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The map label for this gene is fur [H]

Identifier: 78189935

GI number: 78189935

Start: 2514742

End: 2515239

Strand: Reverse

Name: fur [H]

Synonym: Cag_1982

Alternate gene names: 78189935

Gene position: 2515239-2514742 (Counterclockwise)

Preceding gene: 78189936

Following gene: 78189934

Centisome position: 97.79

GC content: 42.77

Gene sequence:

>498_bases
ATGTTATTGACACTTTCCTTACTTATGCAATCAACGGGAGCCAACAATAATCTTGAGCAAGCTGAAAAGCTTTTTCGGCA
GCTCATGAAAGAACAAGGTTTTCGCTGCACCAACGAACGCATTGCCGTGTTGCACGAACTTTACAATGCCGAATCGCATC
TTGATGCTGATGAGCTTTATGTTCTGCTCAAGCAAAAACATGTTGCTATTTCACGCGCAACCGTTTACCACACCCTTCAC
CTGCTCTTTAAATTCCGCCTTATTTCAAAAATTGATCTTGGGCATAAACATGCTCATTACGAAAAAGCATATGGTGTAAC
CAACCACTTGCACATGGTGTGCAGCATTTGCGGACGAGTTACCGAAGTTGATGACAACCGCATTGCCCCACAATTGCAAG
AGATTTGTCGCCATAACGGGCTTAATTTAGAGCACTTTAGTTTACAGCTTGTAGGAACTTGCATTAAGCACGACTCTCCC
ATCCCAACGAATAATTAA

Upstream 100 bases:

>100_bases
CAGCAATTCCATTACGTGGTATTTTAAAGCTCATAGAGCAATAAAAGCGCTTCTTGCCAAATCCATATTTCTCCCCTTTT
CAACCACGAAAGGGGGAGAA

Downstream 100 bases:

>100_bases
GGATTTGTAACGCTCTGCCGAATATGCTTACCTTTACGGCTCTCGAATAAATGAACAGATTGAGGGAACTTAGCGGCTTT
AATTGCCTCATGGTTTGTCG

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MLLTLSLLMQSTGANNNLEQAEKLFRQLMKEQGFRCTNERIAVLHELYNAESHLDADELYVLLKQKHVAISRATVYHTLH
LLFKFRLISKIDLGHKHAHYEKAYGVTNHLHMVCSICGRVTEVDDNRIAPQLQEICRHNGLNLEHFSLQLVGTCIKHDSP
IPTNN

Sequences:

>Translated_165_residues
MLLTLSLLMQSTGANNNLEQAEKLFRQLMKEQGFRCTNERIAVLHELYNAESHLDADELYVLLKQKHVAISRATVYHTLH
LLFKFRLISKIDLGHKHAHYEKAYGVTNHLHMVCSICGRVTEVDDNRIAPQLQEICRHNGLNLEHFSLQLVGTCIKHDSP
IPTNN
>Mature_165_residues
MLLTLSLLMQSTGANNNLEQAEKLFRQLMKEQGFRCTNERIAVLHELYNAESHLDADELYVLLKQKHVAISRATVYHTLH
LLFKFRLISKIDLGHKHAHYEKAYGVTNHLHMVCSICGRVTEVDDNRIAPQLQEICRHNGLNLEHFSLQLVGTCIKHDSP
IPTNN

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 18935; Mature: 18935

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLTLSLLMQSTGANNNLEQAEKLFRQLMKEQGFRCTNERIAVLHELYNAESHLDADELY
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHH
VLLKQKHVAISRATVYHTLHLLFKFRLISKIDLGHKHAHYEKAYGVTNHLHMVCSICGRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHH
TEVDDNRIAPQLQEICRHNGLNLEHFSLQLVGTCIKHDSPIPTNN
HCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLLTLSLLMQSTGANNNLEQAEKLFRQLMKEQGFRCTNERIAVLHELYNAESHLDADELY
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHH
VLLKQKHVAISRATVYHTLHLLFKFRLISKIDLGHKHAHYEKAYGVTNHLHMVCSICGRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHH
TEVDDNRIAPQLQEICRHNGLNLEHFSLQLVGTCIKHDSPIPTNN
HCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083178 [H]