Click here to switch to the map view.

The map label for this gene is gctA [H]

Identifier: 78222918

GI number: 78222918

Start: 1921138

End: 1922103

Strand: Reverse

Name: gctA [H]

Synonym: Gmet_1709

Alternate gene names: 78222918

Gene position: 1922103-1921138 (Counterclockwise)

Preceding gene: 78222919

Following gene: 78222917

Centisome position: 48.08

GC content: 63.04

Gene sequence:

>966_bases
ATGGGGACAGGTAAACGCATTACCTTGCAGCAGGCCGCCGAGATCATCAAGGACGGCTCCAGCCTCACCTTCTCCGGGTT
CACCATCTGGCGGCGCCCCATGGCCATCGTTTTCGAGCTGATCCGCCAGCAGAGACGGGGACTCCACCTCATCGAAGTGA
ATGGCGGCCCACACACCGAATTCCTCGTGGGAGCCGGGTGCGTCGACATCTGGGAGTCGTGCTGGGTGGGGCATGAACTC
TACGGCAAGTACGGCGCCAACCTCTCCCGCAAGGTGGGGAATAAGGAGATCATCGTTGAGGATTACAGCCATGCGGAGAT
GATGTTCCGCTTCGCTGCCGGTGCCGCCGGCGCTCCTTACGCCGTCACTCAGACATCCCTCGGCACGGACATCCACAACC
CTGAGTACGACATGCTCGGCCGGGCCGGCAAACGTGACGGGAAGCGGATCCCCAAGCACAAGTACCTCTTCACCGACGAC
CCCTTCTACGGCGCGGGCCCCCAGGTGCTGGTACCGGCGGCAAAGGCGGACATCGCCATCATGTGCGTCCAGCAGGTGGG
TGAGGAAGGGACGGTGCGGGTCAACGGCCAGTACTACTCCGACCCCGAGGCGGCCCGCACCGCGGACATCACCATCGTTA
TGGCCGAAGAGATCGTCCCCGAGGAGTACCTGCGCCGGGAGGCCGACCGCAACACCATCACCAGCTTCGAGGTGGACTAC
ATCGTGGAGTGTCCCTATGGCGCCCACCCCACAGGCATGTTCGGCCGCTACGACGTGGACGGTGCTTTCCTCAAGGACTT
CTACGGACGGACCCGCACCCAGGAAGGATTCGATGACTTCGCCAAGGAGTGGATCATGGGGCTCGACCACTTGGGCTACC
TGGAGAAGCTCGGCTGGCCGCGGATGCTGACCCTGAAGGCGAACACCGCGCTCAACTACTCCACCGGCGTGAAGAGGGGG
CAATAA

Upstream 100 bases:

>100_bases
CTCCATCTACGAAGGGACCAGCGAGATCCAGCGGGTGGTTATCTCGCGGGAAATTCTCAAGAATTTTAACCAATAGAAAT
TATCACATATGGAGGTATGT

Downstream 100 bases:

>100_bases
TATGGGCAGAGAGTATGCGAATCCGGAAGAATACGGCCTGGCCGACCTGCTGTGCTGCGCGGCGTCCCGCGAGGTGCAGG
ACAACGAAATCGTCTTCGCC

Product: coenzyme A transferase

Products: NA

Alternate protein names: GCT large subunit [H]

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MGTGKRITLQQAAEIIKDGSSLTFSGFTIWRRPMAIVFELIRQQRRGLHLIEVNGGPHTEFLVGAGCVDIWESCWVGHEL
YGKYGANLSRKVGNKEIIVEDYSHAEMMFRFAAGAAGAPYAVTQTSLGTDIHNPEYDMLGRAGKRDGKRIPKHKYLFTDD
PFYGAGPQVLVPAAKADIAIMCVQQVGEEGTVRVNGQYYSDPEAARTADITIVMAEEIVPEEYLRREADRNTITSFEVDY
IVECPYGAHPTGMFGRYDVDGAFLKDFYGRTRTQEGFDDFAKEWIMGLDHLGYLEKLGWPRMLTLKANTALNYSTGVKRG
Q

Sequences:

>Translated_321_residues
MGTGKRITLQQAAEIIKDGSSLTFSGFTIWRRPMAIVFELIRQQRRGLHLIEVNGGPHTEFLVGAGCVDIWESCWVGHEL
YGKYGANLSRKVGNKEIIVEDYSHAEMMFRFAAGAAGAPYAVTQTSLGTDIHNPEYDMLGRAGKRDGKRIPKHKYLFTDD
PFYGAGPQVLVPAAKADIAIMCVQQVGEEGTVRVNGQYYSDPEAARTADITIVMAEEIVPEEYLRREADRNTITSFEVDY
IVECPYGAHPTGMFGRYDVDGAFLKDFYGRTRTQEGFDDFAKEWIMGLDHLGYLEKLGWPRMLTLKANTALNYSTGVKRG
Q
>Mature_320_residues
GTGKRITLQQAAEIIKDGSSLTFSGFTIWRRPMAIVFELIRQQRRGLHLIEVNGGPHTEFLVGAGCVDIWESCWVGHELY
GKYGANLSRKVGNKEIIVEDYSHAEMMFRFAAGAAGAPYAVTQTSLGTDIHNPEYDMLGRAGKRDGKRIPKHKYLFTDDP
FYGAGPQVLVPAAKADIAIMCVQQVGEEGTVRVNGQYYSDPEAARTADITIVMAEEIVPEEYLRREADRNTITSFEVDYI
VECPYGAHPTGMFGRYDVDGAFLKDFYGRTRTQEGFDDFAKEWIMGLDHLGYLEKLGWPRMLTLKANTALNYSTGVKRGQ

Specific function: Catalyzes the transfer of the CoA moiety from acetyl-CoA to (R)-2-hydroxyglutarate and related compounds like glutaconate [H]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004165 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.12 [H]

Molecular weight: Translated: 35888; Mature: 35757

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTGKRITLQQAAEIIKDGSSLTFSGFTIWRRPMAIVFELIRQQRRGLHLIEVNGGPHTE
CCCCCEEEHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCE
FLVGAGCVDIWESCWVGHELYGKYGANLSRKVGNKEIIVEDYSHAEMMFRFAAGAAGAPY
EEECCCHHHHHHHHCCCHHHHHHHCCCHHHHCCCCEEEEECCHHHHHHHHHHCCCCCCCC
AVTQTSLGTDIHNPEYDMLGRAGKRDGKRIPKHKYLFTDDPFYGAGPQVLVPAAKADIAI
EEEECCCCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCCHH
MCVQQVGEEGTVRVNGQYYSDPEAARTADITIVMAEEIVPEEYLRREADRNTITSFEVDY
HHHHHCCCCCEEEECCEEECCCCCCCEEEEEEEEEHHHCCHHHHHHHCCCCCCEEEEEEE
IVECPYGAHPTGMFGRYDVDGAFLKDFYGRTRTQEGFDDFAKEWIMGLDHLGYLEKLGWP
EEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
RMLTLKANTALNYSTGVKRGQ
EEEEEECCCEEECCCCCCCCC
>Mature Secondary Structure 
GTGKRITLQQAAEIIKDGSSLTFSGFTIWRRPMAIVFELIRQQRRGLHLIEVNGGPHTE
CCCCEEEHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCE
FLVGAGCVDIWESCWVGHELYGKYGANLSRKVGNKEIIVEDYSHAEMMFRFAAGAAGAPY
EEECCCHHHHHHHHCCCHHHHHHHCCCHHHHCCCCEEEEECCHHHHHHHHHHCCCCCCCC
AVTQTSLGTDIHNPEYDMLGRAGKRDGKRIPKHKYLFTDDPFYGAGPQVLVPAAKADIAI
EEEECCCCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCCHH
MCVQQVGEEGTVRVNGQYYSDPEAARTADITIVMAEEIVPEEYLRREADRNTITSFEVDY
HHHHHCCCCCEEEECCEEECCCCCCCEEEEEEEEEHHHCCHHHHHHHCCCCCCEEEEEEE
IVECPYGAHPTGMFGRYDVDGAFLKDFYGRTRTQEGFDDFAKEWIMGLDHLGYLEKLGWP
EEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
RMLTLKANTALNYSTGVKRGQ
EEEEEECCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7957258; 9083111 [H]