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The map label for this gene is nuoG [H]

Identifier: 78221384

GI number: 78221384

Start: 188964

End: 190892

Strand: Direct

Name: nuoG [H]

Synonym: Gmet_0159

Alternate gene names: 78221384

Gene position: 188964-190892 (Clockwise)

Preceding gene: 78221383

Following gene: 78221385

Centisome position: 4.73

GC content: 68.27

Gene sequence:

>1929_bases
ATGCCCAAGCTCATCATCGATCACATACCGGTTGAAGTCCCCGCCGGCACCAGCGTTCTGGAGGCGGCCAAGTCCGTCGG
GATCTGGATCCCCCACTTCTGCTACCATCCGGCCCTCGGAAGCGTGGGGGCCTGCCGGCTCTGCGCCGTGAAGATGCTGG
ACGGCCCGGTGAAGGGGATCCAGATGTCGTGCATGCTCCCGGCCCAGGACGGGATGGTGGTCTCCACCACCGACCCCGAG
GCCCTGAAGATGCGGAGCCTCGTCATCGAGTGGCTCATGACCAACCATCCCCACGACTGCCCGGTCTGCGACGAGGGGGG
TGAGTGCCTCCTCCAGGATTACACCGTCGCCGGGGGCCACGGCATCCGCCGCTACGAAGGGAAAAAGCGAACCCACGTGA
ACCAGTACCTTGGGCCGTACATCGAGCACGAGATGAATCGCTGCATCCAGTGCTACCGCTGCGTCCGGTTCTACCAGGAA
TACGCCGGCGGGAGCGACTTCGGCGTCATGGGAAACGCCCGGCGGGTTTACTACGGCCGCTTTGAGGAGGGGAAGCTCGA
ATCTCCCTTCTCCGGCACCCTCGTGGACATCTGCCCCACCGGCGTCTTCACCGACAAGACCGCCCGCTTCCGGGCCCGCT
ACTGGGACTACGAGATGGCCCCCTCGGTCTGCCCCCACTGTTCTCTGGGATGCAACACCGTGCCGGCGGCCCGCTACCGG
GAGCTCCTGAAAACCATTGCCCGGGAGAACCCCACCGTGAACGGCCCCTTCATCTGCGACCGGGGACGGTTCACCAATGC
CCCGGTGAACGACCCGGCGCGCCCCCGGGTGCCGCTGGTGGACAGGAAAGAGGTTTCGTGGGATGCGGCCCTGGATGCCC
TCATGGTGCGGGTCAGCGAACTGGAAGAGCTGTACGGCCCCGGGAGCCTGGCAGTGGTCGGCTCGCCCCGGCTCGCGCTG
GAGGGGAACATCCTGCTGGCGCGCCTGGCGGACCTCCTCGGCGCGGGGCACCTCTGCTACTTTACCGAGAAGGAGGAGGG
GGAGCGGACCGCCGCGGCAGTCGACCTCCTCGCCGGCGACAAAGCCGCCTCCATGGCGGACGTGCGGAAGGCCGACTGCG
TAGTCATCCTCGAAGCGGACCTCCGGGACGAGGGGCCCATGATGCTCCTGGCGGTCCGGCAGGCATGGCGCCACGGCGCG
CCGGTCTTCCTGGTGGGGAAGCACGCCCCCCTGGAGCAGGCCCGCACCGTCTCCATGGAAGCCATCGAGCTCAGCATCCT
CGAAGAGGTTCCCCTGGCCATCTTCGAGCGCCCCGTGGTCATCTGCGGGACCAGGAACAGCACCCGCGCCGCCATCGAAC
TCCTGGCCCGGGCCGATGCCAAGATCGCCTGCCTCCTCCCCGGCCCCAACGCCTTCGGAGCCAGGCTTCTGGCAAAGGAG
CACGGAGCGGTCGCCCTGGCCGAGGCCGTGGCCTCCGGAAAGGTGAAGGGGATCATCGCCGTGGAGGCAGACATCCCGGA
GGAGCTTCTGGCGCAAGTCCCCCTTATCGTCGCCGCCGACTGGCTCCCCACGGAGACGCTCCGGCGGGCCCAGGTGGTTC
TCCCCACGGCCGCCTGGGTAGAGATGGACGGCACCTTCGTCAACAACGAGGGGCGGGCACAGCGCTTCCGCAAGGCCATG
GTCCCCGGTCTCCCGATCCGGGGGCTCCCGGCCCGCTACCACGCCTCACCGGACAAGCCGGCGCCCTTCCATCCGCCCCG
GGTCCACCGCAGCGTTTCACCCGGCGGTGATACTCGCCCCGCCTGGCGGATCGTGGCGGAACTCATGGAGCGGTGCGGAG
GGGAGACAGAGACTGACCCCTTTGTGGGGCGGTGGGAGGTGTTGCGGGGGCTCGATCCGGAGGGAGATGGGGTGAGGCTG
AGAGGGTGA

Upstream 100 bases:

>100_bases
CGGCATCGGCATCATCATCACCCTCGGCTGGGGAAGCCTCGTCATGGCGCTCCAGTACGACCGGGAACGGCCCCGGGTGA
TCATCCTGTAGCGAGAGACC

Downstream 100 bases:

>100_bases
TACGTGTCCCGTTTGTGGAGATGAGCGCGCACGTGAACCGCTCAAGCGTGGGGACAGGCATTGACTGATTTGACATCTTG
AAAGGGAGAAGGCTTTCCTA

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 642; Mature: 641

Protein sequence:

>642_residues
MPKLIIDHIPVEVPAGTSVLEAAKSVGIWIPHFCYHPALGSVGACRLCAVKMLDGPVKGIQMSCMLPAQDGMVVSTTDPE
ALKMRSLVIEWLMTNHPHDCPVCDEGGECLLQDYTVAGGHGIRRYEGKKRTHVNQYLGPYIEHEMNRCIQCYRCVRFYQE
YAGGSDFGVMGNARRVYYGRFEEGKLESPFSGTLVDICPTGVFTDKTARFRARYWDYEMAPSVCPHCSLGCNTVPAARYR
ELLKTIARENPTVNGPFICDRGRFTNAPVNDPARPRVPLVDRKEVSWDAALDALMVRVSELEELYGPGSLAVVGSPRLAL
EGNILLARLADLLGAGHLCYFTEKEEGERTAAAVDLLAGDKAASMADVRKADCVVILEADLRDEGPMMLLAVRQAWRHGA
PVFLVGKHAPLEQARTVSMEAIELSILEEVPLAIFERPVVICGTRNSTRAAIELLARADAKIACLLPGPNAFGARLLAKE
HGAVALAEAVASGKVKGIIAVEADIPEELLAQVPLIVAADWLPTETLRRAQVVLPTAAWVEMDGTFVNNEGRAQRFRKAM
VPGLPIRGLPARYHASPDKPAPFHPPRVHRSVSPGGDTRPAWRIVAELMERCGGETETDPFVGRWEVLRGLDPEGDGVRL
RG

Sequences:

>Translated_642_residues
MPKLIIDHIPVEVPAGTSVLEAAKSVGIWIPHFCYHPALGSVGACRLCAVKMLDGPVKGIQMSCMLPAQDGMVVSTTDPE
ALKMRSLVIEWLMTNHPHDCPVCDEGGECLLQDYTVAGGHGIRRYEGKKRTHVNQYLGPYIEHEMNRCIQCYRCVRFYQE
YAGGSDFGVMGNARRVYYGRFEEGKLESPFSGTLVDICPTGVFTDKTARFRARYWDYEMAPSVCPHCSLGCNTVPAARYR
ELLKTIARENPTVNGPFICDRGRFTNAPVNDPARPRVPLVDRKEVSWDAALDALMVRVSELEELYGPGSLAVVGSPRLAL
EGNILLARLADLLGAGHLCYFTEKEEGERTAAAVDLLAGDKAASMADVRKADCVVILEADLRDEGPMMLLAVRQAWRHGA
PVFLVGKHAPLEQARTVSMEAIELSILEEVPLAIFERPVVICGTRNSTRAAIELLARADAKIACLLPGPNAFGARLLAKE
HGAVALAEAVASGKVKGIIAVEADIPEELLAQVPLIVAADWLPTETLRRAQVVLPTAAWVEMDGTFVNNEGRAQRFRKAM
VPGLPIRGLPARYHASPDKPAPFHPPRVHRSVSPGGDTRPAWRIVAELMERCGGETETDPFVGRWEVLRGLDPEGDGVRL
RG
>Mature_641_residues
PKLIIDHIPVEVPAGTSVLEAAKSVGIWIPHFCYHPALGSVGACRLCAVKMLDGPVKGIQMSCMLPAQDGMVVSTTDPEA
LKMRSLVIEWLMTNHPHDCPVCDEGGECLLQDYTVAGGHGIRRYEGKKRTHVNQYLGPYIEHEMNRCIQCYRCVRFYQEY
AGGSDFGVMGNARRVYYGRFEEGKLESPFSGTLVDICPTGVFTDKTARFRARYWDYEMAPSVCPHCSLGCNTVPAARYRE
LLKTIARENPTVNGPFICDRGRFTNAPVNDPARPRVPLVDRKEVSWDAALDALMVRVSELEELYGPGSLAVVGSPRLALE
GNILLARLADLLGAGHLCYFTEKEEGERTAAAVDLLAGDKAASMADVRKADCVVILEADLRDEGPMMLLAVRQAWRHGAP
VFLVGKHAPLEQARTVSMEAIELSILEEVPLAIFERPVVICGTRNSTRAAIELLARADAKIACLLPGPNAFGARLLAKEH
GAVALAEAVASGKVKGIIAVEADIPEELLAQVPLIVAADWLPTETLRRAQVVLPTAAWVEMDGTFVNNEGRAQRFRKAMV
PGLPIRGLPARYHASPDKPAPFHPPRVHRSVSPGGDTRPAWRIVAELMERCGGETETDPFVGRWEVLRGLDPEGDGVRLR
G

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=598, Percent_Identity=29.2642140468227, Blast_Score=235, Evalue=9e-62,
Organism=Escherichia coli, GI145693161, Length=642, Percent_Identity=38.6292834890966, Blast_Score=397, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17565758, Length=639, Percent_Identity=28.4820031298905, Blast_Score=216, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI32566231, Length=581, Percent_Identity=29.6041308089501, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI193209088, Length=271, Percent_Identity=38.0073800738007, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24640559, Length=643, Percent_Identity=28.6158631415241, Blast_Score=224, Evalue=2e-58,
Organism=Drosophila melanogaster, GI24640557, Length=643, Percent_Identity=28.6158631415241, Blast_Score=224, Evalue=2e-58,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574 [H]

Pfam domain/function: PF00111 Fer2; PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 70187; Mature: 70056

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKLIIDHIPVEVPAGTSVLEAAKSVGIWIPHFCYHPALGSVGACRLCAVKMLDGPVKGI
CCCEEEECCCEECCCCHHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHHHCCCCCCE
QMSCMLPAQDGMVVSTTDPEALKMRSLVIEWLMTNHPHDCPVCDEGGECLLQDYTVAGGH
EEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCC
GIRRYEGKKRTHVNQYLGPYIEHEMNRCIQCYRCVRFYQEYAGGSDFGVMGNARRVYYGR
CEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEC
FEEGKLESPFSGTLVDICPTGVFTDKTARFRARYWDYEMAPSVCPHCSLGCNTVPAARYR
CCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHH
ELLKTIARENPTVNGPFICDRGRFTNAPVNDPARPRVPLVDRKEVSWDAALDALMVRVSE
HHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LEELYGPGSLAVVGSPRLALEGNILLARLADLLGAGHLCYFTEKEEGERTAAAVDLLAGD
HHHHHCCCCEEEECCCCEEEECCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCC
KAASMADVRKADCVVILEADLRDEGPMMLLAVRQAWRHGAPVFLVGKHAPLEQARTVSME
CHHHHHHHCCCCEEEEEECCCCCCCCEEHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
AIELSILEEVPLAIFERPVVICGTRNSTRAAIELLARADAKIACLLPGPNAFGARLLAKE
HHHHHHHHHCCHHHHCCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHH
HGAVALAEAVASGKVKGIIAVEADIPEELLAQVPLIVAADWLPTETLRRAQVVLPTAAWV
CCCHHHHHHHHCCCEEEEEEEECCCCHHHHHHCCCEEEECCCCHHHHHHCEEEECCCCEE
EMDGTFVNNEGRAQRFRKAMVPGLPIRGLPARYHASPDKPAPFHPPRVHRSVSPGGDTRP
EECCEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCH
AWRIVAELMERCGGETETDPFVGRWEVLRGLDPEGDGVRLRG
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCEEECC
>Mature Secondary Structure 
PKLIIDHIPVEVPAGTSVLEAAKSVGIWIPHFCYHPALGSVGACRLCAVKMLDGPVKGI
CCEEEECCCEECCCCHHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHHHCCCCCCE
QMSCMLPAQDGMVVSTTDPEALKMRSLVIEWLMTNHPHDCPVCDEGGECLLQDYTVAGGH
EEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCC
GIRRYEGKKRTHVNQYLGPYIEHEMNRCIQCYRCVRFYQEYAGGSDFGVMGNARRVYYGR
CEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEC
FEEGKLESPFSGTLVDICPTGVFTDKTARFRARYWDYEMAPSVCPHCSLGCNTVPAARYR
CCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHH
ELLKTIARENPTVNGPFICDRGRFTNAPVNDPARPRVPLVDRKEVSWDAALDALMVRVSE
HHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LEELYGPGSLAVVGSPRLALEGNILLARLADLLGAGHLCYFTEKEEGERTAAAVDLLAGD
HHHHHCCCCEEEECCCCEEEECCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCC
KAASMADVRKADCVVILEADLRDEGPMMLLAVRQAWRHGAPVFLVGKHAPLEQARTVSME
CHHHHHHHCCCCEEEEEECCCCCCCCEEHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
AIELSILEEVPLAIFERPVVICGTRNSTRAAIELLARADAKIACLLPGPNAFGARLLAKE
HHHHHHHHHCCHHHHCCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHH
HGAVALAEAVASGKVKGIIAVEADIPEELLAQVPLIVAADWLPTETLRRAQVVLPTAAWV
CCCHHHHHHHHCCCEEEEEEEECCCCHHHHHHCCCEEEECCCCHHHHHHCEEEECCCCEE
EMDGTFVNNEGRAQRFRKAMVPGLPIRGLPARYHASPDKPAPFHPPRVHRSVSPGGDTRP
EECCEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCH
AWRIVAELMERCGGETETDPFVGRWEVLRGLDPEGDGVRLRG
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12118882 [H]