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The map label for this gene is 78222745

Identifier: 78222745

GI number: 78222745

Start: 1735571

End: 1737028

Strand: Reverse

Name: 78222745

Synonym: Gmet_1533

Alternate gene names: NA

Gene position: 1737028-1735571 (Counterclockwise)

Preceding gene: 78222746

Following gene: 78222732

Centisome position: 43.45

GC content: 55.62

Gene sequence:

>1458_bases
ATGAATCCGGCAACCAGTTGGGACAGAACCGTTGATGTGGTCGTCATCGGCTATGGCGGCGCCGGAGCGACGGCGGCCAT
TGCCGCCCACGATGCCGGGGCCGCCACACTGGTTCTCGAAAGCACCCCCCAAGGGGGAGGGAATACCCTGGTCTCTTTCG
GCGGGTTCATCAGCCATAACGACCCAATCAAAGCGCTTGCGTATGTCAGAGCGCTTTTTGATTCTTCCCATTCGGATAGA
GATGATCGATTGTTGCGGGTTTTTGTCGAAGAATCGGCAAAAACTCCCGACTGGCTTAAAACATTAGACAATGAAGTTGC
TTTTCAAACCTATGGCGGCGCCGGCTATCCTCAACTTGCCGGCGCCGAGGCGATCATTAGATATGTCGTAAAAGGCGCTA
ACCGGGGAACAACGGCCTTTGCCCGGAATCTATGGCAGCTGCTCTCCCAGGCCGTAGAACGCCACAGGAATATCCCGGTT
CTGACCCGAACTCCGGCGAAGCGCCTTGTTACCGGTGGTAACGGTGAAGTAACCGGAGTTATTGCCCAGTCTAAAGGGGA
TGAAATTGCGATTCAGGCAAGACGTGGCGTCATCCTTACGAGCGGCGGATACGAATTCGACCCGATAATGCTCAAAAACA
GCGTCAAAGGAAGTCCCCTTTACTCACTGGGACATCCCGGCAACCGGGGGGACGGGCTTCGCATGGCACAAAAAGTCGGC
GCAGCTTTATGGCACATGAACGGCGTCTCCTGCGCCTTCGGATTCAAGGCGCCTGAGTTTGACTCAGCGCTGTTGATGTC
CATCGGCACCACCGGCCAGATATTTGTCGACAGGAACGGCAAACGCTTTGTTAACGAAAGCGCCGTGGAACGTCAGGCCG
GTTTATTGGCGGTAGATTACTTCGACAGCCATGCCCTTTCCTATCCTCGTATCCCTTTTTACCTGATTTTTGATGAAAAT
AAGCGCAAGCGGGAACCGGTTTCCGGCTTGATCGGTCTCGGCTCTGCCGGCAGCCGCTACTCCTGGAGCAAAGACAATCG
TACAGAGATCGACAACGGCTGGATCGTGCAGGCTGAGACCATAGCCGACCTGGCCCGGCAACTGGGAATCTCCGGTTTGA
CCCTGCGTGATACCATTAAACAGTGGAATGCATCCGTACGGGCGGGAAAGGACACGCTCTTCGGGCGCGAGATTAAGGAA
AATAGTGATCTGGCCATGATCCATACCGGGCCGTTTTATGCCATGGAAATTTATCCCTCGCTGGCTAACACCCAAGGCGG
ACCACGGCGCAATGAACGGGCACAGATCGTCGATCCCTTCGGCGATCCGATACCGGGATTGTACGGAGCCGGAGAACTCG
GTTCCCTCTGGGGATTGGTTTATCAGGGTGGGGGCAATATTGCCGAATGTCTGGCCTTTGGGAGAATTGCCGGTGTGAGT
GCGGCGGCAGGCAGGTGA

Upstream 100 bases:

>100_bases
TTCTAAAGCGGATCAGCCATGGCAGGCTGGAGCAAAACTTGGAAATGGAGCAAACACTGTTCCGAATCATTTTACCGATT
AGAGGTCAAGCGGGAGCGGT

Downstream 100 bases:

>100_bases
AATGCCGCAGATTCTGGATTTGTCAGCAATCTGCGGCATTTCACTGCCTTAGTCCTTAGTGATTGTTGAAAGCCTTCATT
AGTGCAGGCGGGCGAGCACC

Product: fumarate reductase/succinate dehydrogenase flavoprotein-like

Products: NA

Alternate protein names: Flavocytochrome c; FL cyt [H]

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MNPATSWDRTVDVVVIGYGGAGATAAIAAHDAGAATLVLESTPQGGGNTLVSFGGFISHNDPIKALAYVRALFDSSHSDR
DDRLLRVFVEESAKTPDWLKTLDNEVAFQTYGGAGYPQLAGAEAIIRYVVKGANRGTTAFARNLWQLLSQAVERHRNIPV
LTRTPAKRLVTGGNGEVTGVIAQSKGDEIAIQARRGVILTSGGYEFDPIMLKNSVKGSPLYSLGHPGNRGDGLRMAQKVG
AALWHMNGVSCAFGFKAPEFDSALLMSIGTTGQIFVDRNGKRFVNESAVERQAGLLAVDYFDSHALSYPRIPFYLIFDEN
KRKREPVSGLIGLGSAGSRYSWSKDNRTEIDNGWIVQAETIADLARQLGISGLTLRDTIKQWNASVRAGKDTLFGREIKE
NSDLAMIHTGPFYAMEIYPSLANTQGGPRRNERAQIVDPFGDPIPGLYGAGELGSLWGLVYQGGGNIAECLAFGRIAGVS
AAAGR

Sequences:

>Translated_485_residues
MNPATSWDRTVDVVVIGYGGAGATAAIAAHDAGAATLVLESTPQGGGNTLVSFGGFISHNDPIKALAYVRALFDSSHSDR
DDRLLRVFVEESAKTPDWLKTLDNEVAFQTYGGAGYPQLAGAEAIIRYVVKGANRGTTAFARNLWQLLSQAVERHRNIPV
LTRTPAKRLVTGGNGEVTGVIAQSKGDEIAIQARRGVILTSGGYEFDPIMLKNSVKGSPLYSLGHPGNRGDGLRMAQKVG
AALWHMNGVSCAFGFKAPEFDSALLMSIGTTGQIFVDRNGKRFVNESAVERQAGLLAVDYFDSHALSYPRIPFYLIFDEN
KRKREPVSGLIGLGSAGSRYSWSKDNRTEIDNGWIVQAETIADLARQLGISGLTLRDTIKQWNASVRAGKDTLFGREIKE
NSDLAMIHTGPFYAMEIYPSLANTQGGPRRNERAQIVDPFGDPIPGLYGAGELGSLWGLVYQGGGNIAECLAFGRIAGVS
AAAGR
>Mature_485_residues
MNPATSWDRTVDVVVIGYGGAGATAAIAAHDAGAATLVLESTPQGGGNTLVSFGGFISHNDPIKALAYVRALFDSSHSDR
DDRLLRVFVEESAKTPDWLKTLDNEVAFQTYGGAGYPQLAGAEAIIRYVVKGANRGTTAFARNLWQLLSQAVERHRNIPV
LTRTPAKRLVTGGNGEVTGVIAQSKGDEIAIQARRGVILTSGGYEFDPIMLKNSVKGSPLYSLGHPGNRGDGLRMAQKVG
AALWHMNGVSCAFGFKAPEFDSALLMSIGTTGQIFVDRNGKRFVNESAVERQAGLLAVDYFDSHALSYPRIPFYLIFDEN
KRKREPVSGLIGLGSAGSRYSWSKDNRTEIDNGWIVQAETIADLARQLGISGLTLRDTIKQWNASVRAGKDTLFGREIKE
NSDLAMIHTGPFYAMEIYPSLANTQGGPRRNERAQIVDPFGDPIPGLYGAGELGSLWGLVYQGGGNIAECLAFGRIAGVS
AAAGR

Specific function: Catalyzes fumarate reduction using artificial electron donors such as methyl viologen. The physiological reductant is unknown, but evidence indicates that flavocytochrome c participates in electron transfer from formate to fumarate and possibly also to tr

COG id: COG1053

COG function: function code C; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI71986328, Length=445, Percent_Identity=24.7191011235955, Blast_Score=95, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR010960
- InterPro:   IPR011031
- InterPro:   IPR012286 [H]

Pfam domain/function: PF00890 FAD_binding_2 [H]

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 52011; Mature: 52011

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPATSWDRTVDVVVIGYGGAGATAAIAAHDAGAATLVLESTPQGGGNTLVSFGGFISHN
CCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCCEEEEEECCCCCCCCEEEEECCCCCCC
DPIKALAYVRALFDSSHSDRDDRLLRVFVEESAKTPDWLKTLDNEVAFQTYGGAGYPQLA
CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCEEEEECCCCCCCCCC
GAEAIIRYVVKGANRGTTAFARNLWQLLSQAVERHRNIPVLTRTPAKRLVTGGNGEVTGV
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHEEECCCCEEEEE
IAQSKGDEIAIQARRGVILTSGGYEFDPIMLKNSVKGSPLYSLGHPGNRGDGLRMAQKVG
EEECCCCEEEEEEECCEEEECCCCEECCEEEECCCCCCCEEECCCCCCCCCHHHHHHHHH
AALWHMNGVSCAFGFKAPEFDSALLMSIGTTGQIFVDRNGKRFVNESAVERQAGLLAVDY
HHHHCCCCCEEEECCCCCCCCCCEEEEECCCCEEEEECCCCHHHHHHHHHHHCCEEEEEE
FDSHALSYPRIPFYLIFDENKRKREPVSGLIGLGSAGSRYSWSKDNRTEIDNGWIVQAET
CCCCCCCCCCCCEEEEECCCCCCCCCCHHEEECCCCCCCCCCCCCCCCCCCCCEEEEHHH
IADLARQLGISGLTLRDTIKQWNASVRAGKDTLFGREIKENSDLAMIHTGPFYAMEIYPS
HHHHHHHHCCCCCCHHHHHHHHCCHHCCCCHHHCCCHHCCCCCEEEEECCCEEEEEEECH
LANTQGGPRRNERAQIVDPFGDPIPGLYGAGELGSLWGLVYQGGGNIAECLAFGRIAGVS
HHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHEEEEEECCCCHHHHHHHHHHCCCC
AAAGR
CCCCC
>Mature Secondary Structure
MNPATSWDRTVDVVVIGYGGAGATAAIAAHDAGAATLVLESTPQGGGNTLVSFGGFISHN
CCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCCEEEEEECCCCCCCCEEEEECCCCCCC
DPIKALAYVRALFDSSHSDRDDRLLRVFVEESAKTPDWLKTLDNEVAFQTYGGAGYPQLA
CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCEEEEECCCCCCCCCC
GAEAIIRYVVKGANRGTTAFARNLWQLLSQAVERHRNIPVLTRTPAKRLVTGGNGEVTGV
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHEEECCCCEEEEE
IAQSKGDEIAIQARRGVILTSGGYEFDPIMLKNSVKGSPLYSLGHPGNRGDGLRMAQKVG
EEECCCCEEEEEEECCEEEECCCCEECCEEEECCCCCCCEEECCCCCCCCCHHHHHHHHH
AALWHMNGVSCAFGFKAPEFDSALLMSIGTTGQIFVDRNGKRFVNESAVERQAGLLAVDY
HHHHCCCCCEEEECCCCCCCCCCEEEEECCCCEEEEECCCCHHHHHHHHHHHCCEEEEEE
FDSHALSYPRIPFYLIFDENKRKREPVSGLIGLGSAGSRYSWSKDNRTEIDNGWIVQAET
CCCCCCCCCCCCEEEEECCCCCCCCCCHHEEECCCCCCCCCCCCCCCCCCCCCEEEEHHH
IADLARQLGISGLTLRDTIKQWNASVRAGKDTLFGREIKENSDLAMIHTGPFYAMEIYPS
HHHHHHHHCCCCCCHHHHHHHHCCHHCCCCHHHCCCHHCCCCCEEEEECCCEEEEEEECH
LANTQGGPRRNERAQIVDPFGDPIPGLYGAGELGSLWGLVYQGGGNIAECLAFGRIAGVS
HHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHEEEEEECCCCHHHHHHHHHHCCCC
AAAGR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11425747; 12368813; 10581551 [H]