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The map label for this gene is nuoJ [H]

Identifier: 78221390

GI number: 78221390

Start: 194113

End: 194598

Strand: Direct

Name: nuoJ [H]

Synonym: Gmet_0165

Alternate gene names: 78221390

Gene position: 194113-194598 (Clockwise)

Preceding gene: 78221389

Following gene: 78221391

Centisome position: 4.86

GC content: 65.02

Gene sequence:

>486_bases
ATGGAATCGGCCCTCTTCTACATCCTGGCCGTTGTAACGGTCACGGGCACCGCCTTCGCCATCACGGAAAAGCACGCGGT
GCACGCCATCGTCTACCTCGTCACCTCGTTTTTCGCCCTGGCGGTGATCTTCTTCCTGCTCGGAGCGCCGGTGGTGGCAA
TCTTCGAGGTGATCATCTACGCCGGCGCCATCATGGTCCTCTTCCTCTTCGTGATCATGATGCTCGACCTGGGGCACCCG
GAGCGGGCGCGGCTTCCCGGAATCCGGGAGTGGTGGCCGGCCCTTGCCCTCGGCGCCGTGACCCTGGCGTCGGCCCTGGC
CCTCGTCGTATCCCGCGCCCCGGCGATTCCGGCACCGGGGAAAGCCATCGGCGTCAAGGAGTTCGCCCTGGCCCTCTTCG
GCAAGTACGGCGTGGCGGTGGAAGTCATTTCGATGCAGCTCCTTTTCGCGCTCGTCGGGGCGCTTTACCTGGCACGGAAG
CGATAG

Upstream 100 bases:

>100_bases
CACGGAAGTATGAACGCATGGGGTCTCTCCGGCGAAAAACTGCCGGGAGAGGCCCCTTTTTTTCTGCAATTTACCCCCGA
TATGGTAGATTTTATCCGAT

Downstream 100 bases:

>100_bases
GAACACTCGTGCCGAACAGGCGGCACGGTGCATATCAACCAAGGAGGAATGGCATGAAACATCTCAAGGGAATGGTTGTT
CTGCTGGCTGCAGTAGTGGC

Product: NADH-ubiquinone/plastoquinone oxidoreductase, chain 6

Products: NA

Alternate protein names: NADH dehydrogenase I subunit J; NDH-1 subunit J; NUO10 [H]

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MESALFYILAVVTVTGTAFAITEKHAVHAIVYLVTSFFALAVIFFLLGAPVVAIFEVIIYAGAIMVLFLFVIMMLDLGHP
ERARLPGIREWWPALALGAVTLASALALVVSRAPAIPAPGKAIGVKEFALALFGKYGVAVEVISMQLLFALVGALYLARK
R

Sequences:

>Translated_161_residues
MESALFYILAVVTVTGTAFAITEKHAVHAIVYLVTSFFALAVIFFLLGAPVVAIFEVIIYAGAIMVLFLFVIMMLDLGHP
ERARLPGIREWWPALALGAVTLASALALVVSRAPAIPAPGKAIGVKEFALALFGKYGVAVEVISMQLLFALVGALYLARK
R
>Mature_161_residues
MESALFYILAVVTVTGTAFAITEKHAVHAIVYLVTSFFALAVIFFLLGAPVVAIFEVIIYAGAIMVLFLFVIMMLDLGHP
ERARLPGIREWWPALALGAVTLASALALVVSRAPAIPAPGKAIGVKEFALALFGKYGVAVEVISMQLLFALVGALYLARK
R

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0839

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 6 (chain J)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 6 family [H]

Homologues:

Organism=Escherichia coli, GI1788616, Length=161, Percent_Identity=38.5093167701863, Blast_Score=93, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001457 [H]

Pfam domain/function: PF00499 Oxidored_q3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 17232; Mature: 17232

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESALFYILAVVTVTGTAFAITEKHAVHAIVYLVTSFFALAVIFFLLGAPVVAIFEVIIY
CCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AGAIMVLFLFVIMMLDLGHPERARLPGIREWWPALALGAVTLASALALVVSRAPAIPAPG
HHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
KAIGVKEFALALFGKYGVAVEVISMQLLFALVGALYLARKR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MESALFYILAVVTVTGTAFAITEKHAVHAIVYLVTSFFALAVIFFLLGAPVVAIFEVIIY
CCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AGAIMVLFLFVIMMLDLGHPERARLPGIREWWPALALGAVTLASALALVVSRAPAIPAPG
HHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
KAIGVKEFALALFGKYGVAVEVISMQLLFALVGALYLARKR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]