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The map label for this gene is crt [H]

Identifier: 78223400

GI number: 78223400

Start: 2482698

End: 2483471

Strand: Reverse

Name: crt [H]

Synonym: Gmet_2195

Alternate gene names: 78223400

Gene position: 2483471-2482698 (Counterclockwise)

Preceding gene: 78223401

Following gene: 78223399

Centisome position: 62.13

GC content: 57.36

Gene sequence:

>774_bases
ATGACCGAAAAATTCGAAACGATTATCTTCGAAAAGCGCGGAGCCATTGCAGTTATTACCATGAACCGCCCTGACAAGCT
CAATGCCTGCAACACGGTCATGTACCGGGAGCTTGATTGTGTCCTTGACAAGATAGAGTCGGACCGGGAAGTGCAGGCGG
TGGTCATCACCGGTTCGGGCGACAAGGCGTTCAGCGCCGGAGCCGATCTGGAGGAGCTGAATTTCGATAACCTGCGCGAC
TCGTCAGAGTATATCAAGGTTGACGCCAGGGCCTTCCGGCGGCTGGAAAATATCCCCCAGCCGGTTATTGCCGCGGTAAA
CGGGGCCGCCATCGGTTACGGCTGCAAGGTGGCGATCGTGAGTGATATTGCCATCGCTTCGGAAACGGCAAAATTCTCAC
TGCCTGGCGCTACCTTCGGCGCCGTGCACGTCATAATGCTCGGCAGGGCGCGGGAGGTCATGGGGAGGAAGCGGCTATCC
CAACTCCTCCTGACAGGGGAGAAGATCGATGCCCACGAGGCGGAGAGATACGGGATCGTCAACAAGGTCGTTCCCCAGGA
CCAGGTGATGGCAGAGGCCATGAAGATAGCGAACAGGATTGCGGAGTGCCCGCCGCTCTCGGTCCAGGTGACCAGGCGCA
TGCTGCATCGCGGCATGGATGATGATTACCGGTGGGAGGATCTGCTGAGCCCCGGGTTGTTGCTCATGGAGGATGTCAAG
GAAGGGCGCCGGGCATTCAAAGAGAAACGGAAACCGAAATTTGTTGGTAAATGA

Upstream 100 bases:

>100_bases
CGCTATTTTACGGATCTGCTGTTTCGAACAGCTGCCGGTTAACGCGGAATGCCGGTGTGGCAAAAACTGAAATCAATCTG
GATTCCCTGAGGAGAGAACC

Downstream 100 bases:

>100_bases
GAATGATAAATGCATACAGAGGAGGGAAATCCCATGGGCTTGGAACGTTTCAGTCTGAAAGGTAAAACCGCTATCGTCAC
CGGTGCCAGTCAGGGGCTGG

Product: short chain enoyl-CoA hydratase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MTEKFETIIFEKRGAIAVITMNRPDKLNACNTVMYRELDCVLDKIESDREVQAVVITGSGDKAFSAGADLEELNFDNLRD
SSEYIKVDARAFRRLENIPQPVIAAVNGAAIGYGCKVAIVSDIAIASETAKFSLPGATFGAVHVIMLGRAREVMGRKRLS
QLLLTGEKIDAHEAERYGIVNKVVPQDQVMAEAMKIANRIAECPPLSVQVTRRMLHRGMDDDYRWEDLLSPGLLLMEDVK
EGRRAFKEKRKPKFVGK

Sequences:

>Translated_257_residues
MTEKFETIIFEKRGAIAVITMNRPDKLNACNTVMYRELDCVLDKIESDREVQAVVITGSGDKAFSAGADLEELNFDNLRD
SSEYIKVDARAFRRLENIPQPVIAAVNGAAIGYGCKVAIVSDIAIASETAKFSLPGATFGAVHVIMLGRAREVMGRKRLS
QLLLTGEKIDAHEAERYGIVNKVVPQDQVMAEAMKIANRIAECPPLSVQVTRRMLHRGMDDDYRWEDLLSPGLLLMEDVK
EGRRAFKEKRKPKFVGK
>Mature_256_residues
TEKFETIIFEKRGAIAVITMNRPDKLNACNTVMYRELDCVLDKIESDREVQAVVITGSGDKAFSAGADLEELNFDNLRDS
SEYIKVDARAFRRLENIPQPVIAAVNGAAIGYGCKVAIVSDIAIASETAKFSLPGATFGAVHVIMLGRAREVMGRKRLSQ
LLLTGEKIDAHEAERYGIVNKVVPQDQVMAEAMKIANRIAECPPLSVQVTRRMLHRGMDDDYRWEDLLSPGLLLMEDVKE
GRRAFKEKRKPKFVGK

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=263, Percent_Identity=36.5019011406844, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI31542718, Length=244, Percent_Identity=30.7377049180328, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI70995211, Length=208, Percent_Identity=35.5769230769231, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI45643119, Length=220, Percent_Identity=29.0909090909091, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI260275230, Length=220, Percent_Identity=29.0909090909091, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI260274832, Length=220, Percent_Identity=29.0909090909091, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI37594471, Length=192, Percent_Identity=28.125, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI37594469, Length=192, Percent_Identity=28.125, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI68989263, Length=234, Percent_Identity=31.1965811965812, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI4502327, Length=263, Percent_Identity=26.615969581749, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI221136756, Length=229, Percent_Identity=26.2008733624454, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI221136753, Length=229, Percent_Identity=26.2008733624454, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI221307494, Length=229, Percent_Identity=26.2008733624454, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI62530384, Length=205, Percent_Identity=26.8292682926829, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI20127408, Length=183, Percent_Identity=27.3224043715847, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI150378541, Length=257, Percent_Identity=28.0155642023346, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI295842266, Length=202, Percent_Identity=25.2475247524752, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787659, Length=259, Percent_Identity=32.4324324324324, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI221142681, Length=261, Percent_Identity=31.4176245210728, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1788597, Length=263, Percent_Identity=28.5171102661597, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87082183, Length=250, Percent_Identity=29.6, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787660, Length=269, Percent_Identity=29.368029739777, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790281, Length=187, Percent_Identity=26.7379679144385, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788682, Length=193, Percent_Identity=23.8341968911917, Blast_Score=64, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17554946, Length=263, Percent_Identity=35.7414448669202, Blast_Score=143, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI25145438, Length=261, Percent_Identity=35.632183908046, Blast_Score=137, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17549921, Length=215, Percent_Identity=31.1627906976744, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17540714, Length=216, Percent_Identity=29.1666666666667, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17540306, Length=237, Percent_Identity=31.6455696202532, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17536985, Length=270, Percent_Identity=28.1481481481481, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17535521, Length=228, Percent_Identity=28.9473684210526, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17534483, Length=215, Percent_Identity=27.906976744186, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560910, Length=245, Percent_Identity=28.1632653061224, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI25144276, Length=187, Percent_Identity=29.9465240641711, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17508953, Length=187, Percent_Identity=29.9465240641711, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17508951, Length=187, Percent_Identity=29.9465240641711, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17558304, Length=183, Percent_Identity=27.8688524590164, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25144157, Length=195, Percent_Identity=27.6923076923077, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25144160, Length=195, Percent_Identity=27.6923076923077, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI20129971, Length=247, Percent_Identity=35.6275303643725, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24653477, Length=247, Percent_Identity=35.6275303643725, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24653139, Length=261, Percent_Identity=31.0344827586207, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI19920382, Length=230, Percent_Identity=30.4347826086957, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24654903, Length=260, Percent_Identity=26.5384615384615, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI19922422, Length=259, Percent_Identity=27.027027027027, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21357171, Length=262, Percent_Identity=25.5725190839695, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24650670, Length=264, Percent_Identity=23.4848484848485, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 28644; Mature: 28512

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEKFETIIFEKRGAIAVITMNRPDKLNACNTVMYRELDCVLDKIESDREVQAVVITGSG
CCCHHHHHEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
DKAFSAGADLEELNFDNLRDSSEYIKVDARAFRRLENIPQPVIAAVNGAAIGYGCKVAIV
CCCCCCCCCHHHCCCCCCCCCCHHEEHHHHHHHHHHCCCHHHHHHHCCCEECCCCEEEEE
SDIAIASETAKFSLPGATFGAVHVIMLGRAREVMGRKRLSQLLLTGEKIDAHEAERYGIV
HHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCHH
NKVVPQDQVMAEAMKIANRIAECPPLSVQVTRRMLHRGMDDDYRWEDLLSPGLLLMEDVK
HHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHH
EGRRAFKEKRKPKFVGK
HHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TEKFETIIFEKRGAIAVITMNRPDKLNACNTVMYRELDCVLDKIESDREVQAVVITGSG
CCHHHHHEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
DKAFSAGADLEELNFDNLRDSSEYIKVDARAFRRLENIPQPVIAAVNGAAIGYGCKVAIV
CCCCCCCCCHHHCCCCCCCCCCHHEEHHHHHHHHHHCCCHHHHHHHCCCEECCCCEEEEE
SDIAIASETAKFSLPGATFGAVHVIMLGRAREVMGRKRLSQLLLTGEKIDAHEAERYGIV
HHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCHH
NKVVPQDQVMAEAMKIANRIAECPPLSVQVTRRMLHRGMDDDYRWEDLLSPGLLLMEDVK
HHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHH
EGRRAFKEKRKPKFVGK
HHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]