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The map label for this gene is cutM [H]

Identifier: 78223341

GI number: 78223341

Start: 2400707

End: 2401576

Strand: Direct

Name: cutM [H]

Synonym: Gmet_2134

Alternate gene names: 78223341

Gene position: 2400707-2401576 (Clockwise)

Preceding gene: 78223340

Following gene: 78223342

Centisome position: 60.06

GC content: 62.64

Gene sequence:

>870_bases
ATGTACATGCCCGATTTTGAGTACCATACTCCGGAGACTCTGACCGAGGCCTGCGCGCTCCTGGACGAACTGGGAGAACA
GGCCACGGTCCTGGCCGGGGGAACCGATGTCCTCCACAAGATGAAGGTGGGTAAACTGGCGCCGGGGCATCTGGTATCGC
TCAAAAACCTGGACGACCTTCGCACCATCAGCCACGAGCCGGGGCGCGGCATCGTCATGGGAGCCCTGACCAGCCACAAT
GCCATCTACACCTCGCGTCTGCTCCAGAAACGCTACCTGTCCCTCCCCATGGCGGCCCACACCATGGCCTCCAACCAGAT
CTGCAACATGGGAACCGTGGGCGGTAACATCGTCAACGGCGTCCCTTCCGCCGACCTCCCTCCGATCCTCATTGCCCTCA
ACGCCTCGATACGGCTGGTTTCCAGCAAAGGGGAGCGAACCATGCCCCTGGAAGACTTCTTCCATGGCTCGGCCGAGACG
GTGATCGCTCCGGGCGAGTTGCTGGCCGACATCACCATCCCGGACCAGCCGACCACCGGGAGCACCTACATGAAATTCGG
CCTGCGCCGCTCCGGTGCTCTAGCGGTTGTTGGGGTAGCGGTGTCGGTTACGGTGAAAGGTGACATCCTGGAAGACGTCC
GGATCGTTCTCGCTTCGGCGGCGCCAACGGTAATGCGCGCTCGGAAGGCAGAGGACCGGCTGAGGGGGAAAAAGATCAGC
GACGAATTGCTGGCCGAAGCCGGGGAGGAGGCAGCGGCGGAAAGCCGTCCCCGGGACAGCATCCGGGGTTCCGCCGAATA
TCGCCGGAACTTGGTCGGAGTGCTCACCAAACGGGCGCTGCGCAAAGCAATCGACGAAGGCCACTCGTAA

Upstream 100 bases:

>100_bases
GGGATTTCCGGGAATAAGAATGATTTTCTTTTAACCTAACACCTTGCATACAAGATATCCGCATAGGGCAAGGACCATCA
TCAATGTGAGGAGATACACC

Downstream 100 bases:

>100_bases
GGAGGTAAATATATGTTGCAGTCAATAACCGACAAAGACGGAGTGAAGCGTTACCTGATCACCCTGAAGGTGAATGGGGA
TGCGAAGACCGTGCTGGTAA

Product: molybdopterin dehydrogenase, FAD-binding:CO dehydrogenase flavoprotein-like

Products: NA

Alternate protein names: CO dehydrogenase subunit M; CO-DH M [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MYMPDFEYHTPETLTEACALLDELGEQATVLAGGTDVLHKMKVGKLAPGHLVSLKNLDDLRTISHEPGRGIVMGALTSHN
AIYTSRLLQKRYLSLPMAAHTMASNQICNMGTVGGNIVNGVPSADLPPILIALNASIRLVSSKGERTMPLEDFFHGSAET
VIAPGELLADITIPDQPTTGSTYMKFGLRRSGALAVVGVAVSVTVKGDILEDVRIVLASAAPTVMRARKAEDRLRGKKIS
DELLAEAGEEAAAESRPRDSIRGSAEYRRNLVGVLTKRALRKAIDEGHS

Sequences:

>Translated_289_residues
MYMPDFEYHTPETLTEACALLDELGEQATVLAGGTDVLHKMKVGKLAPGHLVSLKNLDDLRTISHEPGRGIVMGALTSHN
AIYTSRLLQKRYLSLPMAAHTMASNQICNMGTVGGNIVNGVPSADLPPILIALNASIRLVSSKGERTMPLEDFFHGSAET
VIAPGELLADITIPDQPTTGSTYMKFGLRRSGALAVVGVAVSVTVKGDILEDVRIVLASAAPTVMRARKAEDRLRGKKIS
DELLAEAGEEAAAESRPRDSIRGSAEYRRNLVGVLTKRALRKAIDEGHS
>Mature_289_residues
MYMPDFEYHTPETLTEACALLDELGEQATVLAGGTDVLHKMKVGKLAPGHLVSLKNLDDLRTISHEPGRGIVMGALTSHN
AIYTSRLLQKRYLSLPMAAHTMASNQICNMGTVGGNIVNGVPSADLPPILIALNASIRLVSSKGERTMPLEDFFHGSAET
VIAPGELLADITIPDQPTTGSTYMKFGLRRSGALAVVGVAVSVTVKGDILEDVRIVLASAAPTVMRARKAEDRLRGKKIS
DELLAEAGEEAAAESRPRDSIRGSAEYRRNLVGVLTKRALRKAIDEGHS

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1319

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=282, Percent_Identity=25.886524822695, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1789231, Length=285, Percent_Identity=30.1754385964912, Blast_Score=132, Evalue=3e-32,
Organism=Drosophila melanogaster, GI17737937, Length=275, Percent_Identity=28.3636363636364, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005107
- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR002346 [H]

Pfam domain/function: PF03450 CO_deh_flav_C; PF00941 FAD_binding_5 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 30946; Mature: 30946

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYMPDFEYHTPETLTEACALLDELGEQATVLAGGTDVLHKMKVGKLAPGHLVSLKNLDDL
CCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCCCCEEEECCCHHH
RTISHEPGRGIVMGALTSHNAIYTSRLLQKRYLSLPMAAHTMASNQICNMGTVGGNIVNG
HHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCHHHCC
VPSADLPPILIALNASIRLVSSKGERTMPLEDFFHGSAETVIAPGELLADITIPDQPTTG
CCCCCCCEEEEEECCEEEEEECCCCCCCCHHHHHCCCCCEEEECHHHEEEEECCCCCCCC
STYMKFGLRRSGALAVVGVAVSVTVKGDILEDVRIVLASAAPTVMRARKAEDRLRGKKIS
CHHHHHCCCCCCCEEEEEEEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCH
DELLAEAGEEAAAESRPRDSIRGSAEYRRNLVGVLTKRALRKAIDEGHS
HHHHHHCCHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYMPDFEYHTPETLTEACALLDELGEQATVLAGGTDVLHKMKVGKLAPGHLVSLKNLDDL
CCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCCCCEEEECCCHHH
RTISHEPGRGIVMGALTSHNAIYTSRLLQKRYLSLPMAAHTMASNQICNMGTVGGNIVNG
HHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCHHHCC
VPSADLPPILIALNASIRLVSSKGERTMPLEDFFHGSAETVIAPGELLADITIPDQPTTG
CCCCCCCEEEEEECCEEEEEECCCCCCCCHHHHHCCCCCEEEECHHHEEEEECCCCCCCC
STYMKFGLRRSGALAVVGVAVSVTVKGDILEDVRIVLASAAPTVMRARKAEDRLRGKKIS
CHHHHHCCCCCCCEEEEEEEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCH
DELLAEAGEEAAAESRPRDSIRGSAEYRRNLVGVLTKRALRKAIDEGHS
HHHHHHCCHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]