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The map label for this gene is iorB [H]

Identifier: 78222057

GI number: 78222057

Start: 921938

End: 924112

Strand: Reverse

Name: iorB [H]

Synonym: Gmet_0837

Alternate gene names: 78222057

Gene position: 924112-921938 (Counterclockwise)

Preceding gene: 78222058

Following gene: 78222056

Centisome position: 23.12

GC content: 66.44

Gene sequence:

>2175_bases
ATGAGCGGAATCGTCATCGTGAGCCGCCGTGATTTTCTGAAGGCAGGCATCGTTCTGGGGGGCGGGCTGATCATAGGGGT
CCACCTGCCGGGAGGAACCGCCGCCGGCATGGAGCCCCCCCGCGAGACCTTCGCTCCCGACGCCTTCATCCGGATCGGCA
CCGACGATTCGGTGACGGTGATCGTCAACAAGTCGGAGATGGGCCAGGGGGTCTATACCGCGCTTCCCATGATCGTTGCC
GAGGAACTGGAGGTGGATCCGGCCACCATCCGGGTTGAGGCGGCGCCGGTGACCCCGCCCTACAACCACGCCGAGTGGGG
GATCCAGGCGACCGGTGGCAGCACGAGCGTGCGGTCCGAATGGGACCGTCTCGCAAGAGCGGGGGCAACGGCCCGGATGA
TGCTCGTGGCTGCCGCCGCCGAAACCTGGAAGGTGAAGCCTGGTCAGTGCCGGGCCGAAAAGGGATTTGTCCTCCATCAG
GCCAGCGGCAGGCGCCTCTCCTACGGGAAACTGGCTGAACGGGCCGCCCGGCTGAAGCCCCCGGCGGAGGTGCAGCTGAA
GTCACCCAAGGATTACAGCGTCATCGGCCGGCCGGTCAAACGGCTCGACACTCCTGCCAAAGTGGACGGCACCGCACTCT
TCGGCCTCGATGTCGCCATACCCGGCATGCTCACCGCCGTGGTGGCGCGGCCGCCGGTCTTCGGCGCCAAGGCCATGAAG
ATTCACCATGACAAGGCGGAAAAGGTGCCGGGAGTGAAGAGGGTGATCCCCATCGATGCGGGGGTGGCGGTCATTGCCGA
GAGTTTCCCGGCTGCCGTCAAGGGACGGGAGACCCTGGAAATCGAATGGAACGAAGGGCCCCTGGCAGGCCTCGACAGCG
GCCGCCAGCGGGATGAGTACGCGGAGATGGCAAAACGCCCCGGAGCCGTGGCTGCCCGCCGGGGAGACCCGGACGCCGCG
CTGAAGCAAGCAGTAAAGCGGATCGACGCCGTCTACGAGCTCCCGTACCTGGCCCACGCCCCTCTGGAGCCCTTGAACTG
CGTGGCGAGGGTGGAGCCCGGCCGCTGCGACATCTGGACAGGCACCCAGATGCAGACCGGGGACCGGAACGCGGCGGCAA
AGATCACTGGCCTTCCCCCCGAGAAGATAACCCTCCGCACCATGTTCCTGGGGGGCGGGTTCGGGAGGCGGGCAGTCCCC
GATTCCCACTTCGTGCGGGAAGCGGTGCAGGCATCCAAGGCCATGGGCAAGCCGGTGAAGGTGGTCTGGACCCGGGATGA
CGACATCCACGGCGGCTGGTACCGCCCCACTTTCCATAACGAGCTCTCCGCCGGCCTTGACGCCGCCGGAATGCCCGTTG
CCTGGAAACACCGGATCGTCTGCCAGTCCATCGCCATCGGCACCCCCTTCGAGAAGGGAATGGTGAAAAACGGCGTCGAC
GACACCTCCGTGGAGGGGGCCGCCGATTCACCCTACGCGGTGCCAAACTTCCTCTGCGACTACCACATGGCGCCGGCCGG
AGTGCCGGTCCTCTGGTGGCGGTCGGTGGGGCATTCGGCCACCGCCTTCGTGAAGGAGAGCTTCATCGACGAACTTGCCC
ACCTGGCGGGGAAGGATCCCTATCAGTACCGCCGGCAACTCCTGGGGAAGCATCCGCGACTCGTGGGAGCCCTGGACCTG
GCTACGGAAAAGGCTGGGTGGGGAAAAGCGCTGCCCGAGGGGCGGGGACGGGGAATCGCCGTCCATGAGTCCTTCGGGAG
CATCGTGGCCCAGGTGGCAGAGGTATCGGTCGGTGCGAAAGGAGAAATCCGGGTGCACCGGGTCGTCTGCGCCGTGGATT
GCGGCCGGTTCGTGAATCCCGGCATCATCGAGGCCCAGATGGAGTCGGGGATCGCCTTCGGCCTCTCGGCGGCCCTTCAC
GGAGCCATCACCTTCAAGAACGGCCGGGTGGAGCAGTCCAACTACCATGACTACCCCATCATCCGGATGAATGAGATGCC
CCGGGTGGAGACCCACATTGTCCGGAACGGGGAGAAGCCGGGAGGGATCGGCGAGCCGGGAGTCCCGCCAGTGGCTCCTG
CCGTGGCTAACGCCCTGTTCGCCCTCACCGGAGCCCGCCTGCGGACCCTGCCGATGACGCCGGAACGGGTTCTGGCTGCA
ACGGGCAAGACATGA

Upstream 100 bases:

>100_bases
ACGAGGCCATGGAGGGAATCCTCTGCCGATGCGGCACCTACCAGCGCATCCGCCGGGCAATCCACCGGGCCGCCGGCACG
CCGGCGAAAGGGGGTGCGTC

Downstream 100 bases:

>100_bases
ACGTCGCCGCAATCCTTCTGGCTGCCGGCAAGTCGCAACGGATGGGACTCTGCAAACAACTCCTGCAGCTTGCCGACCGC
CCCGCCGTGGCCCATTGCCT

Product: twin-arginine translocation pathway signal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 724; Mature: 723

Protein sequence:

>724_residues
MSGIVIVSRRDFLKAGIVLGGGLIIGVHLPGGTAAGMEPPRETFAPDAFIRIGTDDSVTVIVNKSEMGQGVYTALPMIVA
EELEVDPATIRVEAAPVTPPYNHAEWGIQATGGSTSVRSEWDRLARAGATARMMLVAAAAETWKVKPGQCRAEKGFVLHQ
ASGRRLSYGKLAERAARLKPPAEVQLKSPKDYSVIGRPVKRLDTPAKVDGTALFGLDVAIPGMLTAVVARPPVFGAKAMK
IHHDKAEKVPGVKRVIPIDAGVAVIAESFPAAVKGRETLEIEWNEGPLAGLDSGRQRDEYAEMAKRPGAVAARRGDPDAA
LKQAVKRIDAVYELPYLAHAPLEPLNCVARVEPGRCDIWTGTQMQTGDRNAAAKITGLPPEKITLRTMFLGGGFGRRAVP
DSHFVREAVQASKAMGKPVKVVWTRDDDIHGGWYRPTFHNELSAGLDAAGMPVAWKHRIVCQSIAIGTPFEKGMVKNGVD
DTSVEGAADSPYAVPNFLCDYHMAPAGVPVLWWRSVGHSATAFVKESFIDELAHLAGKDPYQYRRQLLGKHPRLVGALDL
ATEKAGWGKALPEGRGRGIAVHESFGSIVAQVAEVSVGAKGEIRVHRVVCAVDCGRFVNPGIIEAQMESGIAFGLSAALH
GAITFKNGRVEQSNYHDYPIIRMNEMPRVETHIVRNGEKPGGIGEPGVPPVAPAVANALFALTGARLRTLPMTPERVLAA
TGKT

Sequences:

>Translated_724_residues
MSGIVIVSRRDFLKAGIVLGGGLIIGVHLPGGTAAGMEPPRETFAPDAFIRIGTDDSVTVIVNKSEMGQGVYTALPMIVA
EELEVDPATIRVEAAPVTPPYNHAEWGIQATGGSTSVRSEWDRLARAGATARMMLVAAAAETWKVKPGQCRAEKGFVLHQ
ASGRRLSYGKLAERAARLKPPAEVQLKSPKDYSVIGRPVKRLDTPAKVDGTALFGLDVAIPGMLTAVVARPPVFGAKAMK
IHHDKAEKVPGVKRVIPIDAGVAVIAESFPAAVKGRETLEIEWNEGPLAGLDSGRQRDEYAEMAKRPGAVAARRGDPDAA
LKQAVKRIDAVYELPYLAHAPLEPLNCVARVEPGRCDIWTGTQMQTGDRNAAAKITGLPPEKITLRTMFLGGGFGRRAVP
DSHFVREAVQASKAMGKPVKVVWTRDDDIHGGWYRPTFHNELSAGLDAAGMPVAWKHRIVCQSIAIGTPFEKGMVKNGVD
DTSVEGAADSPYAVPNFLCDYHMAPAGVPVLWWRSVGHSATAFVKESFIDELAHLAGKDPYQYRRQLLGKHPRLVGALDL
ATEKAGWGKALPEGRGRGIAVHESFGSIVAQVAEVSVGAKGEIRVHRVVCAVDCGRFVNPGIIEAQMESGIAFGLSAALH
GAITFKNGRVEQSNYHDYPIIRMNEMPRVETHIVRNGEKPGGIGEPGVPPVAPAVANALFALTGARLRTLPMTPERVLAA
TGKT
>Mature_723_residues
SGIVIVSRRDFLKAGIVLGGGLIIGVHLPGGTAAGMEPPRETFAPDAFIRIGTDDSVTVIVNKSEMGQGVYTALPMIVAE
ELEVDPATIRVEAAPVTPPYNHAEWGIQATGGSTSVRSEWDRLARAGATARMMLVAAAAETWKVKPGQCRAEKGFVLHQA
SGRRLSYGKLAERAARLKPPAEVQLKSPKDYSVIGRPVKRLDTPAKVDGTALFGLDVAIPGMLTAVVARPPVFGAKAMKI
HHDKAEKVPGVKRVIPIDAGVAVIAESFPAAVKGRETLEIEWNEGPLAGLDSGRQRDEYAEMAKRPGAVAARRGDPDAAL
KQAVKRIDAVYELPYLAHAPLEPLNCVARVEPGRCDIWTGTQMQTGDRNAAAKITGLPPEKITLRTMFLGGGFGRRAVPD
SHFVREAVQASKAMGKPVKVVWTRDDDIHGGWYRPTFHNELSAGLDAAGMPVAWKHRIVCQSIAIGTPFEKGMVKNGVDD
TSVEGAADSPYAVPNFLCDYHMAPAGVPVLWWRSVGHSATAFVKESFIDELAHLAGKDPYQYRRQLLGKHPRLVGALDLA
TEKAGWGKALPEGRGRGIAVHESFGSIVAQVAEVSVGAKGEIRVHRVVCAVDCGRFVNPGIIEAQMESGIAFGLSAALHG
AITFKNGRVEQSNYHDYPIIRMNEMPRVETHIVRNGEKPGGIGEPGVPPVAPAVANALFALTGARLRTLPMTPERVLAAT
GKT

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786478, Length=401, Percent_Identity=25.9351620947631, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789230, Length=126, Percent_Identity=31.7460317460317, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 77423; Mature: 77292

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGIVIVSRRDFLKAGIVLGGGLIIGVHLPGGTAAGMEPPRETFAPDAFIRIGTDDSVTV
CCCEEEEECCHHHHHHHEEECCEEEEEECCCCCCCCCCCCHHHCCCCCEEEECCCCCEEE
IVNKSEMGQGVYTALPMIVAEELEVDPATIRVEAAPVTPPYNHAEWGIQATGGSTSVRSE
EEECHHCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCEEECCCCCHHHHH
WDRLARAGATARMMLVAAAAETWKVKPGQCRAEKGFVLHQASGRRLSYGKLAERAARLKP
HHHHHHCCCHHHHHEEEEHHHHCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCC
PAEVQLKSPKDYSVIGRPVKRLDTPAKVDGTALFGLDVAIPGMLTAVVARPPVFGAKAMK
CCCEEECCCCCCHHHCCCHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCEEE
IHHDKAEKVPGVKRVIPIDAGVAVIAESFPAAVKGRETLEIEWNEGPLAGLDSGRQRDEY
EECCHHHHCCCCEEEEECCCCHHHHHHHCCHHHCCCEEEEEEECCCCCCCCCCCCCHHHH
AEMAKRPGAVAARRGDPDAALKQAVKRIDAVYELPYLAHAPLEPLNCVARVEPGRCDIWT
HHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHEEEECCCCEEEEC
GTQMQTGDRNAAAKITGLPPEKITLRTMFLGGGFGRRAVPDSHFVREAVQASKAMGKPVK
CCCCCCCCCCCCEEEECCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEE
VVWTRDDDIHGGWYRPTFHNELSAGLDAAGMPVAWKHRIVCQSIAIGTPFEKGMVKNGVD
EEEECCCCCCCCEECCCCHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCC
DTSVEGAADSPYAVPNFLCDYHMAPAGVPVLWWRSVGHSATAFVKESFIDELAHLAGKDP
CCCCCCCCCCCCCCHHHHHHCCCCCCCCCEEEEHHCCCCHHHHHHHHHHHHHHHHHCCCH
YQYRRQLLGKHPRLVGALDLATEKAGWGKALPEGRGRGIAVHESFGSIVAQVAEVSVGAK
HHHHHHHHCCCCCEEEEHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCC
GEIRVHRVVCAVDCGRFVNPGIIEAQMESGIAFGLSAALHGAITFKNGRVEQSNYHDYPI
CCEEEEEEEEEECCCCCCCCCEEEHHHHCCHHHHHHHHHEEEEEECCCEEECCCCCCCCE
IRMNEMPRVETHIVRNGEKPGGIGEPGVPPVAPAVANALFALTGARLRTLPMTPERVLAA
EEECCCCCHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCHHHHHHC
TGKT
CCCC
>Mature Secondary Structure 
SGIVIVSRRDFLKAGIVLGGGLIIGVHLPGGTAAGMEPPRETFAPDAFIRIGTDDSVTV
CCEEEEECCHHHHHHHEEECCEEEEEECCCCCCCCCCCCHHHCCCCCEEEECCCCCEEE
IVNKSEMGQGVYTALPMIVAEELEVDPATIRVEAAPVTPPYNHAEWGIQATGGSTSVRSE
EEECHHCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCEEECCCCCHHHHH
WDRLARAGATARMMLVAAAAETWKVKPGQCRAEKGFVLHQASGRRLSYGKLAERAARLKP
HHHHHHCCCHHHHHEEEEHHHHCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCC
PAEVQLKSPKDYSVIGRPVKRLDTPAKVDGTALFGLDVAIPGMLTAVVARPPVFGAKAMK
CCCEEECCCCCCHHHCCCHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCEEE
IHHDKAEKVPGVKRVIPIDAGVAVIAESFPAAVKGRETLEIEWNEGPLAGLDSGRQRDEY
EECCHHHHCCCCEEEEECCCCHHHHHHHCCHHHCCCEEEEEEECCCCCCCCCCCCCHHHH
AEMAKRPGAVAARRGDPDAALKQAVKRIDAVYELPYLAHAPLEPLNCVARVEPGRCDIWT
HHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHEEEECCCCEEEEC
GTQMQTGDRNAAAKITGLPPEKITLRTMFLGGGFGRRAVPDSHFVREAVQASKAMGKPVK
CCCCCCCCCCCCEEEECCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEE
VVWTRDDDIHGGWYRPTFHNELSAGLDAAGMPVAWKHRIVCQSIAIGTPFEKGMVKNGVD
EEEECCCCCCCCEECCCCHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCC
DTSVEGAADSPYAVPNFLCDYHMAPAGVPVLWWRSVGHSATAFVKESFIDELAHLAGKDP
CCCCCCCCCCCCCCHHHHHHCCCCCCCCCEEEEHHCCCCHHHHHHHHHHHHHHHHHCCCH
YQYRRQLLGKHPRLVGALDLATEKAGWGKALPEGRGRGIAVHESFGSIVAQVAEVSVGAK
HHHHHHHHCCCCCEEEEHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCC
GEIRVHRVVCAVDCGRFVNPGIIEAQMESGIAFGLSAALHGAITFKNGRVEQSNYHDYPI
CCEEEEEEEEEECCCCCCCCCEEEHHHHCCHHHHHHHHHEEEEEECCCEEECCCCCCCCE
IRMNEMPRVETHIVRNGEKPGGIGEPGVPPVAPAVANALFALTGARLRTLPMTPERVLAA
EEECCCCCHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCHHHHHHC
TGKT
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]