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The map label for this gene is ntrY [H]

Identifier: 78221997

GI number: 78221997

Start: 853853

End: 856099

Strand: Reverse

Name: ntrY [H]

Synonym: Gmet_0777

Alternate gene names: 78221997

Gene position: 856099-853853 (Counterclockwise)

Preceding gene: 78221998

Following gene: 78221996

Centisome position: 21.42

GC content: 62.08

Gene sequence:

>2247_bases
ATGGTTGAAAACCATCACCAGCAGCCACCCATCATTTCCCCTCCGGAACAGGAGCGGAAGAAGCGGCGGCGGGAAGCGAT
TATCATCGCCATCTCCGTCCTGCTGATCCTCGTGCTGACCCGGGCCGAGATCCACCTCTCCCGCATCAGCTCCGAAGTCC
CCATGGGGAGCAACATCCTCATCTTCGGCATCATCAACATCATCATTCTCCTCATCATTCTCCTCATCTACCTGGTTTTC
CGCAATGTGGCCAAGCTCCTCATGGAGCGACGAAGCAAGGCCATTGGCGCCAATCTCCAGACCAAGCTCGTCATCGCCTT
CATGGGACTGTCGCTGGTACCGACCATGCTCCTCTTCGTGGTGTCGGCCTCCTACGTCAACATGAGTATCCGCAACTGGT
TCAACACCCAGGTCGAGAGCTCCCTGTCCGAGTCCCTGGAGGTGGCCCAGACCTACTACAAAAACTCGGCCGCCAACGCC
CTCTATTACGGCCGGCAGATCAGTTCCATCATCCGGGACGAGCGGCTCCTGAACGAGGAAAACCTTCCCCGGCTCCGGGA
GCTGGTCCGCCGGAAGCAGCAGGAGTACAACCTCGGCATCGTGGAGGTCTACTCCTCCCAGAACGAAGAGCTGGTCCGGT
CGTCGAACCCCGGCGTCCCCCAGGGGGAATTCACGAACCCCTCCTCCGAGGACATCAAGATGGGGCTCAACGGCAAGGAA
CTGAGTCGCGTCAACACCGTGGGGAAAGCCGACCTGATCCGCGGCATCATGCCCATCTACTCCACCTACCGGGCCGACGA
GGTGGTGGGGGTGGTGGTGGTGAACTACGTCGTCCCCTACTCCCTCGTGGAGAAGATGCGGGAGATCACCAGCTCCTACG
AGGAGTTCCGCCAGCTCAAGATCCTCAAGAACCCCATCCGCTCGGGGTACATCCTGACCCTCTTCCTTGTCACCATGGTG
ATCGTCTTCCTGGCGGTCTGGTTCGGCATCTACCTGGCCAACAGCCTCACGACCCCCATCAAGGAGCTGGCCGAGGCGAC
CCGCCAGGTGGCCGAGGGAAACCTGGACGTGCAACTGGGGCAGCGCTCGAGCGACGAGTTCGGGATGCTCGTGGCCGCCT
TCAACAAGATGACCCTGGACCTGCGGAGCCACCAGCAGGCCCTGCGCCAGACCAACATCGAGCTCGTCCGGAGCAACCAG
GAGCTGGACGAGCGGCGCCGCAACATGGAGATCGTGCTGCGCAACGTGGCCGCCGGCGTCATCTCCGTGGACAGTCATGG
TGTGATCACCACCATCAACAAATCGGCGGAGGAGCTCCTGCAGGTCGCCGCCCGCGACGTGGTGGGGAAGAACTTCCGGG
AGGTTCTCAAGCACGAGCAGATCGACACCCTCAAGGGTATCCTGCGCGACATGGTGATGGCGAAGCAGGACACCATCAGC
CGTCAGGTGACGGTCCCGATCCGCGACTCCAGGGCGACACTCCTCTTCAACCTGACCATGCTGCGGGACGAAAGCGGCGA
GTTCCTGGGAACGGTGGTGGTCTTCGACGACCTGACCCAGCTCATCAAGGCCCAGCGGATGGCGGCCTGGCGGGAAGTGG
CCCGGCGCATCGCCCACGAGATCAAGAACCCCCTGACGCCGATCCAGCTTTCCGCTCAGCGGCTGAGAAAGCGCTATCTC
CCCCGCTTCGGCGACGAAGACACCGTCTTTGACGAATGCACCGCCATGATCGTCAAATCGGTGGATGAGCTGAAAAACCT
CGTGAACGAATTCTCCAGCTTTGCCCGGATGCCGGCCGCCAACCCGGCCCCCAACGACCTGAACGGGATCATCCGCGAGG
CCCTCACCCTCTTCAGCCAGGGGCACAGGGCCATCTCGTTCGGCTTCCGGGAAGACCGCCGGCTCCCCCATCTGCAGCTC
GACCGGGATCAGATCAAGCGGGTCTTCATCAACCTCCTGGACAACGCCGTGGCGGCCGTGGCCGAAGAGGGGGAGATCGA
AATCGAAAGCCGCTTCGATCCCGTCCTGAAGATGGCGGTGATCACCGTGGCCGACACGGGACACGGCATCGCCCCCGAGG
ACAAGCCCCGCCTCTTCGAGCCGTATTTCTCCACCAAGAAGTCCGGGACCGGCCTGGGGCTTGCCATCGTCAGCACCATC
ATCGCCGACCACAACGGCTTCATCCGCGTGCGGGACAATCTTCCCCACGGGACGAAATTCATCATCGAGCTGCCGGTAAC
GGCGTAA

Upstream 100 bases:

>100_bases
TTTCGAGACCGCCCTTCGGCAAATCGCTCCCTTGCATTAACGCTCCCGTTTGTATAAAGTGACCCTGTTGCATTTTTGCC
ACACCAAGGATTCCCCATCA

Downstream 100 bases:

>100_bases
TAATCCAAATAACACGGAGAAACGGAGGACACGGAGCAAATCAAAAACCGGCGTTCAGAATCATTTCTGGTAGCCTCTCT
GTTTTTTTCTCTTGGTTTCT

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 748; Mature: 748

Protein sequence:

>748_residues
MVENHHQQPPIISPPEQERKKRRREAIIIAISVLLILVLTRAEIHLSRISSEVPMGSNILIFGIINIIILLIILLIYLVF
RNVAKLLMERRSKAIGANLQTKLVIAFMGLSLVPTMLLFVVSASYVNMSIRNWFNTQVESSLSESLEVAQTYYKNSAANA
LYYGRQISSIIRDERLLNEENLPRLRELVRRKQQEYNLGIVEVYSSQNEELVRSSNPGVPQGEFTNPSSEDIKMGLNGKE
LSRVNTVGKADLIRGIMPIYSTYRADEVVGVVVVNYVVPYSLVEKMREITSSYEEFRQLKILKNPIRSGYILTLFLVTMV
IVFLAVWFGIYLANSLTTPIKELAEATRQVAEGNLDVQLGQRSSDEFGMLVAAFNKMTLDLRSHQQALRQTNIELVRSNQ
ELDERRRNMEIVLRNVAAGVISVDSHGVITTINKSAEELLQVAARDVVGKNFREVLKHEQIDTLKGILRDMVMAKQDTIS
RQVTVPIRDSRATLLFNLTMLRDESGEFLGTVVVFDDLTQLIKAQRMAAWREVARRIAHEIKNPLTPIQLSAQRLRKRYL
PRFGDEDTVFDECTAMIVKSVDELKNLVNEFSSFARMPAANPAPNDLNGIIREALTLFSQGHRAISFGFREDRRLPHLQL
DRDQIKRVFINLLDNAVAAVAEEGEIEIESRFDPVLKMAVITVADTGHGIAPEDKPRLFEPYFSTKKSGTGLGLAIVSTI
IADHNGFIRVRDNLPHGTKFIIELPVTA

Sequences:

>Translated_748_residues
MVENHHQQPPIISPPEQERKKRRREAIIIAISVLLILVLTRAEIHLSRISSEVPMGSNILIFGIINIIILLIILLIYLVF
RNVAKLLMERRSKAIGANLQTKLVIAFMGLSLVPTMLLFVVSASYVNMSIRNWFNTQVESSLSESLEVAQTYYKNSAANA
LYYGRQISSIIRDERLLNEENLPRLRELVRRKQQEYNLGIVEVYSSQNEELVRSSNPGVPQGEFTNPSSEDIKMGLNGKE
LSRVNTVGKADLIRGIMPIYSTYRADEVVGVVVVNYVVPYSLVEKMREITSSYEEFRQLKILKNPIRSGYILTLFLVTMV
IVFLAVWFGIYLANSLTTPIKELAEATRQVAEGNLDVQLGQRSSDEFGMLVAAFNKMTLDLRSHQQALRQTNIELVRSNQ
ELDERRRNMEIVLRNVAAGVISVDSHGVITTINKSAEELLQVAARDVVGKNFREVLKHEQIDTLKGILRDMVMAKQDTIS
RQVTVPIRDSRATLLFNLTMLRDESGEFLGTVVVFDDLTQLIKAQRMAAWREVARRIAHEIKNPLTPIQLSAQRLRKRYL
PRFGDEDTVFDECTAMIVKSVDELKNLVNEFSSFARMPAANPAPNDLNGIIREALTLFSQGHRAISFGFREDRRLPHLQL
DRDQIKRVFINLLDNAVAAVAEEGEIEIESRFDPVLKMAVITVADTGHGIAPEDKPRLFEPYFSTKKSGTGLGLAIVSTI
IADHNGFIRVRDNLPHGTKFIIELPVTA
>Mature_748_residues
MVENHHQQPPIISPPEQERKKRRREAIIIAISVLLILVLTRAEIHLSRISSEVPMGSNILIFGIINIIILLIILLIYLVF
RNVAKLLMERRSKAIGANLQTKLVIAFMGLSLVPTMLLFVVSASYVNMSIRNWFNTQVESSLSESLEVAQTYYKNSAANA
LYYGRQISSIIRDERLLNEENLPRLRELVRRKQQEYNLGIVEVYSSQNEELVRSSNPGVPQGEFTNPSSEDIKMGLNGKE
LSRVNTVGKADLIRGIMPIYSTYRADEVVGVVVVNYVVPYSLVEKMREITSSYEEFRQLKILKNPIRSGYILTLFLVTMV
IVFLAVWFGIYLANSLTTPIKELAEATRQVAEGNLDVQLGQRSSDEFGMLVAAFNKMTLDLRSHQQALRQTNIELVRSNQ
ELDERRRNMEIVLRNVAAGVISVDSHGVITTINKSAEELLQVAARDVVGKNFREVLKHEQIDTLKGILRDMVMAKQDTIS
RQVTVPIRDSRATLLFNLTMLRDESGEFLGTVVVFDDLTQLIKAQRMAAWREVARRIAHEIKNPLTPIQLSAQRLRKRYL
PRFGDEDTVFDECTAMIVKSVDELKNLVNEFSSFARMPAANPAPNDLNGIIREALTLFSQGHRAISFGFREDRRLPHLQL
DRDQIKRVFINLLDNAVAAVAEEGEIEIESRFDPVLKMAVITVADTGHGIAPEDKPRLFEPYFSTKKSGTGLGLAIVSTI
IADHNGFIRVRDNLPHGTKFIIELPVTA

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=356, Percent_Identity=29.4943820224719, Blast_Score=163, Evalue=3e-41,
Organism=Escherichia coli, GI1790436, Length=230, Percent_Identity=33.0434782608696, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1790300, Length=350, Percent_Identity=30.5714285714286, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI1789808, Length=216, Percent_Identity=30.0925925925926, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1786600, Length=248, Percent_Identity=27.8225806451613, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790346, Length=253, Percent_Identity=26.8774703557312, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1788393, Length=245, Percent_Identity=26.530612244898, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 84497; Mature: 84497

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVENHHQQPPIISPPEQERKKRRREAIIIAISVLLILVLTRAEIHLSRISSEVPMGSNIL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
IFGIINIIILLIILLIYLVFRNVAKLLMERRSKAIGANLQTKLVIAFMGLSLVPTMLLFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VSASYVNMSIRNWFNTQVESSLSESLEVAQTYYKNSAANALYYGRQISSIIRDERLLNEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
NLPRLRELVRRKQQEYNLGIVEVYSSQNEELVRSSNPGVPQGEFTNPSSEDIKMGLNGKE
CCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHCCCCCCCCCCCCCCCCCCEEECCCCHH
LSRVNTVGKADLIRGIMPIYSTYRADEVVGVVVVNYVVPYSLVEKMREITSSYEEFRQLK
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILKNPIRSGYILTLFLVTMVIVFLAVWFGIYLANSLTTPIKELAEATRQVAEGNLDVQLG
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEC
QRSSDEFGMLVAAFNKMTLDLRSHQQALRQTNIELVRSNQELDERRRNMEIVLRNVAAGV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHCE
ISVDSHGVITTINKSAEELLQVAARDVVGKNFREVLKHEQIDTLKGILRDMVMAKQDTIS
EEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RQVTVPIRDSRATLLFNLTMLRDESGEFLGTVVVFDDLTQLIKAQRMAAWREVARRIAHE
CEEEEEECCCCEEEEEEEHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKNPLTPIQLSAQRLRKRYLPRFGDEDTVFDECTAMIVKSVDELKNLVNEFSSFARMPAA
HHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NPAPNDLNGIIREALTLFSQGHRAISFGFREDRRLPHLQLDRDQIKRVFINLLDNAVAAV
CCCCCHHHHHHHHHHHHHHCCCCEEECCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AEEGEIEIESRFDPVLKMAVITVADTGHGIAPEDKPRLFEPYFSTKKSGTGLGLAIVSTI
HCCCCEEEHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHH
IADHNGFIRVRDNLPHGTKFIIELPVTA
HHCCCCEEEEECCCCCCCEEEEEECCCC
>Mature Secondary Structure
MVENHHQQPPIISPPEQERKKRRREAIIIAISVLLILVLTRAEIHLSRISSEVPMGSNIL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
IFGIINIIILLIILLIYLVFRNVAKLLMERRSKAIGANLQTKLVIAFMGLSLVPTMLLFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VSASYVNMSIRNWFNTQVESSLSESLEVAQTYYKNSAANALYYGRQISSIIRDERLLNEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
NLPRLRELVRRKQQEYNLGIVEVYSSQNEELVRSSNPGVPQGEFTNPSSEDIKMGLNGKE
CCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHCCCCCCCCCCCCCCCCCCEEECCCCHH
LSRVNTVGKADLIRGIMPIYSTYRADEVVGVVVVNYVVPYSLVEKMREITSSYEEFRQLK
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILKNPIRSGYILTLFLVTMVIVFLAVWFGIYLANSLTTPIKELAEATRQVAEGNLDVQLG
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEC
QRSSDEFGMLVAAFNKMTLDLRSHQQALRQTNIELVRSNQELDERRRNMEIVLRNVAAGV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHCE
ISVDSHGVITTINKSAEELLQVAARDVVGKNFREVLKHEQIDTLKGILRDMVMAKQDTIS
EEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RQVTVPIRDSRATLLFNLTMLRDESGEFLGTVVVFDDLTQLIKAQRMAAWREVARRIAHE
CEEEEEECCCCEEEEEEEHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKNPLTPIQLSAQRLRKRYLPRFGDEDTVFDECTAMIVKSVDELKNLVNEFSSFARMPAA
HHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NPAPNDLNGIIREALTLFSQGHRAISFGFREDRRLPHLQLDRDQIKRVFINLLDNAVAAV
CCCCCHHHHHHHHHHHHHHCCCCEEECCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AEEGEIEIESRFDPVLKMAVITVADTGHGIAPEDKPRLFEPYFSTKKSGTGLGLAIVSTI
HCCCCEEEHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHH
IADHNGFIRVRDNLPHGTKFIIELPVTA
HHCCCCEEEEECCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]