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The map label for this gene is czcC [H]

Identifier: 78222761

GI number: 78222761

Start: 1756046

End: 1757326

Strand: Reverse

Name: czcC [H]

Synonym: Gmet_1549

Alternate gene names: 78222761

Gene position: 1757326-1756046 (Counterclockwise)

Preceding gene: 78222762

Following gene: 78222760

Centisome position: 43.96

GC content: 59.72

Gene sequence:

>1281_bases
ATGAAATCACGTCTCGCAATCGGGTTCATGCTTCTCGCGGTGCTGGCGCTTCCGTACCAGGCACCGGCCGAGGAAACAAA
ACCATCCGAAAATCTCCCTCAGCTTGTCGATGCTGCCCTCGCCAACAATCCCGAGGTGAAGGCGTCCGAGGCCCGTTGGG
AGATGTTCCGCAACCGCGTGGCCCAAGCGGGTGCCCTTGACGATCCGATGCTCATGCTCAAGATGCAGAGCTTCCTGATC
CGCGATCCCTTCAATTCCCGGCGTGATCCCATGAGCCAGCGGGTGATCGGCATCTCGCAGCAACTCCCCTTCTGGGGGAA
GCGGGACCTGAAGGCCGAGGTGGCGTCGAGGGAGGCCGAGGCGCTCAAGTGGCAGGTGGCGGAGCGGAAGTTGGAACTGG
CCCGGATGGTGAAGGAGACCTGGTACCAAATCTTTCTGACCGACAAGGAGTTGCAGATCGTCGAGAAGAATATCCGGATC
ATGGATGACTTCATCGCCCTTGCCGAAACGAAATACTCCGTGGGCCAGGGGGCCCAGCAGGACGTCTTCAAGGCCCAGGT
TGAACGTTCGAAGATGGTCGACATGAAGATATCCCTGGAACAGCAGCGAAAGAGCCTCCAGGCCACCCTGAACACCCTGC
TCTACCGCCCCGCCGAAACGCCGGTGGGAAAAGTTGCCGACTTCGAACTGAAGCCCTTTACCTGGTCCCCCGACCAACTC
CGCTCCATGGCGCAGGAGAACCGGCCGCTGGTCAAGAGTCTGCGCGCCGAGATCGAGAAGGGTGAAGCCGGACACCGTCT
GGCGGAAAAAGAGTATTTTCCTGACGTTAATCTCTCCTTCGAATATATGCAGCGGGATCCCATCAATGACATGGAGGCTG
GGTACGACATGTACAGCGCTGGCCTCACCTTCAATCTCCCGATCCAGCGGGAACGGCGCCATGCCATGGTCCGGGAGTCG
TCGGCCGAGATCGCCATGGCGACGGCAGAATTGAATACCTTGAACAACAGCATCAATCTCGGCATCGCCGACAGCCTGGC
CCAGCTGGAGCGGCGTGAGAAGCTCGCCAAGCTCTACCGCACCGGCATCATCCCCCAGGCGGAGCAGTCGCTGGAATCCG
CCACCATCGGCTACCGGGTAAACAAGGTCGACTTCCTTACGCTCCTCGACAACCGGCTGACCCTCTTCAACTACGAACGG
GACTATTACGAATCCCTGGCCGAGTACCAGATGCGCCTCGCCCAGCTTGAGGCCCTGGTCGGCAAGGAATTGCAGGAGTA
G

Upstream 100 bases:

>100_bases
AACAAGCGGCACAAGTTGAATATAAGCCGTAAAATCAGCCAATTTGCTTTTGGCACGGCAAATGGATAGTCATAACTATC
TACAACCTCCAGGAGACCCC

Downstream 100 bases:

>100_bases
TGGGCTTTCCCGGCGTGCGCGCCCTGTAGATGCTATGCATTGAACTATTCTCCATAAACCGCGAGGTACGATCATGAAAT
TGAGTGCAAAGGTAGCAGTT

Product: Outer membrane efflux protein

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MKSRLAIGFMLLAVLALPYQAPAEETKPSENLPQLVDAALANNPEVKASEARWEMFRNRVAQAGALDDPMLMLKMQSFLI
RDPFNSRRDPMSQRVIGISQQLPFWGKRDLKAEVASREAEALKWQVAERKLELARMVKETWYQIFLTDKELQIVEKNIRI
MDDFIALAETKYSVGQGAQQDVFKAQVERSKMVDMKISLEQQRKSLQATLNTLLYRPAETPVGKVADFELKPFTWSPDQL
RSMAQENRPLVKSLRAEIEKGEAGHRLAEKEYFPDVNLSFEYMQRDPINDMEAGYDMYSAGLTFNLPIQRERRHAMVRES
SAEIAMATAELNTLNNSINLGIADSLAQLERREKLAKLYRTGIIPQAEQSLESATIGYRVNKVDFLTLLDNRLTLFNYER
DYYESLAEYQMRLAQLEALVGKELQE

Sequences:

>Translated_426_residues
MKSRLAIGFMLLAVLALPYQAPAEETKPSENLPQLVDAALANNPEVKASEARWEMFRNRVAQAGALDDPMLMLKMQSFLI
RDPFNSRRDPMSQRVIGISQQLPFWGKRDLKAEVASREAEALKWQVAERKLELARMVKETWYQIFLTDKELQIVEKNIRI
MDDFIALAETKYSVGQGAQQDVFKAQVERSKMVDMKISLEQQRKSLQATLNTLLYRPAETPVGKVADFELKPFTWSPDQL
RSMAQENRPLVKSLRAEIEKGEAGHRLAEKEYFPDVNLSFEYMQRDPINDMEAGYDMYSAGLTFNLPIQRERRHAMVRES
SAEIAMATAELNTLNNSINLGIADSLAQLERREKLAKLYRTGIIPQAEQSLESATIGYRVNKVDFLTLLDNRLTLFNYER
DYYESLAEYQMRLAQLEALVGKELQE
>Mature_426_residues
MKSRLAIGFMLLAVLALPYQAPAEETKPSENLPQLVDAALANNPEVKASEARWEMFRNRVAQAGALDDPMLMLKMQSFLI
RDPFNSRRDPMSQRVIGISQQLPFWGKRDLKAEVASREAEALKWQVAERKLELARMVKETWYQIFLTDKELQIVEKNIRI
MDDFIALAETKYSVGQGAQQDVFKAQVERSKMVDMKISLEQQRKSLQATLNTLLYRPAETPVGKVADFELKPFTWSPDQL
RSMAQENRPLVKSLRAEIEKGEAGHRLAEKEYFPDVNLSFEYMQRDPINDMEAGYDMYSAGLTFNLPIQRERRHAMVRES
SAEIAMATAELNTLNNSINLGIADSLAQLERREKLAKLYRTGIIPQAEQSLESATIGYRVNKVDFLTLLDNRLTLFNYER
DYYESLAEYQMRLAQLEALVGKELQE

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 48916; Mature: 48916

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSRLAIGFMLLAVLALPYQAPAEETKPSENLPQLVDAALANNPEVKASEARWEMFRNRV
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
AQAGALDDPMLMLKMQSFLIRDPFNSRRDPMSQRVIGISQQLPFWGKRDLKAEVASREAE
HHCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
ALKWQVAERKLELARMVKETWYQIFLTDKELQIVEKNIRIMDDFIALAETKYSVGQGAQQ
HHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
DVFKAQVERSKMVDMKISLEQQRKSLQATLNTLLYRPAETPVGKVADFELKPFTWSPDQL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCHHHH
RSMAQENRPLVKSLRAEIEKGEAGHRLAEKEYFPDVNLSFEYMQRDPINDMEAGYDMYSA
HHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHCCCCCHHHHCCHHHHC
GLTFNLPIQRERRHAMVRESSAEIAMATAELNTLNNSINLGIADSLAQLERREKLAKLYR
CEEEECCCHHHHHHHHHHCCCCCEEEEHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
TGIIPQAEQSLESATIGYRVNKVDFLTLLDNRLTLFNYERDYYESLAEYQMRLAQLEALV
HCCCCHHHHHHHHHHHCEEECCEEEEHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHH
GKELQE
HHHHCC
>Mature Secondary Structure
MKSRLAIGFMLLAVLALPYQAPAEETKPSENLPQLVDAALANNPEVKASEARWEMFRNRV
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
AQAGALDDPMLMLKMQSFLIRDPFNSRRDPMSQRVIGISQQLPFWGKRDLKAEVASREAE
HHCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
ALKWQVAERKLELARMVKETWYQIFLTDKELQIVEKNIRIMDDFIALAETKYSVGQGAQQ
HHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
DVFKAQVERSKMVDMKISLEQQRKSLQATLNTLLYRPAETPVGKVADFELKPFTWSPDQL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCHHHH
RSMAQENRPLVKSLRAEIEKGEAGHRLAEKEYFPDVNLSFEYMQRDPINDMEAGYDMYSA
HHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHCCCCCHHHHCCHHHHC
GLTFNLPIQRERRHAMVRESSAEIAMATAELNTLNNSINLGIADSLAQLERREKLAKLYR
CEEEECCCHHHHHHHHHHCCCCCEEEEHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
TGIIPQAEQSLESATIGYRVNKVDFLTLLDNRLTLFNYERDYYESLAEYQMRLAQLEALV
HCCCCHHHHHHHHHHHCEEECCEEEEHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHH
GKELQE
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]