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The map label for this gene is yciR [C]

Identifier: 78222177

GI number: 78222177

Start: 1065296

End: 1067197

Strand: Direct

Name: yciR [C]

Synonym: Gmet_0957

Alternate gene names: 78222177

Gene position: 1065296-1067197 (Clockwise)

Preceding gene: 78222176

Following gene: 78222179

Centisome position: 26.65

GC content: 62.2

Gene sequence:

>1902_bases
ATGGCAGATCTCAAGCGCTACAATGACGGCCTCGTCAAGCTCGACCTCTGGATCAGGAGACTCCTGACCATGGGGGCCCC
TGATCTCATCGACACCGCCCTCTGCGACGGGGCGTGCGACATCGTCCGTGCCGAAACCGGTGTCCTGACGGCCATCAATC
GCCAGGCCGGTCTCCTTACCTTTACGGCGGCTTCCGGGGCCTGGAACCAGATGATGAAAGGGGTCACGGTTCCCCTGCGC
AACGGCAACATCTGCGCGGCTCTGGCCGCCTGCGGAACCCCCCTCAGGGTCGACCGCCTTTCGCTCTTTTGCCGGGAAAG
CTGCGAGCTCTTCCAGGTGGTGGAGATGAATACGGCCCTGCTGGTGCCCATCTTCGACGAGGGAAGGGTGGCTGCCTGTA
TCGCCGCGTTCCGCATGGACAAACCCTTCGACCAGGTCGACGAGCAACTGCTCCAGCAGTATGCCCACTCTGCCTCGGCG
GTGCTGCGCAATTTCCGCCTCATGGAAGATCTCAGGCGCCACGCCGCCATGCTGGAAGAGGAGGTGGCGGAGCGTTCCCG
GGCCGAGGAGCGGATTCGCCAGATGGCCTATTACGATTCCCTCACCGGGCTTCCCAACCGGCGACTCTTCAATGACCGTC
TCCGGCAGTCCCTCGCCCTGGCCCAGCGCCACAAGAGGCCCTTGGCGGTCATGTTCCTGGACCTGGACCGCTTCAAGCTC
ATCAATGATACCCTCGGCCACGCCGTGGGAGACAGGCTCCTTATGGCGGTGGCAAAGCGCCTTAGAAACTGCTGTCGCCG
CGAGGGGGACACGGTGGCGCGCCAGGGAGGCGACGAGTTCATCATCAACCTATCGGCCATCTCGGATGTGAAGGACGCCT
TCACGGTGGCCCAGAAGATCATCGACGTCTTCAGAACACCCTTCGTCATTGACGGATATGAGTTGTTCATCACCACGAGC
ATCGGGATCAGCGTCTATCCCCACGACGGACGCTCCGGCGATGCCCTGGTGAAAAACGCCGACGTTGCCATGTACCGCGC
CAAAGAGCAGGGACGCAACAACTGTCAGCTGTTTGCCCCTGAGATGAATGCCCGGGCCTTTGAGCGGCTCTCTCTGGAGA
ACGACATGCGGCGGGCGCTGGAGCGGGACGAATTCGTCCTCCACTATCAGCCCAAGGTGAACGTGGAGCATGGCCAGATC
GCCTGCATGGAGGCCCTGGTCCGCTGGCAGCATCCCAGCATGGGGCTTGTTCCTCCGTCCCGCTTCATTCCCCTGGCCGA
GGAGACCGGGCTCATCGTTCCCTTGGGAGAGTGGGTCTTGCGAACCGCCTGCCAGCAGAACCGGGCATGGCAGGATGCCG
GCTATCCCACCATGCAGGTGGCGGTAAATCTCTCACCCCGCCAGCTCCGGCAGGGAGACCTGTCGGAGACGGTGGCGCGG
GTCCTGGCGGAGACCGGGCTTGCCCCGGGGTGGCTCGTCATCGAGGTTACCGAAAGCATCCTCATGGACGATGCCGAGGA
GACGATCAGAACCTTCCGGCGGCTGGATAGAATGGGGGTCCGGATTTCCATCGACGATTTCGGCACTGGTTATTCGTCGC
TTCACTATCTGAAAAAGTTTCCGGTCCATACCCTCAAGATCGACCGTTCCTTCGTACGTGAGATCGCCTCCAACCCGGAC
GATGAGGCCATTGCCGGCGCTGTCATCAGCATGGCAAAAGGGCTCAACCTGGGAGTGGTTGCGGAGGGGGTGGAAACCGT
GGAGCAGATGGAAGTGCTCAGGGCACTGAACTGCCGGTACATGCAGGGATTCCTCTTCAGCGAGCCCGCTCCCGCCGAGC
AGTTCACCCCGGTGCTCGGTCACGCGGCCACGCCGTATCTCAACTTCGGCAAGTGGTGTTGA

Upstream 100 bases:

>100_bases
GGGTGGAAGGTGTTTTGCATTTCGTTTTCTGACCCTCTTGTTGTCAAATTTGTGACTGTTGGGGGATCTTACGGAAGTGA
AGGCCCGGCGTACGTAATTT

Downstream 100 bases:

>100_bases
GCGGGAAAAGCATCTGAAACACGGAGCAACCGTGTTCTCAGTCAACAAATTAGTGCAGAAGTGGAGTGAATTTCGAGTGA
TCCCACTTCTGGTTGTTTTT

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 633; Mature: 632

Protein sequence:

>633_residues
MADLKRYNDGLVKLDLWIRRLLTMGAPDLIDTALCDGACDIVRAETGVLTAINRQAGLLTFTAASGAWNQMMKGVTVPLR
NGNICAALAACGTPLRVDRLSLFCRESCELFQVVEMNTALLVPIFDEGRVAACIAAFRMDKPFDQVDEQLLQQYAHSASA
VLRNFRLMEDLRRHAAMLEEEVAERSRAEERIRQMAYYDSLTGLPNRRLFNDRLRQSLALAQRHKRPLAVMFLDLDRFKL
INDTLGHAVGDRLLMAVAKRLRNCCRREGDTVARQGGDEFIINLSAISDVKDAFTVAQKIIDVFRTPFVIDGYELFITTS
IGISVYPHDGRSGDALVKNADVAMYRAKEQGRNNCQLFAPEMNARAFERLSLENDMRRALERDEFVLHYQPKVNVEHGQI
ACMEALVRWQHPSMGLVPPSRFIPLAEETGLIVPLGEWVLRTACQQNRAWQDAGYPTMQVAVNLSPRQLRQGDLSETVAR
VLAETGLAPGWLVIEVTESILMDDAEETIRTFRRLDRMGVRISIDDFGTGYSSLHYLKKFPVHTLKIDRSFVREIASNPD
DEAIAGAVISMAKGLNLGVVAEGVETVEQMEVLRALNCRYMQGFLFSEPAPAEQFTPVLGHAATPYLNFGKWC

Sequences:

>Translated_633_residues
MADLKRYNDGLVKLDLWIRRLLTMGAPDLIDTALCDGACDIVRAETGVLTAINRQAGLLTFTAASGAWNQMMKGVTVPLR
NGNICAALAACGTPLRVDRLSLFCRESCELFQVVEMNTALLVPIFDEGRVAACIAAFRMDKPFDQVDEQLLQQYAHSASA
VLRNFRLMEDLRRHAAMLEEEVAERSRAEERIRQMAYYDSLTGLPNRRLFNDRLRQSLALAQRHKRPLAVMFLDLDRFKL
INDTLGHAVGDRLLMAVAKRLRNCCRREGDTVARQGGDEFIINLSAISDVKDAFTVAQKIIDVFRTPFVIDGYELFITTS
IGISVYPHDGRSGDALVKNADVAMYRAKEQGRNNCQLFAPEMNARAFERLSLENDMRRALERDEFVLHYQPKVNVEHGQI
ACMEALVRWQHPSMGLVPPSRFIPLAEETGLIVPLGEWVLRTACQQNRAWQDAGYPTMQVAVNLSPRQLRQGDLSETVAR
VLAETGLAPGWLVIEVTESILMDDAEETIRTFRRLDRMGVRISIDDFGTGYSSLHYLKKFPVHTLKIDRSFVREIASNPD
DEAIAGAVISMAKGLNLGVVAEGVETVEQMEVLRALNCRYMQGFLFSEPAPAEQFTPVLGHAATPYLNFGKWC
>Mature_632_residues
ADLKRYNDGLVKLDLWIRRLLTMGAPDLIDTALCDGACDIVRAETGVLTAINRQAGLLTFTAASGAWNQMMKGVTVPLRN
GNICAALAACGTPLRVDRLSLFCRESCELFQVVEMNTALLVPIFDEGRVAACIAAFRMDKPFDQVDEQLLQQYAHSASAV
LRNFRLMEDLRRHAAMLEEEVAERSRAEERIRQMAYYDSLTGLPNRRLFNDRLRQSLALAQRHKRPLAVMFLDLDRFKLI
NDTLGHAVGDRLLMAVAKRLRNCCRREGDTVARQGGDEFIINLSAISDVKDAFTVAQKIIDVFRTPFVIDGYELFITTSI
GISVYPHDGRSGDALVKNADVAMYRAKEQGRNNCQLFAPEMNARAFERLSLENDMRRALERDEFVLHYQPKVNVEHGQIA
CMEALVRWQHPSMGLVPPSRFIPLAEETGLIVPLGEWVLRTACQQNRAWQDAGYPTMQVAVNLSPRQLRQGDLSETVARV
LAETGLAPGWLVIEVTESILMDDAEETIRTFRRLDRMGVRISIDDFGTGYSSLHYLKKFPVHTLKIDRSFVREIASNPDD
EAIAGAVISMAKGLNLGVVAEGVETVEQMEVLRALNCRYMQGFLFSEPAPAEQFTPVLGHAATPYLNFGKWC

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=435, Percent_Identity=40.6896551724138, Blast_Score=342, Evalue=4e-95,
Organism=Escherichia coli, GI87081921, Length=447, Percent_Identity=36.6890380313199, Blast_Score=278, Evalue=6e-76,
Organism=Escherichia coli, GI226510982, Length=441, Percent_Identity=30.6122448979592, Blast_Score=209, Evalue=5e-55,
Organism=Escherichia coli, GI1788502, Length=251, Percent_Identity=33.4661354581673, Blast_Score=156, Evalue=4e-39,
Organism=Escherichia coli, GI87081980, Length=257, Percent_Identity=33.4630350194552, Blast_Score=146, Evalue=4e-36,
Organism=Escherichia coli, GI87081845, Length=238, Percent_Identity=34.0336134453782, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI1790496, Length=253, Percent_Identity=33.9920948616601, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1786507, Length=254, Percent_Identity=30.3149606299213, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI87081743, Length=245, Percent_Identity=34.2857142857143, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI1788849, Length=445, Percent_Identity=28.314606741573, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1787055, Length=246, Percent_Identity=32.520325203252, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI87082096, Length=252, Percent_Identity=31.7460317460317, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI87081881, Length=179, Percent_Identity=39.6648044692737, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1788381, Length=437, Percent_Identity=24.9427917620137, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI87081977, Length=252, Percent_Identity=29.7619047619048, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1786584, Length=179, Percent_Identity=31.2849162011173, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI145693134, Length=181, Percent_Identity=35.3591160220994, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787816, Length=169, Percent_Identity=37.2781065088757, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1788956, Length=158, Percent_Identity=36.0759493670886, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787802, Length=186, Percent_Identity=31.1827956989247, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787262, Length=164, Percent_Identity=36.5853658536585, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87082007, Length=176, Percent_Identity=32.9545454545455, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1789650, Length=432, Percent_Identity=21.7592592592593, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787410, Length=150, Percent_Identity=26.6666666666667, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 71005; Mature: 70874

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLKRYNDGLVKLDLWIRRLLTMGAPDLIDTALCDGACDIVRAETGVLTAINRQAGLLT
CCCCHHHCCCEEEHHHHHHHHHHCCCCHHHHHHHHCCCHHHHCCCCCCEEEECCCCCEEE
FTAASGAWNQMMKGVTVPLRNGNICAALAACGTPLRVDRLSLFCRESCELFQVVEMNTAL
EEECCCHHHHHHCCCEEEECCCCEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
LVPIFDEGRVAACIAAFRMDKPFDQVDEQLLQQYAHSASAVLRNFRLMEDLRRHAAMLEE
EEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVAERSRAEERIRQMAYYDSLTGLPNRRLFNDRLRQSLALAQRHKRPLAVMFLDLDRFKL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHH
INDTLGHAVGDRLLMAVAKRLRNCCRREGDTVARQGGDEFIINLSAISDVKDAFTVAQKI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEEEHHHHHHHHHHHHHHHH
IDVFRTPFVIDGYELFITTSIGISVYPHDGRSGDALVKNADVAMYRAKEQGRNNCQLFAP
HHHHCCCEEECCEEEEEEEECCEEEECCCCCCCCCEEECCCHHHHCCHHCCCCCCEEECC
EMNARAFERLSLENDMRRALERDEFVLHYQPKVNVEHGQIACMEALVRWQHPSMGLVPPS
CCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCH
RFIPLAEETGLIVPLGEWVLRTACQQNRAWQDAGYPTMQVAVNLSPRQLRQGDLSETVAR
HCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCHHHHHCCCHHHHHHH
VLAETGLAPGWLVIEVTESILMDDAEETIRTFRRLDRMGVRISIDDFGTGYSSLHYLKKF
HHHHHCCCCCEEEEEEHHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHC
PVHTLKIDRSFVREIASNPDDEAIAGAVISMAKGLNLGVVAEGVETVEQMEVLRALNCRY
CCCEEECCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
MQGFLFSEPAPAEQFTPVLGHAATPYLNFGKWC
HHCCCCCCCCCHHHHCHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
ADLKRYNDGLVKLDLWIRRLLTMGAPDLIDTALCDGACDIVRAETGVLTAINRQAGLLT
CCCHHHCCCEEEHHHHHHHHHHCCCCHHHHHHHHCCCHHHHCCCCCCEEEECCCCCEEE
FTAASGAWNQMMKGVTVPLRNGNICAALAACGTPLRVDRLSLFCRESCELFQVVEMNTAL
EEECCCHHHHHHCCCEEEECCCCEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
LVPIFDEGRVAACIAAFRMDKPFDQVDEQLLQQYAHSASAVLRNFRLMEDLRRHAAMLEE
EEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVAERSRAEERIRQMAYYDSLTGLPNRRLFNDRLRQSLALAQRHKRPLAVMFLDLDRFKL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHH
INDTLGHAVGDRLLMAVAKRLRNCCRREGDTVARQGGDEFIINLSAISDVKDAFTVAQKI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEEEHHHHHHHHHHHHHHHH
IDVFRTPFVIDGYELFITTSIGISVYPHDGRSGDALVKNADVAMYRAKEQGRNNCQLFAP
HHHHCCCEEECCEEEEEEEECCEEEECCCCCCCCCEEECCCHHHHCCHHCCCCCCEEECC
EMNARAFERLSLENDMRRALERDEFVLHYQPKVNVEHGQIACMEALVRWQHPSMGLVPPS
CCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCH
RFIPLAEETGLIVPLGEWVLRTACQQNRAWQDAGYPTMQVAVNLSPRQLRQGDLSETVAR
HCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCHHHHHCCCHHHHHHH
VLAETGLAPGWLVIEVTESILMDDAEETIRTFRRLDRMGVRISIDDFGTGYSSLHYLKKF
HHHHHCCCCCEEEEEEHHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHC
PVHTLKIDRSFVREIASNPDDEAIAGAVISMAKGLNLGVVAEGVETVEQMEVLRALNCRY
CCCEEECCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
MQGFLFSEPAPAEQFTPVLGHAATPYLNFGKWC
HHCCCCCCCCCHHHHCHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]