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The map label for this gene is fabF [H]

Identifier: 78222905

GI number: 78222905

Start: 1902867

End: 1903907

Strand: Direct

Name: fabF [H]

Synonym: Gmet_1696

Alternate gene names: 78222905

Gene position: 1902867-1903907 (Clockwise)

Preceding gene: 78222904

Following gene: 78222906

Centisome position: 47.6

GC content: 65.03

Gene sequence:

>1041_bases
ATGAAACCTGTGACCCATGACATAGTCGTCACCGGCCTCGCTGCCATCTCTGCGGCCGGGGTTGGCCTCGAAACCCTTGC
CGCTGCGATCAGCGACGGACAGAGCCGCCTCCGTCCCGTTCCGGAAGACCTTGCCGGTGGAGGGCACCTGTGGGGGCCCG
CGGACGGATTTCGCGCCGCCGACTTCATGCCCCCCCTCAAGGCACGGAAGTTTGACCGCTGCAGCCTGATGGCCGTGGCT
GCCGCCGGCATGGCGCTGCGGGACGCCGTCCTCGACCTGAAGGGAGTCGATCCGACGCGGGTCGGCATCGTTTTGGGGTG
CGGGTTCGGCGGCATTGCCAACTCGGTCGAGTTCCTCAGCGGCTACTTCACCGGGGGGGTAGATGGCCTTTCACCGATGC
TCTTTCCCAACACGGTGGCGAATGCCGCTGCCAGTAATGCCTCCATCGAGCATGGCATCCAGGGGCCCAATGTCACCTTT
GTCCAGCGTTTCTGTTCGGCGGAGACAGCCCTGACGATGGGGTGCCGTTTCCTGGAAGAGGGGCGGGCGGACGTGATCAT
TGCCGGTGGTGTCGACGAGTTGAATGCCATGATGATCAGGGGATTCGACGCGATGAAGCAGCTTGGGAGCTACGCAGGGG
GATTCGGCGAAGGGTGCGGCCTGCTGGTTCTGGAACGTCGGGACCATGCCGAGCGACGCAGGGCGCCGGTACGGGGGAGG
ATTGCCGGTATCCGGTCGGTGGGGCTCATCCTTCCCGGTGCCGAGGACGAGGGGGTCGCCCGACTTCTTCCCGAGAACCT
CTCCCAGTACCGCATTTCCGTCTCCGGCACCGCTGACCTTTCTCCCCGGTTGATGGAACGGTTACCCGGTGCGCCTCAGC
TCCAACTGCATCGTCTGACCGGCCGGTCGCTGGCTATGGGTGGGCTTGCCCTTGCGGCCCTGCTCCTTACGCTTCGGGAG
GGGGAACAGGGCCTGCATCTGGCTGCTTCGCCGGAAGGCCCCTTCGTTGCCATCGAGATCAGCGGAGGCGCTCCTGTTTA
A

Upstream 100 bases:

>100_bases
TGGATTACTGCCACGACGGCCCACGCGCCAGCGGGGCAACCGTCGCGCTCTCCAACTCGTTTGCCTTTGGCGGCAACATC
ACCACCCTGGTGTTATCCCG

Downstream 100 bases:

>100_bases
TCCCAACCCCGAAGCATATCTCCCCCACCGCCGTCCTTTTCTCCTTCTCGACCGCATCGTGGCGCTCCAACCGGGCGAGA
CGGCCACGGCCGCCATCTCC

Product: Beta-ketoacyl synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKPVTHDIVVTGLAAISAAGVGLETLAAAISDGQSRLRPVPEDLAGGGHLWGPADGFRAADFMPPLKARKFDRCSLMAVA
AAGMALRDAVLDLKGVDPTRVGIVLGCGFGGIANSVEFLSGYFTGGVDGLSPMLFPNTVANAAASNASIEHGIQGPNVTF
VQRFCSAETALTMGCRFLEEGRADVIIAGGVDELNAMMIRGFDAMKQLGSYAGGFGEGCGLLVLERRDHAERRRAPVRGR
IAGIRSVGLILPGAEDEGVARLLPENLSQYRISVSGTADLSPRLMERLPGAPQLQLHRLTGRSLAMGGLALAALLLTLRE
GEQGLHLAASPEGPFVAIEISGGAPV

Sequences:

>Translated_346_residues
MKPVTHDIVVTGLAAISAAGVGLETLAAAISDGQSRLRPVPEDLAGGGHLWGPADGFRAADFMPPLKARKFDRCSLMAVA
AAGMALRDAVLDLKGVDPTRVGIVLGCGFGGIANSVEFLSGYFTGGVDGLSPMLFPNTVANAAASNASIEHGIQGPNVTF
VQRFCSAETALTMGCRFLEEGRADVIIAGGVDELNAMMIRGFDAMKQLGSYAGGFGEGCGLLVLERRDHAERRRAPVRGR
IAGIRSVGLILPGAEDEGVARLLPENLSQYRISVSGTADLSPRLMERLPGAPQLQLHRLTGRSLAMGGLALAALLLTLRE
GEQGLHLAASPEGPFVAIEISGGAPV
>Mature_346_residues
MKPVTHDIVVTGLAAISAAGVGLETLAAAISDGQSRLRPVPEDLAGGGHLWGPADGFRAADFMPPLKARKFDRCSLMAVA
AAGMALRDAVLDLKGVDPTRVGIVLGCGFGGIANSVEFLSGYFTGGVDGLSPMLFPNTVANAAASNASIEHGIQGPNVTF
VQRFCSAETALTMGCRFLEEGRADVIIAGGVDELNAMMIRGFDAMKQLGSYAGGFGEGCGLLVLERRDHAERRRAPVRGR
IAGIRSVGLILPGAEDEGVARLLPENLSQYRISVSGTADLSPRLMERLPGAPQLQLHRLTGRSLAMGGLALAALLLTLRE
GEQGLHLAASPEGPFVAIEISGGAPV

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=285, Percent_Identity=24.9122807017544, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI1787337, Length=256, Percent_Identity=27.34375, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 35873; Mature: 35873

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPVTHDIVVTGLAAISAAGVGLETLAAAISDGQSRLRPVPEDLAGGGHLWGPADGFRAA
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHCCCCCHHHCCCCCCCCCCCCCCCC
DFMPPLKARKFDRCSLMAVAAAGMALRDAVLDLKGVDPTRVGIVLGCGFGGIANSVEFLS
CCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHH
GYFTGGVDGLSPMLFPNTVANAAASNASIEHGIQGPNVTFVQRFCSAETALTMGCRFLEE
HHHCCCCCCCCCCCCCHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GRADVIIAGGVDELNAMMIRGFDAMKQLGSYAGGFGEGCGLLVLERRDHAERRRAPVRGR
CCCCEEEECCHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHCCCCHHH
IAGIRSVGLILPGAEDEGVARLLPENLSQYRISVSGTADLSPRLMERLPGAPQLQLHRLT
HHHHHEEEEEECCCCCCCHHHHHHHCHHHEEEEECCCCCCCHHHHHHCCCCCCEEEEECC
GRSLAMGGLALAALLLTLREGEQGLHLAASPEGPFVAIEISGGAPV
CCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCCCCC
>Mature Secondary Structure
MKPVTHDIVVTGLAAISAAGVGLETLAAAISDGQSRLRPVPEDLAGGGHLWGPADGFRAA
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHCCCCCHHHCCCCCCCCCCCCCCCC
DFMPPLKARKFDRCSLMAVAAAGMALRDAVLDLKGVDPTRVGIVLGCGFGGIANSVEFLS
CCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHH
GYFTGGVDGLSPMLFPNTVANAAASNASIEHGIQGPNVTFVQRFCSAETALTMGCRFLEE
HHHCCCCCCCCCCCCCHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GRADVIIAGGVDELNAMMIRGFDAMKQLGSYAGGFGEGCGLLVLERRDHAERRRAPVRGR
CCCCEEEECCHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHCCCCHHH
IAGIRSVGLILPGAEDEGVARLLPENLSQYRISVSGTADLSPRLMERLPGAPQLQLHRLT
HHHHHEEEEEECCCCCCCHHHHHHHCHHHEEEEECCCCCCCHHHHHHCCCCCCEEEEECC
GRSLAMGGLALAALLLTLREGEQGLHLAASPEGPFVAIEISGGAPV
CCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]