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The map label for this gene is arsC [H]

Identifier: 78221742

GI number: 78221742

Start: 558812

End: 559234

Strand: Reverse

Name: arsC [H]

Synonym: Gmet_0521

Alternate gene names: 78221742

Gene position: 559234-558812 (Counterclockwise)

Preceding gene: 78221743

Following gene: 78221741

Centisome position: 13.99

GC content: 60.05

Gene sequence:

>423_bases
ATGAAACATCGCGTCCTCTTCCTCTGCACCCACAACGCCAACCGCTCCCAGATGGCCGAGGGGCTGGCAAACCATTTTCT
CGGCGGACAATGGGAGGCCTTCTCCGCCGGCACGGAGGCAACCGCCGTCAATCCGCGAGCAATCAGGGTTATGGCTGAAC
TGGGGATCGATATCTCCAATCAGCGTTCCAAGAATCTCGCTGAATTCGACGGGCAGACCTTTGACCGGGTCATCACCCTC
TGCGGCGATGCCACCGAAAAATGTCCCTACTTCGTCGGTGGAGTCCGGCGTGAGCACGTGGGGTTCGACGACCCTTCACG
GGCCACTGGCACCGAAGGGGAAATCATGGCCGAATTTCGTCGGGTCCGGGATGAGATGCGACAGGAGCTGACTGCCCACC
TGAGCGGAGGAACCCATGAGTGA

Upstream 100 bases:

>100_bases
CGCGAACGCCTCGCCGGCTTTGGCCAGGGGAATCGCTGCGCCTGATTTTTTTTGCTTCGCCTCATCCGCGTATCCGGATA
CACACCTCACAGGAGTTTCT

Downstream 100 bases:

>100_bases
GCATGTATCCCGCAACCTATCCTTCCTCGACCGCTGGCTCACCCTCTGGATCTTCGCCGCCATGGCCCTCGGCGTCGGCC
TGGGGTACTTCATCCCGGGC

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MKHRVLFLCTHNANRSQMAEGLANHFLGGQWEAFSAGTEATAVNPRAIRVMAELGIDISNQRSKNLAEFDGQTFDRVITL
CGDATEKCPYFVGGVRREHVGFDDPSRATGTEGEIMAEFRRVRDEMRQELTAHLSGGTHE

Sequences:

>Translated_140_residues
MKHRVLFLCTHNANRSQMAEGLANHFLGGQWEAFSAGTEATAVNPRAIRVMAELGIDISNQRSKNLAEFDGQTFDRVITL
CGDATEKCPYFVGGVRREHVGFDDPSRATGTEGEIMAEFRRVRDEMRQELTAHLSGGTHE
>Mature_140_residues
MKHRVLFLCTHNANRSQMAEGLANHFLGGQWEAFSAGTEATAVNPRAIRVMAELGIDISNQRSKNLAEFDGQTFDRVITL
CGDATEKCPYFVGGVRREHVGFDDPSRATGTEGEIMAEFRRVRDEMRQELTAHLSGGTHE

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 15554; Mature: 15554

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHRVLFLCTHNANRSQMAEGLANHFLGGQWEAFSAGTEATAVNPRAIRVMAELGIDISN
CCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHCCCCCC
QRSKNLAEFDGQTFDRVITLCGDATEKCPYFVGGVRREHVGFDDPSRATGTEGEIMAEFR
CCCCCHHHHCCHHHHHHHHHHCCCCCCCCHHHCCCHHCCCCCCCCCCCCCCCHHHHHHHH
RVRDEMRQELTAHLSGGTHE
HHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKHRVLFLCTHNANRSQMAEGLANHFLGGQWEAFSAGTEATAVNPRAIRVMAELGIDISN
CCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHCCCCCC
QRSKNLAEFDGQTFDRVITLCGDATEKCPYFVGGVRREHVGFDDPSRATGTEGEIMAEFR
CCCCCHHHHCCHHHHHHHHHHCCCCCCCCHHHCCCHHCCCCCCCCCCCCCCCHHHHHHHH
RVRDEMRQELTAHLSGGTHE
HHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895; 9537360 [H]