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The map label for this gene is murI

Identifier: 78221768

GI number: 78221768

Start: 583981

End: 584811

Strand: Direct

Name: murI

Synonym: Gmet_0547

Alternate gene names: 78221768

Gene position: 583981-584811 (Clockwise)

Preceding gene: 78221762

Following gene: 78221769

Centisome position: 14.61

GC content: 66.19

Gene sequence:

>831_bases
ATGCGCGGAGAAGAAACCTTGCCCTGGAAAGCCATCGGCATCTTTGACTCGGGGGTCGGCGGCCTCACCGTCCTCAAGGA
GATCATCAAGGCCCTCCCCCAGGAGGACACCATCTATTTCGGCGACACGGCCCGGGTTCCCTACGGGACCAAGTCCCCGG
AAACCGTCACCCGCTACAGCCTCGAAATCGCTTCGTTCCTCGTGCACCGCGATATCAAACTCCTGGTGGTGGCCTGCAAC
ACCGCCTCGGCCTGCGCCCTGGAAGCCCTGCAGCAGACTCTCTCAATCCCCGTGGTCGGCGTCATCGAGCCTGGGGCCCG
CCGGGCCGCCGCCGTCACCCGCAGCGGCAGGGTGGGGGTGATCGGCACCGAGGGGACCATCCGGAGCAGCGCCTATGCCA
AGGCCATCAAGCGGATTAACCCCGAGGTGGAGGTGGTGACCCGGGCCTGTCCCCTCTTCGTTCCCCTGGCCGAGGAGGGG
TGGACCGACAACGAGGTGGCGCACCTGACCGCCCGCACCTACCTGTCGGGGCTGCGGGAGGCGGGGGTCGACACCCTGGT
CCTCGGCTGCACCCACTATCCCCTTCTCAAGCGGGTCATCGGCGAGACCATCGGCGAGGAGGTGAAGTTGGTGGACTCTG
CCGAGGAAACGGCCCGCATCGTGGCGGAAATCCTCCGGGGGGGGGAACTCCTGCGTCCCACCTCCGAGCAGGGAAACCAC
CACTACTTCGTGTCCGATGTGCCGGCGGGGTTCATCCGGGTCGGTAACCGGTTCCTCGGGGGGAAACTGGGCGACGTCTA
TCAGGTGAGCCTCGAGGCGGAAAAGGAATAG

Upstream 100 bases:

>100_bases
CGGGGGGCAAATACCTTGACATTTTGTCGACGGCTCACCTACTATATATATTTTTTATTATTCCAACAACCGAAAGCACC
GGCCGTTCGGGTCGGACCGG

Downstream 100 bases:

>100_bases
GAGCCATGAAGAGAACCAAGCCCCACAGCCGGGAGCAACTCGTGCTCGCCGCCTTCCTCATCGCCGCCATTGTGTTCGGC
CTCCTGTTTTTCGGCAAGTA

Product: glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MRGEETLPWKAIGIFDSGVGGLTVLKEIIKALPQEDTIYFGDTARVPYGTKSPETVTRYSLEIASFLVHRDIKLLVVACN
TASACALEALQQTLSIPVVGVIEPGARRAAAVTRSGRVGVIGTEGTIRSSAYAKAIKRINPEVEVVTRACPLFVPLAEEG
WTDNEVAHLTARTYLSGLREAGVDTLVLGCTHYPLLKRVIGETIGEEVKLVDSAEETARIVAEILRGGELLRPTSEQGNH
HYFVSDVPAGFIRVGNRFLGGKLGDVYQVSLEAEKE

Sequences:

>Translated_276_residues
MRGEETLPWKAIGIFDSGVGGLTVLKEIIKALPQEDTIYFGDTARVPYGTKSPETVTRYSLEIASFLVHRDIKLLVVACN
TASACALEALQQTLSIPVVGVIEPGARRAAAVTRSGRVGVIGTEGTIRSSAYAKAIKRINPEVEVVTRACPLFVPLAEEG
WTDNEVAHLTARTYLSGLREAGVDTLVLGCTHYPLLKRVIGETIGEEVKLVDSAEETARIVAEILRGGELLRPTSEQGNH
HYFVSDVPAGFIRVGNRFLGGKLGDVYQVSLEAEKE
>Mature_276_residues
MRGEETLPWKAIGIFDSGVGGLTVLKEIIKALPQEDTIYFGDTARVPYGTKSPETVTRYSLEIASFLVHRDIKLLVVACN
TASACALEALQQTLSIPVVGVIEPGARRAAAVTRSGRVGVIGTEGTIRSSAYAKAIKRINPEVEVVTRACPLFVPLAEEG
WTDNEVAHLTARTYLSGLREAGVDTLVLGCTHYPLLKRVIGETIGEEVKLVDSAEETARIVAEILRGGELLRPTSEQGNH
HYFVSDVPAGFIRVGNRFLGGKLGDVYQVSLEAEKE

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family

Homologues:

Organism=Escherichia coli, GI87082355, Length=221, Percent_Identity=37.5565610859729, Blast_Score=112, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURI_GEOMG (Q39Y84)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_383515.1
- HSSP:   P94556
- ProteinModelPortal:   Q39Y84
- SMR:   Q39Y84
- STRING:   Q39Y84
- GeneID:   3738381
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_0547
- NMPDR:   fig|269799.3.peg.575
- eggNOG:   COG0796
- HOGENOM:   HBG645102
- OMA:   CGHIPYG
- PhylomeDB:   Q39Y84
- ProtClustDB:   PRK00865
- BioCyc:   GMET269799:GMET_0547-MONOMER
- HAMAP:   MF_00258
- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR018187
- InterPro:   IPR004391
- Gene3D:   G3DSA:3.40.50.1860
- TIGRFAMs:   TIGR00067

Pfam domain/function: PF01177 Asp_Glu_race; SSF53681 Asp/Glu_race

EC number: =5.1.1.3

Molecular weight: Translated: 29801; Mature: 29801

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00923 ASP_GLU_RACEMASE_1; PS00924 ASP_GLU_RACEMASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGEETLPWKAIGIFDSGVGGLTVLKEIIKALPQEDTIYFGDTARVPYGTKSPETVTRYS
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCHHHHHH
LEIASFLVHRDIKLLVVACNTASACALEALQQTLSIPVVGVIEPGARRAAAVTRSGRVGV
HHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCCCEEE
IGTEGTIRSSAYAKAIKRINPEVEVVTRACPLFVPLAEEGWTDNEVAHLTARTYLSGLRE
EECCCCHHHHHHHHHHHHCCCHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHH
AGVDTLVLGCTHYPLLKRVIGETIGEEVKLVDSAEETARIVAEILRGGELLRPTSEQGNH
CCCCEEEECCCCHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHCCCCEECCCCCCCCE
HYFVSDVPAGFIRVGNRFLGGKLGDVYQVSLEAEKE
EEEECCCCHHHHHHCCHHCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MRGEETLPWKAIGIFDSGVGGLTVLKEIIKALPQEDTIYFGDTARVPYGTKSPETVTRYS
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCHHHHHH
LEIASFLVHRDIKLLVVACNTASACALEALQQTLSIPVVGVIEPGARRAAAVTRSGRVGV
HHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCCCEEE
IGTEGTIRSSAYAKAIKRINPEVEVVTRACPLFVPLAEEGWTDNEVAHLTARTYLSGLRE
EECCCCHHHHHHHHHHHHCCCHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHH
AGVDTLVLGCTHYPLLKRVIGETIGEEVKLVDSAEETARIVAEILRGGELLRPTSEQGNH
CCCCEEEECCCCHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHCCCCEECCCCCCCCE
HYFVSDVPAGFIRVGNRFLGGKLGDVYQVSLEAEKE
EEEECCCCHHHHHHCCHHCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA