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The map label for this gene is ruvB

Identifier: 78221966

GI number: 78221966

Start: 819634

End: 820650

Strand: Direct

Name: ruvB

Synonym: Gmet_0746

Alternate gene names: 78221966

Gene position: 819634-820650 (Clockwise)

Preceding gene: 78221965

Following gene: 78221967

Centisome position: 20.5

GC content: 64.41

Gene sequence:

>1017_bases
ATGACCCGACTCGTTACCCCCGACATAACCGAAGACGACCTGATCGAATCGTCCCTGCGCCCCCGGGCACTGGACGACTA
CATCGGCCAGGAGAAGGCCAAGGGAAACCTGCGGGTCTTCATCGATGCGGCGCGGAAGCGGGGCGAGGCCCTGGACCACG
TCCTCCTCTATGGCCCGCCGGGGCTGGGAAAGACGACGCTGGCCAACATCATCGCCTGCGAAATGGGAGTGAACATCAAG
TCCACCTCCGGCCCGGTCATTGAGCGCCCCGGCGACCTGGCGGCGATCCTCACCAACCTGGAGCCCCACGACGTCCTTTT
CATCGATGAGATTCACCGTCTCTCCCATGTGGTGGAGGAGATCCTCTATCCGGCCATGGAGGACTACCAGCTCGACATCA
TTATCGGCCAGGGACCCAGCGCCCGGACCATCAAGCTGGACCTTCCGAAGTTCACCCTCGTGGGGGCCACCACGAGGGCC
GGCCTCCTCTCCTCGCCGCTTCGGGATCGGTTCGGGGTCATCTCCCGGCTGGAGTTCTACACCGATGATGAGCTTACCAC
CATCGTCACCCGTTCCGCCCGTATCCTGAACATCGGCATCGAACCGGAGGGTGGCCGGGAACTGGCCCGCCGAAGCCGCG
GTACCCCCCGCATCGCCAACCGTCTCCTGCGCCGGGTGCGGGACTTCGCCCAGGTCCGGGCCGATGGTGTCATCACCGCA
CCGGTGGTGGACGAATCCCTGAAACTGCTGGAGATCGACGAGAAGGGGTTCGACCATATGGACCGGACCATTATGCTCAC
CATCATCGACAAGTTCGGCGGCGGTCCCGTGGGGCTCGACACCATCGCTGCCGCCATCGGCGAGGAGCGGGACACCATCG
AGGACGTCTACGAACCGTTCCTCATCCAGCACGGCTTCATCAACCGCACCCCCCGCGGACGGGTGGCGACCAGGGCGGCC
TACGAGCACTTCGGCCGCATCGCTCCGCCGTCATCGTCCCAGGGGAATCTTTTCTAA

Upstream 100 bases:

>100_bases
GCGCCTCCACCGAAGCGGTCCTCCGGCAGGCATTGAAGATTCTGATGAAATGACAATGTAGGGGCAATTCATGAATTGCC
CTTACGGGTAGACACCCGTT

Downstream 100 bases:

>100_bases
CGTCCCATGCAACTTGTCTTCGACTTTCCCGTCAATCCCAAGTATTCCCTCGACAATTTCGTCATCTGCTCCGGCAACGA
AACCGCCTACCGCTTTGTCC

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MTRLVTPDITEDDLIESSLRPRALDDYIGQEKAKGNLRVFIDAARKRGEALDHVLLYGPPGLGKTTLANIIACEMGVNIK
STSGPVIERPGDLAAILTNLEPHDVLFIDEIHRLSHVVEEILYPAMEDYQLDIIIGQGPSARTIKLDLPKFTLVGATTRA
GLLSSPLRDRFGVISRLEFYTDDELTTIVTRSARILNIGIEPEGGRELARRSRGTPRIANRLLRRVRDFAQVRADGVITA
PVVDESLKLLEIDEKGFDHMDRTIMLTIIDKFGGGPVGLDTIAAAIGEERDTIEDVYEPFLIQHGFINRTPRGRVATRAA
YEHFGRIAPPSSSQGNLF

Sequences:

>Translated_338_residues
MTRLVTPDITEDDLIESSLRPRALDDYIGQEKAKGNLRVFIDAARKRGEALDHVLLYGPPGLGKTTLANIIACEMGVNIK
STSGPVIERPGDLAAILTNLEPHDVLFIDEIHRLSHVVEEILYPAMEDYQLDIIIGQGPSARTIKLDLPKFTLVGATTRA
GLLSSPLRDRFGVISRLEFYTDDELTTIVTRSARILNIGIEPEGGRELARRSRGTPRIANRLLRRVRDFAQVRADGVITA
PVVDESLKLLEIDEKGFDHMDRTIMLTIIDKFGGGPVGLDTIAAAIGEERDTIEDVYEPFLIQHGFINRTPRGRVATRAA
YEHFGRIAPPSSSQGNLF
>Mature_337_residues
TRLVTPDITEDDLIESSLRPRALDDYIGQEKAKGNLRVFIDAARKRGEALDHVLLYGPPGLGKTTLANIIACEMGVNIKS
TSGPVIERPGDLAAILTNLEPHDVLFIDEIHRLSHVVEEILYPAMEDYQLDIIIGQGPSARTIKLDLPKFTLVGATTRAG
LLSSPLRDRFGVISRLEFYTDDELTTIVTRSARILNIGIEPEGGRELARRSRGTPRIANRLLRRVRDFAQVRADGVITAP
VVDESLKLLEIDEKGFDHMDRTIMLTIIDKFGGGPVGLDTIAAAIGEERDTIEDVYEPFLIQHGFINRTPRGRVATRAAY
EHFGRIAPPSSSQGNLF

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=329, Percent_Identity=64.4376899696049, Blast_Score=449, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_GEOMG (Q39XN6)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_383713.1
- ProteinModelPortal:   Q39XN6
- SMR:   Q39XN6
- STRING:   Q39XN6
- GeneID:   3739884
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_0746
- NMPDR:   fig|269799.3.peg.773
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- PhylomeDB:   Q39XN6
- ProtClustDB:   PRK00080
- BioCyc:   GMET269799:GMET_0746-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 37369; Mature: 37238

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLVTPDITEDDLIESSLRPRALDDYIGQEKAKGNLRVFIDAARKRGEALDHVLLYGPP
CCCCCCCCCCHHHHHHHCCCCCHHHHHHCHHCCCCCEEEEEEEHHHCCHHHCEEEEECCC
GLGKTTLANIIACEMGVNIKSTSGPVIERPGDLAAILTNLEPHDVLFIDEIHRLSHVVEE
CCCHHHHHHHHHHHCCCEEECCCCCCEECCCCHHHHHHCCCCCCEEHHHHHHHHHHHHHH
ILYPAMEDYQLDIIIGQGPSARTIKLDLPKFTLVGATTRAGLLSSPLRDRFGVISRLEFY
HHHCCCCCEEEEEEEECCCCCEEEEEECCCEEEEECCHHHHHHHCHHHHHHHHHHHHHHC
TDDELTTIVTRSARILNIGIEPEGGRELARRSRGTPRIANRLLRRVRDFAQVRADGVITA
CCCCHHHHEECCCEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEC
PVVDESLKLLEIDEKGFDHMDRTIMLTIIDKFGGGPVGLDTIAAAIGEERDTIEDVYEPF
CCCCCCCEEEEECCCCCCHHCCEEEEEEEHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHH
LIQHGFINRTPRGRVATRAAYEHFGRIAPPSSSQGNLF
HHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TRLVTPDITEDDLIESSLRPRALDDYIGQEKAKGNLRVFIDAARKRGEALDHVLLYGPP
CCCCCCCCCHHHHHHHCCCCCHHHHHHCHHCCCCCEEEEEEEHHHCCHHHCEEEEECCC
GLGKTTLANIIACEMGVNIKSTSGPVIERPGDLAAILTNLEPHDVLFIDEIHRLSHVVEE
CCCHHHHHHHHHHHCCCEEECCCCCCEECCCCHHHHHHCCCCCCEEHHHHHHHHHHHHHH
ILYPAMEDYQLDIIIGQGPSARTIKLDLPKFTLVGATTRAGLLSSPLRDRFGVISRLEFY
HHHCCCCCEEEEEEEECCCCCEEEEEECCCEEEEECCHHHHHHHCHHHHHHHHHHHHHHC
TDDELTTIVTRSARILNIGIEPEGGRELARRSRGTPRIANRLLRRVRDFAQVRADGVITA
CCCCHHHHEECCCEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEC
PVVDESLKLLEIDEKGFDHMDRTIMLTIIDKFGGGPVGLDTIAAAIGEERDTIEDVYEPF
CCCCCCCEEEEECCCCCCHHCCEEEEEEEHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHH
LIQHGFINRTPRGRVATRAAYEHFGRIAPPSSSQGNLF
HHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA