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The map label for this gene is fliD [H]

Identifier: 78221665

GI number: 78221665

Start: 488384

End: 489847

Strand: Direct

Name: fliD [H]

Synonym: Gmet_0444

Alternate gene names: 78221665

Gene position: 488384-489847 (Clockwise)

Preceding gene: 78221664

Following gene: 78221666

Centisome position: 12.22

GC content: 47.61

Gene sequence:

>1464_bases
GTGTTTGGCGCGGGAATTGCTTTCCATTGTTTGGGAGGAAAAGCCATGGCTAACATCTCAATCAGCGGTTTGGTAACGGG
CCTTGACAGCTCGTCGATCATCTCTCAGCTTATGCAGCTGGAACGGACACCTGAGAGGATCATGAAGGCGAAGCAACAGA
AATATCAGAACCAAATTTCAGAGTTTCAGAAGATAGAAACAGCCCTCAAGAGCTTTCAGAAGGTTGTGAAGGGATTTAAT
ACTCTTGGCAATTTTAAATCAATGCAGACAACAGTGGCAGACAATTCCGTCCTCACTGCGTCTGGCTCCAGTACTGCCAC
GCCGGGAACCCATACAGTACAGGTGACGACCTTGGCAAAAAACCAACGCCAAGTATCCATGGGCGTCGCCAGCCAGACGG
ACAAGGTTTTCAATACCGGGAGCTTCACCATTACTGACAGTGCAGGCAAGACCACGACGGTCAGTATTGCTGAAGGGCAG
AATTCCCTTGGGGATATAGTGTCGGCAATCAACACCTCTGGTGCTAATGTTACCGCATCTATCATCAATGATGGGTCACC
AACCCCCTACCGTTTGGTTGTGACAGGCAAGGATACGAATAACTACACACTGGATTTCTCTGGTTTGACAACTCCTCCTG
CCGGGGGGACCGGTTCGTTGCTCCCAACCATGCTTGGGCCGTCGGATCCGTCGTATCAGGCCGGCACCGCTGCAACTTTG
GTTGTCGATGGTATCACCATGACGAAAACGTCGAATACTGTCACCGATGCTATCCAAGGGATAACATTGAACCTGCTGAA
AGAGGGCAGCACCACTACTGTTAACGTTGCTAACGATACGAGTGCAGTCACAAATAAAATTAATGAATTCATATCTTCAT
ATAACGATGTTATCAATTTGGTAAACAAACAATCTATCTATAACCCGGACACGAAGACTGCAGGCGTGCTCTCAGGAGAT
TCGACAGTAAGGACAATACAGTCAAAGCTCCAGTCACTCCTGTCTACAACCGTTTCAGGCGTTACTGGACCCTACACCAG
TCTTGCCAGTCTCGGGATAACCTCGGACAAGAAAGACGGGACTCTCTCAGTCGATTCCACGGCCCTGTCCTCGGCACTTT
CCACTAATTTTGAAGCTGTTGCCGATCTTTTTACCCATAACACGGGAACCTACACGACGTTGCCAAGTAATCAGTATGGC
ATTGCGCAACAGTTTAATCTCGCAATAGACTCGATGGTGAGTCCCTATATAGGTACTGGCGTGTCAACTAACGGACTCAT
TGAGACGCGTATCAAGGGCCTTAATACTTCAATATCTGACATCAATGACCAGATTGATTCGCTTGAAAGCCGTATAGAGA
AGATGCAGTCTAATCTTCAACTTCAGTTTACCAATATGGAAACTACCGTCAGCAAATTACAGACCCAGGGTAATTCACTT
CTAAGCTACCTGAGCAAGCTGTAA

Upstream 100 bases:

>100_bases
CCCGGATGAACCTCTTTTTTTTGCCGTCATTAAAGTTTTTGCTGCTGTTGCCGATAAGATAGATAAAGGGAATCATGGGC
AATAGATGGAAAGGGTCCCT

Downstream 100 bases:

>100_bases
CGAAGGAGGGGGCATGTACTCGCCGCTTAATCAATATCAGAACAACCAAGTGTTGACAGCTTCCCCAGAGAAGATTCTTA
TCATGCTCTACGACGGGGCG

Product: flagellar hook-associated protein 2-like

Products: NA

Alternate protein names: HAP2; Filament cap protein [H]

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MFGAGIAFHCLGGKAMANISISGLVTGLDSSSIISQLMQLERTPERIMKAKQQKYQNQISEFQKIETALKSFQKVVKGFN
TLGNFKSMQTTVADNSVLTASGSSTATPGTHTVQVTTLAKNQRQVSMGVASQTDKVFNTGSFTITDSAGKTTTVSIAEGQ
NSLGDIVSAINTSGANVTASIINDGSPTPYRLVVTGKDTNNYTLDFSGLTTPPAGGTGSLLPTMLGPSDPSYQAGTAATL
VVDGITMTKTSNTVTDAIQGITLNLLKEGSTTTVNVANDTSAVTNKINEFISSYNDVINLVNKQSIYNPDTKTAGVLSGD
STVRTIQSKLQSLLSTTVSGVTGPYTSLASLGITSDKKDGTLSVDSTALSSALSTNFEAVADLFTHNTGTYTTLPSNQYG
IAQQFNLAIDSMVSPYIGTGVSTNGLIETRIKGLNTSISDINDQIDSLESRIEKMQSNLQLQFTNMETTVSKLQTQGNSL
LSYLSKL

Sequences:

>Translated_487_residues
MFGAGIAFHCLGGKAMANISISGLVTGLDSSSIISQLMQLERTPERIMKAKQQKYQNQISEFQKIETALKSFQKVVKGFN
TLGNFKSMQTTVADNSVLTASGSSTATPGTHTVQVTTLAKNQRQVSMGVASQTDKVFNTGSFTITDSAGKTTTVSIAEGQ
NSLGDIVSAINTSGANVTASIINDGSPTPYRLVVTGKDTNNYTLDFSGLTTPPAGGTGSLLPTMLGPSDPSYQAGTAATL
VVDGITMTKTSNTVTDAIQGITLNLLKEGSTTTVNVANDTSAVTNKINEFISSYNDVINLVNKQSIYNPDTKTAGVLSGD
STVRTIQSKLQSLLSTTVSGVTGPYTSLASLGITSDKKDGTLSVDSTALSSALSTNFEAVADLFTHNTGTYTTLPSNQYG
IAQQFNLAIDSMVSPYIGTGVSTNGLIETRIKGLNTSISDINDQIDSLESRIEKMQSNLQLQFTNMETTVSKLQTQGNSL
LSYLSKL
>Mature_487_residues
MFGAGIAFHCLGGKAMANISISGLVTGLDSSSIISQLMQLERTPERIMKAKQQKYQNQISEFQKIETALKSFQKVVKGFN
TLGNFKSMQTTVADNSVLTASGSSTATPGTHTVQVTTLAKNQRQVSMGVASQTDKVFNTGSFTITDSAGKTTTVSIAEGQ
NSLGDIVSAINTSGANVTASIINDGSPTPYRLVVTGKDTNNYTLDFSGLTTPPAGGTGSLLPTMLGPSDPSYQAGTAATL
VVDGITMTKTSNTVTDAIQGITLNLLKEGSTTTVNVANDTSAVTNKINEFISSYNDVINLVNKQSIYNPDTKTAGVLSGD
STVRTIQSKLQSLLSTTVSGVTGPYTSLASLGITSDKKDGTLSVDSTALSSALSTNFEAVADLFTHNTGTYTTLPSNQYG
IAQQFNLAIDSMVSPYIGTGVSTNGLIETRIKGLNTSISDINDQIDSLESRIEKMQSNLQLQFTNMETTVSKLQTQGNSL
LSYLSKL

Specific function: Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the

COG id: COG1345

COG function: function code N; Flagellar capping protein

Gene ontology:

Cell location: Secreted. Bacterial flagellum [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliD family [H]

Homologues:

Organism=Escherichia coli, GI1788233, Length=496, Percent_Identity=28.6290322580645, Blast_Score=134, Evalue=1e-32,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010810
- InterPro:   IPR010809
- InterPro:   IPR003481 [H]

Pfam domain/function: PF07196 Flagellin_IN; PF07195 FliD_C; PF02465 FliD_N [H]

EC number: NA

Molecular weight: Translated: 51186; Mature: 51186

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGAGIAFHCLGGKAMANISISGLVTGLDSSSIISQLMQLERTPERIMKAKQQKYQNQIS
CCCCCEEEEEECCCEEEEEEEEHEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
EFQKIETALKSFQKVVKGFNTLGNFKSMQTTVADNSVLTASGSSTATPGTHTVQVTTLAK
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEECCCCEEEECCCCCCCCCCEEEEEEEECC
NQRQVSMGVASQTDKVFNTGSFTITDSAGKTTTVSIAEGQNSLGDIVSAINTSGANVTAS
CCHHHHHCCHHCCCHHEECCCEEEECCCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEE
IINDGSPTPYRLVVTGKDTNNYTLDFSGLTTPPAGGTGSLLPTMLGPSDPSYQAGTAATL
EECCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCHHHCCCCCCCCCCCCEEEE
VVDGITMTKTSNTVTDAIQGITLNLLKEGSTTTVNVANDTSAVTNKINEFISSYNDVINL
EEECEEEECCCCHHHHHHCCCEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHH
VNKQSIYNPDTKTAGVLSGDSTVRTIQSKLQSLLSTTVSGVTGPYTSLASLGITSDKKDG
HHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCC
TLSVDSTALSSALSTNFEAVADLFTHNTGTYTTLPSNQYGIAQQFNLAIDSMVSPYIGTG
EEEECHHHHHHHHHCCHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHCCHHCCC
VSTNGLIETRIKGLNTSISDINDQIDSLESRIEKMQSNLQLQFTNMETTVSKLQTQGNSL
CCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHCHHHH
LSYLSKL
HHHHHCC
>Mature Secondary Structure
MFGAGIAFHCLGGKAMANISISGLVTGLDSSSIISQLMQLERTPERIMKAKQQKYQNQIS
CCCCCEEEEEECCCEEEEEEEEHEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
EFQKIETALKSFQKVVKGFNTLGNFKSMQTTVADNSVLTASGSSTATPGTHTVQVTTLAK
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEECCCCEEEECCCCCCCCCCEEEEEEEECC
NQRQVSMGVASQTDKVFNTGSFTITDSAGKTTTVSIAEGQNSLGDIVSAINTSGANVTAS
CCHHHHHCCHHCCCHHEECCCEEEECCCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEE
IINDGSPTPYRLVVTGKDTNNYTLDFSGLTTPPAGGTGSLLPTMLGPSDPSYQAGTAATL
EECCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCHHHCCCCCCCCCCCCEEEE
VVDGITMTKTSNTVTDAIQGITLNLLKEGSTTTVNVANDTSAVTNKINEFISSYNDVINL
EEECEEEECCCCHHHHHHCCCEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHH
VNKQSIYNPDTKTAGVLSGDSTVRTIQSKLQSLLSTTVSGVTGPYTSLASLGITSDKKDG
HHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCC
TLSVDSTALSSALSTNFEAVADLFTHNTGTYTTLPSNQYGIAQQFNLAIDSMVSPYIGTG
EEEECHHHHHHHHHCCHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHCCHHCCC
VSTNGLIETRIKGLNTSISDINDQIDSLESRIEKMQSNLQLQFTNMETTVSKLQTQGNSL
CCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHCHHHH
LSYLSKL
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10678962; 10984043 [H]