Click here to switch to the map view.

The map label for this gene is yoaE [H]

Identifier: 78223432

GI number: 78223432

Start: 2519197

End: 2521872

Strand: Reverse

Name: yoaE [H]

Synonym: Gmet_2227

Alternate gene names: 78223432

Gene position: 2521872-2519197 (Counterclockwise)

Preceding gene: 78223433

Following gene: 78223428

Centisome position: 63.09

GC content: 57.66

Gene sequence:

>2676_bases
ATGACTGAAAGTAACAGTTGTACAAAGCGCACTTTCTGTACAATTTGCCCGCAACATTGCGGTGTTCTCGTTACCGTGAA
GGACGGACGACCCGTTGCTGTAAAGGGTGATCCCACGAGCCCCATCGGCAGTGGGAGCTTGTGTGTCAAGGGGCCACGTG
TCCTCGATCTTCATGAACATCCGGGCCGCCTCAATTATCCACTTAAGCGGATCGGGGCGCGTGGCGAGATGAAATGGGAA
CAGATCAGTTGGGAGCAGGCTCTGGACGAGATCGCGGCAAAGTTGTCATCTCTGCGCGACCAGTTCGGACCCGAAATGCT
GGCCACCCTCGGTGGTACCCACAAGGGGCCGGGCGATTGGTCCTCCTGGCGGTTCTGCAACCTGTTCGGTACTCCCAATT
TCGTTAACCAGGGGCGTAACTGCGGGGTAGGGCATATTCTCGCCGAGAGTTCGGTTTATGGTTATGACACGATGTATGCG
GCTGTCCATCCGGGTAAGACCATGCTTGCCTTGATCTGGGGGTCTAATCCCGCGGAATCAGGTACTACGGTGATGGAACG
GCTTATCCAGGGAAAGAAGCAAGGAATGAAAATAGTGGTCGTTGATCCGCGCAAGACCCGTGTGGCGGAAATTGCCGATA
TATGGGTACCGGTCCGGCCACGCACTGACGGGGCCCTGGCTCTGGGTATCGCCCATGTCATGCTTCGTGAAGGGCTCTAT
GATCGGGAGTTTGTTGCTGCATATTGCCAAGGGTTTGATGAGGCCCGGGAAGTGATTGAGCAGTATCCGCCGGAGCGGGT
CGCTGCAATCTGCGGAATTCCGGTTGAGATGATCGAGGAGGTGGCCCGTTTGTACGGCACAGTGCGTCCTGCCCGTCTTG
TGCCCGGAGTAGCATTGGTGCAGGCTGGTCAAGGTGCCAGTCGTACAGCCACCCTTGTGCGGGCGATTCTTGTTGCAATC
TCCGGCAATCTCGATGTGCTGGGAGGCGACCCCCTGGCCATGAAATACGATGAGGGACAGTTCGCCTGGCTGGACAACAT
TCATTGGGATGCCCTGGTGCATCACCCCCTGCGCACACGGGATACCCTTGGCTCCGCCGAGTTCCCCATTATCGGCGTCG
AGGCATACAAACGCTTCCGCGAAACCCAGGCCCGTCTCCACCCCAAGGGGCACAACGCGGCCGCCTACATGCTGTTTGCC
AACCAGAACGCCATCTATCGCGCTGTACTTGCAGAAGAGCCCTATCCGGTAAAGGCCGTCATCGTCCAGAACGGAGAGCC
GCTCCTCTCCATGGGGGGAGCACGGGCTGCCCATGATGCGTTCACGAGCCCCAATCTTGATCTGCTGGTGACTATGGATC
TGTTCATGACCCCTACAGCCCAGCTGTCTGATTATGTTCTCCCCGCGGCCCACTATCTGGAACGGCCTGACATCAGCATG
CACTGGGGGTTGACCCACCTCTTCGTGTGCGGGGAGCAGGCGGTGGAGCCTCTCTTTGAGCGGCGCAACGATTATGAACT
CTGGAAAGGACTTGGCAAGAGGCTGGGACAGGAAGACCGATGGCCGGCAGACCTGGAAGGGATGCTCAACCTGTTCCTCG
CTCCGTCGGGGCGTTCCTTTGCCCAGTGGACCAAAGAGGAGCGGAATTACCAGGCTCCCCGTCTCATGCACAAAAAACAC
GAACAACAGGGGTTTGCCACCCCGTCGGGAAAGGTAGAGCTGTTACCGACCATGTTTGAAAGGGCAGGTATTGAAGCTCT
CCCTGTCTACGAGGGGCCACCCTACAGCACGCCGGAAGTGGACGACCCGGCCCTTTACCCCTATCACATGATAGCAGGGA
ATCGTACCCGCTATTTCATGGGGTCCAACCTCCATCAGATCGAGGCCCTGCGCAAGCATTGTCCCGATCCACCCGTCTGG
ATTCATCCTGAGACAGCAGCCCGTCATGGTATCAATGATGGAGAGTGGGTGATCATCGAACGTCCTGAAGGGCGCATCCG
TCAGAAGGCTCTCCTGACCGACAAAATCCGACCTGATACGGTTCAACCTGAGGGGTATTGGTGGTACCCGGAGCGGGAGC
CGGGAGAGCCCGGGTTGTCAGGTCTCTGGGAGGCCAATGCAAATGCAATTACTCCTACCGACATCGGCTTGTGCAGTTTT
GCCGGAGACCAGCCACTGCGTGGTGGACGCTGCCGGATCGCTCCTGCAGGCCATCCCGCCCTGGGCAGGGCCGACATCCT
GGCCGGACTTCAGGCCCTGGCTGACGATCTGGAGCGGTTAGTGGGGCATCTCGATTCCGGATTTTTAGAACGTCTCGGCA
GCGACAGTCGTTTCGCTTTATGGAGCAGCCTTGTAGAGATATCCCGGACTGGTGCTCAGAGTCGGGAGTGGCTACGGAAC
GTGTCGGGCGTTATGGTAGCTGACGGAAACGTCGCTACGTTCAGGCCGGAGGAAACCTTGGCGGTTCAATTGCTGGATAA
GCTGATAGATGATAAACGGGCATTGTGTCAGGAAATGCTTCAGCTTGTTGCAGGGCTTTCGCAGGAGTCGTTGGCTCAGT
GCTGCCGGCATCCGGATCTGGGGGAGGGAACTGTGGAATCGCTGCTTTGGAGCCATATGCGTCACGAAGCAAATCAGAGT
GAAAAAATTCGTCAGCTGCTTACTGGCATGCGGTGA

Upstream 100 bases:

>100_bases
CCGTTGCCTTGCCCAAAATATATAATCGCGCAATTCCTTCTACTGAATGATGCCGGCCTGTGGTACGAGAAGTAACTACC
CCAAAGAAAGAGGCCTAATA

Downstream 100 bases:

>100_bases
ACAAAGGCGGGATTGGCAACTGGGGGAGTGGCATGCTCCCCATCCAGTTGCCAATTGTTTTTAATTAGGTTCCGGTTTCT
CTTGGAGGTAGACGCCGCAG

Product: molybdopterin oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 891; Mature: 890

Protein sequence:

>891_residues
MTESNSCTKRTFCTICPQHCGVLVTVKDGRPVAVKGDPTSPIGSGSLCVKGPRVLDLHEHPGRLNYPLKRIGARGEMKWE
QISWEQALDEIAAKLSSLRDQFGPEMLATLGGTHKGPGDWSSWRFCNLFGTPNFVNQGRNCGVGHILAESSVYGYDTMYA
AVHPGKTMLALIWGSNPAESGTTVMERLIQGKKQGMKIVVVDPRKTRVAEIADIWVPVRPRTDGALALGIAHVMLREGLY
DREFVAAYCQGFDEAREVIEQYPPERVAAICGIPVEMIEEVARLYGTVRPARLVPGVALVQAGQGASRTATLVRAILVAI
SGNLDVLGGDPLAMKYDEGQFAWLDNIHWDALVHHPLRTRDTLGSAEFPIIGVEAYKRFRETQARLHPKGHNAAAYMLFA
NQNAIYRAVLAEEPYPVKAVIVQNGEPLLSMGGARAAHDAFTSPNLDLLVTMDLFMTPTAQLSDYVLPAAHYLERPDISM
HWGLTHLFVCGEQAVEPLFERRNDYELWKGLGKRLGQEDRWPADLEGMLNLFLAPSGRSFAQWTKEERNYQAPRLMHKKH
EQQGFATPSGKVELLPTMFERAGIEALPVYEGPPYSTPEVDDPALYPYHMIAGNRTRYFMGSNLHQIEALRKHCPDPPVW
IHPETAARHGINDGEWVIIERPEGRIRQKALLTDKIRPDTVQPEGYWWYPEREPGEPGLSGLWEANANAITPTDIGLCSF
AGDQPLRGGRCRIAPAGHPALGRADILAGLQALADDLERLVGHLDSGFLERLGSDSRFALWSSLVEISRTGAQSREWLRN
VSGVMVADGNVATFRPEETLAVQLLDKLIDDKRALCQEMLQLVAGLSQESLAQCCRHPDLGEGTVESLLWSHMRHEANQS
EKIRQLLTGMR

Sequences:

>Translated_891_residues
MTESNSCTKRTFCTICPQHCGVLVTVKDGRPVAVKGDPTSPIGSGSLCVKGPRVLDLHEHPGRLNYPLKRIGARGEMKWE
QISWEQALDEIAAKLSSLRDQFGPEMLATLGGTHKGPGDWSSWRFCNLFGTPNFVNQGRNCGVGHILAESSVYGYDTMYA
AVHPGKTMLALIWGSNPAESGTTVMERLIQGKKQGMKIVVVDPRKTRVAEIADIWVPVRPRTDGALALGIAHVMLREGLY
DREFVAAYCQGFDEAREVIEQYPPERVAAICGIPVEMIEEVARLYGTVRPARLVPGVALVQAGQGASRTATLVRAILVAI
SGNLDVLGGDPLAMKYDEGQFAWLDNIHWDALVHHPLRTRDTLGSAEFPIIGVEAYKRFRETQARLHPKGHNAAAYMLFA
NQNAIYRAVLAEEPYPVKAVIVQNGEPLLSMGGARAAHDAFTSPNLDLLVTMDLFMTPTAQLSDYVLPAAHYLERPDISM
HWGLTHLFVCGEQAVEPLFERRNDYELWKGLGKRLGQEDRWPADLEGMLNLFLAPSGRSFAQWTKEERNYQAPRLMHKKH
EQQGFATPSGKVELLPTMFERAGIEALPVYEGPPYSTPEVDDPALYPYHMIAGNRTRYFMGSNLHQIEALRKHCPDPPVW
IHPETAARHGINDGEWVIIERPEGRIRQKALLTDKIRPDTVQPEGYWWYPEREPGEPGLSGLWEANANAITPTDIGLCSF
AGDQPLRGGRCRIAPAGHPALGRADILAGLQALADDLERLVGHLDSGFLERLGSDSRFALWSSLVEISRTGAQSREWLRN
VSGVMVADGNVATFRPEETLAVQLLDKLIDDKRALCQEMLQLVAGLSQESLAQCCRHPDLGEGTVESLLWSHMRHEANQS
EKIRQLLTGMR
>Mature_890_residues
TESNSCTKRTFCTICPQHCGVLVTVKDGRPVAVKGDPTSPIGSGSLCVKGPRVLDLHEHPGRLNYPLKRIGARGEMKWEQ
ISWEQALDEIAAKLSSLRDQFGPEMLATLGGTHKGPGDWSSWRFCNLFGTPNFVNQGRNCGVGHILAESSVYGYDTMYAA
VHPGKTMLALIWGSNPAESGTTVMERLIQGKKQGMKIVVVDPRKTRVAEIADIWVPVRPRTDGALALGIAHVMLREGLYD
REFVAAYCQGFDEAREVIEQYPPERVAAICGIPVEMIEEVARLYGTVRPARLVPGVALVQAGQGASRTATLVRAILVAIS
GNLDVLGGDPLAMKYDEGQFAWLDNIHWDALVHHPLRTRDTLGSAEFPIIGVEAYKRFRETQARLHPKGHNAAAYMLFAN
QNAIYRAVLAEEPYPVKAVIVQNGEPLLSMGGARAAHDAFTSPNLDLLVTMDLFMTPTAQLSDYVLPAAHYLERPDISMH
WGLTHLFVCGEQAVEPLFERRNDYELWKGLGKRLGQEDRWPADLEGMLNLFLAPSGRSFAQWTKEERNYQAPRLMHKKHE
QQGFATPSGKVELLPTMFERAGIEALPVYEGPPYSTPEVDDPALYPYHMIAGNRTRYFMGSNLHQIEALRKHCPDPPVWI
HPETAARHGINDGEWVIIERPEGRIRQKALLTDKIRPDTVQPEGYWWYPEREPGEPGLSGLWEANANAITPTDIGLCSFA
GDQPLRGGRCRIAPAGHPALGRADILAGLQALADDLERLVGHLDSGFLERLGSDSRFALWSSLVEISRTGAQSREWLRNV
SGVMVADGNVATFRPEETLAVQLLDKLIDDKRALCQEMLQLVAGLSQESLAQCCRHPDLGEGTVESLLWSHMRHEANQSE
KIRQLLTGMR

Specific function: Terminal Reductase During Anaerobic Growth On Various Sulfoxide And N-Oxide Compounds (By Similarity). [C]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm Face Of The Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI171474008, Length=759, Percent_Identity=26.2187088274045, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI87081797, Length=764, Percent_Identity=25.9162303664921, Blast_Score=183, Evalue=5e-47,
Organism=Escherichia coli, GI1787870, Length=753, Percent_Identity=26.0292164674635, Blast_Score=180, Evalue=5e-46,
Organism=Escherichia coli, GI3868721, Length=715, Percent_Identity=25.3146853146853, Blast_Score=177, Evalue=3e-45,
Organism=Escherichia coli, GI87081994, Length=754, Percent_Identity=24.6684350132626, Blast_Score=133, Evalue=5e-32,
Organism=Escherichia coli, GI3868720, Length=406, Percent_Identity=24.384236453202, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1788534, Length=320, Percent_Identity=22.8125, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI3868719, Length=406, Percent_Identity=23.8916256157635, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1787231, Length=355, Percent_Identity=25.6338028169014, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.8.99.- [C]

Molecular weight: Translated: 98790; Mature: 98659

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTESNSCTKRTFCTICPQHCGVLVTVKDGRPVAVKGDPTSPIGSGSLCVKGPRVLDLHEH
CCCCCCCCHHHHHHCCHHHCCEEEEECCCCEEEEECCCCCCCCCCCEEECCCEEEECCCC
PGRLNYPLKRIGARGEMKWEQISWEQALDEIAAKLSSLRDQFGPEMLATLGGTHKGPGDW
CCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCC
SSWRFCNLFGTPNFVNQGRNCGVGHILAESSVYGYDTMYAAVHPGKTMLALIWGSNPAES
CCCEEEEECCCCHHHHCCCCCCCHHEEECCCCCCCCEEEEEECCCCEEEEEEECCCCCCC
GTTVMERLIQGKKQGMKIVVVDPRKTRVAEIADIWVPVRPRTDGALALGIAHVMLREGLY
HHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHCCCC
DREFVAAYCQGFDEAREVIEQYPPERVAAICGIPVEMIEEVARLYGTVRPARLVPGVALV
CHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHCCCHHEE
QAGQGASRTATLVRAILVAISGNLDVLGGDPLAMKYDEGQFAWLDNIHWDALVHHPLRTR
ECCCCCHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCEEEECCCCHHHHHCCCCHHH
DTLGSAEFPIIGVEAYKRFRETQARLHPKGHNAAAYMLFANQNAIYRAVLAEEPYPVKAV
HCCCCCCCCEEEHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEECCCCCCEEEE
IVQNGEPLLSMGGARAAHDAFTSPNLDLLVTMDLFMTPTAQLSDYVLPAAHYLERPDISM
EEECCCCHHHCCCCHHHHHCCCCCCCEEEEEEHHHHCCCHHHHHHHHHHHHHHCCCCCEE
HWGLTHLFVCGEQAVEPLFERRNDYELWKGLGKRLGQEDRWPADLEGMLNLFLAPSGRSF
ECCHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCHH
AQWTKEERNYQAPRLMHKKHEQQGFATPSGKVELLPTMFERAGIEALPVYEGPPYSTPEV
HHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEHHHHHHHHCCCCEEECCCCCCCCCCCC
DDPALYPYHMIAGNRTRYFMGSNLHQIEALRKHCPDPPVWIHPETAARHGINDGEWVIIE
CCCCCCCEEEECCCCEEEECCCCHHHHHHHHHHCCCCCEEECCCHHHHCCCCCCCEEEEE
RPEGRIRQKALLTDKIRPDTVQPEGYWWYPEREPGEPGLSGLWEANANAITPTDIGLCSF
CCCCHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCHHCCCCCCCCCCCCCCEEC
AGDQPLRGGRCRIAPAGHPALGRADILAGLQALADDLERLVGHLDSGFLERLGSDSRFAL
CCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHH
WSSLVEISRTGAQSREWLRNVSGVMVADGNVATFRPEETLAVQLLDKLIDDKRALCQEML
HHHHHHHHHCCHHHHHHHHCCCCEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
QLVAGLSQESLAQCCRHPDLGEGTVESLLWSHMRHEANQSEKIRQLLTGMR
HHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TESNSCTKRTFCTICPQHCGVLVTVKDGRPVAVKGDPTSPIGSGSLCVKGPRVLDLHEH
CCCCCCCHHHHHHCCHHHCCEEEEECCCCEEEEECCCCCCCCCCCEEECCCEEEECCCC
PGRLNYPLKRIGARGEMKWEQISWEQALDEIAAKLSSLRDQFGPEMLATLGGTHKGPGDW
CCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCC
SSWRFCNLFGTPNFVNQGRNCGVGHILAESSVYGYDTMYAAVHPGKTMLALIWGSNPAES
CCCEEEEECCCCHHHHCCCCCCCHHEEECCCCCCCCEEEEEECCCCEEEEEEECCCCCCC
GTTVMERLIQGKKQGMKIVVVDPRKTRVAEIADIWVPVRPRTDGALALGIAHVMLREGLY
HHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHCCCC
DREFVAAYCQGFDEAREVIEQYPPERVAAICGIPVEMIEEVARLYGTVRPARLVPGVALV
CHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHCCCHHEE
QAGQGASRTATLVRAILVAISGNLDVLGGDPLAMKYDEGQFAWLDNIHWDALVHHPLRTR
ECCCCCHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCEEEECCCCHHHHHCCCCHHH
DTLGSAEFPIIGVEAYKRFRETQARLHPKGHNAAAYMLFANQNAIYRAVLAEEPYPVKAV
HCCCCCCCCEEEHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEECCCCCCEEEE
IVQNGEPLLSMGGARAAHDAFTSPNLDLLVTMDLFMTPTAQLSDYVLPAAHYLERPDISM
EEECCCCHHHCCCCHHHHHCCCCCCCEEEEEEHHHHCCCHHHHHHHHHHHHHHCCCCCEE
HWGLTHLFVCGEQAVEPLFERRNDYELWKGLGKRLGQEDRWPADLEGMLNLFLAPSGRSF
ECCHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCHH
AQWTKEERNYQAPRLMHKKHEQQGFATPSGKVELLPTMFERAGIEALPVYEGPPYSTPEV
HHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEHHHHHHHHCCCCEEECCCCCCCCCCCC
DDPALYPYHMIAGNRTRYFMGSNLHQIEALRKHCPDPPVWIHPETAARHGINDGEWVIIE
CCCCCCCEEEECCCCEEEECCCCHHHHHHHHHHCCCCCEEECCCHHHHCCCCCCCEEEEE
RPEGRIRQKALLTDKIRPDTVQPEGYWWYPEREPGEPGLSGLWEANANAITPTDIGLCSF
CCCCHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCHHCCCCCCCCCCCCCCEEC
AGDQPLRGGRCRIAPAGHPALGRADILAGLQALADDLERLVGHLDSGFLERLGSDSRFAL
CCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHH
WSSLVEISRTGAQSREWLRNVSGVMVADGNVATFRPEETLAVQLLDKLIDDKRALCQEML
HHHHHHHHHCCHHHHHHHHCCCCEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
QLVAGLSQESLAQCCRHPDLGEGTVESLLWSHMRHEANQSEKIRQLLTGMR
HHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: May Bind 4Fe-4S Cluster. [C]

Metal ions: Fe; Mo [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]