| Definition | Geobacter metallireducens GS-15 chromosome, complete genome. |
|---|---|
| Accession | NC_007517 |
| Length | 3,997,420 |
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The map label for this gene is fabG [H]
Identifier: 78222742
GI number: 78222742
Start: 1733278
End: 1734024
Strand: Direct
Name: fabG [H]
Synonym: Gmet_1530
Alternate gene names: 78222742
Gene position: 1733278-1734024 (Clockwise)
Preceding gene: 78222741
Following gene: 78222743
Centisome position: 43.36
GC content: 57.43
Gene sequence:
>747_bases ATGAAAGACAGAACAGCACTGATAGTGGGAGCGGCAAACGATATAGGAGGGGCGATCAGCGTCCGATTCGCGAAACTCGG CGCGCGAGTCGTCCTGATCGATACGGATCGGCAGGAATTGGACAAGGTGTCTGCCCTGGTGGCAGCGGCAGGGGGTGAAG CGGAGGTTATTGCCGTAGACGGTGCAGATTCCGGCGCAGTCAAGAGCACAATAGACGGTATTGCCGGGAAACACGGCTCG ATAGACATCCTGGTCAATGCCATCGACCACAGGGACGGCGTACCGATCACCGAAGGGACCGTCGAGACCTGGGAGCGCTC CCTGAAAGAAAATATCACTCCGCTGGTCTCCTTCTCCCTGAACGTGATCCCGGTGATGAAGAACAACAAGTATGGCCGGA TCGTGAACATCGGCAGCCTCGATTATCTGGGGACAGCGAAGCAGGCCAACTACAGCACCGCAAAATCAGCCATCTTCGGG TTGACACGCTCGTTTGCCCTGGAGCTGGCAAAGGACGGTATTACCGTAAACCAGATCCTGAAGGGGGACGTCAAGACGGC AGAATGTCCCCTCTCCCCTGAAGAGGAGGAGAAAGGGGCTGCCAAGTTGCCGGTGCAGCGTCTGGGCAAGCCGGAGGATA TTGCCTATGCCGCTGCGTATTTTGCCTCCGGCCTGAGCGGCTATGTCACGGGGCAGAACCTTATCGTCTGCGGTGGCAAG AGCATCTATTCGTCAATGTCCGCGTAG
Upstream 100 bases:
>100_bases CCGGCACCGAGCATGCGGCGTGCACCATGCACATGCTGGTAAAGGGGTGGTAAGCGAGGCATCTGACCAATAAATCCTCA ACGGGTAAGGAGAGGCAGTC
Downstream 100 bases:
>100_bases GGGCGGACGTCACATCGGGAGGAAGATCATGGCAGGTTTACAGGGGAAGGTGGCATTGATAACCGGATCGGCAAGCGGTA TGGGGAAGAAGACAGCGCAG
Product: Short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 248; Mature: 248
Protein sequence:
>248_residues MKDRTALIVGAANDIGGAISVRFAKLGARVVLIDTDRQELDKVSALVAAAGGEAEVIAVDGADSGAVKSTIDGIAGKHGS IDILVNAIDHRDGVPITEGTVETWERSLKENITPLVSFSLNVIPVMKNNKYGRIVNIGSLDYLGTAKQANYSTAKSAIFG LTRSFALELAKDGITVNQILKGDVKTAECPLSPEEEEKGAAKLPVQRLGKPEDIAYAAAYFASGLSGYVTGQNLIVCGGK SIYSSMSA
Sequences:
>Translated_248_residues MKDRTALIVGAANDIGGAISVRFAKLGARVVLIDTDRQELDKVSALVAAAGGEAEVIAVDGADSGAVKSTIDGIAGKHGS IDILVNAIDHRDGVPITEGTVETWERSLKENITPLVSFSLNVIPVMKNNKYGRIVNIGSLDYLGTAKQANYSTAKSAIFG LTRSFALELAKDGITVNQILKGDVKTAECPLSPEEEEKGAAKLPVQRLGKPEDIAYAAAYFASGLSGYVTGQNLIVCGGK SIYSSMSA >Mature_248_residues MKDRTALIVGAANDIGGAISVRFAKLGARVVLIDTDRQELDKVSALVAAAGGEAEVIAVDGADSGAVKSTIDGIAGKHGS IDILVNAIDHRDGVPITEGTVETWERSLKENITPLVSFSLNVIPVMKNNKYGRIVNIGSLDYLGTAKQANYSTAKSAIFG LTRSFALELAKDGITVNQILKGDVKTAECPLSPEEEEKGAAKLPVQRLGKPEDIAYAAAYFASGLSGYVTGQNLIVCGGK SIYSSMSA
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=28.9795918367347, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=28.4584980237154, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI5031737, Length=244, Percent_Identity=28.6885245901639, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=28.4, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI40254992, Length=239, Percent_Identity=28.8702928870293, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI66933014, Length=229, Percent_Identity=28.3842794759825, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=25.8687258687259, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=27.1255060728745, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI59889578, Length=236, Percent_Identity=27.1186440677966, Blast_Score=67, Evalue=2e-11, Organism=Escherichia coli, GI1787335, Length=239, Percent_Identity=32.6359832635983, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=31.3953488372093, Blast_Score=104, Evalue=5e-24, Organism=Escherichia coli, GI87082160, Length=244, Percent_Identity=29.0983606557377, Blast_Score=93, Evalue=1e-20, Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=30.4526748971193, Blast_Score=89, Evalue=2e-19, Organism=Escherichia coli, GI1790717, Length=240, Percent_Identity=28.3333333333333, Blast_Score=85, Evalue=5e-18, Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=26.1044176706827, Blast_Score=85, Evalue=6e-18, Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=24.5901639344262, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=25.0965250965251, Blast_Score=75, Evalue=6e-15, Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=26.5060240963855, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=30.5220883534137, Blast_Score=71, Evalue=8e-14, Organism=Escherichia coli, GI2367365, Length=232, Percent_Identity=31.4655172413793, Blast_Score=70, Evalue=9e-14, Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=34.1463414634146, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=31.4176245210728, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=30.4832713754647, Blast_Score=89, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17538480, Length=261, Percent_Identity=32.5670498084291, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17555706, Length=244, Percent_Identity=28.2786885245902, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=29.1666666666667, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17562904, Length=268, Percent_Identity=28.7313432835821, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=28.5140562248996, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=28, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17551412, Length=261, Percent_Identity=30.2681992337165, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=29.1187739463602, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=29.8039215686275, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=28.4, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=27.8195488721804, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17565030, Length=263, Percent_Identity=27.7566539923954, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17563726, Length=268, Percent_Identity=27.2388059701493, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17538486, Length=268, Percent_Identity=29.4776119402985, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17562906, Length=268, Percent_Identity=27.9850746268657, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=28.8389513108614, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17531453, Length=271, Percent_Identity=28.0442804428044, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI193203117, Length=190, Percent_Identity=30.5263157894737, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17508651, Length=247, Percent_Identity=27.5303643724696, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=26.4925373134328, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI193203115, Length=193, Percent_Identity=30.0518134715026, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI72000259, Length=271, Percent_Identity=27.6752767527675, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17562910, Length=269, Percent_Identity=26.0223048327138, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17568967, Length=189, Percent_Identity=32.8042328042328, Blast_Score=69, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6322861, Length=189, Percent_Identity=30.1587301587302, Blast_Score=62, Evalue=7e-11, Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=29.3172690763052, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=29.3172690763052, Blast_Score=88, Evalue=6e-18, Organism=Drosophila melanogaster, GI21355319, Length=241, Percent_Identity=26.1410788381743, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=28.7449392712551, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24644339, Length=246, Percent_Identity=27.6422764227642, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=25.7028112449799, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 25914; Mature: 25914
Theoretical pI: Translated: 5.40; Mature: 5.40
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.2 %Met (Translated Protein) 2.0 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKDRTALIVGAANDIGGAISVRFAKLGARVVLIDTDRQELDKVSALVAAAGGEAEVIAVD CCCCEEEEEECCCCCCCEEEEEEEECCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEEE GADSGAVKSTIDGIAGKHGSIDILVNAIDHRDGVPITEGTVETWERSLKENITPLVSFSL CCCCCCHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCEEEEECE NVIPVMKNNKYGRIVNIGSLDYLGTAKQANYSTAKSAIFGLTRSFALELAKDGITVNQIL EEEEEEECCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHH KGDVKTAECPLSPEEEEKGAAKLPVQRLGKPEDIAYAAAYFASGLSGYVTGQNLIVCGGK CCCCCCCCCCCCCCHHHCCCCCCCHHHCCCCHHHHHHHHHHHCCCCEEEECCEEEEECCH SIYSSMSA HHHHHCCC >Mature Secondary Structure MKDRTALIVGAANDIGGAISVRFAKLGARVVLIDTDRQELDKVSALVAAAGGEAEVIAVD CCCCEEEEEECCCCCCCEEEEEEEECCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEEE GADSGAVKSTIDGIAGKHGSIDILVNAIDHRDGVPITEGTVETWERSLKENITPLVSFSL CCCCCCHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCEEEEECE NVIPVMKNNKYGRIVNIGSLDYLGTAKQANYSTAKSAIFGLTRSFALELAKDGITVNQIL EEEEEEECCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHH KGDVKTAECPLSPEEEEKGAAKLPVQRLGKPEDIAYAAAYFASGLSGYVTGQNLIVCGGK CCCCCCCCCCCCCCHHHCCCCCCCHHHCCCCHHHHHHHHHHHCCCCEEEECCEEEEECCH SIYSSMSA HHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 12089438 [H]