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The map label for this gene is flp [H]

Identifier: 78222719

GI number: 78222719

Start: 1708413

End: 1710200

Strand: Reverse

Name: flp [H]

Synonym: Gmet_1507

Alternate gene names: 78222719

Gene position: 1710200-1708413 (Counterclockwise)

Preceding gene: 78222720

Following gene: 78222696

Centisome position: 42.78

GC content: 59.68

Gene sequence:

>1788_bases
ATGAGAGTGACGCATTTTTTTATGGCCGCGATTGCGGTTGTCTTTGTGCTCGCCGGCTGCTCTACAATGCCGAAGAAGCC
GGACAGTCTGACACGGGGAGATTACGGTTACACGAAGGAGTACGTCTCCTGGCTGATCAAAAAGGAGATGCGGGAAAACG
ACGTGACCGGTCTCAGCATCGCCCTGGTGGACGATCAGCGGGTTGTCTGGGCACAGGGTTTCGGCGTTGCCGATGAGGCG
AACAAGGTGCCGGCCACACCGGATACGATTTACCGGGTCGGCTCCATCTCCAAGCTGTTCACGGCCACCGCGGTCTTGCA
GTTGGCGGAACAGGGCAAAATGGACATCGACAAGCCGCTGTCGACCTACCTGCCCGAATTCTCCGTTAAGAGCCGCTTCC
CCGATGCCGGCCCGATCACTCCCCGCACCCTCATGACCCACCATTCCGGCCTCCCTTCAGACTTCCTGAAAGGGATGTGG
ACGAATAACCCCGAACCTATTTCCAACGTGGTTAATCTGCTGAAGGATGAGTACGCGCAGTATCCCCCCAATTTCGTCTT
CTCCTACTCCAACCTCGGTGTTTCCCTCCTGGGCAATGCGGTGGAGCGAATAGCCGGCCGACCGTATGCCTCCCAGATTG
ATGAGACGGTGCTTCACCCTCTGGGGATGGCCAGTTCGTCATTCTCTACCCATTCCGACGTAGCGTCCCGCCTGGCCAAG
GGATACCGGAACGGGAAGGAGATCGGGGAACCGCAGCTGCGGGACATCCCGGCCGGCGGGCTCCACACCAATGTTCTGGA
TCTTTCCCGCTTCATGGAGATGGTCTTTGCCGGGGGGAAGGCCGGCGAACGGCGGATACTCAAGGAGGAAACGCTTGCGG
AGATGCTCAGCCCGCAGAATGACGGGGTGCCCCTTGACCATGACTTCCACATCGGGCTCGGGTGGCTGCTGACTGACGTC
GGCATCGAAAATGCCGGCAAGGTTGCCTGGCATGACGGCGCCACCCTACTCTACCGCAGCCAGATGGTCATCCTTCCTGA
ACAGAAGCTGGGGGTCGTGGTGCTGTCCAACTCAGCCACGGCTGCTTCCGTGGTGCACAAGGTGGCGACCGAGGCTCTAA
AACTCGCCATGGAGGCCAAGGCAGGCATCCGGCAGCCGGAGCGAAGCAAGCCGGTTGAGCGCGAGGCGGACTTGTCCCCT
GAAGAACGGCAAAAACTGGCGGGCGCCTACGTCACTCCCTTCGGAACTGTCAAAGTAATCGAATCCGGCACTACGCTGCG
GACGGAGTTCTTCGGCAAAACCTTCAGCGTCGTTCCCCGCAATGATGGCCGGATGGGACTCCGGTACAGACTTTTGGGAG
TCATCCCGATAAGTCTGGGAGATCTGGACTATCTCGGGTTCTCCACGTCGACGGTTTCAGGCCATAACGTTCTCCTGGCC
ACGGCAGCGGGGAAGAGCATGCTGGTCGGCGAGAAGATGGAGCCGGTGCTGGTCTCTGAACAATGGCAACGGAGGGTGGG
GGCCTACGAGATCGCTAACCCCGGGGACGACACCATGCTGGTTGACGACATTCGCCTGCGGTACGAAGACGGCTTCCTTC
GGGTCGACTACGCCCTCCCGCTGTTCTTCGACGGGAAGCTCAACGTATCGCTGCAGCCTCTCTCCGACACGGAGGCGGTG
ATCCGTGGCCTGGGTCGGGGGATGGGGGAAACGATCCGTGTAGTTGCGGTCAACGGCGAGGAGATGCTCCAGTATTCAGG
ATATCTGCTCAAAAAGAAGCGAGAGTAA

Upstream 100 bases:

>100_bases
TAACGAACTTTTCCCCATGAGACAGGAAGGCCAGAGGGCGCTGCCCGGTTCAGCCTCGGCGACGAGAGGCTAGTCTTGAC
GTAAAAAGAAGGGAACAATG

Downstream 100 bases:

>100_bases
GCCGTGGATCAGCACGATGATCTGTCTGCCAGGCGTGCTTCCGACGGGGTGCTGGTTCGGCGCTGAACGATAAAGAATCT
GCACCAACCTTCATCAAGGG

Product: Beta-lactamase

Products: NA

Alternate protein names: FmtA-like protein [H]

Number of amino acids: Translated: 595; Mature: 595

Protein sequence:

>595_residues
MRVTHFFMAAIAVVFVLAGCSTMPKKPDSLTRGDYGYTKEYVSWLIKKEMRENDVTGLSIALVDDQRVVWAQGFGVADEA
NKVPATPDTIYRVGSISKLFTATAVLQLAEQGKMDIDKPLSTYLPEFSVKSRFPDAGPITPRTLMTHHSGLPSDFLKGMW
TNNPEPISNVVNLLKDEYAQYPPNFVFSYSNLGVSLLGNAVERIAGRPYASQIDETVLHPLGMASSSFSTHSDVASRLAK
GYRNGKEIGEPQLRDIPAGGLHTNVLDLSRFMEMVFAGGKAGERRILKEETLAEMLSPQNDGVPLDHDFHIGLGWLLTDV
GIENAGKVAWHDGATLLYRSQMVILPEQKLGVVVLSNSATAASVVHKVATEALKLAMEAKAGIRQPERSKPVEREADLSP
EERQKLAGAYVTPFGTVKVIESGTTLRTEFFGKTFSVVPRNDGRMGLRYRLLGVIPISLGDLDYLGFSTSTVSGHNVLLA
TAAGKSMLVGEKMEPVLVSEQWQRRVGAYEIANPGDDTMLVDDIRLRYEDGFLRVDYALPLFFDGKLNVSLQPLSDTEAV
IRGLGRGMGETIRVVAVNGEEMLQYSGYLLKKKRE

Sequences:

>Translated_595_residues
MRVTHFFMAAIAVVFVLAGCSTMPKKPDSLTRGDYGYTKEYVSWLIKKEMRENDVTGLSIALVDDQRVVWAQGFGVADEA
NKVPATPDTIYRVGSISKLFTATAVLQLAEQGKMDIDKPLSTYLPEFSVKSRFPDAGPITPRTLMTHHSGLPSDFLKGMW
TNNPEPISNVVNLLKDEYAQYPPNFVFSYSNLGVSLLGNAVERIAGRPYASQIDETVLHPLGMASSSFSTHSDVASRLAK
GYRNGKEIGEPQLRDIPAGGLHTNVLDLSRFMEMVFAGGKAGERRILKEETLAEMLSPQNDGVPLDHDFHIGLGWLLTDV
GIENAGKVAWHDGATLLYRSQMVILPEQKLGVVVLSNSATAASVVHKVATEALKLAMEAKAGIRQPERSKPVEREADLSP
EERQKLAGAYVTPFGTVKVIESGTTLRTEFFGKTFSVVPRNDGRMGLRYRLLGVIPISLGDLDYLGFSTSTVSGHNVLLA
TAAGKSMLVGEKMEPVLVSEQWQRRVGAYEIANPGDDTMLVDDIRLRYEDGFLRVDYALPLFFDGKLNVSLQPLSDTEAV
IRGLGRGMGETIRVVAVNGEEMLQYSGYLLKKKRE
>Mature_595_residues
MRVTHFFMAAIAVVFVLAGCSTMPKKPDSLTRGDYGYTKEYVSWLIKKEMRENDVTGLSIALVDDQRVVWAQGFGVADEA
NKVPATPDTIYRVGSISKLFTATAVLQLAEQGKMDIDKPLSTYLPEFSVKSRFPDAGPITPRTLMTHHSGLPSDFLKGMW
TNNPEPISNVVNLLKDEYAQYPPNFVFSYSNLGVSLLGNAVERIAGRPYASQIDETVLHPLGMASSSFSTHSDVASRLAK
GYRNGKEIGEPQLRDIPAGGLHTNVLDLSRFMEMVFAGGKAGERRILKEETLAEMLSPQNDGVPLDHDFHIGLGWLLTDV
GIENAGKVAWHDGATLLYRSQMVILPEQKLGVVVLSNSATAASVVHKVATEALKLAMEAKAGIRQPERSKPVEREADLSP
EERQKLAGAYVTPFGTVKVIESGTTLRTEFFGKTFSVVPRNDGRMGLRYRLLGVIPISLGDLDYLGFSTSTVSGHNVLLA
TAAGKSMLVGEKMEPVLVSEQWQRRVGAYEIANPGDDTMLVDDIRLRYEDGFLRVDYALPLFFDGKLNVSLQPLSDTEAV
IRGLGRGMGETIRVVAVNGEEMLQYSGYLLKKKRE

Specific function: Its precise function is unknown. Has no penicillin- binding activity and is not involved in methicillin resistance [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI239747261, Length=290, Percent_Identity=27.2413793103448, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI239752721, Length=290, Percent_Identity=27.2413793103448, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI239741085, Length=290, Percent_Identity=27.2413793103448, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI26051231, Length=95, Percent_Identity=40, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI26051233, Length=95, Percent_Identity=40, Blast_Score=82, Evalue=2e-15,
Organism=Escherichia coli, GI1786574, Length=315, Percent_Identity=25.0793650793651, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1790593, Length=385, Percent_Identity=22.3376623376623, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87082101, Length=412, Percent_Identity=22.5728155339806, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI115533026, Length=350, Percent_Identity=28.8571428571429, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17550934, Length=346, Percent_Identity=28.9017341040462, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 65309; Mature: 65309

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVTHFFMAAIAVVFVLAGCSTMPKKPDSLTRGDYGYTKEYVSWLIKKEMRENDVTGLSI
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEE
ALVDDQRVVWAQGFGVADEANKVPATPDTIYRVGSISKLFTATAVLQLAEQGKMDIDKPL
EEECCCEEEEECCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCH
STYLPEFSVKSRFPDAGPITPRTLMTHHSGLPSDFLKGMWTNNPEPISNVVNLLKDEYAQ
HHHCCCCCHHCCCCCCCCCCCHHHHHHCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHH
YPPNFVFSYSNLGVSLLGNAVERIAGRPYASQIDETVLHPLGMASSSFSTHSDVASRLAK
CCCCEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
GYRNGKEIGEPQLRDIPAGGLHTNVLDLSRFMEMVFAGGKAGERRILKEETLAEMLSPQN
HHCCCHHCCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
DGVPLDHDFHIGLGWLLTDVGIENAGKVAWHDGATLLYRSQMVILPEQKLGVVVLSNSAT
CCCCCCCCCCCCHHHHHHHCCCCCCCCEEEECCCEEEEECEEEEECCCCCCEEEEECCCH
AASVVHKVATEALKLAMEAKAGIRQPERSKPVEREADLSPEERQKLAGAYVTPFGTVKVI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCEECCCCEEEEE
ESGTTLRTEFFGKTFSVVPRNDGRMGLRYRLLGVIPISLGDLDYLGFSTSTVSGHNVLLA
ECCCEEEHHHCCCEEEEEECCCCCCCEEEEEEEEEEECCCCEEECCCCCCCCCCCEEEEE
TAAGKSMLVGEKMEPVLVSEQWQRRVGAYEIANPGDDTMLVDDIRLRYEDGFLRVDYALP
ECCCCEEEECCCCCCEEECHHHHHCCCCEEECCCCCCCEEEEEEEEEEECCEEEEEEECE
LFFDGKLNVSLQPLSDTEAVIRGLGRGMGETIRVVAVNGEEMLQYSGYLLKKKRE
EEECCEEEEEEECCCHHHHHHHHHCCCCCCEEEEEEECHHHHHHHCCHHEECCCC
>Mature Secondary Structure
MRVTHFFMAAIAVVFVLAGCSTMPKKPDSLTRGDYGYTKEYVSWLIKKEMRENDVTGLSI
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEE
ALVDDQRVVWAQGFGVADEANKVPATPDTIYRVGSISKLFTATAVLQLAEQGKMDIDKPL
EEECCCEEEEECCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCH
STYLPEFSVKSRFPDAGPITPRTLMTHHSGLPSDFLKGMWTNNPEPISNVVNLLKDEYAQ
HHHCCCCCHHCCCCCCCCCCCHHHHHHCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHH
YPPNFVFSYSNLGVSLLGNAVERIAGRPYASQIDETVLHPLGMASSSFSTHSDVASRLAK
CCCCEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
GYRNGKEIGEPQLRDIPAGGLHTNVLDLSRFMEMVFAGGKAGERRILKEETLAEMLSPQN
HHCCCHHCCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
DGVPLDHDFHIGLGWLLTDVGIENAGKVAWHDGATLLYRSQMVILPEQKLGVVVLSNSAT
CCCCCCCCCCCCHHHHHHHCCCCCCCCEEEECCCEEEEECEEEEECCCCCCEEEEECCCH
AASVVHKVATEALKLAMEAKAGIRQPERSKPVEREADLSPEERQKLAGAYVTPFGTVKVI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCEECCCCEEEEE
ESGTTLRTEFFGKTFSVVPRNDGRMGLRYRLLGVIPISLGDLDYLGFSTSTVSGHNVLLA
ECCCEEEHHHCCCEEEEEECCCCCCCEEEEEEEEEEECCCCEEECCCCCCCCCCCEEEEE
TAAGKSMLVGEKMEPVLVSEQWQRRVGAYEIANPGDDTMLVDDIRLRYEDGFLRVDYALP
ECCCCEEEECCCCCCEEECHHHHHCCCCEEECCCCCCCEEEEEEEEEEECCEEEEEEECE
LFFDGKLNVSLQPLSDTEAVIRGLGRGMGETIRVVAVNGEEMLQYSGYLLKKKRE
EEECCEEEEEEECCCHHHHHHHHHCCCCCCEEEEEEECHHHHHHHCCHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA