Click here to switch to the map view.

The map label for this gene is ctaC [H]

Identifier: 78221475

GI number: 78221475

Start: 282442

End: 283350

Strand: Direct

Name: ctaC [H]

Synonym: Gmet_0252

Alternate gene names: 78221475

Gene position: 282442-283350 (Clockwise)

Preceding gene: 78221474

Following gene: 78221476

Centisome position: 7.07

GC content: 62.05

Gene sequence:

>909_bases
GTGGACCCGAACCTCTACACCACAACCCGAGCCGTGGACCCCGTTTTCATCTGGATCTTCGGGGTCAGCCTGGTGCTTCT
CCTGGGGATCACCGCCACCATGGTGGGATTCGTCATCCGCTACCGCCGCTCCCGGGCCCCGGAACCCACTTCCCAGGCGG
CAAGCAACATCTGGCTTGAGATAATCTGGACAGCCCTCCCCACCATCATCGTCATGGCGATGTTCTACTACGGCTGGGCC
GGCTACCTGACGCTCCGCAATGTGCCGAAGGACGCCCTGGAGGTGACGGCCACGGCCCGCATGTGGTCCTGGAGCTTCAC
CTACGCCAACGGCAAGACCAGCCCGACGCTCTATGTGCCGGTCGGAAAGCCGGTGCTGGTGCATCTCGTCTCCGAGGATG
TGATCCACGGCTTCTATGTCCCCGCGTTCCGGGTCAAGCACGACGTGGTGCCGGGAATGAAGAACCATGTCTGGTTCGTG
GCGGACAAACCCGGCACCTACGATCTTTTCTGTTCCGTCTACTGCGGCCTCGGCCATTCCGGTATGGTTTCCACGGTGGT
GGCCGTTCCCGAGGCGGAGTTCCAGGCATGGCTCGCGAAGGCGGAGAAAGAGGAGAACCAAGGAGGGGGGAGGGCGCTCC
TGGAGAAGAACGGCTGCCTCGGCTGCCATTCCCTGGACGGGTCGCGAAAGGTGGGGCCAAGCTTCAAGGGGATCTGGGGG
CGGAACGTGACGGTTATGACCGGTGGCGCCGAGCGGACCATCACCGTGGACGAGGAGTACGTGAAACGCTCGATCCGCGA
GCCGGGGGCCGATGTGGTCAAGGGATACCCGCCAGTCATGCCCCCCTATTCAGCCCTCTCCGATAAGGATATCGAGGAAA
TTATGGATTTCCTGAAGGATCTCAAATGA

Upstream 100 bases:

>100_bases
GGGGAGGCTCCTCCGCTGGCTGCTCTTCGTGGCCCTGGTCACCCTGGCGATTTTCATCGGCCTCACCTTTTCCGACGTGC
TCTACCGATAAGGAACTGCC

Downstream 100 bases:

>100_bases
TTGCGGAGGCCAGTCGGCTGCTTCGACCCCGTCTCGCGCTGCTGAACGGCATCGCGGCAGTGGCGGGGTGTCTCCTCGCC
CCGGAGGGAGCGGCGATGTC

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MDPNLYTTTRAVDPVFIWIFGVSLVLLLGITATMVGFVIRYRRSRAPEPTSQAASNIWLEIIWTALPTIIVMAMFYYGWA
GYLTLRNVPKDALEVTATARMWSWSFTYANGKTSPTLYVPVGKPVLVHLVSEDVIHGFYVPAFRVKHDVVPGMKNHVWFV
ADKPGTYDLFCSVYCGLGHSGMVSTVVAVPEAEFQAWLAKAEKEENQGGGRALLEKNGCLGCHSLDGSRKVGPSFKGIWG
RNVTVMTGGAERTITVDEEYVKRSIREPGADVVKGYPPVMPPYSALSDKDIEEIMDFLKDLK

Sequences:

>Translated_302_residues
MDPNLYTTTRAVDPVFIWIFGVSLVLLLGITATMVGFVIRYRRSRAPEPTSQAASNIWLEIIWTALPTIIVMAMFYYGWA
GYLTLRNVPKDALEVTATARMWSWSFTYANGKTSPTLYVPVGKPVLVHLVSEDVIHGFYVPAFRVKHDVVPGMKNHVWFV
ADKPGTYDLFCSVYCGLGHSGMVSTVVAVPEAEFQAWLAKAEKEENQGGGRALLEKNGCLGCHSLDGSRKVGPSFKGIWG
RNVTVMTGGAERTITVDEEYVKRSIREPGADVVKGYPPVMPPYSALSDKDIEEIMDFLKDLK
>Mature_302_residues
MDPNLYTTTRAVDPVFIWIFGVSLVLLLGITATMVGFVIRYRRSRAPEPTSQAASNIWLEIIWTALPTIIVMAMFYYGWA
GYLTLRNVPKDALEVTATARMWSWSFTYANGKTSPTLYVPVGKPVLVHLVSEDVIHGFYVPAFRVKHDVVPGMKNHVWFV
ADKPGTYDLFCSVYCGLGHSGMVSTVVAVPEAEFQAWLAKAEKEENQGGGRALLEKNGCLGCHSLDGSRKVGPSFKGIWG
RNVTVMTGGAERTITVDEEYVKRSIREPGADVVKGYPPVMPPYSALSDKDIEEIMDFLKDLK

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=160, Percent_Identity=26.25, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1786635, Length=207, Percent_Identity=28.0193236714976, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR009056
- InterPro:   IPR003088
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM; PF00034 Cytochrom_C [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 33477; Mature: 33477

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPNLYTTTRAVDPVFIWIFGVSLVLLLGITATMVGFVIRYRRSRAPEPTSQAASNIWLE
CCCCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
IIWTALPTIIVMAMFYYGWAGYLTLRNVPKDALEVTATARMWSWSFTYANGKTSPTLYVP
HHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHEEEEEEEEECCCCCCCEEEEE
VGKPVLVHLVSEDVIHGFYVPAFRVKHDVVPGMKNHVWFVADKPGTYDLFCSVYCGLGHS
CCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCC
GMVSTVVAVPEAEFQAWLAKAEKEENQGGGRALLEKNGCLGCHSLDGSRKVGPSFKGIWG
CHHHHHEECCCHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCC
RNVTVMTGGAERTITVDEEYVKRSIREPGADVVKGYPPVMPPYSALSDKDIEEIMDFLKD
CCEEEEECCCCEEEEECHHHHHHHHHCCCCHHHCCCCCCCCCHHHCCCCCHHHHHHHHHH
LK
CC
>Mature Secondary Structure
MDPNLYTTTRAVDPVFIWIFGVSLVLLLGITATMVGFVIRYRRSRAPEPTSQAASNIWLE
CCCCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
IIWTALPTIIVMAMFYYGWAGYLTLRNVPKDALEVTATARMWSWSFTYANGKTSPTLYVP
HHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHEEEEEEEEECCCCCCCEEEEE
VGKPVLVHLVSEDVIHGFYVPAFRVKHDVVPGMKNHVWFVADKPGTYDLFCSVYCGLGHS
CCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCC
GMVSTVVAVPEAEFQAWLAKAEKEENQGGGRALLEKNGCLGCHSLDGSRKVGPSFKGIWG
CHHHHHEECCCHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCC
RNVTVMTGGAERTITVDEEYVKRSIREPGADVVKGYPPVMPPYSALSDKDIEEIMDFLKD
CCEEEEECCCCEEEEECHHHHHHHHHCCCCHHHCCCCCCCCCHHHCCCCCHHHHHHHHHH
LK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7678007 [H]