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The map label for this gene is yciR [C]

Identifier: 78222002

GI number: 78222002

Start: 861917

End: 864127

Strand: Direct

Name: yciR [C]

Synonym: Gmet_0782

Alternate gene names: 78222002

Gene position: 861917-864127 (Clockwise)

Preceding gene: 78222001

Following gene: 78222010

Centisome position: 21.56

GC content: 59.57

Gene sequence:

>2211_bases
GTGACAACACTCTACAGATCCATAGCCCGTCTCACCACTCTCTTTGCGGGGGCCATAACCATTACCGTGGCGGTTCTGGT
CCCTGCCGGCTATTTTCTGGTTTCCTACCAGTATCTGCTTGGCAGCCTCGATACCCAGGCCGAAGTCAACTCTCGGGCCG
TCACCCGCCTGGTAACGGCAAATCCCGAGATGTGGCGGTATGAAGAGGTCCGGCTCATGGAGCTGTTGGAGCGCCGCAGC
CGGCGGGATATCCCCGAGGTGCGGCGGGTTCTGGATCTCCAGGGGAAAACCATCGTGGCGAGTGCGGACCATTTGCGTCC
GCCGGTGGTGTCGCGGCGCTATGCCATCTATGACGCCGGTCACGCGGTAGCTCAGCTGGAAATTTCCCGTTCCCTCGGCC
CCCTGCTGCTCGAAACGGCCCTGGTGGCCGCCTGCGCGCTGCTGGTGGGAGGGCTCGGTTTCGTCATGCTCCGCACAATC
CCCTTGCGGGCCGTCAACCAGGCTCACCAGTCCCTGGCGGAGAGCGAAGCGAAATATCGTTCCCTCTACGATTCGATGAA
GGAGGGGATGGCGCTGCACCGGATCATCTCCGACATGGAGGGCAATTCCGTCGGCTTCGAGGTGGTCGACGTAAACCCTT
CGTTCGCGTCGATCCTCGGCATGGAGAAATCGGCGATTATCGGCATGGGGGGCGAAGAGTTTTTCAGCGGTGCGCTTATG
GCCCGTTTTGCCGAGATAGTTCGCGGAGCAGAGAGCGGCGAGGCGCTGATGTTCGAATTGCCCCTGCCGGAGAAAAACCT
CTTTTTTGATGTGTCGGTGTTTTATCCGGATAGCGGTCTGTTTGCGACCTTGTTCGAGGATACCACGGAGCGGAAGAAGT
CGGACGAACAGATCCAGAGACTTGCCTACTACGACACCCTGACGGCGTTACCGAATCGAACCCTCTTCCTCGACCGGTTG
GAACAGGCCCTTGCCGGGGCCATCCGCGATAACGGCAAGTTTGCCCTTTTCTTCATCGATCTCGACGGCTTCAAGGTCAT
CAATGACAACCTGGGACACGCCCAGGGGGACCTGCTCCTCACCATGGTTTCGCAACGGCTGAGGGAAGGCATCCGCCGCA
AGGACACCCTTGCCCGGCTGGGGGGCGATGAGTTCATGGTGCTGATTTCCTACGCTGGCGAAGAACGCAATGCCGCACAC
CTCGCCCAGCACCTTCTGGAGAGGATTTCGCCTCCCTACGAGATCGGCAGCCGTGTCGTTTACACTTCCGCAAGCATCGG
TATTTCCATCTTTCCCGATGACGGGCGCGACGCAGAGACGCTCCTGCGATGCGCCGACATGGCCATGTACGCAGCCAAGG
AAGCGGGGCGCAACGGCTACCATTTCCATTCGCCGGAAATGAACCGCAAGGCCCATGAACGGATGGAACTGGAGATGAGT
CTCCGGCAGGCCCTGGAGCGGGATGAGTTTTTCCTGGAGTTCCAGCCCATCATCAATGTTGGCGGAGACTGCCTGGTGGG
GGCCGAAGCCCTTGTCCGCTGGCAGCATCCTGCACAGGGGAGGGTCATGCCGGGAACCTTTATCCCCCTTGCGGAAAGCT
CGGGCCTGATCATTCCCCTGGGCGAGTGGGTGTTGCGGAAAGCCTGCGAGAAGATGAAGGAGTGGCGCGATGCCGGACTC
CCGCCCGTCAAGCTGTCGGTCAACATCTCGGGGCGGCAGTTTGAGCAGCGCAACTTCACTGCGTTGGTCGATGAAGTTCT
GAAGGAAACCGGCGTCGATGCCCGCGCGCTTCAGTTCGAGCTTACGGAAACCAGCCTCATGAAAGATGCCGGAGCCACGG
TGAGCGCCCTCTACAAACTCAAGGAACTGGATCTGAGGATCGTGGTCGACGACTTCGGTACGGGGTATTCTTCCCTGGCG
TATCTCAAGAACTTTCCCATCGATCACATCAAGATCGACCGCTCGTTCGTCATGGATATCTGCGACGATCCCGACGACCG
GTCCATCGTGGAAGCCATTGTCGCCATGGCAAACAAACTCAACCTCGATGTTGTGGCGGAAGGTGTTGAAACCCGCGAAC
AGCGGGACTTGCTTCTGGATCTCGGCTGCCACGAGATGCAGGGGTTCCTCTTCCACCGCCCGCTGCCCGAAGAAAAGTTC
GTTGAACTGCTGCGGGACGTGAGGCTTTGCACTCTTCCTGCGGCGCTTTGA

Upstream 100 bases:

>100_bases
CGCCACCCTCAAATTCATCGATTTCATCTACTCGCCTCAGGGCCGGGCCATCGCCGGTAAGGCAGGGGTTCTCGTTCCCG
TGGGGCGGTAAAAAGGGCCT

Downstream 100 bases:

>100_bases
TTCTTGCGCTCTTGGGCGGCATTACGGGACGCTGTCGGCCCAGAAGAAAGGCGGGCCGGTAAACTGGCCGGCAGCGTCCC
CGGAATGTTCTCCTGTTAAG

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 736; Mature: 735

Protein sequence:

>736_residues
MTTLYRSIARLTTLFAGAITITVAVLVPAGYFLVSYQYLLGSLDTQAEVNSRAVTRLVTANPEMWRYEEVRLMELLERRS
RRDIPEVRRVLDLQGKTIVASADHLRPPVVSRRYAIYDAGHAVAQLEISRSLGPLLLETALVAACALLVGGLGFVMLRTI
PLRAVNQAHQSLAESEAKYRSLYDSMKEGMALHRIISDMEGNSVGFEVVDVNPSFASILGMEKSAIIGMGGEEFFSGALM
ARFAEIVRGAESGEALMFELPLPEKNLFFDVSVFYPDSGLFATLFEDTTERKKSDEQIQRLAYYDTLTALPNRTLFLDRL
EQALAGAIRDNGKFALFFIDLDGFKVINDNLGHAQGDLLLTMVSQRLREGIRRKDTLARLGGDEFMVLISYAGEERNAAH
LAQHLLERISPPYEIGSRVVYTSASIGISIFPDDGRDAETLLRCADMAMYAAKEAGRNGYHFHSPEMNRKAHERMELEMS
LRQALERDEFFLEFQPIINVGGDCLVGAEALVRWQHPAQGRVMPGTFIPLAESSGLIIPLGEWVLRKACEKMKEWRDAGL
PPVKLSVNISGRQFEQRNFTALVDEVLKETGVDARALQFELTETSLMKDAGATVSALYKLKELDLRIVVDDFGTGYSSLA
YLKNFPIDHIKIDRSFVMDICDDPDDRSIVEAIVAMANKLNLDVVAEGVETREQRDLLLDLGCHEMQGFLFHRPLPEEKF
VELLRDVRLCTLPAAL

Sequences:

>Translated_736_residues
MTTLYRSIARLTTLFAGAITITVAVLVPAGYFLVSYQYLLGSLDTQAEVNSRAVTRLVTANPEMWRYEEVRLMELLERRS
RRDIPEVRRVLDLQGKTIVASADHLRPPVVSRRYAIYDAGHAVAQLEISRSLGPLLLETALVAACALLVGGLGFVMLRTI
PLRAVNQAHQSLAESEAKYRSLYDSMKEGMALHRIISDMEGNSVGFEVVDVNPSFASILGMEKSAIIGMGGEEFFSGALM
ARFAEIVRGAESGEALMFELPLPEKNLFFDVSVFYPDSGLFATLFEDTTERKKSDEQIQRLAYYDTLTALPNRTLFLDRL
EQALAGAIRDNGKFALFFIDLDGFKVINDNLGHAQGDLLLTMVSQRLREGIRRKDTLARLGGDEFMVLISYAGEERNAAH
LAQHLLERISPPYEIGSRVVYTSASIGISIFPDDGRDAETLLRCADMAMYAAKEAGRNGYHFHSPEMNRKAHERMELEMS
LRQALERDEFFLEFQPIINVGGDCLVGAEALVRWQHPAQGRVMPGTFIPLAESSGLIIPLGEWVLRKACEKMKEWRDAGL
PPVKLSVNISGRQFEQRNFTALVDEVLKETGVDARALQFELTETSLMKDAGATVSALYKLKELDLRIVVDDFGTGYSSLA
YLKNFPIDHIKIDRSFVMDICDDPDDRSIVEAIVAMANKLNLDVVAEGVETREQRDLLLDLGCHEMQGFLFHRPLPEEKF
VELLRDVRLCTLPAAL
>Mature_735_residues
TTLYRSIARLTTLFAGAITITVAVLVPAGYFLVSYQYLLGSLDTQAEVNSRAVTRLVTANPEMWRYEEVRLMELLERRSR
RDIPEVRRVLDLQGKTIVASADHLRPPVVSRRYAIYDAGHAVAQLEISRSLGPLLLETALVAACALLVGGLGFVMLRTIP
LRAVNQAHQSLAESEAKYRSLYDSMKEGMALHRIISDMEGNSVGFEVVDVNPSFASILGMEKSAIIGMGGEEFFSGALMA
RFAEIVRGAESGEALMFELPLPEKNLFFDVSVFYPDSGLFATLFEDTTERKKSDEQIQRLAYYDTLTALPNRTLFLDRLE
QALAGAIRDNGKFALFFIDLDGFKVINDNLGHAQGDLLLTMVSQRLREGIRRKDTLARLGGDEFMVLISYAGEERNAAHL
AQHLLERISPPYEIGSRVVYTSASIGISIFPDDGRDAETLLRCADMAMYAAKEAGRNGYHFHSPEMNRKAHERMELEMSL
RQALERDEFFLEFQPIINVGGDCLVGAEALVRWQHPAQGRVMPGTFIPLAESSGLIIPLGEWVLRKACEKMKEWRDAGLP
PVKLSVNISGRQFEQRNFTALVDEVLKETGVDARALQFELTETSLMKDAGATVSALYKLKELDLRIVVDDFGTGYSSLAY
LKNFPIDHIKIDRSFVMDICDDPDDRSIVEAIVAMANKLNLDVVAEGVETREQRDLLLDLGCHEMQGFLFHRPLPEEKFV
ELLRDVRLCTLPAAL

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=478, Percent_Identity=40.7949790794979, Blast_Score=340, Evalue=3e-94,
Organism=Escherichia coli, GI87081921, Length=431, Percent_Identity=35.4988399071926, Blast_Score=266, Evalue=3e-72,
Organism=Escherichia coli, GI226510982, Length=416, Percent_Identity=33.8942307692308, Blast_Score=218, Evalue=1e-57,
Organism=Escherichia coli, GI1786507, Length=267, Percent_Identity=34.0823970037453, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI1788849, Length=439, Percent_Identity=30.0683371298405, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI1788502, Length=252, Percent_Identity=32.9365079365079, Blast_Score=156, Evalue=4e-39,
Organism=Escherichia coli, GI87081743, Length=241, Percent_Identity=34.4398340248963, Blast_Score=151, Evalue=2e-37,
Organism=Escherichia coli, GI87081845, Length=261, Percent_Identity=34.4827586206897, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI1790496, Length=249, Percent_Identity=32.1285140562249, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI87081980, Length=254, Percent_Identity=30.7086614173228, Blast_Score=138, Evalue=2e-33,
Organism=Escherichia coli, GI1787055, Length=391, Percent_Identity=26.0869565217391, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI87082096, Length=433, Percent_Identity=25.8660508083141, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1788381, Length=197, Percent_Identity=34.5177664974619, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI87081977, Length=325, Percent_Identity=27.0769230769231, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1786584, Length=263, Percent_Identity=28.8973384030418, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787262, Length=166, Percent_Identity=34.3373493975904, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI145693134, Length=156, Percent_Identity=35.2564102564103, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI87082007, Length=164, Percent_Identity=32.9268292682927, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081974, Length=124, Percent_Identity=35.4838709677419, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87081881, Length=179, Percent_Identity=31.2849162011173, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1788956, Length=168, Percent_Identity=34.5238095238095, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787816, Length=157, Percent_Identity=30.5732484076433, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1787802, Length=172, Percent_Identity=26.1627906976744, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788085, Length=174, Percent_Identity=29.8850574712644, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 82249; Mature: 82118

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS50883 EAL ; PS50887 GGDEF ; PS00284 SERPIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLYRSIARLTTLFAGAITITVAVLVPAGYFLVSYQYLLGSLDTQAEVNSRAVTRLVTA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCHHHHHHEEEC
NPEMWRYEEVRLMELLERRSRRDIPEVRRVLDLQGKTIVASADHLRPPVVSRRYAIYDAG
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECCHHCCCCHHHCEEEEEECC
HAVAQLEISRSLGPLLLETALVAACALLVGGLGFVMLRTIPLRAVNQAHQSLAESEAKYR
CHHEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLYDSMKEGMALHRIISDMEGNSVGFEVVDVNPSFASILGMEKSAIIGMGGEEFFSGALM
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHCCCCCEEEECCHHHHHHHHHH
ARFAEIVRGAESGEALMFELPLPEKNLFFDVSVFYPDSGLFATLFEDTTERKKSDEQIQR
HHHHHHHCCCCCCCEEEEECCCCCCCEEEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHH
LAYYDTLTALPNRTLFLDRLEQALAGAIRDNGKFALFFIDLDGFKVINDNLGHAQGDLLL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEECCCCCCCCHHHHH
TMVSQRLREGIRRKDTLARLGGDEFMVLISYAGEERNAAHLAQHLLERISPPYEIGSRVV
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHCCEEE
YTSASIGISIFPDDGRDAETLLRCADMAMYAAKEAGRNGYHFHSPEMNRKAHERMELEMS
EEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
LRQALERDEFFLEFQPIINVGGDCLVGAEALVRWQHPAQGRVMPGTFIPLAESSGLIIPL
HHHHHCCCCEEEEEEHHHCCCCCCEECHHHHHCCCCCCCCCCCCCCEEEECCCCCEEEEC
GEWVLRKACEKMKEWRDAGLPPVKLSVNISGRQFEQRNFTALVDEVLKETGVDARALQFE
HHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEE
LTETSLMKDAGATVSALYKLKELDLRIVVDDFGTGYSSLAYLKNFPIDHIKIDRSFVMDI
EHHHHHHHHCCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHCCCCCEEEECHHHHHHH
CDDPDDRSIVEAIVAMANKLNLDVVAEGVETREQRDLLLDLGCHEMQGFLFHRPLPEEKF
CCCCCCHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHCCHHHHCCHHHCCCCCHHHH
VELLRDVRLCTLPAAL
HHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TTLYRSIARLTTLFAGAITITVAVLVPAGYFLVSYQYLLGSLDTQAEVNSRAVTRLVTA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCHHHHHHEEEC
NPEMWRYEEVRLMELLERRSRRDIPEVRRVLDLQGKTIVASADHLRPPVVSRRYAIYDAG
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECCHHCCCCHHHCEEEEEECC
HAVAQLEISRSLGPLLLETALVAACALLVGGLGFVMLRTIPLRAVNQAHQSLAESEAKYR
CHHEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLYDSMKEGMALHRIISDMEGNSVGFEVVDVNPSFASILGMEKSAIIGMGGEEFFSGALM
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHCCCCCEEEECCHHHHHHHHHH
ARFAEIVRGAESGEALMFELPLPEKNLFFDVSVFYPDSGLFATLFEDTTERKKSDEQIQR
HHHHHHHCCCCCCCEEEEECCCCCCCEEEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHH
LAYYDTLTALPNRTLFLDRLEQALAGAIRDNGKFALFFIDLDGFKVINDNLGHAQGDLLL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEECCCCCCCCHHHHH
TMVSQRLREGIRRKDTLARLGGDEFMVLISYAGEERNAAHLAQHLLERISPPYEIGSRVV
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHCCEEE
YTSASIGISIFPDDGRDAETLLRCADMAMYAAKEAGRNGYHFHSPEMNRKAHERMELEMS
EEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
LRQALERDEFFLEFQPIINVGGDCLVGAEALVRWQHPAQGRVMPGTFIPLAESSGLIIPL
HHHHHCCCCEEEEEEHHHCCCCCCEECHHHHHCCCCCCCCCCCCCCEEEECCCCCEEEEC
GEWVLRKACEKMKEWRDAGLPPVKLSVNISGRQFEQRNFTALVDEVLKETGVDARALQFE
HHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEE
LTETSLMKDAGATVSALYKLKELDLRIVVDDFGTGYSSLAYLKNFPIDHIKIDRSFVMDI
EHHHHHHHHCCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHCCCCCEEEECHHHHHHH
CDDPDDRSIVEAIVAMANKLNLDVVAEGVETREQRDLLLDLGCHEMQGFLFHRPLPEEKF
CCCCCCHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHCCHHHHCCHHHCCCCCHHHH
VELLRDVRLCTLPAAL
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]