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The map label for this gene is kup2

Identifier: 78221267

GI number: 78221267

Start: 49639

End: 51459

Strand: Reverse

Name: kup2

Synonym: Gmet_0039

Alternate gene names: 78221267

Gene position: 51459-49639 (Counterclockwise)

Preceding gene: 78221273

Following gene: 78221266

Centisome position: 1.29

GC content: 60.24

Gene sequence:

>1821_bases
ATGGTGCAGGAACACACGGAATCGTTCTGGGGCGGAATCATCAAGTCCATGGGGCTTGTTTTCGGCGACATCGGCACGAG
CCCCATCTATACCCTCACGGTCATCATGACCCTGACGAAACCGGACGCCGAGCATGTCCTCGGCATCCTCTCCCTCATCG
TCTGGACCCTCATCATCCTCGTCTCCGTGGAGTATGCCTGGCTCGCCATGAGTCTCGGCCGCAAGGGAGAGGGGGGGACC
ATCGTTCTCAAGGAGATCCTGGTCCGGCTCCTGAAATCGGGGCGCCAGGTGGCCTTCGTCGGCTTTCTTGCCTTCATGGG
GGTCTCGCTCCTGCTGGGGGACGGCATCATCACCCCGGCCATCAGTATCCTCTCCGCCGTGGAGGGGATGCGGCTGATCC
CGGGATGGGAGAACCTTGCCCAGGGGGTCCTGATTTTCATTGCGGCGGTCATCGCCCTCATCCTGTTCATCTTCCAGTTC
AAGGGAACCGACAAGGTGGCCGGCGCCTTCGGGCCGATCATGGTCATCTGGTTCGGCGCCCTGACTCTGTCGGGGATCGT
GTCGATCGCCGGCACTCCGGAGGTCGTCAGCGCGGTGAGCCCCCATCACGCCGTGACCTTCCTGATGCACAACGGCCTGG
CCGGGTTCTTCATCCTCTCGGAGGTGATCCTCTGCGCCACCGGGGGAGAGGCCCTCTACGCCGACATGGGGCACCTGGGG
CGAAAGCCGATCATCCGGGCCTGGTACTTCGTCTTCAGCGCCCTGGTCATCAACTACCTGGGGCAGGGGGCCTTCATCCT
GAGAAACCCCAACGAAACGAACATTCTCTTCTCCATGGTGAAGAGCCAGGCGCCCATTCTCTACATTCCCTTCCTCTGCC
TCACCATCATGGCCACCATCATCGCATCCCAGGCCCTCATCAGCGGGGTCTTCTCCATCGTCTACCAGGGGATCACCACC
CGGATCCTCCCCCTCATGAAGGTGGATTACACCTCCACGCACCTGAAATCCCAGATATACATCGGCTCCGTCAACTGGTC
ACTGCTAGTGGCGGTCATCTTCATCATGCTCATTTTCAAGAAATCGGAAAACCTGGCCGCGGCCTACGGCCTGGCGGTCA
CCGGCACCATGTTCATCACCGGCATCATGATGACCATGATCTTCTCCCACACCACCAAAAAGTGGAAGGTCCCCATCGCC
CTCGCGGTGACCCTCATCGACCTGGTCTACCTGACGGCCAACTTCCACAAGCTCCCCCACGGCGGCTACTGGTCCCTGAT
CCTTGCCTCGATTCCCCTGGCGATCATGATCATCTGGACCCAGGGGCAAAAGGCACTCTACCGGGCGCTCAGGCCCCTGG
ACCTGGACACGTTCCTCCTCTCCTTCGGGCAAATCTACGCCAAGGGGCACAACATTCCCGGCACCGGACTTTTCTTCGTG
CGGGAGACGGCGGTGGTCCCCCCCTATGTGATCCACTGCATCATCCGGAGCAACATCATCTACGAACGGAACGTCTTCGT
CTCCCTGAACCGCTCCGACGAGCCCTTTGGCGTCAAGGCCAATCTCACGAAGGGGATCGGGCCGGGGCTCGACAGTTTCG
AGATCCTCGCCGGCTACATGGAGCTGGTTGACATCGAGCGGCTCCTCAAGAAGAAGGGAATCGAGGAGAAGGTCATCTTC
TACGGCATCGAGGACATCGCCACCAACAACCCTTTCTGGCGCGTTTTCTCAACCATCAAGCGGCAGACCGCCAACTTCGT
CCAGTTCAACAAGCTGCCGGTCAGCAAGCTGCAGGGTGTTGTGACGCGGGTGGAGATGTAA

Upstream 100 bases:

>100_bases
CTTGTGCCGCCGTGTGCTAAGTGATATAAGGGGCCGGCTGTATACATTGGCTCGCATCCCGATGCTCGGCACCGGCTCGC
GAGCCTTGGAGGATGCACGG

Downstream 100 bases:

>100_bases
TCCGAGGAGGGGACGGGCCATGGACCAGCATAAGGGAGACGCCTCACTGGGTGGAATCGTCAAGGCGCTCGGCCTCGTCT
TCGGCGACATCGGCACGAGC

Product: K+ potassium transporter

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 606; Mature: 606

Protein sequence:

>606_residues
MVQEHTESFWGGIIKSMGLVFGDIGTSPIYTLTVIMTLTKPDAEHVLGILSLIVWTLIILVSVEYAWLAMSLGRKGEGGT
IVLKEILVRLLKSGRQVAFVGFLAFMGVSLLLGDGIITPAISILSAVEGMRLIPGWENLAQGVLIFIAAVIALILFIFQF
KGTDKVAGAFGPIMVIWFGALTLSGIVSIAGTPEVVSAVSPHHAVTFLMHNGLAGFFILSEVILCATGGEALYADMGHLG
RKPIIRAWYFVFSALVINYLGQGAFILRNPNETNILFSMVKSQAPILYIPFLCLTIMATIIASQALISGVFSIVYQGITT
RILPLMKVDYTSTHLKSQIYIGSVNWSLLVAVIFIMLIFKKSENLAAAYGLAVTGTMFITGIMMTMIFSHTTKKWKVPIA
LAVTLIDLVYLTANFHKLPHGGYWSLILASIPLAIMIIWTQGQKALYRALRPLDLDTFLLSFGQIYAKGHNIPGTGLFFV
RETAVVPPYVIHCIIRSNIIYERNVFVSLNRSDEPFGVKANLTKGIGPGLDSFEILAGYMELVDIERLLKKKGIEEKVIF
YGIEDIATNNPFWRVFSTIKRQTANFVQFNKLPVSKLQGVVTRVEM

Sequences:

>Translated_606_residues
MVQEHTESFWGGIIKSMGLVFGDIGTSPIYTLTVIMTLTKPDAEHVLGILSLIVWTLIILVSVEYAWLAMSLGRKGEGGT
IVLKEILVRLLKSGRQVAFVGFLAFMGVSLLLGDGIITPAISILSAVEGMRLIPGWENLAQGVLIFIAAVIALILFIFQF
KGTDKVAGAFGPIMVIWFGALTLSGIVSIAGTPEVVSAVSPHHAVTFLMHNGLAGFFILSEVILCATGGEALYADMGHLG
RKPIIRAWYFVFSALVINYLGQGAFILRNPNETNILFSMVKSQAPILYIPFLCLTIMATIIASQALISGVFSIVYQGITT
RILPLMKVDYTSTHLKSQIYIGSVNWSLLVAVIFIMLIFKKSENLAAAYGLAVTGTMFITGIMMTMIFSHTTKKWKVPIA
LAVTLIDLVYLTANFHKLPHGGYWSLILASIPLAIMIIWTQGQKALYRALRPLDLDTFLLSFGQIYAKGHNIPGTGLFFV
RETAVVPPYVIHCIIRSNIIYERNVFVSLNRSDEPFGVKANLTKGIGPGLDSFEILAGYMELVDIERLLKKKGIEEKVIF
YGIEDIATNNPFWRVFSTIKRQTANFVQFNKLPVSKLQGVVTRVEM
>Mature_606_residues
MVQEHTESFWGGIIKSMGLVFGDIGTSPIYTLTVIMTLTKPDAEHVLGILSLIVWTLIILVSVEYAWLAMSLGRKGEGGT
IVLKEILVRLLKSGRQVAFVGFLAFMGVSLLLGDGIITPAISILSAVEGMRLIPGWENLAQGVLIFIAAVIALILFIFQF
KGTDKVAGAFGPIMVIWFGALTLSGIVSIAGTPEVVSAVSPHHAVTFLMHNGLAGFFILSEVILCATGGEALYADMGHLG
RKPIIRAWYFVFSALVINYLGQGAFILRNPNETNILFSMVKSQAPILYIPFLCLTIMATIIASQALISGVFSIVYQGITT
RILPLMKVDYTSTHLKSQIYIGSVNWSLLVAVIFIMLIFKKSENLAAAYGLAVTGTMFITGIMMTMIFSHTTKKWKVPIA
LAVTLIDLVYLTANFHKLPHGGYWSLILASIPLAIMIIWTQGQKALYRALRPLDLDTFLLSFGQIYAKGHNIPGTGLFFV
RETAVVPPYVIHCIIRSNIIYERNVFVSLNRSDEPFGVKANLTKGIGPGLDSFEILAGYMELVDIERLLKKKGIEEKVIF
YGIEDIATNNPFWRVFSTIKRQTANFVQFNKLPVSKLQGVVTRVEM

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=568, Percent_Identity=34.5070422535211, Blast_Score=300, Evalue=2e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP2_GEOMG (Q39ZN5)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_383014.1
- STRING:   Q39ZN5
- GeneID:   3739616
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_0039
- NMPDR:   fig|269799.3.peg.103
- eggNOG:   COG3158
- HOGENOM:   HBG351154
- OMA:   IMMTMIF
- PhylomeDB:   Q39ZN5
- ProtClustDB:   CLSK900490
- BioCyc:   GMET269799:GMET_0039-MONOMER
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 66612; Mature: 66612

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf222af8)-; HASH(0xf15df48)-; HASH(0xc656778)-; HASH(0xe31fcf4)-; HASH(0xcb5e980)-; HASH(0xee0d2a0)-; HASH(0xe5b62b4)-; HASH(0xef69354)-; HASH(0xe5b6188)-; HASH(0xc72e850)-; HASH(0xc702280)-; HASH(0xf9f6fe0)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQEHTESFWGGIIKSMGLVFGDIGTSPIYTLTVIMTLTKPDAEHVLGILSLIVWTLIIL
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHH
VSVEYAWLAMSLGRKGEGGTIVLKEILVRLLKSGRQVAFVGFLAFMGVSLLLGDGIITPA
HHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHH
ISILSAVEGMRLIPGWENLAQGVLIFIAAVIALILFIFQFKGTDKVAGAFGPIMVIWFGA
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LTLSGIVSIAGTPEVVSAVSPHHAVTFLMHNGLAGFFILSEVILCATGGEALYADMGHLG
HHHHHHHHCCCCHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHCC
RKPIIRAWYFVFSALVINYLGQGAFILRNPNETNILFSMVKSQAPILYIPFLCLTIMATI
CCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHH
IASQALISGVFSIVYQGITTRILPLMKVDYTSTHLKSQIYIGSVNWSLLVAVIFIMLIFK
HHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHCCEEEEECCCHHHHHHHHHHHHHHH
KSENLAAAYGLAVTGTMFITGIMMTMIFSHTTKKWKVPIALAVTLIDLVYLTANFHKLPH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHCCCCCC
GGYWSLILASIPLAIMIIWTQGQKALYRALRPLDLDTFLLSFGQIYAKGHNIPGTGLFFV
CCHHHHHHHHCCEEEEEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCEEEE
RETAVVPPYVIHCIIRSNIIYERNVFVSLNRSDEPFGVKANLTKGIGPGLDSFEILAGYM
ECCCCCCHHHHHHHHHCCEEEECEEEEEECCCCCCCCEEECCCCCCCCCCCHHHHHHHHH
ELVDIERLLKKKGIEEKVIFYGIEDIATNNPFWRVFSTIKRQTANFVQFNKLPVSKLQGV
HHHHHHHHHHHCCCCCEEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHEECCCCHHHHHHH
VTRVEM
HHHCCH
>Mature Secondary Structure
MVQEHTESFWGGIIKSMGLVFGDIGTSPIYTLTVIMTLTKPDAEHVLGILSLIVWTLIIL
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHH
VSVEYAWLAMSLGRKGEGGTIVLKEILVRLLKSGRQVAFVGFLAFMGVSLLLGDGIITPA
HHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHH
ISILSAVEGMRLIPGWENLAQGVLIFIAAVIALILFIFQFKGTDKVAGAFGPIMVIWFGA
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LTLSGIVSIAGTPEVVSAVSPHHAVTFLMHNGLAGFFILSEVILCATGGEALYADMGHLG
HHHHHHHHCCCCHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHCC
RKPIIRAWYFVFSALVINYLGQGAFILRNPNETNILFSMVKSQAPILYIPFLCLTIMATI
CCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHH
IASQALISGVFSIVYQGITTRILPLMKVDYTSTHLKSQIYIGSVNWSLLVAVIFIMLIFK
HHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHCCEEEEECCCHHHHHHHHHHHHHHH
KSENLAAAYGLAVTGTMFITGIMMTMIFSHTTKKWKVPIALAVTLIDLVYLTANFHKLPH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHCCCCCC
GGYWSLILASIPLAIMIIWTQGQKALYRALRPLDLDTFLLSFGQIYAKGHNIPGTGLFFV
CCHHHHHHHHCCEEEEEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCEEEE
RETAVVPPYVIHCIIRSNIIYERNVFVSLNRSDEPFGVKANLTKGIGPGLDSFEILAGYM
ECCCCCCHHHHHHHHHCCEEEECEEEEEECCCCCCCCEEECCCCCCCCCCCHHHHHHHHH
ELVDIERLLKKKGIEEKVIFYGIEDIATNNPFWRVFSTIKRQTANFVQFNKLPVSKLQGV
HHHHHHHHHHHCCCCCEEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHEECCCCHHHHHHH
VTRVEM
HHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA