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The map label for this gene is cat1 [H]

Identifier: 78222939

GI number: 78222939

Start: 1946499

End: 1948061

Strand: Reverse

Name: cat1 [H]

Synonym: Gmet_1730

Alternate gene names: 78222939

Gene position: 1948061-1946499 (Counterclockwise)

Preceding gene: 78222941

Following gene: 78222938

Centisome position: 48.73

GC content: 60.97

Gene sequence:

>1563_bases
ATGTCTGAATTGCTCAACAGGATAAGAAGAAAGAGTCTGCACGACAGAATCAGGAAGGTCGAAGAGGTCATTCCCCTGTT
CAAGCACGGGATGAATCTCGGCTGGTCAGGCTTCACCCCTGCCGGCTACCCGAAAGCAATACCCATCGCCCTTGCGGATT
ACGTGGAGAAGAACCAGCTCCAGGGGAAGATGAGATTCAACCTCTTCATCGGCGCCTCCGTCGGCGTCGAGACCGAAGAC
CGCTGGGCATCCCTTGACATGATCGACCGCCGCTGGCCCTACCAGACCGGCAAAAACATCCAGGCCGGCATCAACGAAGG
GCGCATCCGCATGGGGGACAAGCACCTCTCCATGTTCGCCCAAGACTTGGGCTACGGCTTCTACACCAAGGACAATGGCG
GCCGTCTCGACATCGGCATCATCGAATGTTCCGCCATCACCGAGGACGGCGGCCTCGTCCTGACCGCCTCCTGCGGCGCC
GTGCCGGAGATCGTGCAGATTGCCGACCGGCTCATTATCGAGATCAACACCGCCATCCCGAACTACGAAGGGCTCCACGA
CATCATCGACCCGGTCAATCCCCCCAACCGCCTCCCCTACCTCCTCAGCCGGGTTGACGACCGTGCCGGCTCGCCCTATG
TCCGGATCGACACCGACAAAATCGTCGCCATCGTCGAATCGCAGCACCCCGACAACGGTCGTGCCTTCAGCGAGCAAGAC
GACACCTCCGCGGCCATCGCCAACAACATCCTCGACTTCTTCCAGTTCGAGGTAAAGGAAGGCCGCCTGCCGAAGAACCT
CCTGCCGCTCCAGTCTGGCGTGGGTTCCATCGCCAACGCCGTCATCGGTGGCTTGGCCAAGGGACCGTTCTCGGGTCTCA
AGGTCTGGACCGAAGTGCTGCAGGACACCATGCTCGACCTCTTCGATTCGGGGAAACTGGATTTTGCCTCCACGGTCTCC
CTCTCCTTCTCGGTCGATGGCTTTAAGCGCTTCTACGGCAACTGGGAGAAGTACAGCAACAAGGTGATCATGCGTCCCCT
CTCCGTCGCCAACCACCCCGAGCCGATCCGGCGCCTGGGTTGCATCGCCATGAACACCCCCGTGGAATTCGACATCTACG
CCCACGCCAACTCCACCCTCGTGGGGGGAACCCGGATGATTAACGGCATCGGCGGCTCCGGCGACTTCCTGCGCAACGCC
TATCTCTCCATCATGCACACGCCGTCGGCCCGCCCCAGCAAGACCGACCCGACCGGCATCACCTGCGTGGTGCCGCACGT
GCCGCACGTTGACCACACCGAGCACGACCTCGACGTGCTAGTCACGGAGCAGGGGCTTGCCGACCTGAGGGGACTCGATC
CGAAAAGCCGCGCCAAGCTCATCATCGACAAGTGCGCCCACCCGGACTACAAGCCGCTGCTCCGTGAGTACCTCGAAATC
GCGACGAAAGAGTGTTTGGCCCGCAAAGCCGGCCACGAACCGCAACTCCTTGACCGGGTCTTCAAGATGCAGGTGAACCT
GGCCAAGAACGGCACCATGAAGATCGCAAACTGGGATATCTGA

Upstream 100 bases:

>100_bases
CGTTTGATACGAAACCATTCAATTGTCGATTTCAGGGCCGGCACAGCACTCACACTGATACGCCAGGCACCAATATCCAG
GAGAAGGAGGATGTAAGTAG

Downstream 100 bases:

>100_bases
ACCTGTATCGGCCCACAGGGATGCCGAAACGGAAAGGGAGGCAACGACATGCGTGATTCCGACCAACTGCCGAGGTATTA
CCTCGGAACGGCGCTGCAGG

Product: Acetyl-CoA hydrolase/transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 519

Protein sequence:

>520_residues
MSELLNRIRRKSLHDRIRKVEEVIPLFKHGMNLGWSGFTPAGYPKAIPIALADYVEKNQLQGKMRFNLFIGASVGVETED
RWASLDMIDRRWPYQTGKNIQAGINEGRIRMGDKHLSMFAQDLGYGFYTKDNGGRLDIGIIECSAITEDGGLVLTASCGA
VPEIVQIADRLIIEINTAIPNYEGLHDIIDPVNPPNRLPYLLSRVDDRAGSPYVRIDTDKIVAIVESQHPDNGRAFSEQD
DTSAAIANNILDFFQFEVKEGRLPKNLLPLQSGVGSIANAVIGGLAKGPFSGLKVWTEVLQDTMLDLFDSGKLDFASTVS
LSFSVDGFKRFYGNWEKYSNKVIMRPLSVANHPEPIRRLGCIAMNTPVEFDIYAHANSTLVGGTRMINGIGGSGDFLRNA
YLSIMHTPSARPSKTDPTGITCVVPHVPHVDHTEHDLDVLVTEQGLADLRGLDPKSRAKLIIDKCAHPDYKPLLREYLEI
ATKECLARKAGHEPQLLDRVFKMQVNLAKNGTMKIANWDI

Sequences:

>Translated_520_residues
MSELLNRIRRKSLHDRIRKVEEVIPLFKHGMNLGWSGFTPAGYPKAIPIALADYVEKNQLQGKMRFNLFIGASVGVETED
RWASLDMIDRRWPYQTGKNIQAGINEGRIRMGDKHLSMFAQDLGYGFYTKDNGGRLDIGIIECSAITEDGGLVLTASCGA
VPEIVQIADRLIIEINTAIPNYEGLHDIIDPVNPPNRLPYLLSRVDDRAGSPYVRIDTDKIVAIVESQHPDNGRAFSEQD
DTSAAIANNILDFFQFEVKEGRLPKNLLPLQSGVGSIANAVIGGLAKGPFSGLKVWTEVLQDTMLDLFDSGKLDFASTVS
LSFSVDGFKRFYGNWEKYSNKVIMRPLSVANHPEPIRRLGCIAMNTPVEFDIYAHANSTLVGGTRMINGIGGSGDFLRNA
YLSIMHTPSARPSKTDPTGITCVVPHVPHVDHTEHDLDVLVTEQGLADLRGLDPKSRAKLIIDKCAHPDYKPLLREYLEI
ATKECLARKAGHEPQLLDRVFKMQVNLAKNGTMKIANWDI
>Mature_519_residues
SELLNRIRRKSLHDRIRKVEEVIPLFKHGMNLGWSGFTPAGYPKAIPIALADYVEKNQLQGKMRFNLFIGASVGVETEDR
WASLDMIDRRWPYQTGKNIQAGINEGRIRMGDKHLSMFAQDLGYGFYTKDNGGRLDIGIIECSAITEDGGLVLTASCGAV
PEIVQIADRLIIEINTAIPNYEGLHDIIDPVNPPNRLPYLLSRVDDRAGSPYVRIDTDKIVAIVESQHPDNGRAFSEQDD
TSAAIANNILDFFQFEVKEGRLPKNLLPLQSGVGSIANAVIGGLAKGPFSGLKVWTEVLQDTMLDLFDSGKLDFASTVSL
SFSVDGFKRFYGNWEKYSNKVIMRPLSVANHPEPIRRLGCIAMNTPVEFDIYAHANSTLVGGTRMINGIGGSGDFLRNAY
LSIMHTPSARPSKTDPTGITCVVPHVPHVDHTEHDLDVLVTEQGLADLRGLDPKSRAKLIIDKCAHPDYKPLLREYLEIA
TKECLARKAGHEPQLLDRVFKMQVNLAKNGTMKIANWDI

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=496, Percent_Identity=42.1370967741936, Blast_Score=383, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6319456, Length=518, Percent_Identity=57.1428571428571, Blast_Score=606, Evalue=1e-174,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 57660; Mature: 57529

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELLNRIRRKSLHDRIRKVEEVIPLFKHGMNLGWSGFTPAGYPKAIPIALADYVEKNQL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
QGKMRFNLFIGASVGVETEDRWASLDMIDRRWPYQTGKNIQAGINEGRIRMGDKHLSMFA
CCEEEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECHHHHHHHH
QDLGYGFYTKDNGGRLDIGIIECSAITEDGGLVLTASCGAVPEIVQIADRLIIEINTAIP
HHHCCCEEECCCCCEEEEEEEEEEEEECCCCEEEEECCCCCHHHHHHHHHEEEEEECCCC
NYEGLHDIIDPVNPPNRLPYLLSRVDDRAGSPYVRIDTDKIVAIVESQHPDNGRAFSEQD
CCCCHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEECCEEEEEEECCCCCCCCCCCCCC
DTSAAIANNILDFFQFEVKEGRLPKNLLPLQSGVGSIANAVIGGLAKGPFSGLKVWTEVL
CHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
QDTMLDLFDSGKLDFASTVSLSFSVDGFKRFYGNWEKYSNKVIMRPLSVANHPEPIRRLG
HHHHHHHHCCCCCCEEEEEEEEEEHHHHHHHCCCHHHHCCEEEEECHHHCCCCHHHHHHC
CIAMNTPVEFDIYAHANSTLVGGTRMINGIGGSGDFLRNAYLSIMHTPSARPSKTDPTGI
CEEECCCEEEEEEECCCCEEECCHHEEECCCCCHHHHHHHHHHEEECCCCCCCCCCCCCE
TCVVPHVPHVDHTEHDLDVLVTEQGLADLRGLDPKSRAKLIIDKCAHPDYKPLLREYLEI
EEEECCCCCCCCCCCCCEEEEECCCHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHH
ATKECLARKAGHEPQLLDRVFKMQVNLAKNGTMKIANWDI
HHHHHHHHHCCCCHHHHHHHHHHHHEECCCCEEEEECCCC
>Mature Secondary Structure 
SELLNRIRRKSLHDRIRKVEEVIPLFKHGMNLGWSGFTPAGYPKAIPIALADYVEKNQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
QGKMRFNLFIGASVGVETEDRWASLDMIDRRWPYQTGKNIQAGINEGRIRMGDKHLSMFA
CCEEEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECHHHHHHHH
QDLGYGFYTKDNGGRLDIGIIECSAITEDGGLVLTASCGAVPEIVQIADRLIIEINTAIP
HHHCCCEEECCCCCEEEEEEEEEEEEECCCCEEEEECCCCCHHHHHHHHHEEEEEECCCC
NYEGLHDIIDPVNPPNRLPYLLSRVDDRAGSPYVRIDTDKIVAIVESQHPDNGRAFSEQD
CCCCHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEECCEEEEEEECCCCCCCCCCCCCC
DTSAAIANNILDFFQFEVKEGRLPKNLLPLQSGVGSIANAVIGGLAKGPFSGLKVWTEVL
CHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
QDTMLDLFDSGKLDFASTVSLSFSVDGFKRFYGNWEKYSNKVIMRPLSVANHPEPIRRLG
HHHHHHHHCCCCCCEEEEEEEEEEHHHHHHHCCCHHHHCCEEEEECHHHCCCCHHHHHHC
CIAMNTPVEFDIYAHANSTLVGGTRMINGIGGSGDFLRNAYLSIMHTPSARPSKTDPTGI
CEEECCCEEEEEEECCCCEEECCHHEEECCCCCHHHHHHHHHHEEECCCCCCCCCCCCCE
TCVVPHVPHVDHTEHDLDVLVTEQGLADLRGLDPKSRAKLIIDKCAHPDYKPLLREYLEI
EEEECCCCCCCCCCCCCEEEEECCCHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHH
ATKECLARKAGHEPQLLDRVFKMQVNLAKNGTMKIANWDI
HHHHHHHHHCCCCHHHHHHHHHHHHEECCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]