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The map label for this gene is 78222122

Identifier: 78222122

GI number: 78222122

Start: 992180

End: 993373

Strand: Direct

Name: 78222122

Synonym: Gmet_0902

Alternate gene names: NA

Gene position: 992180-993373 (Clockwise)

Preceding gene: 78222121

Following gene: 78222123

Centisome position: 24.82

GC content: 61.39

Gene sequence:

>1194_bases
ATGAGCAAGGTACTGATAATCGGAGCCGGCGGCGTCGGCCAGGTCGTTGCACACAAATGCGCCCAGCGCCGGGACATCTT
CAGCGAGATCACCCTGGCCTCTCGGACCAAGTCCAAGTGTGACGCCATCGCTGCCCAGCTGAATAACACCATTGCCACGG
CCCAGGTGAATGCCGACAACGTCCCCGAACTGGTGGCGCTCATCAGGAAGGAGCAACCGAAGCTCGTCATCAACGTGGCC
CTGCCGTACCAGGATCTGACCATCATGGACGCCTGCCTGGAAACCGGCGTGGACTATCTCGACACCGCCAACTACGAGCC
CCTGGACACCGCCAAGTTCGAGTACTCCTGGCAGTGGGCCTACCAGGAGCGCTTCAAGGCTGCGGGGCTCATGGCGTTGC
TGGGTTCCGGCTTCGATCCGGGCGTCACCAACGTCTATACGGCACTAGCCGCCAAGAAGTACCTGGATGAGGTGGAGGAG
CTCGACATCATCGACGCCAACGCCGGCAGCCACGGCCAGCCCTTCGCCACCAACTTCAACCCGGAGATCAATATCCGTGA
AGTGACCGCCGTCTGCCGCCACTGGGAGAACGGCCAGTTCGTGGAGTCGCCGCCCCTCTCCACCAAGCGGGTCTTCGACT
TCCCCGAGGGCATCGGCCCTATGAACATCTACCGCCTTTACCACGAGGAGATGGAGTCCATCGTCAAGCATATCCCGACC
ATCAAGAAGGCCCAGTTCTGGATGACCTTCTCCGACAACTACCTGAAGCACCTGGAAGTGCTCCAGAACGTGGGGATGAC
CCGCATCGACGAGGTGGAGTTCCAGGGGCAGAAGATCGTCCCGATCCAGTTTCTGAAGGCGCTCCTTCCCGATCCCGGCT
CCCTCGGCCCCCTCACCAAGGGGAAGACCTGCATCGGCGTCATTGCCCGGGGGCTCAAGGACGGCAAGCGCAAGCAGGTG
TACATCTACAACATCTGCGACCACGAGGCCTGCTACAAAGAGGTCCAGTCCCAGGCTATCAGCTACACCACCGGCGTTCC
GGCAGTGGTCGGAGCTATTATGATGCTCACCGGCAAGTGGCACGCACCGGGCGTCTGGAACATGGAGCAGTTCGATCCGG
AGGTGTTCCTCAAGGAGCTGGGCCCCATGGGGCTGCCGGAAGTGGCTGTGGAAGGCGAGTGGCCTGAACTGTAG

Upstream 100 bases:

>100_bases
GAGAGGAGAGAGGCCCGCAGGCGTAGCAGCGCTACGTCGAGGAGCCTCTCGACGAGCAGACGTCGTTAGCGCGCGAATAT
GGCGTCGTTCAGGAGGAAAC

Downstream 100 bases:

>100_bases
GAGGAGCGCAATCTTCCGACCATCTCCCCGCCGTCCTCGGAATGCTCGTTGTGCGGCGTAGCGCTGCTACGCCTCCGCCG
GCATCCCTGCGGGTGCGAGG

Product: saccharopine dehydrogenase

Products: L-lysine; 2-oxoglutarate; NADH; H+

Alternate protein names: Carboxynorspermidine Dehydrogenase; Saccharopine Dehydrogenase-Like Protein; Saccharopine Dehydrogenase Family Protein; Acyl Carrier Protein; Carboxynorspermide Hydratase

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MSKVLIIGAGGVGQVVAHKCAQRRDIFSEITLASRTKSKCDAIAAQLNNTIATAQVNADNVPELVALIRKEQPKLVINVA
LPYQDLTIMDACLETGVDYLDTANYEPLDTAKFEYSWQWAYQERFKAAGLMALLGSGFDPGVTNVYTALAAKKYLDEVEE
LDIIDANAGSHGQPFATNFNPEINIREVTAVCRHWENGQFVESPPLSTKRVFDFPEGIGPMNIYRLYHEEMESIVKHIPT
IKKAQFWMTFSDNYLKHLEVLQNVGMTRIDEVEFQGQKIVPIQFLKALLPDPGSLGPLTKGKTCIGVIARGLKDGKRKQV
YIYNICDHEACYKEVQSQAISYTTGVPAVVGAIMMLTGKWHAPGVWNMEQFDPEVFLKELGPMGLPEVAVEGEWPEL

Sequences:

>Translated_397_residues
MSKVLIIGAGGVGQVVAHKCAQRRDIFSEITLASRTKSKCDAIAAQLNNTIATAQVNADNVPELVALIRKEQPKLVINVA
LPYQDLTIMDACLETGVDYLDTANYEPLDTAKFEYSWQWAYQERFKAAGLMALLGSGFDPGVTNVYTALAAKKYLDEVEE
LDIIDANAGSHGQPFATNFNPEINIREVTAVCRHWENGQFVESPPLSTKRVFDFPEGIGPMNIYRLYHEEMESIVKHIPT
IKKAQFWMTFSDNYLKHLEVLQNVGMTRIDEVEFQGQKIVPIQFLKALLPDPGSLGPLTKGKTCIGVIARGLKDGKRKQV
YIYNICDHEACYKEVQSQAISYTTGVPAVVGAIMMLTGKWHAPGVWNMEQFDPEVFLKELGPMGLPEVAVEGEWPEL
>Mature_396_residues
SKVLIIGAGGVGQVVAHKCAQRRDIFSEITLASRTKSKCDAIAAQLNNTIATAQVNADNVPELVALIRKEQPKLVINVAL
PYQDLTIMDACLETGVDYLDTANYEPLDTAKFEYSWQWAYQERFKAAGLMALLGSGFDPGVTNVYTALAAKKYLDEVEEL
DIIDANAGSHGQPFATNFNPEINIREVTAVCRHWENGQFVESPPLSTKRVFDFPEGIGPMNIYRLYHEEMESIVKHIPTI
KKAQFWMTFSDNYLKHLEVLQNVGMTRIDEVEFQGQKIVPIQFLKALLPDPGSLGPLTKGKTCIGVIARGLKDGKRKQVY
IYNICDHEACYKEVQSQAISYTTGVPAVVGAIMMLTGKWHAPGVWNMEQFDPEVFLKELGPMGLPEVAVEGEWPEL

Specific function: Unknown

COG id: COG1748

COG function: function code E; Saccharopine dehydrogenase and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.5.1.7

Molecular weight: Translated: 44172; Mature: 44041

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVLIIGAGGVGQVVAHKCAQRRDIFSEITLASRTKSKCDAIAAQLNNTIATAQVNADN
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
VPELVALIRKEQPKLVINVALPYQDLTIMDACLETGVDYLDTANYEPLDTAKFEYSWQWA
HHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCHHHCCCCCCCCCCEEEEEEEHH
YQERFKAAGLMALLGSGFDPGVTNVYTALAAKKYLDEVEELDIIDANAGSHGQPFATNFN
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCC
PEINIREVTAVCRHWENGQFVESPPLSTKRVFDFPEGIGPMNIYRLYHEEMESIVKHIPT
CCCCHHHHHHHHHHCCCCCEECCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
IKKAQFWMTFSDNYLKHLEVLQNVGMTRIDEVEFQGQKIVPIQFLKALLPDPGSLGPLTK
CCCEEEEEEECHHHHHHHHHHHHCCCCEEEHHHCCCCEECHHHHHHHHCCCCCCCCCCCC
GKTCIGVIARGLKDGKRKQVYIYNICDHEACYKEVQSQAISYTTGVPAVVGAIMMLTGKW
CCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
HAPGVWNMEQFDPEVFLKELGPMGLPEVAVEGEWPEL
CCCCCCCHHHCCHHHHHHHCCCCCCCCEEECCCCCCC
>Mature Secondary Structure 
SKVLIIGAGGVGQVVAHKCAQRRDIFSEITLASRTKSKCDAIAAQLNNTIATAQVNADN
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
VPELVALIRKEQPKLVINVALPYQDLTIMDACLETGVDYLDTANYEPLDTAKFEYSWQWA
HHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCHHHCCCCCCCCCCEEEEEEEHH
YQERFKAAGLMALLGSGFDPGVTNVYTALAAKKYLDEVEELDIIDANAGSHGQPFATNFN
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCC
PEINIREVTAVCRHWENGQFVESPPLSTKRVFDFPEGIGPMNIYRLYHEEMESIVKHIPT
CCCCHHHHHHHHHHCCCCCEECCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
IKKAQFWMTFSDNYLKHLEVLQNVGMTRIDEVEFQGQKIVPIQFLKALLPDPGSLGPLTK
CCCEEEEEEECHHHHHHHHHHHHCCCCEEEHHHCCCCEECHHHHHHHHCCCCCCCCCCCC
GKTCIGVIARGLKDGKRKQVYIYNICDHEACYKEVQSQAISYTTGVPAVVGAIMMLTGKW
CCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
HAPGVWNMEQFDPEVFLKELGPMGLPEVAVEGEWPEL
CCCCCCCHHHCCHHHHHHHCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N6-(L-1,3-dicarboxypropyl)-L-lysine; NAD+; H2O

Specific reaction: N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O = L-lysine + 2-oxoglutarate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA