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The map label for this gene is ppiD [H]

Identifier: 78222137

GI number: 78222137

Start: 1010934

End: 1012583

Strand: Reverse

Name: ppiD [H]

Synonym: Gmet_0917

Alternate gene names: 78222137

Gene position: 1012583-1010934 (Counterclockwise)

Preceding gene: 78222158

Following gene: 78222136

Centisome position: 25.33

GC content: 60.73

Gene sequence:

>1650_bases
ATGCGAACCCGTTGTTTCAGGGGTTACGGCACCGATTTCCCTCACGCAAAGGAGTCCTCGCGAATGCTCGGCATCATGCG
AAAGTACAAGCAGTCCATCGTCATCAAGGTGGTCTTCGGCCTCATCGTCCTCAGCTTCATCGGCACCATTTTTCTTGTCT
GGGGCAAGGGTGACGGGGGACTCACCCCGTCGAGTTATGCCGTCAAGGTGGATCGCACCAAGGTCAGTTACGAAGAATTC
CAGCGAACCTACTACCGTCTGCGCGACATCTACACCCAGATTTACGGTCCGGCCCTCACTCCCGAGGTGGAGAAGCAGCT
CAACCTGAAGAAACAGGCCCTGGACTCCCTCATCGATGCGGCGCTGTTGCGGAAGGCCGCCAAAGACATGGGGGTAAAGG
TATCCGAAGAAGAGGTGCAGAAGGCCATCGCCGCCATCCCCGCGTTCCAGAAAAACGGCGCCTTTGACTCCGCCCAGTAC
TTCGCCGTCCTCAAGGCGAACCGGCTCGCTCCCAAGGAGTTCGAGGCGGGCCAGAAGGACGAGCTCATGGTGAAAAAGGC
CCAGGACCAGATCAAGGCGAAGGTCCAGGTCACCGATGATGCGGCGCGGCAGCTCTACAAAAAAAGGAACGACCGGCTCA
ATCTCCAGTTCACCTCCTTTTCGCCGGAAGAGCTCAAGGGGGAGATCAAACTCTCCGACCAGGAACTCACCGACTTCCTC
GCCAAGAACCAGAATGAGTTCAAGACTCCAGAGCAGATAAGCGTCTCCTACGTCCTGGCCGACCCGGCCAAGCTAGCAGG
AAAGGTGGAGGTTACCGAGGCCGACATCCAGTCCTGGTACCAGAAGAACATCGACCGCTACCAGGGCAAGGGAGGCATCC
TCCCCCTGGCCGAGGTCAAGGAGCAGGTGAAGGCCGACGCCCAGCGTTTCTATGCGGGTCAGAAGGCCTACGAGCTTGCC
GCTGCCTCCGTGAACAAGCATAAGACCGCAGGGGATCTGGCCGCCGTGGCCCGGGAACTGGGAGTGGCCGTCAGCGAAAC
CCCGCTCTTTACCGCAAAAGCTCCCGCACCGGCCCTGGCCGGCGAGAAAGAAGTGCTCACGCGGGCATTCCTCCTCAAGC
AGAATGAGTTGGGCGGCCCGGTGGAGACCCCCAAGGGGATCTACATCCTGAAGCTCAAGGAGCGCAAACCCTCCGACGTG
CCGCCGCTGGCCCAGATTCGCGCGAAGGTCGAAGAAAGGGCCAAGGCCGTCAGGGCGGTGGAACTCGCCAAGAAGAAGGC
CGAGGAGGCCCAGGCGAAGCTCGCCAAGGGAGACACGGCCGGCCTCAAGCTGCAGGAGACCGGAAGCTTTGCCTTTGACG
CCAAGGGGAACGTTCCGGTGATCGGGACATCGCCCGAACTCATGGAAGCGGCCTTCACGCTGACCGACAAGGCCCCCGCC
CCCCAGGCTCCCGTCAAGATCGGCAACCGCTGGGTCGCCTTCAGGCTCAAGGAGCGCACCGAGCTGAACGCTGCCGCCTT
CCCGGCCGAGAAGGAAAAGATCAAGCAGGAACTCCTCCCGAAAAAGCAGGAGGAAGAGTTGCAGAAGTGGCTCAAGGAGC
TGCGCGCGAAGGCGAAGATCGAGATCAACCCTGCCCTCAAGGATCAGTAG

Upstream 100 bases:

>100_bases
TCGAAGCGTTGCATCGTAGCAGAAACCCCCTGGGCATGCAAGGGGGAAAAGCTTGACCGGGAGTATTCAATGTTGCTTTT
GCAAGGCAGGTTATAGTACT

Downstream 100 bases:

>100_bases
CGGGCACTATCACACGATTTACGAAAAAGGAGACTGAGCCATGGCAAACCTGGTCCTCAAAACCGACTTCCCCGATCTGA
AGCTTGTGGCCCGCGGCAAG

Product: hypothetical protein

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MRTRCFRGYGTDFPHAKESSRMLGIMRKYKQSIVIKVVFGLIVLSFIGTIFLVWGKGDGGLTPSSYAVKVDRTKVSYEEF
QRTYYRLRDIYTQIYGPALTPEVEKQLNLKKQALDSLIDAALLRKAAKDMGVKVSEEEVQKAIAAIPAFQKNGAFDSAQY
FAVLKANRLAPKEFEAGQKDELMVKKAQDQIKAKVQVTDDAARQLYKKRNDRLNLQFTSFSPEELKGEIKLSDQELTDFL
AKNQNEFKTPEQISVSYVLADPAKLAGKVEVTEADIQSWYQKNIDRYQGKGGILPLAEVKEQVKADAQRFYAGQKAYELA
AASVNKHKTAGDLAAVARELGVAVSETPLFTAKAPAPALAGEKEVLTRAFLLKQNELGGPVETPKGIYILKLKERKPSDV
PPLAQIRAKVEERAKAVRAVELAKKKAEEAQAKLAKGDTAGLKLQETGSFAFDAKGNVPVIGTSPELMEAAFTLTDKAPA
PQAPVKIGNRWVAFRLKERTELNAAAFPAEKEKIKQELLPKKQEEELQKWLKELRAKAKIEINPALKDQ

Sequences:

>Translated_549_residues
MRTRCFRGYGTDFPHAKESSRMLGIMRKYKQSIVIKVVFGLIVLSFIGTIFLVWGKGDGGLTPSSYAVKVDRTKVSYEEF
QRTYYRLRDIYTQIYGPALTPEVEKQLNLKKQALDSLIDAALLRKAAKDMGVKVSEEEVQKAIAAIPAFQKNGAFDSAQY
FAVLKANRLAPKEFEAGQKDELMVKKAQDQIKAKVQVTDDAARQLYKKRNDRLNLQFTSFSPEELKGEIKLSDQELTDFL
AKNQNEFKTPEQISVSYVLADPAKLAGKVEVTEADIQSWYQKNIDRYQGKGGILPLAEVKEQVKADAQRFYAGQKAYELA
AASVNKHKTAGDLAAVARELGVAVSETPLFTAKAPAPALAGEKEVLTRAFLLKQNELGGPVETPKGIYILKLKERKPSDV
PPLAQIRAKVEERAKAVRAVELAKKKAEEAQAKLAKGDTAGLKLQETGSFAFDAKGNVPVIGTSPELMEAAFTLTDKAPA
PQAPVKIGNRWVAFRLKERTELNAAAFPAEKEKIKQELLPKKQEEELQKWLKELRAKAKIEINPALKDQ
>Mature_549_residues
MRTRCFRGYGTDFPHAKESSRMLGIMRKYKQSIVIKVVFGLIVLSFIGTIFLVWGKGDGGLTPSSYAVKVDRTKVSYEEF
QRTYYRLRDIYTQIYGPALTPEVEKQLNLKKQALDSLIDAALLRKAAKDMGVKVSEEEVQKAIAAIPAFQKNGAFDSAQY
FAVLKANRLAPKEFEAGQKDELMVKKAQDQIKAKVQVTDDAARQLYKKRNDRLNLQFTSFSPEELKGEIKLSDQELTDFL
AKNQNEFKTPEQISVSYVLADPAKLAGKVEVTEADIQSWYQKNIDRYQGKGGILPLAEVKEQVKADAQRFYAGQKAYELA
AASVNKHKTAGDLAAVARELGVAVSETPLFTAKAPAPALAGEKEVLTRAFLLKQNELGGPVETPKGIYILKLKERKPSDV
PPLAQIRAKVEERAKAVRAVELAKKKAEEAQAKLAKGDTAGLKLQETGSFAFDAKGNVPVIGTSPELMEAAFTLTDKAPA
PQAPVKIGNRWVAFRLKERTELNAAAFPAEKEKIKQELLPKKQEEELQKWLKELRAKAKIEINPALKDQ

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=505, Percent_Identity=25.3465346534653, Blast_Score=131, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 61002; Mature: 61002

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTRCFRGYGTDFPHAKESSRMLGIMRKYKQSIVIKVVFGLIVLSFIGTIFLVWGKGDGG
CCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCC
LTPSSYAVKVDRTKVSYEEFQRTYYRLRDIYTQIYGPALTPEVEKQLNLKKQALDSLIDA
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
ALLRKAAKDMGVKVSEEEVQKAIAAIPAFQKNGAFDSAQYFAVLKANRLAPKEFEAGQKD
HHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCHHHCCCCCH
ELMVKKAQDQIKAKVQVTDDAARQLYKKRNDRLNLQFTSFSPEELKGEIKLSDQELTDFL
HHHHHHHHHHHEEEEEECCHHHHHHHHHCCCEEEEEEECCCHHHCCCCEEECHHHHHHHH
AKNQNEFKTPEQISVSYVLADPAKLAGKVEVTEADIQSWYQKNIDRYQGKGGILPLAEVK
HCCCCCCCCCCCEEEEEEEECHHHHCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
EQVKADAQRFYAGQKAYELAAASVNKHKTAGDLAAVARELGVAVSETPLFTAKAPAPALA
HHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEECCCCCEEECCCCCCCC
GEKEVLTRAFLLKQNELGGPVETPKGIYILKLKERKPSDVPPLAQIRAKVEERAKAVRAV
CCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
ELAKKKAEEAQAKLAKGDTAGLKLQETGSFAFDAKGNVPVIGTSPELMEAAFTLTDKAPA
HHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEECCCCEEEECCCHHHHHHHHHHCCCCCC
PQAPVKIGNRWVAFRLKERTELNAAAFPAEKEKIKQELLPKKQEEELQKWLKELRAKAKI
CCCCHHHCCEEEEEEECCCCCCCHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEE
EINPALKDQ
EECCCCCCC
>Mature Secondary Structure
MRTRCFRGYGTDFPHAKESSRMLGIMRKYKQSIVIKVVFGLIVLSFIGTIFLVWGKGDGG
CCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCC
LTPSSYAVKVDRTKVSYEEFQRTYYRLRDIYTQIYGPALTPEVEKQLNLKKQALDSLIDA
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
ALLRKAAKDMGVKVSEEEVQKAIAAIPAFQKNGAFDSAQYFAVLKANRLAPKEFEAGQKD
HHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCHHHCCCCCH
ELMVKKAQDQIKAKVQVTDDAARQLYKKRNDRLNLQFTSFSPEELKGEIKLSDQELTDFL
HHHHHHHHHHHEEEEEECCHHHHHHHHHCCCEEEEEEECCCHHHCCCCEEECHHHHHHHH
AKNQNEFKTPEQISVSYVLADPAKLAGKVEVTEADIQSWYQKNIDRYQGKGGILPLAEVK
HCCCCCCCCCCCEEEEEEEECHHHHCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
EQVKADAQRFYAGQKAYELAAASVNKHKTAGDLAAVARELGVAVSETPLFTAKAPAPALA
HHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEECCCCCEEECCCCCCCC
GEKEVLTRAFLLKQNELGGPVETPKGIYILKLKERKPSDVPPLAQIRAKVEERAKAVRAV
CCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
ELAKKKAEEAQAKLAKGDTAGLKLQETGSFAFDAKGNVPVIGTSPELMEAAFTLTDKAPA
HHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEECCCCEEEECCCHHHHHHHHHHCCCCCC
PQAPVKIGNRWVAFRLKERTELNAAAFPAEKEKIKQELLPKKQEEELQKWLKELRAKAKI
CCCCHHHCCEEEEEEECCCCCCCHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEE
EINPALKDQ
EECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]