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The map label for this gene is 78222804

Identifier: 78222804

GI number: 78222804

Start: 1796377

End: 1797483

Strand: Direct

Name: 78222804

Synonym: Gmet_1594

Alternate gene names: NA

Gene position: 1796377-1797483 (Clockwise)

Preceding gene: 78222803

Following gene: 78222805

Centisome position: 44.94

GC content: 52.57

Gene sequence:

>1107_bases
ATGTTCGATCCGCGCGTCCGTCAACTTGCCGAAGTGCTCGTTACTTACTCGACCCGGGTAAAAAAGGGGGACGTGGTCCT
CATCAATGCCAGCGGCACCGATTGCCTTCCCCTGGTGAAGGAGCTTTATTCCCTCTGTCTGGCCCGGGGGGCAAAGTATG
TTGAGTATTCTTTCCATATCCCCGAGATAGACCGCCATTTCTACAACACTGCCACTAAGTCGCAGCTCTCCTTCTTTCCC
CAGCACAAGCTGGATTTCATGAAGCAGGTCAACGTCTTTATTTCCATCTCCGGCTCCCCTAATTCCATGGTTATGGCTCA
GGCTAACCAGAAAAACATGATTGCCTGGTCGAAGGTGACCCGCCCCATCGTTGACTGGCGAGTCAAAAATACCCGCTGGG
TAATTACCCGTTATCCTACGCATGGGGCTGCCCAGGAAGCGAAGATGAGTCTTGAAGAGTATGAAGAATATCTTTTCGCC
GCCTGCTGCATCGATTGGGAGGCTGAATCGCGCAAACAGGAGAAGTTGAAGCGCCTCATGGACAAGGCCGACACGGTACG
GATCAAAGCGTCTGACACGGATCTCTCGTTCAGCATCAGAGGGCTTGACGGCATAAAGTGTGACGGGCGTTTCAATATCC
CTGACGGAGAAGTTTTTACCGCACCTGTCCGGGATTCTGTCGAAGGACACATCACATACAACTGCCCGACTATCTACCAA
GGTAAGGAATTCAACGGCGTCCGTCTCGAATTTGCGAAGGGGCGGATTGTGAAGGCCTCGGCGCCCGGCATGGACGATGA
GCTTAACCGTATCCTCGATACCGATGAGGGCGCACGCTTTATCGGAGAATTTGCCATTGGTGTCAATCCGAACATCCGCG
TGCCAATGAGGAATATCCTCTTTGACGAGAAGATCTTCGGCTCCATACATTTTACTCCGGGGCAATGTTATGACGAGTGC
GACAATGGCAACCGTTCGGCTGTCCACTGGGACATGGTGAAGCTCCTCAAGGGTGACGGGGAAATCTGGTTTGACAATCA
CCTTATCCAGAAGGATGGCCTCTTTGTGCACAAAGACCTCGTTTCCCTTAATCCGGCGCGAGAGTAG

Upstream 100 bases:

>100_bases
CTTTGCCCGTGCTGAACTGGTTGAGGTGGATGAACTCGACGAGACAGCGCGGGGCGAGGGAGGATTTGGCCATACCGGCC
GATGAAAGGAACTGAGTCCA

Downstream 100 bases:

>100_bases
CTCCCATGCTCCTTGACATTAACCCCCAGAATCCTCAACCGAGACTCGTCGCACAGGTGGTCAAAATCCTCAAGGATGGC
GGCATCATTGCCTATCCGAC

Product: peptidase M29, aminopeptidase II

Products: NA

Alternate protein names: Aminopeptidase II; AP-II [H]

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MFDPRVRQLAEVLVTYSTRVKKGDVVLINASGTDCLPLVKELYSLCLARGAKYVEYSFHIPEIDRHFYNTATKSQLSFFP
QHKLDFMKQVNVFISISGSPNSMVMAQANQKNMIAWSKVTRPIVDWRVKNTRWVITRYPTHGAAQEAKMSLEEYEEYLFA
ACCIDWEAESRKQEKLKRLMDKADTVRIKASDTDLSFSIRGLDGIKCDGRFNIPDGEVFTAPVRDSVEGHITYNCPTIYQ
GKEFNGVRLEFAKGRIVKASAPGMDDELNRILDTDEGARFIGEFAIGVNPNIRVPMRNILFDEKIFGSIHFTPGQCYDEC
DNGNRSAVHWDMVKLLKGDGEIWFDNHLIQKDGLFVHKDLVSLNPARE

Sequences:

>Translated_368_residues
MFDPRVRQLAEVLVTYSTRVKKGDVVLINASGTDCLPLVKELYSLCLARGAKYVEYSFHIPEIDRHFYNTATKSQLSFFP
QHKLDFMKQVNVFISISGSPNSMVMAQANQKNMIAWSKVTRPIVDWRVKNTRWVITRYPTHGAAQEAKMSLEEYEEYLFA
ACCIDWEAESRKQEKLKRLMDKADTVRIKASDTDLSFSIRGLDGIKCDGRFNIPDGEVFTAPVRDSVEGHITYNCPTIYQ
GKEFNGVRLEFAKGRIVKASAPGMDDELNRILDTDEGARFIGEFAIGVNPNIRVPMRNILFDEKIFGSIHFTPGQCYDEC
DNGNRSAVHWDMVKLLKGDGEIWFDNHLIQKDGLFVHKDLVSLNPARE
>Mature_368_residues
MFDPRVRQLAEVLVTYSTRVKKGDVVLINASGTDCLPLVKELYSLCLARGAKYVEYSFHIPEIDRHFYNTATKSQLSFFP
QHKLDFMKQVNVFISISGSPNSMVMAQANQKNMIAWSKVTRPIVDWRVKNTRWVITRYPTHGAAQEAKMSLEEYEEYLFA
ACCIDWEAESRKQEKLKRLMDKADTVRIKASDTDLSFSIRGLDGIKCDGRFNIPDGEVFTAPVRDSVEGHITYNCPTIYQ
GKEFNGVRLEFAKGRIVKASAPGMDDELNRILDTDEGARFIGEFAIGVNPNIRVPMRNILFDEKIFGSIHFTPGQCYDEC
DNGNRSAVHWDMVKLLKGDGEIWFDNHLIQKDGLFVHKDLVSLNPARE

Specific function: Broad specificity metal-dependent exopeptidase, releasing all N-terminal amino acids [H]

COG id: COG2309

COG function: function code E; Leucyl aminopeptidase (aminopeptidase T)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M29 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000787 [H]

Pfam domain/function: PF02073 Peptidase_M29 [H]

EC number: NA

Molecular weight: Translated: 41951; Mature: 41951

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDPRVRQLAEVLVTYSTRVKKGDVVLINASGTDCLPLVKELYSLCLARGAKYVEYSFHI
CCCHHHHHHHHHHHHHHCEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECC
PEIDRHFYNTATKSQLSFFPQHKLDFMKQVNVFISISGSPNSMVMAQANQKNMIAWSKVT
CHHHHHHHCCCCHHHHHHCCHHHHHHHHCCEEEEEECCCCCCEEEEECCCCCEEEHHHHC
RPIVDWRVKNTRWVITRYPTHGAAQEAKMSLEEYEEYLFAACCIDWEAESRKQEKLKRLM
CCHHCEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHH
DKADTVRIKASDTDLSFSIRGLDGIKCDGRFNIPDGEVFTAPVRDSVEGHITYNCPTIYQ
CCCCEEEEEECCCCEEEEEECCCCEEECCEECCCCCCEEECCCCCCCCEEEEECCCEEEC
GKEFNGVRLEFAKGRIVKASAPGMDDELNRILDTDEGARFIGEFAIGVNPNIRVPMRNIL
CCCCCCEEEEEECCEEEEECCCCCCHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHH
FDEKIFGSIHFTPGQCYDECDNGNRSAVHWDMVKLLKGDGEIWFDNHLIQKDGLFVHKDL
CCHHHEEEEECCCCCHHHHHCCCCCCEEHHHHHHHHCCCCCEEECCEEECCCCEEEEEHH
VSLNPARE
HCCCCCCC
>Mature Secondary Structure
MFDPRVRQLAEVLVTYSTRVKKGDVVLINASGTDCLPLVKELYSLCLARGAKYVEYSFHI
CCCHHHHHHHHHHHHHHCEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECC
PEIDRHFYNTATKSQLSFFPQHKLDFMKQVNVFISISGSPNSMVMAQANQKNMIAWSKVT
CHHHHHHHCCCCHHHHHHCCHHHHHHHHCCEEEEEECCCCCCEEEEECCCCCEEEHHHHC
RPIVDWRVKNTRWVITRYPTHGAAQEAKMSLEEYEEYLFAACCIDWEAESRKQEKLKRLM
CCHHCEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHH
DKADTVRIKASDTDLSFSIRGLDGIKCDGRFNIPDGEVFTAPVRDSVEGHITYNCPTIYQ
CCCCEEEEEECCCCEEEEEECCCCEEECCEECCCCCCEEECCCCCCCCEEEEECCCEEEC
GKEFNGVRLEFAKGRIVKASAPGMDDELNRILDTDEGARFIGEFAIGVNPNIRVPMRNIL
CCCCCCEEEEEECCEEEEECCCCCCHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHH
FDEKIFGSIHFTPGQCYDECDNGNRSAVHWDMVKLLKGDGEIWFDNHLIQKDGLFVHKDL
CCHHHEEEEECCCCCHHHHHCCCCCCEEHHHHHHHHCCCCCEEECCEEECCCCEEEEEHH
VSLNPARE
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9362117; 938681 [H]