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The map label for this gene is acpS

Identifier: 78223091

GI number: 78223091

Start: 2099487

End: 2099867

Strand: Reverse

Name: acpS

Synonym: Gmet_1884

Alternate gene names: 78223091

Gene position: 2099867-2099487 (Counterclockwise)

Preceding gene: 78223092

Following gene: 78223090

Centisome position: 52.53

GC content: 54.86

Gene sequence:

>381_bases
GTGATTTTCGGCACCGGCATTGATATCGTCGACATAACCCGCTTCGAGCGTTTTCTGGAAGAGAGGAATACGCGTCTGTT
CGAGCGCCTGTTCACCATTCATGAGCAAGAATACTGTGCGGGAAAGGCCCACAGTGCCCAGCACTATGCCCTTCGTTTCG
CAGCCAAGGAGGCCTTTCTCAAGGCGTGCGGCCTCGGGCTTCGCGAAGGATTGACCTGGCATGACGTGGAGGTTGTCAAC
GACTCCCTCGGCAAGCCGGACCTGCGACTTTACGGCAAGGCACAACAGCTATTCGCTGATATGAATCTCTCGAAGACATT
TGTATCCCTTTCCCATGACGGGAATTTTGCCGTCGCCATGGTGGTTCTGGAGCGGGTATGA

Upstream 100 bases:

>100_bases
TATAACATCGGCCATTCCATCATCTCCCGGGCGGTCCTTGTGGGACTCGACCGGGCAGTGCGCGACATGGTGGATCTCAT
CAAGTACGCCTGAGGTATCC

Downstream 100 bases:

>100_bases
AGGTTGTTACCGGCGAAACCATGCAGCGGATGGACCGTCGCTCCATCGAGGAATTCGGCATACCGGGCATTGACCTCATG
GAAAATGCCGGCCAGGGGTG

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MIFGTGIDIVDITRFERFLEERNTRLFERLFTIHEQEYCAGKAHSAQHYALRFAAKEAFLKACGLGLREGLTWHDVEVVN
DSLGKPDLRLYGKAQQLFADMNLSKTFVSLSHDGNFAVAMVVLERV

Sequences:

>Translated_126_residues
MIFGTGIDIVDITRFERFLEERNTRLFERLFTIHEQEYCAGKAHSAQHYALRFAAKEAFLKACGLGLREGLTWHDVEVVN
DSLGKPDLRLYGKAQQLFADMNLSKTFVSLSHDGNFAVAMVVLERV
>Mature_126_residues
MIFGTGIDIVDITRFERFLEERNTRLFERLFTIHEQEYCAGKAHSAQHYALRFAAKEAFLKACGLGLREGLTWHDVEVVN
DSLGKPDLRLYGKAQQLFADMNLSKTFVSLSHDGNFAVAMVVLERV

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=125, Percent_Identity=39.2, Blast_Score=87, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6325025, Length=120, Percent_Identity=32.5, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_GEOMG (Q39UG1)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_384838.1
- ProteinModelPortal:   Q39UG1
- SMR:   Q39UG1
- STRING:   Q39UG1
- GeneID:   3739160
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_1884
- NMPDR:   fig|269799.3.peg.2147
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- PhylomeDB:   Q39UG1
- ProtClustDB:   PRK14656
- BioCyc:   GMET269799:GMET_1884-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14353; Mature: 14353

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFGTGIDIVDITRFERFLEERNTRLFERLFTIHEQEYCAGKAHSAQHYALRFAAKEAFL
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
KACGLGLREGLTWHDVEVVNDSLGKPDLRLYGKAQQLFADMNLSKTFVSLSHDGNFAVAM
HHHCCHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHEEEECCCCCCHHHH
VVLERV
HHHHCC
>Mature Secondary Structure
MIFGTGIDIVDITRFERFLEERNTRLFERLFTIHEQEYCAGKAHSAQHYALRFAAKEAFL
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
KACGLGLREGLTWHDVEVVNDSLGKPDLRLYGKAQQLFADMNLSKTFVSLSHDGNFAVAM
HHHCCHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHEEEECCCCCCHHHH
VVLERV
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA