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The map label for this gene is allR [H]

Identifier: 78221961

GI number: 78221961

Start: 815945

End: 816712

Strand: Reverse

Name: allR [H]

Synonym: Gmet_0741

Alternate gene names: 78221961

Gene position: 816712-815945 (Counterclockwise)

Preceding gene: 78221962

Following gene: 78221960

Centisome position: 20.43

GC content: 60.55

Gene sequence:

>768_bases
ATGACCAGGGAAAAGAGTTCATACGCGGTACAAACCGTTGAAAAGGCCCTGGATATTCTCGAAACGCTCACCGAGGAAAG
CCGGCACGCCACCCTTCCCTACCTTGCGGAGAGGCTCGATCTCTCCCGCAACAAGGCTTTCCGTCTTCTGGCAACCCTCG
AGAGCAAGGGGCTCGTGGAGCGTGACGATGCCAGTGGCATCTACCGCCTCGGGATTTCGTCGGTGGAACTGGCCCAGAGG
CTCCTCAACAGCACGAGCCTCATCCGGCATTCCCACCCGGTCATGGAGAAGCTGGCGCGCAAGCATGACGAGGCGGTCTA
CATCGCGGTCCTCAAGGGAGAGGAAGTCCTCTTTCTCGACATGGTCGACTGCGATCAGGCCATCAAAACCGCCCCCCTTG
TCGGCAAGCGCTTCCCCTTCTTCACCAACGCGGCAGGCAAGGCCATCAAGTCGCTGGAGTCGGCTGACCTCCTGGAGAAA
TTCTTCAAGAAACGGAGAAATGGCGGGACCCCTGATCCGGCCCTTCTCCAGACTGAACTGACGGCGATTCGGGAGCGCGG
TTTCGCCGTCGATTTCGACGGGCTCGGCGAAGGGATCGTCACGGTCGCCGTGGCGGTACGGGATTACGCCGGCAAGGTAA
TCGGCGCCCTTACCATGCTCGGACCGTCGTTCAGGCTGATGGCCTCGCGGCTGGAGGAGGAGATCATCCCTTCCCTCCGG
GAGGGCGCCGAGATGCTTTCCCTGAAGTTTGGCTACGCAAAGCTTTAG

Upstream 100 bases:

>100_bases
TTGATGTTGACGCAAGTAAAACGTCGTGCTAAAAAATAATCACACAATATAACATTGTTTATAAAACAGCCTTGCACACC
ATTCTTGACGGAAGGTAACG

Downstream 100 bases:

>100_bases
GACCAGAGGAGTAACGGGACCAACTATTCGACGAAAGGAGGGGAGACACGACGGATACGGAAGTTGATACAGAATCGGAG
CGGGACGCCGCTCCATGGAT

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: Negative regulator of allantoin and glyoxylate utilization operons [H]

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MTREKSSYAVQTVEKALDILETLTEESRHATLPYLAERLDLSRNKAFRLLATLESKGLVERDDASGIYRLGISSVELAQR
LLNSTSLIRHSHPVMEKLARKHDEAVYIAVLKGEEVLFLDMVDCDQAIKTAPLVGKRFPFFTNAAGKAIKSLESADLLEK
FFKKRRNGGTPDPALLQTELTAIRERGFAVDFDGLGEGIVTVAVAVRDYAGKVIGALTMLGPSFRLMASRLEEEIIPSLR
EGAEMLSLKFGYAKL

Sequences:

>Translated_255_residues
MTREKSSYAVQTVEKALDILETLTEESRHATLPYLAERLDLSRNKAFRLLATLESKGLVERDDASGIYRLGISSVELAQR
LLNSTSLIRHSHPVMEKLARKHDEAVYIAVLKGEEVLFLDMVDCDQAIKTAPLVGKRFPFFTNAAGKAIKSLESADLLEK
FFKKRRNGGTPDPALLQTELTAIRERGFAVDFDGLGEGIVTVAVAVRDYAGKVIGALTMLGPSFRLMASRLEEEIIPSLR
EGAEMLSLKFGYAKL
>Mature_254_residues
TREKSSYAVQTVEKALDILETLTEESRHATLPYLAERLDLSRNKAFRLLATLESKGLVERDDASGIYRLGISSVELAQRL
LNSTSLIRHSHPVMEKLARKHDEAVYIAVLKGEEVLFLDMVDCDQAIKTAPLVGKRFPFFTNAAGKAIKSLESADLLEKF
FKKRRNGGTPDPALLQTELTAIRERGFAVDFDGLGEGIVTVAVAVRDYAGKVIGALTMLGPSFRLMASRLEEEIIPSLRE
GAEMLSLKFGYAKL

Specific function: Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=254, Percent_Identity=26.7716535433071, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1786715, Length=227, Percent_Identity=25.9911894273128, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1786468, Length=252, Percent_Identity=26.1904761904762, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87082359, Length=231, Percent_Identity=24.6753246753247, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789999, Length=266, Percent_Identity=27.4436090225564, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1790752, Length=225, Percent_Identity=22.6666666666667, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28216; Mature: 28085

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTREKSSYAVQTVEKALDILETLTEESRHATLPYLAERLDLSRNKAFRLLATLESKGLVE
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
RDDASGIYRLGISSVELAQRLLNSTSLIRHSHPVMEKLARKHDEAVYIAVLKGEEVLFLD
CCCCCCEEHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEEECCCEEEEEE
MVDCDQAIKTAPLVGKRFPFFTNAAGKAIKSLESADLLEKFFKKRRNGGTPDPALLQTEL
EHHHHHHHHHCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
TAIRERGFAVDFDGLGEGIVTVAVAVRDYAGKVIGALTMLGPSFRLMASRLEEEIIPSLR
HHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
EGAEMLSLKFGYAKL
HHHHHHHHHCCCCCC
>Mature Secondary Structure 
TREKSSYAVQTVEKALDILETLTEESRHATLPYLAERLDLSRNKAFRLLATLESKGLVE
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
RDDASGIYRLGISSVELAQRLLNSTSLIRHSHPVMEKLARKHDEAVYIAVLKGEEVLFLD
CCCCCCEEHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEEECCCEEEEEE
MVDCDQAIKTAPLVGKRFPFFTNAAGKAIKSLESADLLEKFFKKRRNGGTPDPALLQTEL
EHHHHHHHHHCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
TAIRERGFAVDFDGLGEGIVTVAVAVRDYAGKVIGALTMLGPSFRLMASRLEEEIIPSLR
HHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
EGAEMLSLKFGYAKL
HHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA