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The map label for this gene is murG

Identifier: 78221633

GI number: 78221633

Start: 455619

End: 456713

Strand: Direct

Name: murG

Synonym: Gmet_0412

Alternate gene names: 78221633

Gene position: 455619-456713 (Clockwise)

Preceding gene: 78221632

Following gene: 78221634

Centisome position: 11.4

GC content: 61.28

Gene sequence:

>1095_bases
ATGAGACTTCTGATCGCAGGCGGCGGAACCGGGGGGCATCTCTTCCCCGGCATTGCGGTGGCCGAGGAGTTCCTCTCTCG
CAAGAAAGGGAACGAGGTTCTCTTCGTGGGGACGTGGCGGGGAATCGAGGCACGGGTATTGCCGAAGCTGGGGTACCGGC
TCGAATGCATCACCGCTGCCGGCATCCGTGGCAAGGGGAGCGTTGCCCGGGCCAAGGGGCTTGCCAAGTTCCTCTACGGC
TATGCCCAGTCCCGGAAGATTCTCAAGGAGTTCAAGCCCGATCTGGTCCTGGGCGTGGGGGGGTACGCGTCGGCGCCGGC
GCTGCTTGCAGCCCGGGGGATGCACATTCCGCGCTTCATCCATGAGCAGAATGCAATCCCCGGCTTCACCAACAAGATGC
TTGCCACGGTGGCCGAACGTGTCTTTATCTCTTTGGAAGAGTCACGGAAGTTTTTCCCCGAGGAACGGACGCTGCTGACC
GGGAACCCGCTTCGTCGCCAGATACTGGAACAGGTTGCCCTTGCCCCTCAGGAAGAACGTACCGATGATGCCTTTCACCT
CCTGGTCTTTGGCGGAAGCGCCGGGGCTCACCGGATCAACCTGATCATGGGAGAAGTTCTGCCCCATCTGGAGGACGTGA
AGGAGAGGCTGCGGATCACCCACCAGACCGGCGAGAATGATCTGGAAGATGTGACCTCGGCCTATGAGGAGCAGGGAGTT
GCCGCCGACGTGGTGGCGTTCATTGATTCCATGGCCGATGCCTACCGTTGGGCCGACCTCGTGGTCTGCCGGGCAGGTGC
CACCACCATCGCCGAAATCACCGCCTGCGGCAAGCCGTGCATTTTCATCCCGTATCCCCATGCCGTGGACGACCACCAGC
GTCGTAACGCCGAGGCGCTCCTCAAGCGGGGGGCCGGGTTTGTGATTATCGAGCAGGAGCTTTCTGGCGAGGTGTTGGCG
AAAACCATCCGTGATCTGATGGCCGACCCGGCGCGGCTGAAAAGCGTCGGAGAGGCAGCCCAAGGGCTTGCGCGGCTCGA
TGCGGCCCAGGTGATCGTTGACGAAATGATGACAAGTAAAAGGAAAGAAAAATAG

Upstream 100 bases:

>100_bases
TGGCGCTGCCGTTTATCAGCTATGGCGGCAGTTCCCTCATTGTAACGCTCTTCGCGGTGGGGATTCTCCTCAACGTGTCA
ACCCGGATGAAGGGGACGCC

Downstream 100 bases:

>100_bases
ATATGTACGGAAAGATCGAAAAAATCCACTTCGTCGGCATCGGCGGCATCGGTATGAGCGGCATCGCCGAGGTGCTCCTG
AACCTGGGGTACAAGGTGTC

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MRLLIAGGGTGGHLFPGIAVAEEFLSRKKGNEVLFVGTWRGIEARVLPKLGYRLECITAAGIRGKGSVARAKGLAKFLYG
YAQSRKILKEFKPDLVLGVGGYASAPALLAARGMHIPRFIHEQNAIPGFTNKMLATVAERVFISLEESRKFFPEERTLLT
GNPLRRQILEQVALAPQEERTDDAFHLLVFGGSAGAHRINLIMGEVLPHLEDVKERLRITHQTGENDLEDVTSAYEEQGV
AADVVAFIDSMADAYRWADLVVCRAGATTIAEITACGKPCIFIPYPHAVDDHQRRNAEALLKRGAGFVIIEQELSGEVLA
KTIRDLMADPARLKSVGEAAQGLARLDAAQVIVDEMMTSKRKEK

Sequences:

>Translated_364_residues
MRLLIAGGGTGGHLFPGIAVAEEFLSRKKGNEVLFVGTWRGIEARVLPKLGYRLECITAAGIRGKGSVARAKGLAKFLYG
YAQSRKILKEFKPDLVLGVGGYASAPALLAARGMHIPRFIHEQNAIPGFTNKMLATVAERVFISLEESRKFFPEERTLLT
GNPLRRQILEQVALAPQEERTDDAFHLLVFGGSAGAHRINLIMGEVLPHLEDVKERLRITHQTGENDLEDVTSAYEEQGV
AADVVAFIDSMADAYRWADLVVCRAGATTIAEITACGKPCIFIPYPHAVDDHQRRNAEALLKRGAGFVIIEQELSGEVLA
KTIRDLMADPARLKSVGEAAQGLARLDAAQVIVDEMMTSKRKEK
>Mature_364_residues
MRLLIAGGGTGGHLFPGIAVAEEFLSRKKGNEVLFVGTWRGIEARVLPKLGYRLECITAAGIRGKGSVARAKGLAKFLYG
YAQSRKILKEFKPDLVLGVGGYASAPALLAARGMHIPRFIHEQNAIPGFTNKMLATVAERVFISLEESRKFFPEERTLLT
GNPLRRQILEQVALAPQEERTDDAFHLLVFGGSAGAHRINLIMGEVLPHLEDVKERLRITHQTGENDLEDVTSAYEEQGV
AADVVAFIDSMADAYRWADLVVCRAGATTIAEITACGKPCIFIPYPHAVDDHQRRNAEALLKRGAGFVIIEQELSGEVLA
KTIRDLMADPARLKSVGEAAQGLARLDAAQVIVDEMMTSKRKEK

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=355, Percent_Identity=39.4366197183099, Blast_Score=224, Evalue=5e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_GEOMG (Q39YL9)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_383380.1
- ProteinModelPortal:   Q39YL9
- SMR:   Q39YL9
- STRING:   Q39YL9
- GeneID:   3738167
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_0412
- NMPDR:   fig|269799.3.peg.440
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- PhylomeDB:   Q39YL9
- ProtClustDB:   PRK00726
- BioCyc:   GMET269799:GMET_0412-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 39782; Mature: 39782

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLIAGGGTGGHLFPGIAVAEEFLSRKKGNEVLFVGTWRGIEARVLPKLGYRLECITAA
CEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHCCCEEEEEEEC
GIRGKGSVARAKGLAKFLYGYAQSRKILKEFKPDLVLGVGGYASAPALLAARGMHIPRFI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHCCCCCHHHH
HEQNAIPGFTNKMLATVAERVFISLEESRKFFPEERTLLTGNPLRRQILEQVALAPQEER
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHCCCCCCC
TDDAFHLLVFGGSAGAHRINLIMGEVLPHLEDVKERLRITHQTGENDLEDVTSAYEEQGV
CCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
AADVVAFIDSMADAYRWADLVVCRAGATTIAEITACGKPCIFIPYPHAVDDHQRRNAEAL
HHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHCCCCEEEECCCCCCCHHHHCCHHHH
LKRGAGFVIIEQELSGEVLAKTIRDLMADPARLKSVGEAAQGLARLDAAQVIVDEMMTSK
HHCCCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKEK
HCCC
>Mature Secondary Structure
MRLLIAGGGTGGHLFPGIAVAEEFLSRKKGNEVLFVGTWRGIEARVLPKLGYRLECITAA
CEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHCCCEEEEEEEC
GIRGKGSVARAKGLAKFLYGYAQSRKILKEFKPDLVLGVGGYASAPALLAARGMHIPRFI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHCCCCCHHHH
HEQNAIPGFTNKMLATVAERVFISLEESRKFFPEERTLLTGNPLRRQILEQVALAPQEER
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHCCCCCCC
TDDAFHLLVFGGSAGAHRINLIMGEVLPHLEDVKERLRITHQTGENDLEDVTSAYEEQGV
CCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
AADVVAFIDSMADAYRWADLVVCRAGATTIAEITACGKPCIFIPYPHAVDDHQRRNAEAL
HHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHCCCCEEEECCCCCCCHHHHCCHHHH
LKRGAGFVIIEQELSGEVLAKTIRDLMADPARLKSVGEAAQGLARLDAAQVIVDEMMTSK
HHCCCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKEK
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA