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The map label for this gene is sucD1 [H]

Identifier: 78221529

GI number: 78221529

Start: 344237

End: 346966

Strand: Direct

Name: sucD1 [H]

Synonym: Gmet_0306

Alternate gene names: 78221529

Gene position: 344237-346966 (Clockwise)

Preceding gene: 78221528

Following gene: 78221530

Centisome position: 8.61

GC content: 63.74

Gene sequence:

>2730_bases
ATGAACTATCAAAATAATCCCTTTCCCTACCACGTCGGTGTCCAGTCGCTCCACGAGCTGGCCAACAAGCATTCCCGGGT
CTGCATCATGAACATCCGGGGGACCGAGAGCTCACTCGTCACCCCCGTCTCCCACGCTTACAGCGGCGGGAACGTGGTTG
CCGGGGTCCAGTACGGTGAGTCGGGCGGAACCTTCGAGACCCCCGTGGGGGACATCCCGGTCTTCGGCAGCATCTCCGAC
GTCATCAGGGCTGGCATCCACTTCGACACCGGCGTGGTCTATCTCCCCCCCAGCGCCGTTTCCCACGCGGTGTCGGAGAT
GTGCGCCCGTAACGTCAACCTGAAGCGGATCGTCATCGTGACCGAGAAGGTCTCGGCCCGGGATTCGCGCCTGATCCGCT
ACGGCTGCCAGAACGCCAAGGTGGACGTGATCGGGGCCAACACCCTGGGGATTGCCAACTCCTGGGATCAGGTGCGGATC
GGCGGCGCCCTGGGGGGGGACGTTCCGGCCCAGAGCCTGCGGAAGGGGAGTGTCGCCATCTACAGTAACTCCGGCAACTT
CAGCACCACCATCTCCGAGTACCTGAAGACCGCCGGGTTCGGAACCTCCACCATCCTCAGCAGCGGCAAGGACGTCTACA
TCCATTTCGCCCTGGCGGAATTCCTCTACTGCGCCGAGAACGACCCCCGCACCAAGGCCATCGTGGTCTACGTGGAACCG
GGGGGGTACTACGAGAAGCAGGCCCTTGACTGGATCAGCGAGGGGCGCTTCAAGCTGACCAAGCCGATCATCGCCTGCGT
GACCGGGCGGTGGAAGAAGAACCTGACCCGCTCCTGCGGCCACGCCGGAGCCATGGCGGGAAGCGGCGACGACGCCGAGG
CGAAGGAGATCTGGTTCGATGACTTCTTCGGGGTGCCGGTCTTTGATCCGGAGCGGCCAGAGGTCTCCAAACGGGGGATC
CGGATCAGGACCATCCAGGATGTGCCCGAGGCGGTCACCGCCTGCATGGAGCTCATGGGCGAAAATCCCGACTTTCCCTC
CACGGGGGATCTGAGCCTCAAGCCGTGGTTCGTAAACGATCAGGATCTGACCATGCCCCAGCAACTCCGGATGCATCCGG
TGCGGGCCATCTCCCCCTACGGGGAGGAGATCGAGAAGTTCAACAAGCTGGTGGGGGCCCGCATCATGCGGGAGCCCATG
CGCAACCGCTCCGGCGCCAGCGCCATCGACCCGGCCGACTTCACCATCTCGCTCCACGGCCGCAAGCTCCTGGATCTCAT
CGAGGAGCCCTTCGGCGCCGTGACGGCCTACTCGGTCCTGAAGACCATGCCCGACGCCGGTCAGATGGCCGTCATCAACC
CGCTCCTCAACTGGTTCGCGGCCCGGGGAAGCGAGAATATCGCCACTGTGGCTAGGGGGAGGGCCAACGGCTGCACCCCC
AACGCCGCCATCGGCGCCGAGGTGCTCCTTGCGGGGAACAATCCCCTCTTTGAGTCGCTGCGGGCCACGAGCTCCTGGCT
CATCGACCGGTTCTTCCACGAGACCGGGGGAGATCTCTCCATCAACGAGGAGCTCATCGAGAAAGCATGCAGCGACGGCG
AGGGATTCCCCGCCGCCGTGGAGGACCCCCGTTCGGAACAGCTGGCGGAGTATTTCGGAGCACTGCTCCGGACCCATGGC
CAGGAGACAATCCTCACCCGTTTCGCCCAGGTGTATAGCGAGAAACGTCGCGCCGAGGGAGAACCCGTTGATTCCTTCAC
GCTTCTCGCCTCCGCCATCCTCCTGGGGCTCGCCTGGAAACCCCTGGCGGAGCGCCGCATCGCCCGGGAGGTTGCCCAGG
ATCTCGGGACGTACCTGGGGCTGAACGGGATCATCGTTGGCGTCTCTCCCGTGAACCCGGAGCGGAATCCCTTCTGGCAG
AAACTCCACGCGCTCATGGATCCGACGATCCTCTCTACCGATTTTGCGTCCACCTGCTTCCAGGTGCTTTTCAACCGGGT
TCCGCAGGAGCAGGAGCTCTTCACCTACAACGCGCTCCTCAACCTCACCGTCACCAACGGCCCGGGAACCCTCAGCGCCA
AGGGAGCCAAGGAAAGCATCAGCGCCCGCAACCACATCGCCACGGCCTATGCCGGCTTCCTGGCCAACACCGGCCTGGCC
CACGGGGGGAATGGCTTCGAATCGGTGAGCTATCTCCTGGACATCTTCTCGGAGACCGACCCGTACCAGGGAACCCCGGT
GGAGTTGGACCCGGTCCTCAAGGGGCTGGCAGCCCGGGCAACCCAGGAATTCGTGGTCCGGAAGAAGAAGGCGAAGATCG
AAGGGGCGACGGAGCGGATTCCGTGCATCAACCATCCGGTGTTCCGCGACAAGGCCGAAAACCACGACCCGCGAGAGGTC
TTCATCCGCAATCTTCTCAAGGGGAAGGAGATCCAGAATCCCTTCCTGGAGTTCTACCACCACCTGGTCACGGAGCTCCA
CGCCGAGGGGATAACGAGCAACGTCTACTGCGTCAACGTCGATGCGGTCATCGCGTGCATCGCCCTGGATCTCCTCTGGA
AGCAGCTCCGGGACGGCGAAATCAGCGAGCAGGATGCCCAGGAGATCGTCTTCATCATGTTCCTCTACGGCCGGATGGCG
GGGGTGTCGGCCGAAATCGCCGACCACCTGGGCAGGGGACAGGATCTCGACTGCCGCACCAATCCCGGCGAGCTGGTGTA
TCTGGCGTAG

Upstream 100 bases:

>100_bases
TCTTGAGCCGAAACCGGTCGCGGTGGCGCCGAAGCAGATCAAGGCCAAGGCGGCGTGAGCAGCGTCGCGAGACGGAACGA
CTTCACGAAGGAGATAACCA

Downstream 100 bases:

>100_bases
CGTACCCCTCACCCGCCCTTCGGGCACCCTCTCCCCCGGGGAGAGGGGGAAGAAAACGACCGTTGGAACAAGGAGGTGGC
TCCATGGAGGCATTGAAAAA

Product: CoA-binding protein

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha 1; SCS-alpha 1 [H]

Number of amino acids: Translated: 909; Mature: 909

Protein sequence:

>909_residues
MNYQNNPFPYHVGVQSLHELANKHSRVCIMNIRGTESSLVTPVSHAYSGGNVVAGVQYGESGGTFETPVGDIPVFGSISD
VIRAGIHFDTGVVYLPPSAVSHAVSEMCARNVNLKRIVIVTEKVSARDSRLIRYGCQNAKVDVIGANTLGIANSWDQVRI
GGALGGDVPAQSLRKGSVAIYSNSGNFSTTISEYLKTAGFGTSTILSSGKDVYIHFALAEFLYCAENDPRTKAIVVYVEP
GGYYEKQALDWISEGRFKLTKPIIACVTGRWKKNLTRSCGHAGAMAGSGDDAEAKEIWFDDFFGVPVFDPERPEVSKRGI
RIRTIQDVPEAVTACMELMGENPDFPSTGDLSLKPWFVNDQDLTMPQQLRMHPVRAISPYGEEIEKFNKLVGARIMREPM
RNRSGASAIDPADFTISLHGRKLLDLIEEPFGAVTAYSVLKTMPDAGQMAVINPLLNWFAARGSENIATVARGRANGCTP
NAAIGAEVLLAGNNPLFESLRATSSWLIDRFFHETGGDLSINEELIEKACSDGEGFPAAVEDPRSEQLAEYFGALLRTHG
QETILTRFAQVYSEKRRAEGEPVDSFTLLASAILLGLAWKPLAERRIAREVAQDLGTYLGLNGIIVGVSPVNPERNPFWQ
KLHALMDPTILSTDFASTCFQVLFNRVPQEQELFTYNALLNLTVTNGPGTLSAKGAKESISARNHIATAYAGFLANTGLA
HGGNGFESVSYLLDIFSETDPYQGTPVELDPVLKGLAARATQEFVVRKKKAKIEGATERIPCINHPVFRDKAENHDPREV
FIRNLLKGKEIQNPFLEFYHHLVTELHAEGITSNVYCVNVDAVIACIALDLLWKQLRDGEISEQDAQEIVFIMFLYGRMA
GVSAEIADHLGRGQDLDCRTNPGELVYLA

Sequences:

>Translated_909_residues
MNYQNNPFPYHVGVQSLHELANKHSRVCIMNIRGTESSLVTPVSHAYSGGNVVAGVQYGESGGTFETPVGDIPVFGSISD
VIRAGIHFDTGVVYLPPSAVSHAVSEMCARNVNLKRIVIVTEKVSARDSRLIRYGCQNAKVDVIGANTLGIANSWDQVRI
GGALGGDVPAQSLRKGSVAIYSNSGNFSTTISEYLKTAGFGTSTILSSGKDVYIHFALAEFLYCAENDPRTKAIVVYVEP
GGYYEKQALDWISEGRFKLTKPIIACVTGRWKKNLTRSCGHAGAMAGSGDDAEAKEIWFDDFFGVPVFDPERPEVSKRGI
RIRTIQDVPEAVTACMELMGENPDFPSTGDLSLKPWFVNDQDLTMPQQLRMHPVRAISPYGEEIEKFNKLVGARIMREPM
RNRSGASAIDPADFTISLHGRKLLDLIEEPFGAVTAYSVLKTMPDAGQMAVINPLLNWFAARGSENIATVARGRANGCTP
NAAIGAEVLLAGNNPLFESLRATSSWLIDRFFHETGGDLSINEELIEKACSDGEGFPAAVEDPRSEQLAEYFGALLRTHG
QETILTRFAQVYSEKRRAEGEPVDSFTLLASAILLGLAWKPLAERRIAREVAQDLGTYLGLNGIIVGVSPVNPERNPFWQ
KLHALMDPTILSTDFASTCFQVLFNRVPQEQELFTYNALLNLTVTNGPGTLSAKGAKESISARNHIATAYAGFLANTGLA
HGGNGFESVSYLLDIFSETDPYQGTPVELDPVLKGLAARATQEFVVRKKKAKIEGATERIPCINHPVFRDKAENHDPREV
FIRNLLKGKEIQNPFLEFYHHLVTELHAEGITSNVYCVNVDAVIACIALDLLWKQLRDGEISEQDAQEIVFIMFLYGRMA
GVSAEIADHLGRGQDLDCRTNPGELVYLA
>Mature_909_residues
MNYQNNPFPYHVGVQSLHELANKHSRVCIMNIRGTESSLVTPVSHAYSGGNVVAGVQYGESGGTFETPVGDIPVFGSISD
VIRAGIHFDTGVVYLPPSAVSHAVSEMCARNVNLKRIVIVTEKVSARDSRLIRYGCQNAKVDVIGANTLGIANSWDQVRI
GGALGGDVPAQSLRKGSVAIYSNSGNFSTTISEYLKTAGFGTSTILSSGKDVYIHFALAEFLYCAENDPRTKAIVVYVEP
GGYYEKQALDWISEGRFKLTKPIIACVTGRWKKNLTRSCGHAGAMAGSGDDAEAKEIWFDDFFGVPVFDPERPEVSKRGI
RIRTIQDVPEAVTACMELMGENPDFPSTGDLSLKPWFVNDQDLTMPQQLRMHPVRAISPYGEEIEKFNKLVGARIMREPM
RNRSGASAIDPADFTISLHGRKLLDLIEEPFGAVTAYSVLKTMPDAGQMAVINPLLNWFAARGSENIATVARGRANGCTP
NAAIGAEVLLAGNNPLFESLRATSSWLIDRFFHETGGDLSINEELIEKACSDGEGFPAAVEDPRSEQLAEYFGALLRTHG
QETILTRFAQVYSEKRRAEGEPVDSFTLLASAILLGLAWKPLAERRIAREVAQDLGTYLGLNGIIVGVSPVNPERNPFWQ
KLHALMDPTILSTDFASTCFQVLFNRVPQEQELFTYNALLNLTVTNGPGTLSAKGAKESISARNHIATAYAGFLANTGLA
HGGNGFESVSYLLDIFSETDPYQGTPVELDPVLKGLAARATQEFVVRKKKAKIEGATERIPCINHPVFRDKAENHDPREV
FIRNLLKGKEIQNPFLEFYHHLVTELHAEGITSNVYCVNVDAVIACIALDLLWKQLRDGEISEQDAQEIVFIMFLYGRMA
GVSAEIADHLGRGQDLDCRTNPGELVYLA

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Escherichia coli, GI1786949, Length=270, Percent_Identity=28.8888888888889, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17550194, Length=294, Percent_Identity=28.2312925170068, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17553126, Length=288, Percent_Identity=28.4722222222222, Blast_Score=67, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324716, Length=320, Percent_Identity=27.5, Blast_Score=90, Evalue=1e-18,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 99458; Mature: 99458

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYQNNPFPYHVGVQSLHELANKHSRVCIMNIRGTESSLVTPVSHAYSGGNVVAGVQYGE
CCCCCCCCCEEHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHCCCCCEEEEEEECC
SGGTFETPVGDIPVFGSISDVIRAGIHFDTGVVYLPPSAVSHAVSEMCARNVNLKRIVIV
CCCCCCCCCCCCCCCCCHHHHHHHCCEECCCEEEECCHHHHHHHHHHHHCCCCCEEEEEE
TEKVSARDSRLIRYGCQNAKVDVIGANTLGIANSWDQVRIGGALGGDVPAQSLRKGSVAI
ECCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEECCCCCCCCCHHHHCCCCEEE
YSNSGNFSTTISEYLKTAGFGTSTILSSGKDVYIHFALAEFLYCAENDPRTKAIVVYVEP
EECCCCCHHHHHHHHHHCCCCHHHHHCCCCEEEEEHHHHHHHHHCCCCCCCEEEEEEECC
GGYYEKQALDWISEGRFKLTKPIIACVTGRWKKNLTRSCGHAGAMAGSGDDAEAKEIWFD
CCCHHHHHHHHHHCCCEEHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
DFFGVPVFDPERPEVSKRGIRIRTIQDVPEAVTACMELMGENPDFPSTGDLSLKPWFVND
HCCCCCCCCCCCCCHHHCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCEEECC
QDLTMPQQLRMHPVRAISPYGEEIEKFNKLVGARIMREPMRNRSGASAIDPADFTISLHG
CCCCCHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECC
RKLLDLIEEPFGAVTAYSVLKTMPDAGQMAVINPLLNWFAARGSENIATVARGRANGCTP
HHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCC
NAAIGAEVLLAGNNPLFESLRATSSWLIDRFFHETGGDLSINEELIEKACSDGEGFPAAV
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCC
EDPRSEQLAEYFGALLRTHGQETILTRFAQVYSEKRRAEGEPVDSFTLLASAILLGLAWK
CCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
PLAERRIAREVAQDLGTYLGLNGIIVGVSPVNPERNPFWQKLHALMDPTILSTDFASTCF
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
QVLFNRVPQEQELFTYNALLNLTVTNGPGTLSAKGAKESISARNHIATAYAGFLANTGLA
HHHHHHCCCHHHHEEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
HGGNGFESVSYLLDIFSETDPYQGTPVELDPVLKGLAARATQEFVVRKKKAKIEGATERI
CCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCC
PCINHPVFRDKAENHDPREVFIRNLLKGKEIQNPFLEFYHHLVTELHAEGITSNVYCVNV
CCCCCCHHCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEH
DAVIACIALDLLWKQLRDGEISEQDAQEIVFIMFLYGRMAGVSAEIADHLGRGQDLDCRT
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCC
NPGELVYLA
CCCCEEEEC
>Mature Secondary Structure
MNYQNNPFPYHVGVQSLHELANKHSRVCIMNIRGTESSLVTPVSHAYSGGNVVAGVQYGE
CCCCCCCCCEEHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHCCCCCEEEEEEECC
SGGTFETPVGDIPVFGSISDVIRAGIHFDTGVVYLPPSAVSHAVSEMCARNVNLKRIVIV
CCCCCCCCCCCCCCCCCHHHHHHHCCEECCCEEEECCHHHHHHHHHHHHCCCCCEEEEEE
TEKVSARDSRLIRYGCQNAKVDVIGANTLGIANSWDQVRIGGALGGDVPAQSLRKGSVAI
ECCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEECCCCCCCCCHHHHCCCCEEE
YSNSGNFSTTISEYLKTAGFGTSTILSSGKDVYIHFALAEFLYCAENDPRTKAIVVYVEP
EECCCCCHHHHHHHHHHCCCCHHHHHCCCCEEEEEHHHHHHHHHCCCCCCCEEEEEEECC
GGYYEKQALDWISEGRFKLTKPIIACVTGRWKKNLTRSCGHAGAMAGSGDDAEAKEIWFD
CCCHHHHHHHHHHCCCEEHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
DFFGVPVFDPERPEVSKRGIRIRTIQDVPEAVTACMELMGENPDFPSTGDLSLKPWFVND
HCCCCCCCCCCCCCHHHCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCEEECC
QDLTMPQQLRMHPVRAISPYGEEIEKFNKLVGARIMREPMRNRSGASAIDPADFTISLHG
CCCCCHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECC
RKLLDLIEEPFGAVTAYSVLKTMPDAGQMAVINPLLNWFAARGSENIATVARGRANGCTP
HHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCC
NAAIGAEVLLAGNNPLFESLRATSSWLIDRFFHETGGDLSINEELIEKACSDGEGFPAAV
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCC
EDPRSEQLAEYFGALLRTHGQETILTRFAQVYSEKRRAEGEPVDSFTLLASAILLGLAWK
CCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
PLAERRIAREVAQDLGTYLGLNGIIVGVSPVNPERNPFWQKLHALMDPTILSTDFASTCF
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
QVLFNRVPQEQELFTYNALLNLTVTNGPGTLSAKGAKESISARNHIATAYAGFLANTGLA
HHHHHHCCCHHHHEEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
HGGNGFESVSYLLDIFSETDPYQGTPVELDPVLKGLAARATQEFVVRKKKAKIEGATERI
CCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCC
PCINHPVFRDKAENHDPREVFIRNLLKGKEIQNPFLEFYHHLVTELHAEGITSNVYCVNV
CCCCCCHHCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEH
DAVIACIALDLLWKQLRDGEISEQDAQEIVFIMFLYGRMAGVSAEIADHLGRGQDLDCRT
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCC
NPGELVYLA
CCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]