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The map label for this gene is pyc [H]

Identifier: 78222036

GI number: 78222036

Start: 899262

End: 902708

Strand: Direct

Name: pyc [H]

Synonym: Gmet_0816

Alternate gene names: 78222036

Gene position: 899262-902708 (Clockwise)

Preceding gene: 78222034

Following gene: 78222037

Centisome position: 22.5

GC content: 62.63

Gene sequence:

>3447_bases
ATGGAGAAGAGAAAGTTCAGGAAGGTAATGGCCGCCAACCGCGGCGAGATTGCGATTCGTATTTTCCGGGCCTGCACGGA
GCTCGGGATCAGCACCGTTGCCATATACTCGGAGGAGGATAAGCTGTCGCTCCACCGTTACAAGGCCGACGAGGCATATC
TGGTGGGGAAGGGGAAGAATCCCATCGACGCCTATCTTGGTATCGACGAGATCATCGCCATCGCCAAGAAGTATGACGTG
GACGCCATCCATCCCGGCTACGGCTTCCTCTCGGAGAACGCCGAGTTCGCCGAGAAGTGCGAAGCGTCGGGGATCGCCTT
CATCGGCCCCACGGCCGAGATGCAGCGTGCCCTGGGGGACAAGGTGTCGGCCCGCAAGGTGGCCATGGCCGCCGGCGTCA
CCACCGTCCCCGGCACCGAGGACCCCATCGAGCACGAGGAAGAGGCCCTCATCTTCGCCAAGAACTACGGCTACCCCATC
ATCATCAAGGCGGCGGCCGGTGGCGGCGGGCGCGGCATGCGGGTGGCCCGGACCAAGAAGGAGCTCCTCGAAGGGCTCGT
GGCGGCCCGCAGCGAGGCCAAGGCGGCCTTCGGCAACCCAGCGGTCTTCCTGGAGCGCTACATTGAGAATCCGAAGCATA
TCGAGGTGCAGGTCCTGGGCGACATGCACGGCAACCTGGTCCACTTCTTCGAGCGGGACTGCTCCATCCAGCGCCGCCAC
CAGAAGGTGGTGGAATTCGCCCCGGCCCTCTGCCTGAGCCAGGAGACCCGCGAGGCGATCTGCGCCGCGGCCCTCAAGAT
CGCCGGCCAGGTGGGATACCGCAATGCCGGTACTGTCGAGTTCCTCCTGGACCAGGAGGGGAACTTCTTCTTCATCGAGA
TGAACCCCCGTATCCAGGTGGAGCACACGGTGACCGAAATGATCACCGGCCGCAACCTGGTCCAGGCCCAGATCCTCGTG
GCCGAGGGGAAAAAACTCTCCGATGCCCCCATCAACATCCCCAACCAGGAAGCCATCGCCATGCGGGGGTACGCCATCCA
GTGCCGGATCACCACCGAGGACCCGAACAACAACTTCGCCCCGGACTTCGGCACCATCACCACCTATCGCTCCTCGGCGG
GTTTTGGAGTGCGGCTCGACGCCGGCAACGCCTTTACCGGTTCGGTGATCACTCCCCACTATGACTCGCTCCTCGTGAAG
GTCACCTCCTGGGGGCTCACCTTCGACGAAGCAGCCCACATCATGAACCGCTCGCTCCAGGAATTCCGGGTCCGGGGGGT
CAAGACCAACATCGGCTTCCTGGAGAACGTCATCACCCACCGGGTCTTCCTCGACGGCAAGTGTGATACCTCCTTCATCG
AGAAACACTCGGAACTGCTGCAGATTATCGAGAAGAAGGACCGGGCCACGAAGGTTCTCAGCTTCCTCGGTGACGTCATC
GTCAACGGTTCGCCGGGAATCACGAAGCCCCTCAAGTCGGCGGAGCTCATGGAGGCCCATGTGCCGGAGGTGGATCTCAC
CCAGCCCCGCCCCGCCGGGAGCCGCGACCTCCTCATGAAGCTCGGGGCCGAAGGGCTCTCCAAGTGGATCCTTGAGCAGA
AGAAGCTTCTCATCACCGACACCACCATGCGTGACGCCCACCAGTCGAACCTAGCCACCCGGGTCCGCACCTATGATCTC
CTGAAGATTGCCGAGCCCACTTCCTATCTCGGTGCCGGGCTTTTCTCCATCGAGTGCTGGGGGGGCGCCACCTTCGACGT
CTCCATGCGCTTCCTGAAGGAAGACCCGTGGCAGCGGCTCCACAAGCTCTCGGAAGCGATCCCCAACGTTCTCTTCCAGA
TGCTCCTGCGGGGCTCCAACGCCGTGGGGTACACCAACTACCCGGACAACGTGGTGCAGCGCTTCGTGGAGGAGGCGGCC
TCCTCCGGCATAGACATCTTCCGGGTCTTCGACTCCCTCAACTGGACCCGCGGCATGGCCGTAGCCATGGAGGCGGTCCG
CAAGAGCGGCAAGATCTGCGAGGCGGCCATCTGCTACACCGGCGACATCACCGATCCGACCCGGGACAAGTATCCCCTGG
AATACTACGTGAACATGGCCAAGGAACTGGAGCAGATGGGGGCCCACATCCTCGCCATCAAGGACATGGCTGGCCTCCTG
AAGCCCTTCGCCGCCTACAAACTGGTGAAGGCCCTCAAGGAGAACATCGGCATCCCGGTCCACCTCCATACTCACGACAC
CTCCTCCAATGGGAGCGCCACGCTCCTCATGGCCTGCCAGGCAGGGGTCGACATCGTCGACGCGGCCCTGTCGTCCCTGT
CGGGGCTCACGGCCCAACCGAACCTGAACGCCTTGGTGGCGGCCCTGAAGGGGACCGAGTGGGACACCCGGCTGGATGAG
GACGGGCTCCAGAAACTGGCCAACTACTGGGAGACGGTGCGCGACTACTACGCCCCCTTCGAGTCAGGGCTCAAGAACGG
CACCGCCGAGGTCTACCACCACGAGATTCCCGGCGGCCAGTACTCCAACTACAAGCCCCAGGTGGCCGGCCTCGGCCTCC
TGGATCGCTGGGAGGAGTGCAAGGAGATGTACCACAAGGTGAACCTCCTCTTCGGCGACATCGTGAAGGTCACGCCGTCC
TCCAAGGTGGTGGGGGATATGGCCATGTTCCTCGTGAAGAACAACCTGGATGTACAGGATGTCTTTACACAGGGTGATGA
GCTTGCCTTCCCCGAGTCGGTCATCGGGATGTTCAAGGGGATGCTGGGCCAGCCTTACCAGGGATGGCCCCGGGAACTCC
AGAAGATCATCCTGAAGGGAGATGAGCCCATCACCTGCCGCCCCGGCGAACTCCTGGAGCCGGCCAATTTCGACGAGGAG
CGGGACAAGGTGGAGGAGAAGGTCGGCCACGCCGTGGACGACAAGGCGCTCATGAGCTACATCATGTACCCCCACGTCTA
CCCGGAGTTCCACAAGCACCGCCATGAGTACTCCGACACCTCGGTCATCCCGACCCCCATCTTCTTCTACGGCCTGGAGC
CGGGGCAGGAGACCTCCATCGAGATCGAGGCGGGCAAGACCCTCATCATCAAGCTGAACGCCATCGGCAAGGTCCACCCC
GACGGCACCCGGCACATCTTCTTCGAGCTGAACGGCAATGCCCGGAGCGTGGTGGTACGCGACCAGTCGGTTCAGACCGA
CGAGTCGGTGCGCGAGAAGGCCGACAAGGGGAACGCCAAGCACGTGGGGGCGCCGATGCCGGGGAAGGTCCTGAAGCTCA
ACGTCAAGGTGGGCGACGAGGTCAAGGCCGGCGATGTCCTCATGGTCACCGAGGCCATGAAGATGGAGACCAACATCAAA
GCCAAGGAGGACGGCATCGTCGCCGAGGTGAAGTTCAAGGAAGGCGACAAGGTGGAGAAGGAGGATCTTCTCATCGTTAT
GGGGTAA

Upstream 100 bases:

>100_bases
GCGCATAACTATTCAAAATAACGAAATAATTTTAGTTTGAATAAAGTTTTATCTTGCTTGTAGATGTTTTATTTTACGTA
AAAACACTGGGGAGGACCGG

Downstream 100 bases:

>100_bases
ACCGCTCCTAACGGAAAACACTCGAAACCGCCGCGGTAACGTGGTATTAAAGGGGGGCCGCCCATGAGGCGGTTCCCCTT
TTTCTATAACGGGAATTTAG

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1148; Mature: 1148

Protein sequence:

>1148_residues
MEKRKFRKVMAANRGEIAIRIFRACTELGISTVAIYSEEDKLSLHRYKADEAYLVGKGKNPIDAYLGIDEIIAIAKKYDV
DAIHPGYGFLSENAEFAEKCEASGIAFIGPTAEMQRALGDKVSARKVAMAAGVTTVPGTEDPIEHEEEALIFAKNYGYPI
IIKAAAGGGGRGMRVARTKKELLEGLVAARSEAKAAFGNPAVFLERYIENPKHIEVQVLGDMHGNLVHFFERDCSIQRRH
QKVVEFAPALCLSQETREAICAAALKIAGQVGYRNAGTVEFLLDQEGNFFFIEMNPRIQVEHTVTEMITGRNLVQAQILV
AEGKKLSDAPINIPNQEAIAMRGYAIQCRITTEDPNNNFAPDFGTITTYRSSAGFGVRLDAGNAFTGSVITPHYDSLLVK
VTSWGLTFDEAAHIMNRSLQEFRVRGVKTNIGFLENVITHRVFLDGKCDTSFIEKHSELLQIIEKKDRATKVLSFLGDVI
VNGSPGITKPLKSAELMEAHVPEVDLTQPRPAGSRDLLMKLGAEGLSKWILEQKKLLITDTTMRDAHQSNLATRVRTYDL
LKIAEPTSYLGAGLFSIECWGGATFDVSMRFLKEDPWQRLHKLSEAIPNVLFQMLLRGSNAVGYTNYPDNVVQRFVEEAA
SSGIDIFRVFDSLNWTRGMAVAMEAVRKSGKICEAAICYTGDITDPTRDKYPLEYYVNMAKELEQMGAHILAIKDMAGLL
KPFAAYKLVKALKENIGIPVHLHTHDTSSNGSATLLMACQAGVDIVDAALSSLSGLTAQPNLNALVAALKGTEWDTRLDE
DGLQKLANYWETVRDYYAPFESGLKNGTAEVYHHEIPGGQYSNYKPQVAGLGLLDRWEECKEMYHKVNLLFGDIVKVTPS
SKVVGDMAMFLVKNNLDVQDVFTQGDELAFPESVIGMFKGMLGQPYQGWPRELQKIILKGDEPITCRPGELLEPANFDEE
RDKVEEKVGHAVDDKALMSYIMYPHVYPEFHKHRHEYSDTSVIPTPIFFYGLEPGQETSIEIEAGKTLIIKLNAIGKVHP
DGTRHIFFELNGNARSVVVRDQSVQTDESVREKADKGNAKHVGAPMPGKVLKLNVKVGDEVKAGDVLMVTEAMKMETNIK
AKEDGIVAEVKFKEGDKVEKEDLLIVMG

Sequences:

>Translated_1148_residues
MEKRKFRKVMAANRGEIAIRIFRACTELGISTVAIYSEEDKLSLHRYKADEAYLVGKGKNPIDAYLGIDEIIAIAKKYDV
DAIHPGYGFLSENAEFAEKCEASGIAFIGPTAEMQRALGDKVSARKVAMAAGVTTVPGTEDPIEHEEEALIFAKNYGYPI
IIKAAAGGGGRGMRVARTKKELLEGLVAARSEAKAAFGNPAVFLERYIENPKHIEVQVLGDMHGNLVHFFERDCSIQRRH
QKVVEFAPALCLSQETREAICAAALKIAGQVGYRNAGTVEFLLDQEGNFFFIEMNPRIQVEHTVTEMITGRNLVQAQILV
AEGKKLSDAPINIPNQEAIAMRGYAIQCRITTEDPNNNFAPDFGTITTYRSSAGFGVRLDAGNAFTGSVITPHYDSLLVK
VTSWGLTFDEAAHIMNRSLQEFRVRGVKTNIGFLENVITHRVFLDGKCDTSFIEKHSELLQIIEKKDRATKVLSFLGDVI
VNGSPGITKPLKSAELMEAHVPEVDLTQPRPAGSRDLLMKLGAEGLSKWILEQKKLLITDTTMRDAHQSNLATRVRTYDL
LKIAEPTSYLGAGLFSIECWGGATFDVSMRFLKEDPWQRLHKLSEAIPNVLFQMLLRGSNAVGYTNYPDNVVQRFVEEAA
SSGIDIFRVFDSLNWTRGMAVAMEAVRKSGKICEAAICYTGDITDPTRDKYPLEYYVNMAKELEQMGAHILAIKDMAGLL
KPFAAYKLVKALKENIGIPVHLHTHDTSSNGSATLLMACQAGVDIVDAALSSLSGLTAQPNLNALVAALKGTEWDTRLDE
DGLQKLANYWETVRDYYAPFESGLKNGTAEVYHHEIPGGQYSNYKPQVAGLGLLDRWEECKEMYHKVNLLFGDIVKVTPS
SKVVGDMAMFLVKNNLDVQDVFTQGDELAFPESVIGMFKGMLGQPYQGWPRELQKIILKGDEPITCRPGELLEPANFDEE
RDKVEEKVGHAVDDKALMSYIMYPHVYPEFHKHRHEYSDTSVIPTPIFFYGLEPGQETSIEIEAGKTLIIKLNAIGKVHP
DGTRHIFFELNGNARSVVVRDQSVQTDESVREKADKGNAKHVGAPMPGKVLKLNVKVGDEVKAGDVLMVTEAMKMETNIK
AKEDGIVAEVKFKEGDKVEKEDLLIVMG
>Mature_1148_residues
MEKRKFRKVMAANRGEIAIRIFRACTELGISTVAIYSEEDKLSLHRYKADEAYLVGKGKNPIDAYLGIDEIIAIAKKYDV
DAIHPGYGFLSENAEFAEKCEASGIAFIGPTAEMQRALGDKVSARKVAMAAGVTTVPGTEDPIEHEEEALIFAKNYGYPI
IIKAAAGGGGRGMRVARTKKELLEGLVAARSEAKAAFGNPAVFLERYIENPKHIEVQVLGDMHGNLVHFFERDCSIQRRH
QKVVEFAPALCLSQETREAICAAALKIAGQVGYRNAGTVEFLLDQEGNFFFIEMNPRIQVEHTVTEMITGRNLVQAQILV
AEGKKLSDAPINIPNQEAIAMRGYAIQCRITTEDPNNNFAPDFGTITTYRSSAGFGVRLDAGNAFTGSVITPHYDSLLVK
VTSWGLTFDEAAHIMNRSLQEFRVRGVKTNIGFLENVITHRVFLDGKCDTSFIEKHSELLQIIEKKDRATKVLSFLGDVI
VNGSPGITKPLKSAELMEAHVPEVDLTQPRPAGSRDLLMKLGAEGLSKWILEQKKLLITDTTMRDAHQSNLATRVRTYDL
LKIAEPTSYLGAGLFSIECWGGATFDVSMRFLKEDPWQRLHKLSEAIPNVLFQMLLRGSNAVGYTNYPDNVVQRFVEEAA
SSGIDIFRVFDSLNWTRGMAVAMEAVRKSGKICEAAICYTGDITDPTRDKYPLEYYVNMAKELEQMGAHILAIKDMAGLL
KPFAAYKLVKALKENIGIPVHLHTHDTSSNGSATLLMACQAGVDIVDAALSSLSGLTAQPNLNALVAALKGTEWDTRLDE
DGLQKLANYWETVRDYYAPFESGLKNGTAEVYHHEIPGGQYSNYKPQVAGLGLLDRWEECKEMYHKVNLLFGDIVKVTPS
SKVVGDMAMFLVKNNLDVQDVFTQGDELAFPESVIGMFKGMLGQPYQGWPRELQKIILKGDEPITCRPGELLEPANFDEE
RDKVEEKVGHAVDDKALMSYIMYPHVYPEFHKHRHEYSDTSVIPTPIFFYGLEPGQETSIEIEAGKTLIIKLNAIGKVHP
DGTRHIFFELNGNARSVVVRDQSVQTDESVREKADKGNAKHVGAPMPGKVLKLNVKVGDEVKAGDVLMVTEAMKMETNIK
AKEDGIVAEVKFKEGDKVEKEDLLIVMG

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1149, Percent_Identity=50.4786771105309, Blast_Score=1123, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1149, Percent_Identity=50.4786771105309, Blast_Score=1123, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1149, Percent_Identity=50.4786771105309, Blast_Score=1123, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=463, Percent_Identity=43.6285097192225, Blast_Score=390, Evalue=1e-108,
Organism=Homo sapiens, GI65506442, Length=453, Percent_Identity=44.3708609271523, Blast_Score=368, Evalue=1e-101,
Organism=Homo sapiens, GI189095269, Length=452, Percent_Identity=44.4690265486726, Blast_Score=368, Evalue=1e-101,
Organism=Homo sapiens, GI295821183, Length=453, Percent_Identity=44.3708609271523, Blast_Score=368, Evalue=1e-101,
Organism=Homo sapiens, GI134142062, Length=508, Percent_Identity=33.8582677165354, Blast_Score=243, Evalue=5e-64,
Organism=Homo sapiens, GI38679977, Length=531, Percent_Identity=31.638418079096, Blast_Score=242, Evalue=2e-63,
Organism=Homo sapiens, GI38679967, Length=531, Percent_Identity=31.638418079096, Blast_Score=242, Evalue=2e-63,
Organism=Homo sapiens, GI38679960, Length=531, Percent_Identity=31.638418079096, Blast_Score=242, Evalue=2e-63,
Organism=Homo sapiens, GI38679971, Length=531, Percent_Identity=31.638418079096, Blast_Score=242, Evalue=2e-63,
Organism=Homo sapiens, GI38679974, Length=531, Percent_Identity=31.638418079096, Blast_Score=241, Evalue=2e-63,
Organism=Escherichia coli, GI1789654, Length=449, Percent_Identity=47.6614699331849, Blast_Score=377, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17562816, Length=1151, Percent_Identity=52.0417028670721, Blast_Score=1188, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987519, Length=460, Percent_Identity=42.8260869565217, Blast_Score=355, Evalue=1e-97,
Organism=Caenorhabditis elegans, GI17567343, Length=451, Percent_Identity=41.6851441241685, Blast_Score=343, Evalue=4e-94,
Organism=Caenorhabditis elegans, GI71997163, Length=505, Percent_Identity=30.8910891089109, Blast_Score=222, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI71997168, Length=505, Percent_Identity=30.8910891089109, Blast_Score=221, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI133931226, Length=494, Percent_Identity=31.5789473684211, Blast_Score=217, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1154, Percent_Identity=49.2201039861352, Blast_Score=1106, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1154, Percent_Identity=49.5667244367418, Blast_Score=1096, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=452, Percent_Identity=39.3805309734513, Blast_Score=319, Evalue=2e-87,
Organism=Saccharomyces cerevisiae, GI6323863, Length=451, Percent_Identity=33.9246119733925, Blast_Score=226, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6324343, Length=511, Percent_Identity=31.5068493150685, Blast_Score=226, Evalue=1e-59,
Organism=Drosophila melanogaster, GI24652212, Length=1152, Percent_Identity=50.9548611111111, Blast_Score=1155, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1152, Percent_Identity=50.9548611111111, Blast_Score=1155, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1152, Percent_Identity=50.9548611111111, Blast_Score=1155, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1152, Percent_Identity=50.9548611111111, Blast_Score=1155, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1152, Percent_Identity=50.9548611111111, Blast_Score=1155, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1169, Percent_Identity=50.3849443969205, Blast_Score=1149, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1169, Percent_Identity=50.3849443969205, Blast_Score=1149, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1169, Percent_Identity=50.3849443969205, Blast_Score=1149, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1169, Percent_Identity=50.3849443969205, Blast_Score=1149, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1169, Percent_Identity=50.3849443969205, Blast_Score=1149, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=459, Percent_Identity=41.3943355119826, Blast_Score=360, Evalue=5e-99,
Organism=Drosophila melanogaster, GI24651759, Length=419, Percent_Identity=41.0501193317422, Blast_Score=321, Evalue=2e-87,
Organism=Drosophila melanogaster, GI24586458, Length=507, Percent_Identity=32.3471400394477, Blast_Score=236, Evalue=5e-62,
Organism=Drosophila melanogaster, GI161076409, Length=507, Percent_Identity=32.3471400394477, Blast_Score=236, Evalue=6e-62,
Organism=Drosophila melanogaster, GI161076407, Length=507, Percent_Identity=32.3471400394477, Blast_Score=236, Evalue=7e-62,
Organism=Drosophila melanogaster, GI24586460, Length=507, Percent_Identity=32.3471400394477, Blast_Score=236, Evalue=7e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 127098; Mature: 127098

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKRKFRKVMAANRGEIAIRIFRACTELGISTVAIYSEEDKLSLHRYKADEAYLVGKGKN
CCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCEEEEECCCC
PIDAYLGIDEIIAIAKKYDVDAIHPGYGFLSENAEFAEKCEASGIAFIGPTAEMQRALGD
CHHHHCCHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHCCEEEECCHHHHHHHHCC
KVSARKVAMAAGVTTVPGTEDPIEHEEEALIFAKNYGYPIIIKAAAGGGGRGMRVARTKK
CHHHHHHHHHCCCEECCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCHHHHHH
ELLEGLVAARSEAKAAFGNPAVFLERYIENPKHIEVQVLGDMHGNLVHFFERDCSIQRRH
HHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHCCHHHHHH
QKVVEFAPALCLSQETREAICAAALKIAGQVGYRNAGTVEFLLDQEGNFFFIEMNPRIQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEECCCEEE
EHTVTEMITGRNLVQAQILVAEGKKLSDAPINIPNQEAIAMRGYAIQCRITTEDPNNNFA
HHHHHHHHCCCCHHEEEEEEECCCCCCCCCCCCCCCCEEEECCEEEEEEEEECCCCCCCC
PDFGTITTYRSSAGFGVRLDAGNAFTGSVITPHYDSLLVKVTSWGLTFDEAAHIMNRSLQ
CCCCCEEEEECCCCCEEEEECCCCEECCCCCCCHHHEEEEEEECCCCHHHHHHHHHHHHH
EFRVRGVKTNIGFLENVITHRVFLDGKCDTSFIEKHSELLQIIEKKDRATKVLSFLGDVI
HHHHCCCCCCHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
VNGSPGITKPLKSAELMEAHVPEVDLTQPRPAGSRDLLMKLGAEGLSKWILEQKKLLITD
ECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHCCCEEEEE
TTMRDAHQSNLATRVRTYDLLKIAEPTSYLGAGLFSIECWGGATFDVSMRFLKEDPWQRL
CHHHHHHHHHHHHHHHHHHHHEECCCHHHHCCCEEEEEECCCCEEHHHHHHHHCCHHHHH
HKLSEAIPNVLFQMLLRGSNAVGYTNYPDNVVQRFVEEAASSGIDIFRVFDSLNWTRGMA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEHHHHCCCCHHHHH
VAMEAVRKSGKICEAAICYTGDITDPTRDKYPLEYYVNMAKELEQMGAHILAIKDMAGLL
HHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHH
KPFAAYKLVKALKENIGIPVHLHTHDTSSNGSATLLMACQAGVDIVDAALSSLSGLTAQP
HHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCC
NLNALVAALKGTEWDTRLDEDGLQKLANYWETVRDYYAPFESGLKNGTAEVYHHEIPGGQ
CHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
YSNYKPQVAGLGLLDRWEECKEMYHKVNLLFGDIVKVTPSSKVVGDMAMFLVKNNLDVQD
CCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHCCCCHHH
VFTQGDELAFPESVIGMFKGMLGQPYQGWPRELQKIILKGDEPITCRPGELLEPANFDEE
HHCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCCCHH
RDKVEEKVGHAVDDKALMSYIMYPHVYPEFHKHRHEYSDTSVIPTPIFFYGLEPGQETSI
HHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCEE
EIEAGKTLIIKLNAIGKVHPDGTRHIFFELNGNARSVVVRDQSVQTDESVREKADKGNAK
EEECCCEEEEEEECCCCCCCCCCEEEEEEECCCEEEEEEECCCCCCHHHHHHHHHCCCCC
HVGAPMPGKVLKLNVKVGDEVKAGDVLMVTEAMKMETNIKAKEDGIVAEVKFKEGDKVEK
CCCCCCCCCEEEEEEEECCCCCCCCEEEEEHHHHHHCCCCCCCCCEEEEEEECCCCCCCC
EDLLIVMG
CCEEEEEC
>Mature Secondary Structure
MEKRKFRKVMAANRGEIAIRIFRACTELGISTVAIYSEEDKLSLHRYKADEAYLVGKGKN
CCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCEEEEECCCC
PIDAYLGIDEIIAIAKKYDVDAIHPGYGFLSENAEFAEKCEASGIAFIGPTAEMQRALGD
CHHHHCCHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHCCEEEECCHHHHHHHHCC
KVSARKVAMAAGVTTVPGTEDPIEHEEEALIFAKNYGYPIIIKAAAGGGGRGMRVARTKK
CHHHHHHHHHCCCEECCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCHHHHHH
ELLEGLVAARSEAKAAFGNPAVFLERYIENPKHIEVQVLGDMHGNLVHFFERDCSIQRRH
HHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHCCHHHHHH
QKVVEFAPALCLSQETREAICAAALKIAGQVGYRNAGTVEFLLDQEGNFFFIEMNPRIQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEECCCEEE
EHTVTEMITGRNLVQAQILVAEGKKLSDAPINIPNQEAIAMRGYAIQCRITTEDPNNNFA
HHHHHHHHCCCCHHEEEEEEECCCCCCCCCCCCCCCCEEEECCEEEEEEEEECCCCCCCC
PDFGTITTYRSSAGFGVRLDAGNAFTGSVITPHYDSLLVKVTSWGLTFDEAAHIMNRSLQ
CCCCCEEEEECCCCCEEEEECCCCEECCCCCCCHHHEEEEEEECCCCHHHHHHHHHHHHH
EFRVRGVKTNIGFLENVITHRVFLDGKCDTSFIEKHSELLQIIEKKDRATKVLSFLGDVI
HHHHCCCCCCHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
VNGSPGITKPLKSAELMEAHVPEVDLTQPRPAGSRDLLMKLGAEGLSKWILEQKKLLITD
ECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHCCCEEEEE
TTMRDAHQSNLATRVRTYDLLKIAEPTSYLGAGLFSIECWGGATFDVSMRFLKEDPWQRL
CHHHHHHHHHHHHHHHHHHHHEECCCHHHHCCCEEEEEECCCCEEHHHHHHHHCCHHHHH
HKLSEAIPNVLFQMLLRGSNAVGYTNYPDNVVQRFVEEAASSGIDIFRVFDSLNWTRGMA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEHHHHCCCCHHHHH
VAMEAVRKSGKICEAAICYTGDITDPTRDKYPLEYYVNMAKELEQMGAHILAIKDMAGLL
HHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHH
KPFAAYKLVKALKENIGIPVHLHTHDTSSNGSATLLMACQAGVDIVDAALSSLSGLTAQP
HHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCC
NLNALVAALKGTEWDTRLDEDGLQKLANYWETVRDYYAPFESGLKNGTAEVYHHEIPGGQ
CHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
YSNYKPQVAGLGLLDRWEECKEMYHKVNLLFGDIVKVTPSSKVVGDMAMFLVKNNLDVQD
CCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHCCCCHHH
VFTQGDELAFPESVIGMFKGMLGQPYQGWPRELQKIILKGDEPITCRPGELLEPANFDEE
HHCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCCCHH
RDKVEEKVGHAVDDKALMSYIMYPHVYPEFHKHRHEYSDTSVIPTPIFFYGLEPGQETSI
HHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCEE
EIEAGKTLIIKLNAIGKVHPDGTRHIFFELNGNARSVVVRDQSVQTDESVREKADKGNAK
EEECCCEEEEEEECCCCCCCCCCEEEEEEECCCEEEEEEECCCCCCHHHHHHHHHCCCCC
HVGAPMPGKVLKLNVKVGDEVKAGDVLMVTEAMKMETNIKAKEDGIVAEVKFKEGDKVEK
CCCCCCCCCEEEEEEEECCCCCCCCEEEEEHHHHHHCCCCCCCCCEEEEEEECCCCCCCC
EDLLIVMG
CCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]