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The map label for this gene is dnaA [H]

Identifier: 78221967

GI number: 78221967

Start: 820657

End: 821388

Strand: Direct

Name: dnaA [H]

Synonym: Gmet_0747

Alternate gene names: 78221967

Gene position: 820657-821388 (Clockwise)

Preceding gene: 78221966

Following gene: 78221968

Centisome position: 20.53

GC content: 62.7

Gene sequence:

>732_bases
ATGCAACTTGTCTTCGACTTTCCCGTCAATCCCAAGTATTCCCTCGACAATTTCGTCATCTGCTCCGGCAACGAAACCGC
CTACCGCTTTGTCCGGCGGCTCACGGACGACGAGGGGGCGGAGAACCTCCTCTACCTCCACGGCCCCTCCGGGTCCGGAA
AGACCCACCTTCTCATGGCGATTGGAGCACACTTCAGCGCACGGGCGGGACTCTCGTCGGTTCCCTGCATCTCCTTCAAG
GACGTGGACGAGGTGTATGGCGGAGAATACCCGGCCGAGGCGGTGTCGAAACTGGCCGAGCGGTTTCGCAACGCTCCGGC
CCTCCTCGTGGACGACCTCCACCTCATCCCCGACCAGCAGGCGGTGCGGGTCGAGCTCTGGCAACTCTTCAACGACTTTT
ACCAGGCCGGCCGCCCCATCGCTATCACCGGCCTGTACCCCCCGAAAGAACTTCCCACCATTGATGACCACCTCATCTCC
CGCCTCCTCTGGGGGCTCGTGGCCCGGGTCGACATCTCCGACGACGACTCCCGCCGTCTCATCATGAAAAAACTCGCTGA
TGACCGCCAGATTGTCCTCCCCGCCGACGTCATCGATTACCTCCTCCTCCACGTCCGCCGCGACGTTCCCTCCCTCATTG
AGGCACTGGACGCTATCAGCCGGTATGCCCTGGCCGCCAAGCGGAAGGTTTCCGTGCGGCTGGCCCGGGAGGCGCTGGCT
TTTCACTCCTAA

Upstream 100 bases:

>100_bases
CCGCACCCCCCGCGGACGGGTGGCGACCAGGGCGGCCTACGAGCACTTCGGCCGCATCGCTCCGCCGTCATCGTCCCAGG
GGAATCTTTTCTAACGTCCC

Downstream 100 bases:

>100_bases
AATTTTTCATCGTTGTTGAAGTTTACTTGTTGGATTGTCGGATTACTTTACATGCGTGTTGTCGCGTTTTGTTGTCGTAA
CTGTTCGAAATGACTTGCTA

Product: regulatory inactivation of DnaA Hda protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MQLVFDFPVNPKYSLDNFVICSGNETAYRFVRRLTDDEGAENLLYLHGPSGSGKTHLLMAIGAHFSARAGLSSVPCISFK
DVDEVYGGEYPAEAVSKLAERFRNAPALLVDDLHLIPDQQAVRVELWQLFNDFYQAGRPIAITGLYPPKELPTIDDHLIS
RLLWGLVARVDISDDDSRRLIMKKLADDRQIVLPADVIDYLLLHVRRDVPSLIEALDAISRYALAAKRKVSVRLAREALA
FHS

Sequences:

>Translated_243_residues
MQLVFDFPVNPKYSLDNFVICSGNETAYRFVRRLTDDEGAENLLYLHGPSGSGKTHLLMAIGAHFSARAGLSSVPCISFK
DVDEVYGGEYPAEAVSKLAERFRNAPALLVDDLHLIPDQQAVRVELWQLFNDFYQAGRPIAITGLYPPKELPTIDDHLIS
RLLWGLVARVDISDDDSRRLIMKKLADDRQIVLPADVIDYLLLHVRRDVPSLIEALDAISRYALAAKRKVSVRLAREALA
FHS
>Mature_243_residues
MQLVFDFPVNPKYSLDNFVICSGNETAYRFVRRLTDDEGAENLLYLHGPSGSGKTHLLMAIGAHFSARAGLSSVPCISFK
DVDEVYGGEYPAEAVSKLAERFRNAPALLVDDLHLIPDQQAVRVELWQLFNDFYQAGRPIAITGLYPPKELPTIDDHLIS
RLLWGLVARVDISDDDSRRLIMKKLADDRQIVLPADVIDYLLLHVRRDVPSLIEALDAISRYALAAKRKVSVRLAREALA
FHS

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family [H]

Homologues:

Organism=Escherichia coli, GI2367267, Length=232, Percent_Identity=30.6034482758621, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI226510964, Length=199, Percent_Identity=24.6231155778894, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921 [H]

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C [H]

EC number: NA

Molecular weight: Translated: 27243; Mature: 27243

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLVFDFPVNPKYSLDNFVICSGNETAYRFVRRLTDDEGAENLLYLHGPSGSGKTHLLMA
CCEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEEEEE
IGAHFSARAGLSSVPCISFKDVDEVYGGEYPAEAVSKLAERFRNAPALLVDDLHLIPDQQ
ECCCHHHHCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHCCCCEEEECCHHHCCCCH
AVRVELWQLFNDFYQAGRPIAITGLYPPKELPTIDDHLISRLLWGLVARVDISDDDSRRL
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHEECCCCCCHHHH
IMKKLADDRQIVLPADVIDYLLLHVRRDVPSLIEALDAISRYALAAKRKVSVRLAREALA
HHHHHCCCCEEEECHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FHS
CCC
>Mature Secondary Structure
MQLVFDFPVNPKYSLDNFVICSGNETAYRFVRRLTDDEGAENLLYLHGPSGSGKTHLLMA
CCEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEEEEE
IGAHFSARAGLSSVPCISFKDVDEVYGGEYPAEAVSKLAERFRNAPALLVDDLHLIPDQQ
ECCCHHHHCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHCCCCEEEECCHHHCCCCH
AVRVELWQLFNDFYQAGRPIAITGLYPPKELPTIDDHLISRLLWGLVARVDISDDDSRRL
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHEECCCCCCHHHH
IMKKLADDRQIVLPADVIDYLLLHVRRDVPSLIEALDAISRYALAAKRKVSVRLAREALA
HHHHHCCCCEEEECHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FHS
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA