
FIKVKGEGMTEELWAEIVAYADSKGWKKGDYKNLNLPFENKLLAQPKDIRDRMAKRVEDF
EEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AYKMMTEVFNGKDTAPLAIEAILKAGTYDVGSKGSLIEDKSRWTKEQIVERAKTIVSDKG
HHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHCCCC
PEGNFED
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]