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The map label for this gene is rnz [H]

Identifier: 78221412

GI number: 78221412

Start: 218230

End: 219315

Strand: Reverse

Name: rnz [H]

Synonym: Gmet_0188

Alternate gene names: 78221412

Gene position: 219315-218230 (Counterclockwise)

Preceding gene: 78221413

Following gene: 78221410

Centisome position: 5.49

GC content: 67.31

Gene sequence:

>1086_bases
ATGAAACGCCTCCCCTTCCGCTATCTGGAACCCACCTTCTGCGCGGGGCTCCTGGACGACCCGGTCCTCCTGGTGAACGT
CCGCCCCCTGGGGCGCGCCATCCTCGTGGACTGCGGCCAGCTCCACCACCTGGCCAAGCGGGTCCTCAAATCCCTCGACG
CAATCTTTATCACCCACGCCCACATGGACCACTTCATGGGGTTCGACACCCTCGTTCGCCACATCCACGTCTCCCCCCGG
ACGGTGCAGCTTTTCGGCCCGGCAGGGATCGCCGGGAAGGTGACGGCCAAGCTGGCCGGCTACGACTGGAACCTGACCGA
ATCCTACTGGTGCACCTTCCGGGTCCACGAGGTCCATCCCGACAGAATCATCAATTTCACCTTCCCCGGCGCCCAGGGTT
TTCCCTGTCTGCCGGAGGGGGAAACGCCGCGCGCGGGGACGGAGATCTACCGCAACCCGCTTCTCACGGTGGACGCCGCC
ATCTGCGACCACAACGCCATCCCCACCCTCGCCTTCCGGATCACCGAGCGCCCCTCCTTCTGGATCGACGGGGGAAAGAT
CGCGTCGGAAGAGCTTGTGCCGGGGGAGTGGCTGCGGGAGCTGAAGAGCCGCTTTTACCGGGGGGAACTGGATGGCAGAA
CAATCACGGTCCCCTGCCGGACAGCCGCCGGCGGCGTGGAGGAGCGAAGCGTCCACGGCCGGGAGCTCTTCGAGGCGATC
CGGCGGGACCAGGAACCGGCCGGCATCGGCTACCTCACCGACATCGGGGCGAGCGCCGGGAACCTGGCCACGGCGCGGCG
GCTCCTGACAGGCGTCACACTCCTCGCCTGCGAGTGCTCATTCCTGGCCGCGGACAGGGACAAGGCCCGCACCTCCCACC
ACCTCTGCACGACCGACGTCTCGGCCCTCGCCCGGGAGCTCCGCCCCGGCTGGCTCCTCCCCATGCACCTCTCCAAGAGC
TACAACACGAAGGGCCACCTCATCTACGATGAACTGGCCCTTGCGCCGGAAACCCGGCTGATCCGCCTCCCCGAGCACCT
CACCCCCCGGCCACTTCTGCCGACGGAGTTTCCGAAGCTGGGATGA

Upstream 100 bases:

>100_bases
CATTCAATCAGGTTGTCCATGAAGGACCGCCAGCCGATTTACTCCGTGTTCTCCGTCTCTCCGTGTTATTAAACGCTTTT
CAAGGCCGCGAGGCACCACC

Downstream 100 bases:

>100_bases
CTGCGGACAGCCCCGTCAGTGGCATCACCCGTTCTGCCTTGAACCATCCCTCCGTAACGGGACCGGAAACGGTGGTGCAA
CGAAGGCCTCTGATCCCATT

Product: ribonuclease Z

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MKRLPFRYLEPTFCAGLLDDPVLLVNVRPLGRAILVDCGQLHHLAKRVLKSLDAIFITHAHMDHFMGFDTLVRHIHVSPR
TVQLFGPAGIAGKVTAKLAGYDWNLTESYWCTFRVHEVHPDRIINFTFPGAQGFPCLPEGETPRAGTEIYRNPLLTVDAA
ICDHNAIPTLAFRITERPSFWIDGGKIASEELVPGEWLRELKSRFYRGELDGRTITVPCRTAAGGVEERSVHGRELFEAI
RRDQEPAGIGYLTDIGASAGNLATARRLLTGVTLLACECSFLAADRDKARTSHHLCTTDVSALARELRPGWLLPMHLSKS
YNTKGHLIYDELALAPETRLIRLPEHLTPRPLLPTEFPKLG

Sequences:

>Translated_361_residues
MKRLPFRYLEPTFCAGLLDDPVLLVNVRPLGRAILVDCGQLHHLAKRVLKSLDAIFITHAHMDHFMGFDTLVRHIHVSPR
TVQLFGPAGIAGKVTAKLAGYDWNLTESYWCTFRVHEVHPDRIINFTFPGAQGFPCLPEGETPRAGTEIYRNPLLTVDAA
ICDHNAIPTLAFRITERPSFWIDGGKIASEELVPGEWLRELKSRFYRGELDGRTITVPCRTAAGGVEERSVHGRELFEAI
RRDQEPAGIGYLTDIGASAGNLATARRLLTGVTLLACECSFLAADRDKARTSHHLCTTDVSALARELRPGWLLPMHLSKS
YNTKGHLIYDELALAPETRLIRLPEHLTPRPLLPTEFPKLG
>Mature_361_residues
MKRLPFRYLEPTFCAGLLDDPVLLVNVRPLGRAILVDCGQLHHLAKRVLKSLDAIFITHAHMDHFMGFDTLVRHIHVSPR
TVQLFGPAGIAGKVTAKLAGYDWNLTESYWCTFRVHEVHPDRIINFTFPGAQGFPCLPEGETPRAGTEIYRNPLLTVDAA
ICDHNAIPTLAFRITERPSFWIDGGKIASEELVPGEWLRELKSRFYRGELDGRTITVPCRTAAGGVEERSVHGRELFEAI
RRDQEPAGIGYLTDIGASAGNLATARRLLTGVTLLACECSFLAADRDKARTSHHLCTTDVSALARELRPGWLLPMHLSKS
YNTKGHLIYDELALAPETRLIRLPEHLTPRPLLPTEFPKLG

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 40276; Mature: 40276

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLPFRYLEPTFCAGLLDDPVLLVNVRPLGRAILVDCGQLHHLAKRVLKSLDAIFITHA
CCCCCCHHCCHHHHHHCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHEEEHH
HMDHFMGFDTLVRHIHVSPRTVQLFGPAGIAGKVTAKLAGYDWNLTESYWCTFRVHEVHP
HHHHHCCHHHHHHHEECCCCEEEEECCCCCCCEEEEEEECCCCCCCCCEEEEEEEEEECC
DRIINFTFPGAQGFPCLPEGETPRAGTEIYRNPLLTVDAAICDHNAIPTLAFRITERPSF
CEEEEEECCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEHHHHCCCCCCEEEEEEECCCCE
WIDGGKIASEELVPGEWLRELKSRFYRGELDGRTITVPCRTAAGGVEERSVHGRELFEAI
EECCCEECCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHCCCHHHHHHHH
RRDQEPAGIGYLTDIGASAGNLATARRLLTGVTLLACECSFLAADRDKARTSHHLCTTDV
HCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHEEHHHHHHCCCCHHHHHCCCCHHHHH
SALARELRPGWLLPMHLSKSYNTKGHLIYDELALAPETRLIRLPEHLTPRPLLPTEFPKL
HHHHHHCCCCEEEEEECCCCCCCCCCEEEEHHHCCCCCEEEECCCCCCCCCCCCCCCCCC
G
C
>Mature Secondary Structure
MKRLPFRYLEPTFCAGLLDDPVLLVNVRPLGRAILVDCGQLHHLAKRVLKSLDAIFITHA
CCCCCCHHCCHHHHHHCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHEEEHH
HMDHFMGFDTLVRHIHVSPRTVQLFGPAGIAGKVTAKLAGYDWNLTESYWCTFRVHEVHP
HHHHHCCHHHHHHHEECCCCEEEEECCCCCCCEEEEEEECCCCCCCCCEEEEEEEEEECC
DRIINFTFPGAQGFPCLPEGETPRAGTEIYRNPLLTVDAAICDHNAIPTLAFRITERPSF
CEEEEEECCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEHHHHCCCCCCEEEEEEECCCCE
WIDGGKIASEELVPGEWLRELKSRFYRGELDGRTITVPCRTAAGGVEERSVHGRELFEAI
EECCCEECCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHCCCHHHHHHHH
RRDQEPAGIGYLTDIGASAGNLATARRLLTGVTLLACECSFLAADRDKARTSHHLCTTDV
HCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHEEHHHHHHCCCCHHHHHCCCCHHHHH
SALARELRPGWLLPMHLSKSYNTKGHLIYDELALAPETRLIRLPEHLTPRPLLPTEFPKL
HHHHHHCCCCEEEEEECCCCCCCCCCEEEEHHHCCCCCEEEECCCCCCCCCCCCCCCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]