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The map label for this gene is kup1

Identifier: 78221266

GI number: 78221266

Start: 47802

End: 49619

Strand: Reverse

Name: kup1

Synonym: Gmet_0038

Alternate gene names: 78221266

Gene position: 49619-47802 (Counterclockwise)

Preceding gene: 78221267

Following gene: 78221265

Centisome position: 1.24

GC content: 62.38

Gene sequence:

>1818_bases
ATGGACCAGCATAAGGGAGACGCCTCACTGGGTGGAATCGTCAAGGCGCTCGGCCTCGTCTTCGGCGACATCGGCACGAG
CCCCATTTATACCCTTACCGTCATCTTCACCCTGACCCAGCCGACGAGGGAGAACGTCTTCGGCATCCTGTCGCTGGTCT
TCTGGACTATGACGATCCTGGTGACCATGGAGTACGCCTGGCTCGCCATGAGCCTGGGACGCAAGGGGCAGGGGGGGGAG
ATCGTCCTGCGGGAGATCATCATGAAGCTGGTGAAGACGGGGCGTCTCGTGGCCTTTGCCGGCTTCCTCTCCTTCGTGGG
GGTATCGCTCCTGCTGGGTGACGGGGTTATCACCCCCGCCATCAGTATCCTCTCCGCCGTGGAGGGGCTCCTCCTGATCC
CCGGCCTCGAAGGGCTCTCCACCGGGACCCTTGTCGCCATCGCCGCCGCCATCGCCATCGGCCTCTTCTCAGTCCAGTTC
AAGGGGACCGACCGGGTGGCCGGCGCCTTCGGCCCCATCATGGCGGTCTGGTTCAGCACCCTCGCCGTCACCGGCGTCGT
TTCCGCCCTCTCCATGCCCGAGATTGTGGAGGCGATCAACCCGTGGCACGCCTTCACCTTCTTCCGGGAGAACGGTCTGG
CCGGCTACTTCGTTCTCTCCGAGGTGATCCTCTGCTCCACGGGGGGCGAGGCCCTTTACGCCGACATGGGACACCTGGGG
CGCCGCCCCATCGTCAAGTCGTGGTACTTTGTCTTCATGGCCCTCTACCTCAACTACCTGGGGCAGGGGGTCTTCGCCAT
TACCCACCCGGAGGCGAAAAACCTCCTCTTCGGCATGGTCCGGGATCAGATGCCGACCCTCTACATCCCGTTCCTCATTC
TCACCATCATGGCCACCATCATCGCCTCCCAGTCCATCATCAGCGGGGTCTTCTCCATCGTCTACCAGGGGATCACCACA
CGGCTCCTGCCGCTCATGCGGGTCGACTACACCTCCCGGGAGATCAAATCCCAGATATACCTGGGGGCCGTCAACTGGTC
CCTCATGGTGGCGGTCATCCTCGTGATGCTCCTTTTCCGCAAGTCCGAGAACCTGGCCGCCGCCTACGGCATGGCGGTCA
CCGGCTCCATGACCATCACCGGCATCATGATGATCATCGTCTTCGCCCACACCACCAAGAAGTGGCGGGCCCTGGTGGCC
CTGGTGATCACCCTCATCGACGCCGCGTACCTCCTCTCCACTTTCTCCAAGATCCCCCACGGAGCCTACTGGTCCCTGAT
CCTGGCGTCGATCCCCTTTGTCACCATCATCATCTGGACCCGGGGACAGCGCTCCCTCTACCACGCCCTGAAACCCCTCG
ACCTAGAGACTTTCCTCATCTCCTACGAGCAGATTTATGCCAAGGGGCCCATCCGGGGGACCGGACTCTTCTTCACCCGC
GATACCGACGTGGTCCCCCCCTACGTGGTCCACTGCATCATCCGGAGCAACATCATCTACGAGCGCAACGTCTTCATCTC
CCTCGTCATCACCGACGAGCCCCTGGGGGTCGAGACCGAGCTGATCAAGGGGATCGGGCCGGGGCTTGACGCCTTCCGGA
TCGAGGCCGGATACATGGAGGTGGTGGACATTGAGGCGCTCCTCAAGGCGAACGGCATCCAGGAGAAGGTCATCTTCTAC
GGGGTCGAGGACATCTCCACCCGCAACCCCCTCTGGCGGGTCTTCTCGGTCTTCAAAAAGCTCACCCCAAATTTCGTCCA
GTTCCACAAGCTGCCGGCCAGCCGCCTCCAGGGTGTCGTGACGCGGGTGGAGATGTAA

Upstream 100 bases:

>100_bases
CGGCAGACCGCCAACTTCGTCCAGTTCAACAAGCTGCCGGTCAGCAAGCTGCAGGGTGTTGTGACGCGGGTGGAGATGTA
ATCCGAGGAGGGGACGGGCC

Downstream 100 bases:

>100_bases
TACTTCCACGCCTTTCCCTTCCATTGACAAGCACGCCTCGCGCCTTAGAATTACCTTACAAACCGCGACAGAGGAGTCCT
TCAATGAAAACAACTATCGC

Product: K+ potassium transporter

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 605; Mature: 605

Protein sequence:

>605_residues
MDQHKGDASLGGIVKALGLVFGDIGTSPIYTLTVIFTLTQPTRENVFGILSLVFWTMTILVTMEYAWLAMSLGRKGQGGE
IVLREIIMKLVKTGRLVAFAGFLSFVGVSLLLGDGVITPAISILSAVEGLLLIPGLEGLSTGTLVAIAAAIAIGLFSVQF
KGTDRVAGAFGPIMAVWFSTLAVTGVVSALSMPEIVEAINPWHAFTFFRENGLAGYFVLSEVILCSTGGEALYADMGHLG
RRPIVKSWYFVFMALYLNYLGQGVFAITHPEAKNLLFGMVRDQMPTLYIPFLILTIMATIIASQSIISGVFSIVYQGITT
RLLPLMRVDYTSREIKSQIYLGAVNWSLMVAVILVMLLFRKSENLAAAYGMAVTGSMTITGIMMIIVFAHTTKKWRALVA
LVITLIDAAYLLSTFSKIPHGAYWSLILASIPFVTIIIWTRGQRSLYHALKPLDLETFLISYEQIYAKGPIRGTGLFFTR
DTDVVPPYVVHCIIRSNIIYERNVFISLVITDEPLGVETELIKGIGPGLDAFRIEAGYMEVVDIEALLKANGIQEKVIFY
GVEDISTRNPLWRVFSVFKKLTPNFVQFHKLPASRLQGVVTRVEM

Sequences:

>Translated_605_residues
MDQHKGDASLGGIVKALGLVFGDIGTSPIYTLTVIFTLTQPTRENVFGILSLVFWTMTILVTMEYAWLAMSLGRKGQGGE
IVLREIIMKLVKTGRLVAFAGFLSFVGVSLLLGDGVITPAISILSAVEGLLLIPGLEGLSTGTLVAIAAAIAIGLFSVQF
KGTDRVAGAFGPIMAVWFSTLAVTGVVSALSMPEIVEAINPWHAFTFFRENGLAGYFVLSEVILCSTGGEALYADMGHLG
RRPIVKSWYFVFMALYLNYLGQGVFAITHPEAKNLLFGMVRDQMPTLYIPFLILTIMATIIASQSIISGVFSIVYQGITT
RLLPLMRVDYTSREIKSQIYLGAVNWSLMVAVILVMLLFRKSENLAAAYGMAVTGSMTITGIMMIIVFAHTTKKWRALVA
LVITLIDAAYLLSTFSKIPHGAYWSLILASIPFVTIIIWTRGQRSLYHALKPLDLETFLISYEQIYAKGPIRGTGLFFTR
DTDVVPPYVVHCIIRSNIIYERNVFISLVITDEPLGVETELIKGIGPGLDAFRIEAGYMEVVDIEALLKANGIQEKVIFY
GVEDISTRNPLWRVFSVFKKLTPNFVQFHKLPASRLQGVVTRVEM
>Mature_605_residues
MDQHKGDASLGGIVKALGLVFGDIGTSPIYTLTVIFTLTQPTRENVFGILSLVFWTMTILVTMEYAWLAMSLGRKGQGGE
IVLREIIMKLVKTGRLVAFAGFLSFVGVSLLLGDGVITPAISILSAVEGLLLIPGLEGLSTGTLVAIAAAIAIGLFSVQF
KGTDRVAGAFGPIMAVWFSTLAVTGVVSALSMPEIVEAINPWHAFTFFRENGLAGYFVLSEVILCSTGGEALYADMGHLG
RRPIVKSWYFVFMALYLNYLGQGVFAITHPEAKNLLFGMVRDQMPTLYIPFLILTIMATIIASQSIISGVFSIVYQGITT
RLLPLMRVDYTSREIKSQIYLGAVNWSLMVAVILVMLLFRKSENLAAAYGMAVTGSMTITGIMMIIVFAHTTKKWRALVA
LVITLIDAAYLLSTFSKIPHGAYWSLILASIPFVTIIIWTRGQRSLYHALKPLDLETFLISYEQIYAKGPIRGTGLFFTR
DTDVVPPYVVHCIIRSNIIYERNVFISLVITDEPLGVETELIKGIGPGLDAFRIEAGYMEVVDIEALLKANGIQEKVIFY
GVEDISTRNPLWRVFSVFKKLTPNFVQFHKLPASRLQGVVTRVEM

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=554, Percent_Identity=34.6570397111913, Blast_Score=288, Evalue=5e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP1_GEOMG (Q39ZN6)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_383013.1
- STRING:   Q39ZN6
- GeneID:   3739615
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_0038
- NMPDR:   fig|269799.3.peg.102
- eggNOG:   COG3158
- HOGENOM:   HBG351154
- OMA:   HGAYWSI
- PhylomeDB:   Q39ZN6
- ProtClustDB:   CLSK900490
- BioCyc:   GMET269799:GMET_0038-MONOMER
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 66479; Mature: 66479

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe86a084)-; HASH(0xf159e6c)-; HASH(0xb6ddcb0)-; HASH(0xf9a19bc)-; HASH(0xdf44214)-; HASH(0xeecd79c)-; HASH(0xf228aec)-; HASH(0xf47a7b0)-; HASH(0xab15158)-; HASH(0xf47340c)-; HASH(0xf22eb40)-; HASH(0xf479c88)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQHKGDASLGGIVKALGLVFGDIGTSPIYTLTVIFTLTQPTRENVFGILSLVFWTMTIL
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHH
VTMEYAWLAMSLGRKGQGGEIVLREIIMKLVKTGRLVAFAGFLSFVGVSLLLGDGVITPA
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHH
ISILSAVEGLLLIPGLEGLSTGTLVAIAAAIAIGLFSVQFKGTDRVAGAFGPIMAVWFST
HHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHH
LAVTGVVSALSMPEIVEAINPWHAFTFFRENGLAGYFVLSEVILCSTGGEALYADMGHLG
HHHHHHHHHHCHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCC
RRPIVKSWYFVFMALYLNYLGQGVFAITHPEAKNLLFGMVRDQMPTLYIPFLILTIMATI
CCCHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
IASQSIISGVFSIVYQGITTRLLPLMRVDYTSREIKSQIYLGAVNWSLMVAVILVMLLFR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEECCHHHHHHHHHHHHHHH
KSENLAAAYGMAVTGSMTITGIMMIIVFAHTTKKWRALVALVITLIDAAYLLSTFSKIPH
CCCCHHHHHCCCEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GAYWSLILASIPFVTIIIWTRGQRSLYHALKPLDLETFLISYEQIYAKGPIRGTGLFFTR
CHHHHHHHHHCCEEEEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEC
DTDVVPPYVVHCIIRSNIIYERNVFISLVITDEPLGVETELIKGIGPGLDAFRIEAGYME
CCCCCCHHHHHHHHHCCEEEECCEEEEEEEECCCCCCHHHHHHHCCCCCCCEEEECCCEE
VVDIEALLKANGIQEKVIFYGVEDISTRNPLWRVFSVFKKLTPNFVQFHKLPASRLQGVV
HHHHHHHHHCCCCCCEEEEEECHHCCCCCHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHH
TRVEM
HHCCH
>Mature Secondary Structure
MDQHKGDASLGGIVKALGLVFGDIGTSPIYTLTVIFTLTQPTRENVFGILSLVFWTMTIL
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHH
VTMEYAWLAMSLGRKGQGGEIVLREIIMKLVKTGRLVAFAGFLSFVGVSLLLGDGVITPA
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHH
ISILSAVEGLLLIPGLEGLSTGTLVAIAAAIAIGLFSVQFKGTDRVAGAFGPIMAVWFST
HHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHH
LAVTGVVSALSMPEIVEAINPWHAFTFFRENGLAGYFVLSEVILCSTGGEALYADMGHLG
HHHHHHHHHHCHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCC
RRPIVKSWYFVFMALYLNYLGQGVFAITHPEAKNLLFGMVRDQMPTLYIPFLILTIMATI
CCCHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
IASQSIISGVFSIVYQGITTRLLPLMRVDYTSREIKSQIYLGAVNWSLMVAVILVMLLFR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEECCHHHHHHHHHHHHHHH
KSENLAAAYGMAVTGSMTITGIMMIIVFAHTTKKWRALVALVITLIDAAYLLSTFSKIPH
CCCCHHHHHCCCEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GAYWSLILASIPFVTIIIWTRGQRSLYHALKPLDLETFLISYEQIYAKGPIRGTGLFFTR
CHHHHHHHHHCCEEEEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEC
DTDVVPPYVVHCIIRSNIIYERNVFISLVITDEPLGVETELIKGIGPGLDAFRIEAGYME
CCCCCCHHHHHHHHHCCEEEECCEEEEEEEECCCCCCHHHHHHHCCCCCCCEEEECCCEE
VVDIEALLKANGIQEKVIFYGVEDISTRNPLWRVFSVFKKLTPNFVQFHKLPASRLQGVV
HHHHHHHHHCCCCCCEEEEEECHHCCCCCHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHH
TRVEM
HHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA