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The map label for this gene is intZ [H]

Identifier: 78223482

GI number: 78223482

Start: 2583217

End: 2584461

Strand: Direct

Name: intZ [H]

Synonym: Gmet_2279

Alternate gene names: 78223482

Gene position: 2583217-2584461 (Clockwise)

Preceding gene: 78223481

Following gene: 78223483

Centisome position: 64.62

GC content: 49.88

Gene sequence:

>1245_bases
ATGTCAACGCAATTCTCAGACAAGTTCATTCAAAACCTGAAGCCTGAAGCCAAGAAGTATTACATCCGGGAGAGTCGAGG
ATTCGCCATAGTCGTCCACCCTTCCGGTATCAAGAACCCGAAAGGGACAAAGACTTTCCTTTACATCTACACCATCAACG
GCAAGCGCAAGGAGTTGAAGCTAGGGAATTACCCAGAGGTAACGCTCAAGGATGCTCGCATCAAGCACGGCGAAGCCTAT
GCACGTTTGGTTAATGGAGAAGACCCAGTCACCCCTCCAGTCATTAAAGCTGAGCCGCAAGACGAAAACCTCACCTTCGG
TCACTTCACAGAGTTATACCTCCAATGGTCAAAAGATAATCATTCGCCCAAGTGGCACAACACTATCAAGTGCGCCCTGA
ATAAAGATGCACTTCCTGTCTGGGAATATACACTCATAGCTTCCATCAAGCGTCGTGACGCTATAGCCTTTCTTGAAAAC
GTAGCAAGGCGGGGTATCCAAGTAATCAACTTACACAAGGCGACCAGCTCAGTCTTTGACTATGCTTTAGAGCGTGAATA
CATCGAATCAAACCCGATGGCAGGATTAAAAGCAAAGACTATCCCGGCCCTTAAACCAAAAGCGAGAGAGCGCTTTCTCT
CAGACAGTGAGATAAAACACGTCTGGAAGGCCATAGACGAGGGGCCGGGTTATGATGAAACCAAGCGTGCCTTGAAACTC
ATAATGGTAACAGCACAGCGACCGGGGGAGGTTGCAGCAATGCACAGGCGGGAGATTCAAACAGGCGTCGGTAAACCACG
TTGCAAGATATGCAAGCGGTGCGGGTGGTGGACTATTCCGGCAGAAAGGATGAAGAACGGAGAGGAGCACAGGATATACC
TTACCCCTACAGCCCTCGAACTGATCGGAGATGCAGAGGGGTATATCTTTCCGTCACCACAGGACGGGCAACCTATAAAC
AGAAACTCCCTTTCCCAGCTTGTCAGTAGAGAGAGAAACAACAAGAAGCCCAATGGGGAGATGTACCCACCGTATTATGG
ATTGCCTGAGTGGACGCCTCACGATCTGAGACGCACGGCCCGGACCCTTCTGGCTCGTGTTGGCGTACCGGAGGAGCACG
CAGAGGAAGTGCTCAGTCACAAGAAAGAGGGCTTAGTGGACAGGTACAACCGCCATGACTACATGGAGGAGAAGAAGGAG
GCCTTGATTAAACTGGAAGCTGAGTTGATGAAATTGAGCATATAA

Upstream 100 bases:

>100_bases
TTTCCCATAGAGTTATCCAAGCCAAGCCTCGCTTCATACGCTTTACTGCAAGCCCACTAGAGGTTGCTTGCAGGTTGCTT
GTAGCACTCAGAGGGAAATC

Downstream 100 bases:

>100_bases
GCAATGAAATTGCATTGAAAGTGAGGATGATGCCGATGAGAGCTAAGTCGATATTGTTATTTATGGTGATTGCTTTGTAT
CCAACGTTTGTTGCAGCACT

Product: Phage integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MSTQFSDKFIQNLKPEAKKYYIRESRGFAIVVHPSGIKNPKGTKTFLYIYTINGKRKELKLGNYPEVTLKDARIKHGEAY
ARLVNGEDPVTPPVIKAEPQDENLTFGHFTELYLQWSKDNHSPKWHNTIKCALNKDALPVWEYTLIASIKRRDAIAFLEN
VARRGIQVINLHKATSSVFDYALEREYIESNPMAGLKAKTIPALKPKARERFLSDSEIKHVWKAIDEGPGYDETKRALKL
IMVTAQRPGEVAAMHRREIQTGVGKPRCKICKRCGWWTIPAERMKNGEEHRIYLTPTALELIGDAEGYIFPSPQDGQPIN
RNSLSQLVSRERNNKKPNGEMYPPYYGLPEWTPHDLRRTARTLLARVGVPEEHAEEVLSHKKEGLVDRYNRHDYMEEKKE
ALIKLEAELMKLSI

Sequences:

>Translated_414_residues
MSTQFSDKFIQNLKPEAKKYYIRESRGFAIVVHPSGIKNPKGTKTFLYIYTINGKRKELKLGNYPEVTLKDARIKHGEAY
ARLVNGEDPVTPPVIKAEPQDENLTFGHFTELYLQWSKDNHSPKWHNTIKCALNKDALPVWEYTLIASIKRRDAIAFLEN
VARRGIQVINLHKATSSVFDYALEREYIESNPMAGLKAKTIPALKPKARERFLSDSEIKHVWKAIDEGPGYDETKRALKL
IMVTAQRPGEVAAMHRREIQTGVGKPRCKICKRCGWWTIPAERMKNGEEHRIYLTPTALELIGDAEGYIFPSPQDGQPIN
RNSLSQLVSRERNNKKPNGEMYPPYYGLPEWTPHDLRRTARTLLARVGVPEEHAEEVLSHKKEGLVDRYNRHDYMEEKKE
ALIKLEAELMKLSI
>Mature_413_residues
STQFSDKFIQNLKPEAKKYYIRESRGFAIVVHPSGIKNPKGTKTFLYIYTINGKRKELKLGNYPEVTLKDARIKHGEAYA
RLVNGEDPVTPPVIKAEPQDENLTFGHFTELYLQWSKDNHSPKWHNTIKCALNKDALPVWEYTLIASIKRRDAIAFLENV
ARRGIQVINLHKATSSVFDYALEREYIESNPMAGLKAKTIPALKPKARERFLSDSEIKHVWKAIDEGPGYDETKRALKLI
MVTAQRPGEVAAMHRREIQTGVGKPRCKICKRCGWWTIPAERMKNGEEHRIYLTPTALELIGDAEGYIFPSPQDGQPINR
NSLSQLVSRERNNKKPNGEMYPPYYGLPEWTPHDLRRTARTLLARVGVPEEHAEEVLSHKKEGLVDRYNRHDYMEEKKEA
LIKLEAELMKLSI

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=421, Percent_Identity=24.7030878859857, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788974, Length=426, Percent_Identity=23.4741784037559, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 47599; Mature: 47468

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQFSDKFIQNLKPEAKKYYIRESRGFAIVVHPSGIKNPKGTKTFLYIYTINGKRKELK
CCCCHHHHHHHHCCCHHHHHHEEECCCEEEEECCCCCCCCCCCEEEEEEEEECCCCEEEE
LGNYPEVTLKDARIKHGEAYARLVNGEDPVTPPVIKAEPQDENLTFGHFTELYLQWSKDN
CCCCCCEEEECCCCCCCHHHHEEECCCCCCCCCEEECCCCCCCCCHHCEEEEEEEECCCC
HSPKWHNTIKCALNKDALPVWEYTLIASIKRRDAIAFLENVARRGIQVINLHKATSSVFD
CCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHH
YALEREYIESNPMAGLKAKTIPALKPKARERFLSDSEIKHVWKAIDEGPGYDETKRALKL
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHH
IMVTAQRPGEVAAMHRREIQTGVGKPRCKICKRCGWWTIPAERMKNGEEHRIYLTPTALE
HEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHCCCCCCEEEECCHHHH
LIGDAEGYIFPSPQDGQPINRNSLSQLVSRERNNKKPNGEMYPPYYGLPEWTPHDLRRTA
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHH
RTLLARVGVPEEHAEEVLSHKKEGLVDRYNRHDYMEEKKEALIKLEAELMKLSI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STQFSDKFIQNLKPEAKKYYIRESRGFAIVVHPSGIKNPKGTKTFLYIYTINGKRKELK
CCCHHHHHHHHCCCHHHHHHEEECCCEEEEECCCCCCCCCCCEEEEEEEEECCCCEEEE
LGNYPEVTLKDARIKHGEAYARLVNGEDPVTPPVIKAEPQDENLTFGHFTELYLQWSKDN
CCCCCCEEEECCCCCCCHHHHEEECCCCCCCCCEEECCCCCCCCCHHCEEEEEEEECCCC
HSPKWHNTIKCALNKDALPVWEYTLIASIKRRDAIAFLENVARRGIQVINLHKATSSVFD
CCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHH
YALEREYIESNPMAGLKAKTIPALKPKARERFLSDSEIKHVWKAIDEGPGYDETKRALKL
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHH
IMVTAQRPGEVAAMHRREIQTGVGKPRCKICKRCGWWTIPAERMKNGEEHRIYLTPTALE
HEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHCCCCCCEEEECCHHHH
LIGDAEGYIFPSPQDGQPINRNSLSQLVSRERNNKKPNGEMYPPYYGLPEWTPHDLRRTA
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHH
RTLLARVGVPEEHAEEVLSHKKEGLVDRYNRHDYMEEKKEALIKLEAELMKLSI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]