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The map label for this gene is mreC [H]

Identifier: 78222146

GI number: 78222146

Start: 1020264

End: 1021085

Strand: Direct

Name: mreC [H]

Synonym: Gmet_0926

Alternate gene names: 78222146

Gene position: 1020264-1021085 (Clockwise)

Preceding gene: 78222145

Following gene: 78222147

Centisome position: 25.52

GC content: 62.41

Gene sequence:

>822_bases
ATGCTCGAACTGATCAGGAAATACCGGTTCCACCTGCTGACCGGCGCGGCCCTGCTGGCGGCCCTTGCCTTCTATTCCCT
CAGCCTGCGGGATCGGGAGCACGCAAGCGGCTTTGAACGCATGGTCATCGATCTCTTTGCGCCGGTTCACAACGTTGGTG
CCGGTGTCAGCGGTTTTTTTTCCGGCGTCTGGAATGACTACATCGACCTGGTTGACGTCCGGGCAGAGAACAAGCAGCTG
CGCGAGTCGGTGAAGACCCTCAACTCCCGCCTGATCGAGAACCGGGAGGCAATCCACGAGAACATGCGGTTGAGGCAGCT
CCTGGACCTGAAGGCGATCCAGCGGGCGCCGTCGGTGGCCGCCATGGTGATCGGTGAAGACAGCTCCCCCTGGTTCAAGA
CCCTGGTCATCAACCGGGGGGCGGTGGACGGCCTCCAGGAAGGGATGCCGGTGGTGGCCGCCAACGGCGTGGTGGGCCAG
GTGATCAAGGTGGCGGCGGGGAGTTCCCGCGTGTTGCTCCTCACCGACACCGCCAGCGGCATAGCCTCGGTGGTCCAGCG
TTCCCGGGCCAGGGGTGTTGTCAAGGGGAAGGGGGGCGGTCTCTGTTTCCTCGAATTCTCCCTCCGGGAGGAAGATGTGA
AGGTCGGCGACATGGTTGTGACCTCCGGCATCGGGGGGATCTTCCCCAAGGGGCTCGTCATCGGCGAAGTGACCATGGTG
AGGAAGGGAGAATACGGCATCTTCCAGACCATCAGCGTTCGTCCGGCCGTGAATATGGCAAGGCTTGAGGAAGTTCTCGT
TCTCTTGCAGAAGGCGCCATGA

Upstream 100 bases:

>100_bases
ACGTCACAGCCGTTGCCCTTGATCGGCGATATGCCGATCTACCCTCGAATCTTTCGGCCGAACGGACCGTTTGCGGTTCC
CGAGGCCAGAACATCGCTCC

Downstream 100 bases:

>100_bases
TCAAGTTCCTCTGGTACGCCATCCTTGTCTTCGCGGCGCTCGTCATGCAGGTAACCCTCTTTCCTGCGCATATTGCCGAT
CCCTTCAAGCCCAACCTCCT

Product: rod shape-determining protein MreC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MLELIRKYRFHLLTGAALLAALAFYSLSLRDREHASGFERMVIDLFAPVHNVGAGVSGFFSGVWNDYIDLVDVRAENKQL
RESVKTLNSRLIENREAIHENMRLRQLLDLKAIQRAPSVAAMVIGEDSSPWFKTLVINRGAVDGLQEGMPVVAANGVVGQ
VIKVAAGSSRVLLLTDTASGIASVVQRSRARGVVKGKGGGLCFLEFSLREEDVKVGDMVVTSGIGGIFPKGLVIGEVTMV
RKGEYGIFQTISVRPAVNMARLEEVLVLLQKAP

Sequences:

>Translated_273_residues
MLELIRKYRFHLLTGAALLAALAFYSLSLRDREHASGFERMVIDLFAPVHNVGAGVSGFFSGVWNDYIDLVDVRAENKQL
RESVKTLNSRLIENREAIHENMRLRQLLDLKAIQRAPSVAAMVIGEDSSPWFKTLVINRGAVDGLQEGMPVVAANGVVGQ
VIKVAAGSSRVLLLTDTASGIASVVQRSRARGVVKGKGGGLCFLEFSLREEDVKVGDMVVTSGIGGIFPKGLVIGEVTMV
RKGEYGIFQTISVRPAVNMARLEEVLVLLQKAP
>Mature_273_residues
MLELIRKYRFHLLTGAALLAALAFYSLSLRDREHASGFERMVIDLFAPVHNVGAGVSGFFSGVWNDYIDLVDVRAENKQL
RESVKTLNSRLIENREAIHENMRLRQLLDLKAIQRAPSVAAMVIGEDSSPWFKTLVINRGAVDGLQEGMPVVAANGVVGQ
VIKVAAGSSRVLLLTDTASGIASVVQRSRARGVVKGKGGGLCFLEFSLREEDVKVGDMVVTSGIGGIFPKGLVIGEVTMV
RKGEYGIFQTISVRPAVNMARLEEVLVLLQKAP

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG1792

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Inner Membrane-Anchored [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreC family [H]

Homologues:

Organism=Escherichia coli, GI1789648, Length=214, Percent_Identity=32.7102803738318, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007221
- InterPro:   IPR005223 [H]

Pfam domain/function: PF04085 MreC [H]

EC number: NA

Molecular weight: Translated: 29644; Mature: 29644

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLELIRKYRFHLLTGAALLAALAFYSLSLRDREHASGFERMVIDLFAPVHNVGAGVSGFF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
SGVWNDYIDLVDVRAENKQLRESVKTLNSRLIENREAIHENMRLRQLLDLKAIQRAPSVA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
AMVIGEDSSPWFKTLVINRGAVDGLQEGMPVVAANGVVGQVIKVAAGSSRVLLLTDTASG
EEEEECCCCCHHHHEEECCCCHHHHHCCCCEEEECCHHHHHHHHHCCCCEEEEEECCHHH
IASVVQRSRARGVVKGKGGGLCFLEFSLREEDVKVGDMVVTSGIGGIFPKGLVIGEVTMV
HHHHHHHHHHCCCEEECCCCEEEEEEECCCCCCCHHHEEEECCCCCCCCCCEEEEEEEEE
RKGEYGIFQTISVRPAVNMARLEEVLVLLQKAP
ECCCCCEEEEEECCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLELIRKYRFHLLTGAALLAALAFYSLSLRDREHASGFERMVIDLFAPVHNVGAGVSGFF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
SGVWNDYIDLVDVRAENKQLRESVKTLNSRLIENREAIHENMRLRQLLDLKAIQRAPSVA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
AMVIGEDSSPWFKTLVINRGAVDGLQEGMPVVAANGVVGQVIKVAAGSSRVLLLTDTASG
EEEEECCCCCHHHHEEECCCCHHHHHCCCCEEEECCHHHHHHHHHCCCCEEEEEECCHHH
IASVVQRSRARGVVKGKGGGLCFLEFSLREEDVKVGDMVVTSGIGGIFPKGLVIGEVTMV
HHHHHHHHHHCCCEEECCCCEEEEEEECCCCCCCHHHEEEECCCCCCCCCCEEEEEEEEE
RKGEYGIFQTISVRPAVNMARLEEVLVLLQKAP
ECCCCCEEEEEECCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1400225; 1400224; 9384377 [H]