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The map label for this gene is mshA [H]

Identifier: 78223208

GI number: 78223208

Start: 2239327

End: 2240469

Strand: Reverse

Name: mshA [H]

Synonym: Gmet_2001

Alternate gene names: 78223208

Gene position: 2240469-2239327 (Counterclockwise)

Preceding gene: 78223209

Following gene: 78223207

Centisome position: 56.05

GC content: 57.74

Gene sequence:

>1143_bases
TTGACAGTGGAGCCTCTCCATATACTACACCTCATAAGTACCTCCGGCCTTTTCGGCGCCGAGAGGGTGCTGCTCGAACT
GGCGTCACAATCCCGTTCCCTCGGCATGCATGTGACCGTGGCGGCTTTGAAGAACAGCCGAAATCCGAATACGGAATTGG
CAGAGGCTGCCCGCGGGGCGGGGCTGCCAACCTTGGTTGTCCCGTGCGGAGGGCGTTTCGACGCAGGAGTCGTCGGCATC
CTGACGGAGGAGATCCGGAAGAGCGGGACGCAGATCATCCATTCCCACAATTACAAGAGCAATTACTACGCTCGGCAGGC
CGCGGAGCTGTCAGGCGCCCGCTGGATCGTCACCAATCATGGGCGGAGGGCCGGTTTTAAACTGTTTCTCTATGCTCTTC
TCGATGCCATGCTGGTGAGGAAGGCTGATCGAGTGGTTGCCGTATCTCCGAAAATTGCCGATCGGCTTGCGGTATTGGGA
ATCGGTAGGGATGGGCTGTCGGTCATTGACAACGGGGTCGATTTCAGCCGTTTCGAAAGCCTGCCGACCAAGGCAGATGC
AGGAAATGTGCTGGGGGTAGCCGGTAGTTCCTATGTGATCGGTACAGTGGGGGCGCTCACGGAGGAAAAGGGGCACCGTC
ATTTGCTGCAGGCTGTCAAGAGCGTCCGCAAATCGATCCCGAATGTCGTCTGTGTTGTGGTGGGGGATGGTCCTGAGAGG
CGGCGCCTTGAGCAGTTGGCTCGGGAAGAGGGGATTGAACAAACTGCTATTTTTACGGGGAAGCGGGATGACGTTCCGTC
CATTTTGCCCCGCTTCGATCTCTTTGTTCTTCCGTCCCTCAGTGAAGGTCTTCCCATGGCCCTTCTGGAGGCTCAGGCGG
CAAAGGTTCCAGCCATAGCCACCAATGTGGGGGCGATTGCCACAGTAATTAATAATGGTGTCACCGGTGTTGTTGTCTCC
CCGGGTGATGTCCCGGCCCTTGCCGAAGCCATAATCCGCAGCCACGACGAGGCGGACAAGGCCCGCTGCATGGCCCTGAA
AGGATACGAACGCGTGAAAGTGCATTACTCTGCCGATACCATGGCGCAGCGCTATATCGAAATCTACCGGGGTATGATCG
GAGCAGGAGGAGCGATCGGATGA

Upstream 100 bases:

>100_bases
CGGTGCGGGGGAGTGTGGATGCAACGCGGGATGTGGCGACGCGCTACATGAATTCCCTGGCTCCGGCTCTCACCTCTTTT
TTCTGAACCGGCCCGAGCTG

Downstream 100 bases:

>100_bases
ACGTTTTGTTCCTCTCCACCAAGAGCCCCTATCCCCTCATCAACGGCCACAGTCTGCGCACCTATCACACGCTGCGGGAT
GCAGCGCGACGCCATGACGT

Product: glycosyl transferase, group 1

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase; GlcNAc-Ins-P N-acetylglucosaminyltransferase [H]

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MTVEPLHILHLISTSGLFGAERVLLELASQSRSLGMHVTVAALKNSRNPNTELAEAARGAGLPTLVVPCGGRFDAGVVGI
LTEEIRKSGTQIIHSHNYKSNYYARQAAELSGARWIVTNHGRRAGFKLFLYALLDAMLVRKADRVVAVSPKIADRLAVLG
IGRDGLSVIDNGVDFSRFESLPTKADAGNVLGVAGSSYVIGTVGALTEEKGHRHLLQAVKSVRKSIPNVVCVVVGDGPER
RRLEQLAREEGIEQTAIFTGKRDDVPSILPRFDLFVLPSLSEGLPMALLEAQAAKVPAIATNVGAIATVINNGVTGVVVS
PGDVPALAEAIIRSHDEADKARCMALKGYERVKVHYSADTMAQRYIEIYRGMIGAGGAIG

Sequences:

>Translated_380_residues
MTVEPLHILHLISTSGLFGAERVLLELASQSRSLGMHVTVAALKNSRNPNTELAEAARGAGLPTLVVPCGGRFDAGVVGI
LTEEIRKSGTQIIHSHNYKSNYYARQAAELSGARWIVTNHGRRAGFKLFLYALLDAMLVRKADRVVAVSPKIADRLAVLG
IGRDGLSVIDNGVDFSRFESLPTKADAGNVLGVAGSSYVIGTVGALTEEKGHRHLLQAVKSVRKSIPNVVCVVVGDGPER
RRLEQLAREEGIEQTAIFTGKRDDVPSILPRFDLFVLPSLSEGLPMALLEAQAAKVPAIATNVGAIATVINNGVTGVVVS
PGDVPALAEAIIRSHDEADKARCMALKGYERVKVHYSADTMAQRYIEIYRGMIGAGGAIG
>Mature_379_residues
TVEPLHILHLISTSGLFGAERVLLELASQSRSLGMHVTVAALKNSRNPNTELAEAARGAGLPTLVVPCGGRFDAGVVGIL
TEEIRKSGTQIIHSHNYKSNYYARQAAELSGARWIVTNHGRRAGFKLFLYALLDAMLVRKADRVVAVSPKIADRLAVLGI
GRDGLSVIDNGVDFSRFESLPTKADAGNVLGVAGSSYVIGTVGALTEEKGHRHLLQAVKSVRKSIPNVVCVVVGDGPERR
RLEQLAREEGIEQTAIFTGKRDDVPSILPRFDLFVLPSLSEGLPMALLEAQAAKVPAIATNVGAIATVINNGVTGVVVSP
GDVPALAEAIIRSHDEADKARCMALKGYERVKVHYSADTMAQRYIEIYRGMIGAGGAIG

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway [H]

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788357, Length=194, Percent_Identity=29.3814432989691, Blast_Score=79, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI9755344, Length=300, Percent_Identity=26, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR017814 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.250 [H]

Molecular weight: Translated: 40483; Mature: 40352

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVEPLHILHLISTSGLFGAERVLLELASQSRSLGMHVTVAALKNSRNPNTELAEAARGA
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEEHHCCCCCCHHHHHHHHCC
GLPTLVVPCGGRFDAGVVGILTEEIRKSGTQIIHSHNYKSNYYARQAAELSGARWIVTNH
CCCEEEEECCCCCCCCHHHHHHHHHHHCCHHEEECCCCCCCHHHHHHHHCCCCEEEEECC
GRRAGFKLFLYALLDAMLVRKADRVVAVSPKIADRLAVLGIGRDGLSVIDNGVDFSRFES
CCHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHCEEEEEECCCCHHHHCCCCCHHHHHC
LPTKADAGNVLGVAGSSYVIGTVGALTEEKGHRHLLQAVKSVRKSIPNVVCVVVGDGPER
CCCCCCCCCEEEECCCCEEEEEHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHH
RRLEQLAREEGIEQTAIFTGKRDDVPSILPRFDLFVLPSLSEGLPMALLEAQAAKVPAIA
HHHHHHHHHCCCCEEEEECCCCCCCHHHHCCCCEEECCCCCCCCCHHHHHHHHHCCCHHH
TNVGAIATVINNGVTGVVVSPGDVPALAEAIIRSHDEADKARCMALKGYERVKVHYSADT
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCHHHHHHHHEECCCEEEEEEECHHH
MAQRYIEIYRGMIGAGGAIG
HHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TVEPLHILHLISTSGLFGAERVLLELASQSRSLGMHVTVAALKNSRNPNTELAEAARGA
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEEHHCCCCCCHHHHHHHHCC
GLPTLVVPCGGRFDAGVVGILTEEIRKSGTQIIHSHNYKSNYYARQAAELSGARWIVTNH
CCCEEEEECCCCCCCCHHHHHHHHHHHCCHHEEECCCCCCCHHHHHHHHCCCCEEEEECC
GRRAGFKLFLYALLDAMLVRKADRVVAVSPKIADRLAVLGIGRDGLSVIDNGVDFSRFES
CCHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHCEEEEEECCCCHHHHCCCCCHHHHHC
LPTKADAGNVLGVAGSSYVIGTVGALTEEKGHRHLLQAVKSVRKSIPNVVCVVVGDGPER
CCCCCCCCCEEEECCCCEEEEEHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHH
RRLEQLAREEGIEQTAIFTGKRDDVPSILPRFDLFVLPSLSEGLPMALLEAQAAKVPAIA
HHHHHHHHHCCCCEEEEECCCCCCCHHHHCCCCEEECCCCCCCCCHHHHHHHHHCCCHHH
TNVGAIATVINNGVTGVVVSPGDVPALAEAIIRSHDEADKARCMALKGYERVKVHYSADT
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCHHHHHHHHEECCCEEEEEEECHHH
MAQRYIEIYRGMIGAGGAIG
HHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA