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The map label for this gene is bepF [H]

Identifier: 78222874

GI number: 78222874

Start: 1869273

End: 1870469

Strand: Reverse

Name: bepF [H]

Synonym: Gmet_1665

Alternate gene names: 78222874

Gene position: 1870469-1869273 (Counterclockwise)

Preceding gene: 78222875

Following gene: 78222873

Centisome position: 46.79

GC content: 59.4

Gene sequence:

>1197_bases
ATGTTTCGCGGAATGAAAACCACTTTCCAACCCTTACATTGCCTTGTGCTCTGGGTCCTGCCACTTCTCGCCCTTCTTCA
GGCCGGATGCAAGAAGCCCCCGCCGCCCCCTCCCCCGCCCCCGAAGGTGACCGTTTCTCACCCCCTGAAACGTGAAGTTA
CCGATTACCTGGAACTGACCGGCAACACCCAGGCCGTCAACTCTGTGCAGTTGGTCGCTCGTGTTCCCGGGTATCTTGAG
AAGGTCTTTTTCCGGGACGGGCAGATGGTCACCAATGGGCAACCGCTCTTTCAGCTACAGCGGAACACCTATGAGGCCGC
CCTCCGCCAGGCCGAAGGCCAGGTCATGGCGCTGAAATCGCAGCTTGAGTACGCCGAAGGTCAACTGATCCGCTACTCCA
ACCTGTTGCCCCATAAGGCCGCTACCCAGACTGACGTGGACAACTGGAGATACCAGCGGGACTCCGCCAGGGCTAACCTG
AAAGCCGCGGAGGCGAATCGGGACCTCGCAAGGCTCAATCTTGGCTACACCCTGGTCTCGGCCCCCTTTAGCGGACGGAT
AGATCGGAGACAGCAGGATCCGGGAAATCTGGTGGGCTCTGAAACGAACAACACCGTTCTTGCCCAACTCATCCAGATCG
ACCCCATTTACGTGTATTTCACGGTCAGCGACCTGGACCTGGCCCGGTTGCTCAAGACAAACCGTCTTCCCGGCGTTGCC
AAAACAGAAAAACGCCCGGTTTTTATCGCCCTTGCACAGGAAGAGGGTTATTCGCACAAGGGTTATGTCGATTTTGCCGC
CACAAGCCTCACCCCTACCACCGGAACGCTGCTGTTACGGGGCGTCTTCCGGAATCCGTCAGGAAGGATACTCCCCGGAT
TGTACGCGAAGGTCCGTCTCCCGCTGGAGAGAAGGGTCGCTCTCCTGACTCCCGACACGGCAATAAGAAGCGACCAGCAG
GGGTCGTACGTGCTGACCGTGAACGGCAAAAATACGGTGGAGCGGCGCGCCGTCAAGACAGGCCACCAGGAGGATTCCCT
GCGCGTGATCGAACAAGGCCTTGACGGAAGCGAATGGGTCATCGTCAAAGGACAGCTGAAAGCCCCCTCTGGAAGCCGTG
TAACCCCCGTACGGGAGGATGCGGAGCCTGCGTCTGCCCCTTCCCGCACCACCGCGGGACCGAAGGTCAAGCCGTGA

Upstream 100 bases:

>100_bases
GGGGCCGGACTGGTGACCGTTTTGCCGCGGCATCATGAATAGATCAGTACTGAACGGAGACATTCGATAGTCTGATGCGG
ACCAGGGAGGCAATGCGGCT

Downstream 100 bases:

>100_bases
TTTCCCAGTTCTTCATCGAACGTCCCATCTTCGCCAACGTCATCGCGCTGGTCACGGTCATCATCGGGCTGATCTTCCTG
AATCGCCTGCCAGTGGCCCA

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MFRGMKTTFQPLHCLVLWVLPLLALLQAGCKKPPPPPPPPPKVTVSHPLKREVTDYLELTGNTQAVNSVQLVARVPGYLE
KVFFRDGQMVTNGQPLFQLQRNTYEAALRQAEGQVMALKSQLEYAEGQLIRYSNLLPHKAATQTDVDNWRYQRDSARANL
KAAEANRDLARLNLGYTLVSAPFSGRIDRRQQDPGNLVGSETNNTVLAQLIQIDPIYVYFTVSDLDLARLLKTNRLPGVA
KTEKRPVFIALAQEEGYSHKGYVDFAATSLTPTTGTLLLRGVFRNPSGRILPGLYAKVRLPLERRVALLTPDTAIRSDQQ
GSYVLTVNGKNTVERRAVKTGHQEDSLRVIEQGLDGSEWVIVKGQLKAPSGSRVTPVREDAEPASAPSRTTAGPKVKP

Sequences:

>Translated_398_residues
MFRGMKTTFQPLHCLVLWVLPLLALLQAGCKKPPPPPPPPPKVTVSHPLKREVTDYLELTGNTQAVNSVQLVARVPGYLE
KVFFRDGQMVTNGQPLFQLQRNTYEAALRQAEGQVMALKSQLEYAEGQLIRYSNLLPHKAATQTDVDNWRYQRDSARANL
KAAEANRDLARLNLGYTLVSAPFSGRIDRRQQDPGNLVGSETNNTVLAQLIQIDPIYVYFTVSDLDLARLLKTNRLPGVA
KTEKRPVFIALAQEEGYSHKGYVDFAATSLTPTTGTLLLRGVFRNPSGRILPGLYAKVRLPLERRVALLTPDTAIRSDQQ
GSYVLTVNGKNTVERRAVKTGHQEDSLRVIEQGLDGSEWVIVKGQLKAPSGSRVTPVREDAEPASAPSRTTAGPKVKP
>Mature_398_residues
MFRGMKTTFQPLHCLVLWVLPLLALLQAGCKKPPPPPPPPPKVTVSHPLKREVTDYLELTGNTQAVNSVQLVARVPGYLE
KVFFRDGQMVTNGQPLFQLQRNTYEAALRQAEGQVMALKSQLEYAEGQLIRYSNLLPHKAATQTDVDNWRYQRDSARANL
KAAEANRDLARLNLGYTLVSAPFSGRIDRRQQDPGNLVGSETNNTVLAQLIQIDPIYVYFTVSDLDLARLLKTNRLPGVA
KTEKRPVFIALAQEEGYSHKGYVDFAATSLTPTTGTLLLRGVFRNPSGRILPGLYAKVRLPLERRVALLTPDTAIRSDQQ
GSYVLTVNGKNTVERRAVKTGHQEDSLRVIEQGLDGSEWVIVKGQLKAPSGSRVTPVREDAEPASAPSRTTAGPKVKP

Specific function: May contribute to resistance to some drugs, such as deoxycholate, sodium dodecyl sulfate and nalidixic acid, in the absence of BepD and BepE [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789665, Length=369, Percent_Identity=32.7913279132791, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI87082036, Length=363, Percent_Identity=26.4462809917355, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786668, Length=372, Percent_Identity=29.3010752688172, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1789929, Length=335, Percent_Identity=27.4626865671642, Blast_Score=112, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43991; Mature: 43991

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRGMKTTFQPLHCLVLWVLPLLALLQAGCKKPPPPPPPPPKVTVSHPLKREVTDYLELT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHHHHC
GNTQAVNSVQLVARVPGYLEKVFFRDGQMVTNGQPLFQLQRNTYEAALRQAEGQVMALKS
CCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEHHHHHHHHHHHHCCCCEEEHHH
QLEYAEGQLIRYSNLLPHKAATQTDVDNWRYQRDSARANLKAAEANRDLARLNLGYTLVS
HHHHHCCCEEEECCCCCCCCCCCCCCHHHEECCCHHHCCCCHHHCCCCCEEEECCEEEEE
APFSGRIDRRQQDPGNLVGSETNNTVLAQLIQIDPIYVYFTVSDLDLARLLKTNRLPGVA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEEECCHHHHHHHHHCCCCCCC
KTEKRPVFIALAQEEGYSHKGYVDFAATSLTPTTGTLLLRGVFRNPSGRILPGLYAKVRL
CCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCHHHHHEEHHHCCCCCCCCCCCCEEEEC
PLERRVALLTPDTAIRSDQQGSYVLTVNGKNTVERRAVKTGHQEDSLRVIEQGLDGSEWV
CHHHCEEEECCCHHHCCCCCCCEEEEECCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCEE
IVKGQLKAPSGSRVTPVREDAEPASAPSRTTAGPKVKP
EEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFRGMKTTFQPLHCLVLWVLPLLALLQAGCKKPPPPPPPPPKVTVSHPLKREVTDYLELT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHHHHC
GNTQAVNSVQLVARVPGYLEKVFFRDGQMVTNGQPLFQLQRNTYEAALRQAEGQVMALKS
CCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEHHHHHHHHHHHHCCCCEEEHHH
QLEYAEGQLIRYSNLLPHKAATQTDVDNWRYQRDSARANLKAAEANRDLARLNLGYTLVS
HHHHHCCCEEEECCCCCCCCCCCCCCHHHEECCCHHHCCCCHHHCCCCCEEEECCEEEEE
APFSGRIDRRQQDPGNLVGSETNNTVLAQLIQIDPIYVYFTVSDLDLARLLKTNRLPGVA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEEECCHHHHHHHHHCCCCCCC
KTEKRPVFIALAQEEGYSHKGYVDFAATSLTPTTGTLLLRGVFRNPSGRILPGLYAKVRL
CCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCHHHHHEEHHHCCCCCCCCCCCCEEEEC
PLERRVALLTPDTAIRSDQQGSYVLTVNGKNTVERRAVKTGHQEDSLRVIEQGLDGSEWV
CHHHCEEEECCCHHHCCCCCCCEEEEECCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCEE
IVKGQLKAPSGSRVTPVREDAEPASAPSRTTAGPKVKP
EEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]