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The map label for this gene is dspA [H]

Identifier: 78223152

GI number: 78223152

Start: 2171991

End: 2174063

Strand: Reverse

Name: dspA [H]

Synonym: Gmet_1945

Alternate gene names: 78223152

Gene position: 2174063-2171991 (Counterclockwise)

Preceding gene: 78223157

Following gene: 78223151

Centisome position: 54.39

GC content: 49.59

Gene sequence:

>2073_bases
ATGAAAAAAACTCTAGAAAAAAGAATAATCATCTTCGCCTTCATTATTCTTTTTCTCACGATTGCCGCAAATTCAGGTAT
GGATATCGTGGGGTTCAGAAGAGACTACATTCAGGCCCTTATCATGAGGTCTCAAAGCCTCGGTTCATCTCTGCGGGCGA
ATTTGGAAAAGGTGGTGGGGCTCGGTATCGATGTCAAAGACATCGAGGGATTGAATGATAAATGTCGCGAAGTTGTCGCA
TCGAGCCCTGAAGTTGCCTACTGTATTATTACTGACAGTGAGGGGAATATCCTTCACCTGAACGATCCTGTCTACCGGAA
CATCCGTTTCGATATTATTCGAAGGGCATTTACAACCCGCCTCGATCAGAACATCCACCTCATCGGTGACGACGGTTCCT
ACTACGATACCGTTACGCCGGTTCGCTCCCCTGACGGAAAGCAAGTCGCCCTCATACACATTGGTTTTTCGGTACATGTC
GTGTCCGCGAAGGTGCAGGTGATAATCATTCGTTCGCTACTCCTTCTTGCGGTTGTCTTCCTGGTCTCATTTTCGTTGGT
GGTGATTTTTGTCAAGCGAAACATCGGCCAGCCCATTGCTGCTCTTCTGGCTGGTGTCAGGAAGGTATCGGAAGGAGAGT
TCAATCACCGGATTAATCAATTGCCTGTTTATGAATTCAATGAATTGGCCAGCAGCGTGAATCTCATGTCTGATACCCTC
AAGAATCGCGAAGAGGAGATACGGAGCAATTATCAGGAACTGGAAAATATCCACAACGACCTTCATTCCTCGTATCTCAA
GCTGGAGAGCCTGAGCCTCGACCTGGAAAAATCGGAGGAACTCTACAAATCGCTTCTCGAAGATGCAAGTGATGCCATTG
TCGTCACTGACGAAAACGACATGGTCAAGATGGTCAACAAAATGGCTGAAGACTTCTTTGGCCATGATGCGGCCGAACTT
GTCGGATTATCCCTTAGTCGTATGCTCACGCTGGTGGGAACCCAGAATTCCTCGATTGTCTACAATTTTTTTCAGGTGGC
GGGGACTGGTAAGCATGTGGCGGAAGAAATTAAGTTCCTCAGGAAGGACAAAGAATTAGTGGTTGGTCTCATTCACGCCA
ACATCGTCACCATTGGTGCAGAACGGCTGATTCAGGCCATCATCCGTGACGTCACCCGTGAGCGAGAAATTCTGCTGAAC
CTTGAGAAGAGTGCAGCCGACTTGGCACGCCTTAATAAGATGAAGGATTCGTTCCTCGGCATAGCATCCCACGAACTCAA
GACTCCCCTCACGGTTATCATGGGGTATGCGGAGCTTATCCTGACGGACCCGCCTTGCCAGGTCGATCCCAATATCATCG
ACATGGTGAACAACATTGCCGGTGCCGCTAACCGACTCGACAACATCGTCAAGGACATGGTCGACGTCTCGATGATCGAC
GAGAAACGGTTGCAGTTGAAACTCAGCGAGGTTGATGTGAACCGGTTGGTGGAGGATTCCCTGAATGAACTCCGCTTTTT
TGTGTCCATGCGCAAGCAACAATTGGTTTTTGAGCTTGATGATGCTATTCCGGCCATCAAGGGGGACACGGTTCGACTCA
TGCAACTCCTTTCGAATGTGATCGGCAATGCCATCAAGTTCACTCCCGATGGAGGACGGATTATGGTTTCCACGCGAGCC
AAGTATATTTTGCGCTCCAAGCAGATTCCAACGGTGGATCCGGTCCAGTCGCTGGTCAATATCGGCAAGGACCAGCATCT
CTATGTGGAGATAACCGTGGCCGACACGGGGATTGGTATCGACATCGACGACCAGCTCAGAATATTTGACAAGTTCTATG
AAGCGGGAAATATCGAGGAACACTCCTCGGGAAAAGTTGCCTTCAAGTCGCGTGGGGCCGGCCTCGGTCTTTCGATCTCC
AAGGGAATAGTAGAAATGCATGGCGGTGAAATCTGGGTCGAATCGCCCGGCTACAACCCCGACCAATTTCCCGGCTCCAC
CTTTCACATCGTACTCCCCCTCAACCCCATAACCGGTGACGGGACCATCGATTATCTCAACCTTCTCAAGTAG

Upstream 100 bases:

>100_bases
GGAGATGCATTGGTTGAATTTTAAAGGTTATTGCTTTGAGGAAATGTGGTAGTATGAATTCGCTTGATAAGCCTAACTAG
CCGAATAATCAAATTAATTT

Downstream 100 bases:

>100_bases
TTTCCTTGTTGACTCATTAGAAAAATCTTCCGTGTTTAGCCTTGAATATACGCATCCTTTCCGGTATAAAATTTGAGTTT
ATTGAGCGATGGGGGATGGT

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 690; Mature: 690

Protein sequence:

>690_residues
MKKTLEKRIIIFAFIILFLTIAANSGMDIVGFRRDYIQALIMRSQSLGSSLRANLEKVVGLGIDVKDIEGLNDKCREVVA
SSPEVAYCIITDSEGNILHLNDPVYRNIRFDIIRRAFTTRLDQNIHLIGDDGSYYDTVTPVRSPDGKQVALIHIGFSVHV
VSAKVQVIIIRSLLLLAVVFLVSFSLVVIFVKRNIGQPIAALLAGVRKVSEGEFNHRINQLPVYEFNELASSVNLMSDTL
KNREEEIRSNYQELENIHNDLHSSYLKLESLSLDLEKSEELYKSLLEDASDAIVVTDENDMVKMVNKMAEDFFGHDAAEL
VGLSLSRMLTLVGTQNSSIVYNFFQVAGTGKHVAEEIKFLRKDKELVVGLIHANIVTIGAERLIQAIIRDVTREREILLN
LEKSAADLARLNKMKDSFLGIASHELKTPLTVIMGYAELILTDPPCQVDPNIIDMVNNIAGAANRLDNIVKDMVDVSMID
EKRLQLKLSEVDVNRLVEDSLNELRFFVSMRKQQLVFELDDAIPAIKGDTVRLMQLLSNVIGNAIKFTPDGGRIMVSTRA
KYILRSKQIPTVDPVQSLVNIGKDQHLYVEITVADTGIGIDIDDQLRIFDKFYEAGNIEEHSSGKVAFKSRGAGLGLSIS
KGIVEMHGGEIWVESPGYNPDQFPGSTFHIVLPLNPITGDGTIDYLNLLK

Sequences:

>Translated_690_residues
MKKTLEKRIIIFAFIILFLTIAANSGMDIVGFRRDYIQALIMRSQSLGSSLRANLEKVVGLGIDVKDIEGLNDKCREVVA
SSPEVAYCIITDSEGNILHLNDPVYRNIRFDIIRRAFTTRLDQNIHLIGDDGSYYDTVTPVRSPDGKQVALIHIGFSVHV
VSAKVQVIIIRSLLLLAVVFLVSFSLVVIFVKRNIGQPIAALLAGVRKVSEGEFNHRINQLPVYEFNELASSVNLMSDTL
KNREEEIRSNYQELENIHNDLHSSYLKLESLSLDLEKSEELYKSLLEDASDAIVVTDENDMVKMVNKMAEDFFGHDAAEL
VGLSLSRMLTLVGTQNSSIVYNFFQVAGTGKHVAEEIKFLRKDKELVVGLIHANIVTIGAERLIQAIIRDVTREREILLN
LEKSAADLARLNKMKDSFLGIASHELKTPLTVIMGYAELILTDPPCQVDPNIIDMVNNIAGAANRLDNIVKDMVDVSMID
EKRLQLKLSEVDVNRLVEDSLNELRFFVSMRKQQLVFELDDAIPAIKGDTVRLMQLLSNVIGNAIKFTPDGGRIMVSTRA
KYILRSKQIPTVDPVQSLVNIGKDQHLYVEITVADTGIGIDIDDQLRIFDKFYEAGNIEEHSSGKVAFKSRGAGLGLSIS
KGIVEMHGGEIWVESPGYNPDQFPGSTFHIVLPLNPITGDGTIDYLNLLK
>Mature_690_residues
MKKTLEKRIIIFAFIILFLTIAANSGMDIVGFRRDYIQALIMRSQSLGSSLRANLEKVVGLGIDVKDIEGLNDKCREVVA
SSPEVAYCIITDSEGNILHLNDPVYRNIRFDIIRRAFTTRLDQNIHLIGDDGSYYDTVTPVRSPDGKQVALIHIGFSVHV
VSAKVQVIIIRSLLLLAVVFLVSFSLVVIFVKRNIGQPIAALLAGVRKVSEGEFNHRINQLPVYEFNELASSVNLMSDTL
KNREEEIRSNYQELENIHNDLHSSYLKLESLSLDLEKSEELYKSLLEDASDAIVVTDENDMVKMVNKMAEDFFGHDAAEL
VGLSLSRMLTLVGTQNSSIVYNFFQVAGTGKHVAEEIKFLRKDKELVVGLIHANIVTIGAERLIQAIIRDVTREREILLN
LEKSAADLARLNKMKDSFLGIASHELKTPLTVIMGYAELILTDPPCQVDPNIIDMVNNIAGAANRLDNIVKDMVDVSMID
EKRLQLKLSEVDVNRLVEDSLNELRFFVSMRKQQLVFELDDAIPAIKGDTVRLMQLLSNVIGNAIKFTPDGGRIMVSTRA
KYILRSKQIPTVDPVQSLVNIGKDQHLYVEITVADTGIGIDIDDQLRIFDKFYEAGNIEEHSSGKVAFKSRGAGLGLSIS
KGIVEMHGGEIWVESPGYNPDQFPGSTFHIVLPLNPITGDGTIDYLNLLK

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc; May Activate Atoc By Phosphorylation. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=458, Percent_Identity=25.9825327510917, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1789149, Length=277, Percent_Identity=29.9638989169675, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI145693157, Length=414, Percent_Identity=26.3285024154589, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI48994928, Length=450, Percent_Identity=24.6666666666667, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1788393, Length=271, Percent_Identity=30.9963099630996, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1786600, Length=423, Percent_Identity=24.5862884160757, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1788713, Length=290, Percent_Identity=24.4827586206897, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87081816, Length=288, Percent_Identity=28.4722222222222, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788279, Length=246, Percent_Identity=26.4227642276423, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1790300, Length=390, Percent_Identity=24.1025641025641, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1790861, Length=229, Percent_Identity=27.0742358078603, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786783, Length=262, Percent_Identity=26.3358778625954, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786912, Length=283, Percent_Identity=24.7349823321555, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 76889; Mature: 76889

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTLEKRIIIFAFIILFLTIAANSGMDIVGFRRDYIQALIMRSQSLGSSLRANLEKVVG
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGIDVKDIEGLNDKCREVVASSPEVAYCIITDSEGNILHLNDPVYRNIRFDIIRRAFTTR
CCCCHHHHCCCCHHHHHHHHCCCCEEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHH
LDQNIHLIGDDGSYYDTVTPVRSPDGKQVALIHIGFSVHVVSAKVQVIIIRSLLLLAVVF
CCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEECEEEEEEHHHHHHHHHHHHHHHHHHH
LVSFSLVVIFVKRNIGQPIAALLAGVRKVSEGEFNHRINQLPVYEFNELASSVNLMSDTL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHH
KNREEEIRSNYQELENIHNDLHSSYLKLESLSLDLEKSEELYKSLLEDASDAIVVTDEND
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCH
MVKMVNKMAEDFFGHDAAELVGLSLSRMLTLVGTQNSSIVYNFFQVAGTGKHVAEEIKFL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHCCCCHHHHHHHHHH
RKDKELVVGLIHANIVTIGAERLIQAIIRDVTREREILLNLEKSAADLARLNKMKDSFLG
HCCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHH
IASHELKTPLTVIMGYAELILTDPPCQVDPNIIDMVNNIAGAANRLDNIVKDMVDVSMID
HHHHHHCCHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EKRLQLKLSEVDVNRLVEDSLNELRFFVSMRKQQLVFELDDAIPAIKGDTVRLMQLLSNV
CHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
IGNAIKFTPDGGRIMVSTRAKYILRSKQIPTVDPVQSLVNIGKDQHLYVEITVADTGIGI
HCCCEEECCCCCEEEEECHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEEEECCCCCC
DIDDQLRIFDKFYEAGNIEEHSSGKVAFKSRGAGLGLSISKGIVEMHGGEIWVESPGYNP
CCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCHHCCHHEECCCEEEEECCCCCC
DQFPGSTFHIVLPLNPITGDGTIDYLNLLK
CCCCCCEEEEEEECCCCCCCCCCHHHHHCC
>Mature Secondary Structure
MKKTLEKRIIIFAFIILFLTIAANSGMDIVGFRRDYIQALIMRSQSLGSSLRANLEKVVG
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGIDVKDIEGLNDKCREVVASSPEVAYCIITDSEGNILHLNDPVYRNIRFDIIRRAFTTR
CCCCHHHHCCCCHHHHHHHHCCCCEEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHH
LDQNIHLIGDDGSYYDTVTPVRSPDGKQVALIHIGFSVHVVSAKVQVIIIRSLLLLAVVF
CCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEECEEEEEEHHHHHHHHHHHHHHHHHHH
LVSFSLVVIFVKRNIGQPIAALLAGVRKVSEGEFNHRINQLPVYEFNELASSVNLMSDTL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHH
KNREEEIRSNYQELENIHNDLHSSYLKLESLSLDLEKSEELYKSLLEDASDAIVVTDEND
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCH
MVKMVNKMAEDFFGHDAAELVGLSLSRMLTLVGTQNSSIVYNFFQVAGTGKHVAEEIKFL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHCCCCHHHHHHHHHH
RKDKELVVGLIHANIVTIGAERLIQAIIRDVTREREILLNLEKSAADLARLNKMKDSFLG
HCCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHH
IASHELKTPLTVIMGYAELILTDPPCQVDPNIIDMVNNIAGAANRLDNIVKDMVDVSMID
HHHHHHCCHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EKRLQLKLSEVDVNRLVEDSLNELRFFVSMRKQQLVFELDDAIPAIKGDTVRLMQLLSNV
CHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
IGNAIKFTPDGGRIMVSTRAKYILRSKQIPTVDPVQSLVNIGKDQHLYVEITVADTGIGI
HCCCEEECCCCCEEEEECHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEEEECCCCCC
DIDDQLRIFDKFYEAGNIEEHSSGKVAFKSRGAGLGLSISKGIVEMHGGEIWVESPGYNP
CCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCHHCCHHEECCCEEEEECCCCCC
DQFPGSTFHIVLPLNPITGDGTIDYLNLLK
CCCCCCEEEEEEECCCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8535519; 8905231; 3141423 [H]