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The map label for this gene is murA [H]

Identifier: 78221603

GI number: 78221603

Start: 426445

End: 427731

Strand: Direct

Name: murA [H]

Synonym: Gmet_0382

Alternate gene names: 78221603

Gene position: 426445-427731 (Clockwise)

Preceding gene: 78221602

Following gene: 78221604

Centisome position: 10.67

GC content: 63.09

Gene sequence:

>1287_bases
TTGCACCCCCACATCAATTTCAGAGGCATTCCATTGGACAAGCTGATAATCAAAGGGGGAAAGAAACTGACCGGTGACGT
ATCGGTCAGCGGCTCCAAGAACGCGGCCCTCCCCGTCTTCATTTCCACCATCCTCGCCCCCGGACTCAACGAAATCCGCA
ATGTCCCGTTCCTGCGCGATATCAACACCACCATCAAGGTCCTGGAATCCCTGGGCGCCGTGGTGGAGGGAAACGGCAAC
ATCGTCAAAATCGACACGACCCACGTGAACGACGTGGAGGCCACCTACGATCTGGTAAAGACCATGCGGGCCTCGGTCCT
GGTCCTGGGGCCGCTTTTGGCGCGCCACGGCCGAGCACGGGTCTCCCTCCCCGGCGGCTGCGCCATCGGTGCCCGCCCCA
TCAACCTCCACCTTAAGGGGCTCGCGGCCCTGGGTGCCGACATCCGGCTGGAGCACGGCTACGTGGAGGCCAAGGCGAAA
AAGCTGAAAGGGGCGAGGATCAACTTCGACATCGCCACCGTGGGGGGTACCGAGCAGCTTATGATGGCGGCTGCCCTGGC
CAAGGGTGAGACGATTCTGGAGAACGCTGCCCGGGAGCCGGAGATCATCGACCTGGCCGACATCCTGAACAGGATGGGGG
CCAGGATCGACGGGGCCGGCACCGACACCATCCGGATCATCGGGGTGAAGGAGCTGGCGCCGGTCGTCCACGACGTCATG
CCCGACCGGATCGAGGCCGGCACCTTCATGGTGGCGGCGGCCATTACCGGCGGCGACATCAAGATTCACAACATGAAGCT
GGAGCACCTGGACGCCCTCGTCTTCAAGCTCCAGGATGCCGGCGTGGAGATCATCAACCGTGACAACGTGGTGCGGGTCA
AGGGTCCCCGGCGCCCCAGGGCCATCAACATCAAGACCCGTCCCTATCCCGGCTTCCCCACCGACATGCAGGCCCAGTTC
ATGGCCCTCATGTGCGTGGCCGACGGGGCGAGCGTCATCAGCGAGAACATCTTCGAGAACCGCTTCATGCACGTTTCGGA
GTTGCTGCGCTTCGGGGCCGACATAACCATTGAGGGGAACACCGCCACCGTGAAGGGGGTGAAGAAGCTCTCCGGCGCGC
CGGTCATGGCCACGGATCTGCGGGCCTCGGCCTCGCTGATCCTGGCCGGGCTTGCTGCCGACAACACCACGGAGATCTCC
CGTATCTACCACCTGGACCGGGGGTATGATTCCATCGAGAAGAAGCTGGCCGGCCTCGGGGCCGACATCAAACGTGTAAA
GGAGTGA

Upstream 100 bases:

>100_bases
CACCGGCTGCTTTACGGCCAAGGATCTCAACGGCATCGACCGGGTGGTCGGCGGACGGATTCCGTAGTGGCGTGATTCAT
CACGTCCCGGGTGCAACGAA

Downstream 100 bases:

>100_bases
GCCGGCGGCGGGAGCGGGTGCCATTGTTGGTCCCCGGTCCCTGGTCCCCGGTCCCTTAGTTTTATGAGCGACTTTCTTAC
CATCGCCATCCCCAAGGGGC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MHPHINFRGIPLDKLIIKGGKKLTGDVSVSGSKNAALPVFISTILAPGLNEIRNVPFLRDINTTIKVLESLGAVVEGNGN
IVKIDTTHVNDVEATYDLVKTMRASVLVLGPLLARHGRARVSLPGGCAIGARPINLHLKGLAALGADIRLEHGYVEAKAK
KLKGARINFDIATVGGTEQLMMAAALAKGETILENAAREPEIIDLADILNRMGARIDGAGTDTIRIIGVKELAPVVHDVM
PDRIEAGTFMVAAAITGGDIKIHNMKLEHLDALVFKLQDAGVEIINRDNVVRVKGPRRPRAINIKTRPYPGFPTDMQAQF
MALMCVADGASVISENIFENRFMHVSELLRFGADITIEGNTATVKGVKKLSGAPVMATDLRASASLILAGLAADNTTEIS
RIYHLDRGYDSIEKKLAGLGADIKRVKE

Sequences:

>Translated_428_residues
MHPHINFRGIPLDKLIIKGGKKLTGDVSVSGSKNAALPVFISTILAPGLNEIRNVPFLRDINTTIKVLESLGAVVEGNGN
IVKIDTTHVNDVEATYDLVKTMRASVLVLGPLLARHGRARVSLPGGCAIGARPINLHLKGLAALGADIRLEHGYVEAKAK
KLKGARINFDIATVGGTEQLMMAAALAKGETILENAAREPEIIDLADILNRMGARIDGAGTDTIRIIGVKELAPVVHDVM
PDRIEAGTFMVAAAITGGDIKIHNMKLEHLDALVFKLQDAGVEIINRDNVVRVKGPRRPRAINIKTRPYPGFPTDMQAQF
MALMCVADGASVISENIFENRFMHVSELLRFGADITIEGNTATVKGVKKLSGAPVMATDLRASASLILAGLAADNTTEIS
RIYHLDRGYDSIEKKLAGLGADIKRVKE
>Mature_428_residues
MHPHINFRGIPLDKLIIKGGKKLTGDVSVSGSKNAALPVFISTILAPGLNEIRNVPFLRDINTTIKVLESLGAVVEGNGN
IVKIDTTHVNDVEATYDLVKTMRASVLVLGPLLARHGRARVSLPGGCAIGARPINLHLKGLAALGADIRLEHGYVEAKAK
KLKGARINFDIATVGGTEQLMMAAALAKGETILENAAREPEIIDLADILNRMGARIDGAGTDTIRIIGVKELAPVVHDVM
PDRIEAGTFMVAAAITGGDIKIHNMKLEHLDALVFKLQDAGVEIINRDNVVRVKGPRRPRAINIKTRPYPGFPTDMQAQF
MALMCVADGASVISENIFENRFMHVSELLRFGADITIEGNTATVKGVKKLSGAPVMATDLRASASLILAGLAADNTTEIS
RIYHLDRGYDSIEKKLAGLGADIKRVKE

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=418, Percent_Identity=56.2200956937799, Blast_Score=447, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45890; Mature: 45890

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPHINFRGIPLDKLIIKGGKKLTGDVSVSGSKNAALPVFISTILAPGLNEIRNVPFLRD
CCCCCCCCCCCHHHHHHCCCCEEECEEEECCCCCCCHHHHHHHHHCCCHHHHHCCCCEEH
INTTIKVLESLGAVVEGNGNIVKIDTTHVNDVEATYDLVKTMRASVLVLGPLLARHGRAR
HHHHHHHHHHCCCEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VSLPGGCAIGARPINLHLKGLAALGADIRLEHGYVEAKAKKLKGARINFDIATVGGTEQL
EECCCCCEECCEEEEEEEEEHHHCCCCEEEECCCHHHHHHHCCCCEEEEEEEECCCHHHH
MMAAALAKGETILENAAREPEIIDLADILNRMGARIDGAGTDTIRIIGVKELAPVVHDVM
HHHHHHHCCHHHHHHCCCCCCEEEHHHHHHHHCCEECCCCCCEEEEEEHHHHHHHHHHHC
PDRIEAGTFMVAAAITGGDIKIHNMKLEHLDALVFKLQDAGVEIINRDNVVRVKGPRRPR
CCHHCCCEEEEEEEEECCEEEEEEEEHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCCC
AINIKTRPYPGFPTDMQAQFMALMCVADGASVISENIFENRFMHVSELLRFGADITIEGN
EEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
TATVKGVKKLSGAPVMATDLRASASLILAGLAADNTTEISRIYHLDRGYDSIEKKLAGLG
CEEEHHHHHHCCCCEEEHHHHCCCEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHCC
ADIKRVKE
CHHHHHCC
>Mature Secondary Structure
MHPHINFRGIPLDKLIIKGGKKLTGDVSVSGSKNAALPVFISTILAPGLNEIRNVPFLRD
CCCCCCCCCCCHHHHHHCCCCEEECEEEECCCCCCCHHHHHHHHHCCCHHHHHCCCCEEH
INTTIKVLESLGAVVEGNGNIVKIDTTHVNDVEATYDLVKTMRASVLVLGPLLARHGRAR
HHHHHHHHHHCCCEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VSLPGGCAIGARPINLHLKGLAALGADIRLEHGYVEAKAKKLKGARINFDIATVGGTEQL
EECCCCCEECCEEEEEEEEEHHHCCCCEEEECCCHHHHHHHCCCCEEEEEEEECCCHHHH
MMAAALAKGETILENAAREPEIIDLADILNRMGARIDGAGTDTIRIIGVKELAPVVHDVM
HHHHHHHCCHHHHHHCCCCCCEEEHHHHHHHHCCEECCCCCCEEEEEEHHHHHHHHHHHC
PDRIEAGTFMVAAAITGGDIKIHNMKLEHLDALVFKLQDAGVEIINRDNVVRVKGPRRPR
CCHHCCCEEEEEEEEECCEEEEEEEEHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCCC
AINIKTRPYPGFPTDMQAQFMALMCVADGASVISENIFENRFMHVSELLRFGADITIEGN
EEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
TATVKGVKKLSGAPVMATDLRASASLILAGLAADNTTEISRIYHLDRGYDSIEKKLAGLG
CEEEHHHHHHCCCCEEEHHHHCCCEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHCC
ADIKRVKE
CHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA